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abstract english
abstract english

... of brain waves. Twin studies showed that the variation between individuals is highly heritable. Yet it is unknown how individual differences relate to cognitive performance or intelligence. There are many different theories on how brain waves could be involved in higher brain functions, however dire ...
L6. Thalamus (László Acsády) All cortical areas receive thalamic
L6. Thalamus (László Acsády) All cortical areas receive thalamic

... All cortical areas receive thalamic inputs and no cortical area is functional without intact thalamocortical connections. The thalamus has multiple functions. It may be thought of as a kind of hub of information. The thalamus is generally believed to act as a relay between different subcortical area ...
Neural transmission
Neural transmission

... Here are the SSRIs approved by the Food and Drug Administration (FDA) specifically to treat depression, with their generic, or chemical, names followed by ...
ppt - Brain Dynamics Laboratory
ppt - Brain Dynamics Laboratory

... delta oscillations depend on the intrinsic properties of thalamic relay cells, cortical slow oscillation depends on network properties) or in combination (e.g., spindles depend on the interaction between thalamic relay and reticular neurons as well as on their intrinsic properties). ...
overview of neural f..
overview of neural f..

... • conditioning produces LTP-like changes in brain. • drugs that block LTP block learning. ...
What are we measuring in EEG and MEG?
What are we measuring in EEG and MEG?

... in the form of voltage changes and magnetic fields, both of which can be measured noninvasively. • Measured voltage changes at the scalp are called the electroencephologram (EEG). • Measured magnetic fields at the scalp are called the magnetoencephologram (MEG). ...
the limbic system
the limbic system

... At an inhibitory synapse: an inhibitory postsynaptic potential (IPSP) {hyperpolarization} results when channels to potassium are opened. At an excitatory synapse: an excitatory postsynaptic potential (EPSP) {depolarization} results when channels to sodium are opened. The postsynaptic cell's membrane ...
Slide 1 - AccessPharmacy
Slide 1 - AccessPharmacy

... Glutamatergic neurotransmission. Glutamic oxaloacetic transaminase (GOT) converts α-ketoglutarate to glutamate in mitochondria. Glutamate also forms from glutamine via mitochondrial glutaminase. Glutamate is transported into vesicles [6] by VGlut1 (or possibly other subtypes) for exocytotic release ...
PETER SOMOGYI University of Oxford, United Kingdom Peter
PETER SOMOGYI University of Oxford, United Kingdom Peter

... diagonal band nuclei (MSDB) innervate the hippocampus and/or related cortical areas and contribute to the coordination of network activity such as theta rhythmicity and high frequency ripple oscillations (SWR). Some of them exclusively innervate local cortical GABAergic interneurons. Individual MSDB ...
(5 points).
(5 points).

... oscillation (name + frequency range): ____________________________ ...
They Come From the Cortex - American Association of Sleep
They Come From the Cortex - American Association of Sleep

... response of the thalamocortical cells on the other hand are associated with EEG activation and neuronal excitability that creates an activated state vs. a sleep state. In conclusion what is it that the EEG shows me? As you know we can determine NREM, REM, and wake. We can also determine normal EEG, ...
physio unit 9 [4-20
physio unit 9 [4-20

... MODULATE sensory signals Decrease signal transmission when input intensity is too great They travel backwards from cortex to thalamus, medulla, and spinal cord Amplifying Divergence Example Characteristic of corticospinal pathway, which controls skeletal muscles Divergence into multiple tracts Occur ...
Neurons, neurotransmitters and other stuff we did last term…
Neurons, neurotransmitters and other stuff we did last term…

... Neurons, neurotransmitters and other stuff we did last term… Psychology 2617 ...
23Neurotransmitter22012-09
23Neurotransmitter22012-09

... to Cl- Ion and cause hyperpolarization (inhibition). • The glycine receptor is primarily found in the ventral part of the spinal cord. • Strychnine is glycine antagonist. ...
L23-Neurotransmitter
L23-Neurotransmitter

... the central nervous system (CNS). GABAergic inhibition is seen at all levels of the CNS, including the hypothalamus, hippocampus, cerebral cortex and cerebellar cortex. As well as the large well-established GABA pathways, GABA interneurones are abundant in the brain, with 50% of the inhibitory synap ...
Geen diatitel
Geen diatitel

