
Synaptic excitation of principal cells in the cat`s lateral geniculate
... same frequency as the early post-stimulus depolarizations and a later clonic phase with the same rhythm as the grouped potentials (Hedstrom and Lindstrom 1987). The rhythmic potentials in the principal cells were clearly prolonged EPSPs evoked by the epileptic burst discharges in a number of layer 6 ...
... same frequency as the early post-stimulus depolarizations and a later clonic phase with the same rhythm as the grouped potentials (Hedstrom and Lindstrom 1987). The rhythmic potentials in the principal cells were clearly prolonged EPSPs evoked by the epileptic burst discharges in a number of layer 6 ...
Molecular prosthetics for vision restoration based on freely
... Molecular prosthetics for vision restoration based on freely-diffusible and covalently bound photoswitches Light-regulated drugs allow remotely photoswitching biological activity and enable plausible therapies based on small molecules. We develop efficient compounds to manipulate neuronal activity f ...
... Molecular prosthetics for vision restoration based on freely-diffusible and covalently bound photoswitches Light-regulated drugs allow remotely photoswitching biological activity and enable plausible therapies based on small molecules. We develop efficient compounds to manipulate neuronal activity f ...
Lecture
... A disorder characterized by generalized and persistent free-floating anxiety (anxiety not restricted to any particular event or circumstance). The symptoms are variable, and can include muscle tension, continuous feelings of nervousness, trembling, sweating, lightheadedness, dizziness, palpitations. ...
... A disorder characterized by generalized and persistent free-floating anxiety (anxiety not restricted to any particular event or circumstance). The symptoms are variable, and can include muscle tension, continuous feelings of nervousness, trembling, sweating, lightheadedness, dizziness, palpitations. ...
The Nervous System
... body which has many effects, including smooth and coordinated muscle movement. So the disease would cause loss of muscle control. Diagnosis of PD is based primarily on a medical history and thorough neurological examination. Brain scans and/or lab tests may be performed to help rule out other diseas ...
... body which has many effects, including smooth and coordinated muscle movement. So the disease would cause loss of muscle control. Diagnosis of PD is based primarily on a medical history and thorough neurological examination. Brain scans and/or lab tests may be performed to help rule out other diseas ...
Magnetic stimulation modulate seizures in epileptic
... pentylenetetrazol-induced seizures in rats [18]. By contrast, a small controlled trial found that 1 Hz rTMS produced a non-significant trend toward short-term seizure reduction [19]. Possibly, distinct effects of different rTMS frequencies could explain this difference. The possible mechanisms by wh ...
... pentylenetetrazol-induced seizures in rats [18]. By contrast, a small controlled trial found that 1 Hz rTMS produced a non-significant trend toward short-term seizure reduction [19]. Possibly, distinct effects of different rTMS frequencies could explain this difference. The possible mechanisms by wh ...
Lecture 52-Epilepsy
... mouth and bilateral, rhythmic jerking of muscles. This lasts from a few seconds to several minutes. Seizures are usually self-limiting, followed by drowsiness, confusion or coma for several hours. ...
... mouth and bilateral, rhythmic jerking of muscles. This lasts from a few seconds to several minutes. Seizures are usually self-limiting, followed by drowsiness, confusion or coma for several hours. ...
Neurological Manifestations of Mitochondrial Disease
... Functional IQ was 85 Verbal IQ was 100; Performance IQ was 65. She had a greater than 30 point split on actual and performance verbal and non-verbal testing. ...
... Functional IQ was 85 Verbal IQ was 100; Performance IQ was 65. She had a greater than 30 point split on actual and performance verbal and non-verbal testing. ...
Inhibition and Epilepsy
... Over fifty years of research on GABA functions have made possible to identify several actions that are mediated by this neurotransmitter. Indeed, when expressed in the complexity of the brain function, the role of GABA receptors goes far beyond the original inhibitory role described in early studies ...
... Over fifty years of research on GABA functions have made possible to identify several actions that are mediated by this neurotransmitter. Indeed, when expressed in the complexity of the brain function, the role of GABA receptors goes far beyond the original inhibitory role described in early studies ...
The Generation of Brain Waves
... The second source of electrical activity in neurons occurs at the synapse. This is the junction of the axon of one neuron and the dendrite of the next neuron. As the impulse arrives at the end of the axon of one cell, transmitter substances (chemicals such as acetylcholine) are released into the syn ...
... The second source of electrical activity in neurons occurs at the synapse. This is the junction of the axon of one neuron and the dendrite of the next neuron. As the impulse arrives at the end of the axon of one cell, transmitter substances (chemicals such as acetylcholine) are released into the syn ...
Action Potential revisited When a stimulus reaches threshold level
... The presynaptic neuron releases the enzyme cholinesterase which breaks down acetylcholine, allowing the sodium channels to close, and repolarization to take place. Why is this important to neuron function? ...
... The presynaptic neuron releases the enzyme cholinesterase which breaks down acetylcholine, allowing the sodium channels to close, and repolarization to take place. Why is this important to neuron function? ...
Local Cortical Circuits
... 7 Transmission of Information by Coincidence . . 7.1 The Single Neuron as a Coincidence Detector 7.2 Existence of Chains of Neuronal Sets with Appropriate Connections 7.3 Some Properties of Synfire Chains 8 Organization of Generators of the ECoG 8.1 The Generation of the ECoG 8.2 Population Statist ...
... 7 Transmission of Information by Coincidence . . 7.1 The Single Neuron as a Coincidence Detector 7.2 Existence of Chains of Neuronal Sets with Appropriate Connections 7.3 Some Properties of Synfire Chains 8 Organization of Generators of the ECoG 8.1 The Generation of the ECoG 8.2 Population Statist ...