... Electrogenesis of cortical field potentials for a net excitatory input to the apical dendritic tree of a typical pyramidal cell. For the case of a net inhibitory input, polarity is reversed and the apical region becomes a source (+). Current flow to and from active fluctuating synaptic knobs on the ...
Presentazione di PowerPoint
Presentazione di PowerPoint

... ionotropic glutamate receptors (NMDA receptors (NMDARs) and AMPA receptors (AMPARs)) and metabotropic glutamate receptors (mGluR1 to mGluR8) on the membranes of both postsynaptic and presynaptic neurons and glial cells. Upon binding, the receptors initiate various responses, including membrane depol ...
BehNeuro11#2 (2) - Biology Courses Server
BehNeuro11#2 (2) - Biology Courses Server

... d) The arcuate N. cells shown above release NPY & AgRP. What roles do the arcuate neurons that contain MSH & CART play (how does their activity influence the PV and lateral hypothalamic areas?). Use a diagram like the one shown above. ...
chapter 43 mechanisms of action of antiepileptic drugs
chapter 43 mechanisms of action of antiepileptic drugs

... more smaller β subunits (3). The ion-conducting pore is contained within the α subunit, as are the elements of the channel that mediate its fundamental physiologic properties including rapid inactivation. There are nine voltage-gated sodium channels, designated Nav1.1 to Nav1.9. Nav1.2 is the predom ...
Metabotropic Neurot
Metabotropic Neurot

... • All 3 classes inhibit L-type voltage sensitive Ca2+ channels • mGluR activation also closes K+ channels, leading to slow repolarization (prolong excitation) HPC and cortex • Opposite effect in cerebellum • Pre-synaptic mGluRs are inhibitory-on both Glutamate and GABA neurons (Ca2+ channel) ...
Introduction to Anatomy
Introduction to Anatomy

... Communication by neurons depends upon two basic properties of their cell membranes: 1. There is an electrical voltage, called the resting membrane potential, across the cell membrane. 2. Their cell membranes contain a variety of ion channels (pores) that may be open or ...
chapter_8_powerpoint_le07
chapter_8_powerpoint_le07

... Web sites • Society for Neuroscience • www.sfn.org ...
AP151 Neurotransmitters
AP151 Neurotransmitters

... • Binding of NT to receptors on post synaptic membrane can cause EPSPs or IPSPs depending on the combination of NT and receptor at any given synapse. ...
A1987K582900002
A1987K582900002

... that two types of stellate neuron, basket and chandelier cells, used GABA as a neurotransmitter. Although I was the sole author of this paper, Vaughn should have been a coauthor because he provided me with essential criticisms to improve the study. However, he encouraged me to author the paper alone ...
Paternal transmission of subcortical band heterotopia through DCX
Paternal transmission of subcortical band heterotopia through DCX

... mutated neurons and the overlying cortex has neurons without the mutated allele [4]. Our patient, despite having the DCX mutation in all of her cells, probably has a mosaic state due to X inactivation in which neurons express either the normal or a mutant DCX copy [3]. In both cases, the mutation re ...
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Spike-and-wave



Spike-and-wave is the term that describes a particular pattern of the electroencephalogram (EEG) typically observed during epileptic seizures. A spike-and-wave discharge is a regular, symmetrical, generalized EEG pattern seen particularly during absence epilepsy, also known as ‘petit mal’ epilepsy. The basic mechanisms underlying these patterns are complex and involve part of the cerebral cortex, the thalamocortical network, and intrinsic neuronal mechanisms. The first spike-and-wave pattern was recorded in the early twentieth century by Hans Berger. Many aspects of the pattern are still being researched and discovered, and still many aspects are uncertain. The spike-and-wave pattern is most commonly researched in absence epilepsy, but is common in several epilepsies such as Lennox-Gastaut syndrome (LGS) and Ohtahara syndrome. Anti-epileptic drugs (AEDs) are commonly prescribed to treat epileptic seizures, and new ones are being discovered with less adverse effects. Today, most of the research is focused on the origin of the generalized bilateral spike-and-wave discharge. One proposal suggests that a thalamocortical (TC) loop is involved in the initiation spike-and-wave oscillations. Although there are several theories, the use of animal models has provided new insight on spike-and-wave discharge in humans.
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