Neural Oscillators on the Edge: Harnessing Noise to Promote Stability
... Abnormal neural oscillations are implicated in certain disease states, for example repetitive firing of injured axons evoking painful paresthesia, and rhythmic discharges of cortical neurons in patients with epilepsy. In other clinical conditions, the pathological state manifests as a vulnerability ...
... Abnormal neural oscillations are implicated in certain disease states, for example repetitive firing of injured axons evoking painful paresthesia, and rhythmic discharges of cortical neurons in patients with epilepsy. In other clinical conditions, the pathological state manifests as a vulnerability ...
Powerpoint slides
... About -70 mV Selectively allowing certain ions in With stimulation Na+ is allowed in ...
... About -70 mV Selectively allowing certain ions in With stimulation Na+ is allowed in ...
A gene has been identified that is at cause in several forms of
... An epilepsy crisis is caused by sudden, short-lived, excessive activity of a group of neurons. It causes paroxysmal clinical symptoms, such as convulsions. Normally, epilepsy does not alter the cognitive capacities. However, in certain forms known as epileptic encephalopathies, the epileptic compone ...
... An epilepsy crisis is caused by sudden, short-lived, excessive activity of a group of neurons. It causes paroxysmal clinical symptoms, such as convulsions. Normally, epilepsy does not alter the cognitive capacities. However, in certain forms known as epileptic encephalopathies, the epileptic compone ...
Hormone Levels and EEG (Ashanti)
... scalp. The electrical pulses are know as EEG and show an electrical signal caused by the neurones in the brain EEG is useful because the time resolution is very high. As other methods for researching brain activity have time resolution between seconds and minutes, the EEG has a resolution down to su ...
... scalp. The electrical pulses are know as EEG and show an electrical signal caused by the neurones in the brain EEG is useful because the time resolution is very high. As other methods for researching brain activity have time resolution between seconds and minutes, the EEG has a resolution down to su ...
www.translationalneuromodeling.org
... Excitatory and Inhibitory connections a few cubic mm of volume (~10^4-~10^7 neurons) describe large populations of neurons with a handful of parameters (mean-field approximation) ...
... Excitatory and Inhibitory connections a few cubic mm of volume (~10^4-~10^7 neurons) describe large populations of neurons with a handful of parameters (mean-field approximation) ...
What is a Seizure?
... Epilepsy is NOT a form of mental illness, it is a medical condition. People rarely die or have brain damage from a seizure. A person can NOT swallow his/her tongue during a seizure ...
... Epilepsy is NOT a form of mental illness, it is a medical condition. People rarely die or have brain damage from a seizure. A person can NOT swallow his/her tongue during a seizure ...
Slide ()
... Cellular mechanisms of electroencephalogram rhythm generation during sleep. A. The slow oscillation that underlies the slow waves of the EEG in vivo typically occurs during slow-wave sleep and is generated by the massively recurrent excitatory and inhibitory networks of the cerebral cortex. The slow ...
... Cellular mechanisms of electroencephalogram rhythm generation during sleep. A. The slow oscillation that underlies the slow waves of the EEG in vivo typically occurs during slow-wave sleep and is generated by the massively recurrent excitatory and inhibitory networks of the cerebral cortex. The slow ...
Understand why continuous EEG is being requested in certain
... Elective admission for continuous EEG monitoring Nursing’s Role ...
... Elective admission for continuous EEG monitoring Nursing’s Role ...
the ilaeand the flowering of basic research in the early post–war years
... this was reflected in the ILAE congresses and particularly in Epilepsia. The ILAE conference in 1946 in New York included three basic research papers, on cerebral metabolism and metrazol convulsion in the dog, changes in the oxygen tension of the cerebral cortex of the cat in experimentally induced ...
... this was reflected in the ILAE congresses and particularly in Epilepsia. The ILAE conference in 1946 in New York included three basic research papers, on cerebral metabolism and metrazol convulsion in the dog, changes in the oxygen tension of the cerebral cortex of the cat in experimentally induced ...
آلفا با دامنهي زياد
... Third, the electric and magnetic field decrease with the distance from the source. The neocortex is closer to recording sensors. ...
... Third, the electric and magnetic field decrease with the distance from the source. The neocortex is closer to recording sensors. ...
Spike-and-wave

Spike-and-wave is the term that describes a particular pattern of the electroencephalogram (EEG) typically observed during epileptic seizures. A spike-and-wave discharge is a regular, symmetrical, generalized EEG pattern seen particularly during absence epilepsy, also known as ‘petit mal’ epilepsy. The basic mechanisms underlying these patterns are complex and involve part of the cerebral cortex, the thalamocortical network, and intrinsic neuronal mechanisms. The first spike-and-wave pattern was recorded in the early twentieth century by Hans Berger. Many aspects of the pattern are still being researched and discovered, and still many aspects are uncertain. The spike-and-wave pattern is most commonly researched in absence epilepsy, but is common in several epilepsies such as Lennox-Gastaut syndrome (LGS) and Ohtahara syndrome. Anti-epileptic drugs (AEDs) are commonly prescribed to treat epileptic seizures, and new ones are being discovered with less adverse effects. Today, most of the research is focused on the origin of the generalized bilateral spike-and-wave discharge. One proposal suggests that a thalamocortical (TC) loop is involved in the initiation spike-and-wave oscillations. Although there are several theories, the use of animal models has provided new insight on spike-and-wave discharge in humans.