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Olfactory tubercle neurons exhibit slowphasic firing patterns during
Olfactory tubercle neurons exhibit slowphasic firing patterns during

... well as in the rewarding efficacy of intracranial selfstimulation (Fibiger et al., 1987). Concordantly, the DAergic innervation of the OT has been found to be crucial in the development of a conditioned place preference for methylphenidate (Sellings et al., 2006a,b) and manipulations of DA have prov ...
Central mechanisms of osmosensation and systemic osmoregulation
Central mechanisms of osmosensation and systemic osmoregulation

... of a gastric salt load increases the osmolality of blood in the hepatic portal vein within 7 minutes, whereas systemic osmolality remains unchanged for up to 15 minutes56. Osmoreceptors in these areas can therefore detect the osmotic strength of ingested materials and, through afferent connections t ...
Role of the Preoptic-Anterior Hypothalamus in
Role of the Preoptic-Anterior Hypothalamus in

... In the late 1800s and early 1900s, several lesion and stimulation studies identified the rostral hypothalamus as an important neural structure in the regulation of body temperature [1–10]. The compilation of years of lesion studies suggests that no single neural area acts as the center for thermoreg ...
Abstract
Abstract

... that the majority of LDR neurons located in the SNpc studies appears to have been greater, thus allowing inin this study, as in the rat, project to the striatum and hibitory effects to be seen more readily. that most HDR cells in the SNpr give rise to the extrinsic The present findings support the v ...
The role of the hypothalamic dorsomedial nucleus in the central
The role of the hypothalamic dorsomedial nucleus in the central

... hypothalamic area. The distribution of PrRP-containing fibers in the ventral subdivision of the DMH overlapped completely with the area that contained the Fosimmunoreactive neurons. It was shown that essentially all of these PrRP-ir fibers and terminals contained tyrosine-hydroxylase (TH), like PrRP ...
Autonomic Nervous System
Autonomic Nervous System

... • The amygdala & lateral hypothalamus are the conduits for emotion related input • The suprachiasmatic & medial hypothalamic nuclei regulate circadian & homeostatic functions Mathias & Bannister 4th ed ...
Chapter 3—The Brain and Behavior
Chapter 3—The Brain and Behavior

... cortex. The two hemispheres are connected by the corpus callosum. No complex function can be assigned to one single hemisphere or the other. There is interplay between the two hemispheres. ...
Neurotransmitters
Neurotransmitters

... When they have those emotions, the sympathetic system can still release epinephrine because it is a hormone, not a nerve. Epinephrine is made by adrenal glands and circulates in the blood. However, the patient no longer has parasympathetic neurons attached to the heart to counter the effects of epin ...
Neural Networks
Neural Networks

... glia (greek: “glue”) cells in the central nervous tissue of vertebrates. The function of glia is not understood in full detail, but their active role in signal transduction in the brain is probably small. Electrical and chemical synapses allow for excitatory or inhibitory stimulation. They most ofte ...
The Nervous System
The Nervous System

...  IX Glossopharyngeal nerve – sensory for taste; motor fibers to the pharynx  X Vagus nerves – sensory and motor fibers for pharynx, larynx, and viscera ...
Neuropeptidergic Organization of the Suprachiasmatic Nucleus in
Neuropeptidergic Organization of the Suprachiasmatic Nucleus in

... ABSTRACT: The blind mole rat, Spalax, is a subterranean rodent with atrophied, subcutaneous eyes. Whereas most of the visual system is highly degenerated, the retino– hypothalamic pathway in this species has remained intact. Although Spalax is considered to be visually blind, circadian locomotor rhy ...
basal ganglia
basal ganglia

... On striatal medium spiny neurons of origin of the direct pathway. dopamine binds receptors D1-type, while on those of origin of the indirect pathway binds receptors D2-type. Activation of receptor D1-type induces an increase of cAMP, whereas the activation of receptor D2-type produces a decrease of ...
A transcription factor network controls cell migration
A transcription factor network controls cell migration

... exemplified by cell type specification during vertebrate retinal development, where one glial and six neuronal cell types derive from a common group of progenitors (Turner and Cepko, 1987). While numerous genes that govern this process have been uncovered, precise mechanisms that produce different n ...
Morphological Identification of Cell Death in Dorsal Root Ganglion
Morphological Identification of Cell Death in Dorsal Root Ganglion

... peripheral axotomy than motor neurons, probably because they depend more on neurotrophic molecules released by peripheral target organs [15]. Our study showed that direct reconnection of the proximal nerve stump with its distal stump will reduce the sensory neuronal loss from 42% to 23.7%. In the pr ...
Drugs Acting on the Central and Peripheral Nervous
Drugs Acting on the Central and Peripheral Nervous

... Nerve membranes, which are capable of conducting action potentials along the entire membrane, send messages to nearby neurons or to effector cells that may be located inches to feet away via this electrical communication system. Like all cell membranes, nerve membranes have various channels or pores ...
L4- Student Copy Motor Tracts
L4- Student Copy Motor Tracts

... 30% from the premotor areas , and 40% from the somatic sensory areas posterior to the central sulcus. • 3% of the fibres are large myelinated fibres, derived from the large , highly excitable pyramidal Betz cells of MI . These fibers form monosynaptic connections with motor neurons of the spinal cor ...
Lecture #11 Brain and processing
Lecture #11 Brain and processing

... regions of the body  Cortical areas have been mapped out in diagrammatic form  Homunculus provides indication of degree of fine motor control available: – hands, face, and tongue, which are capable of varied and complex movements, appear very large, while trunk is relatively small – these proporti ...
Nerve Pathways: Functions, Lesions and Adhesions D.Robbins
Nerve Pathways: Functions, Lesions and Adhesions D.Robbins

... discriminative touch, kinesthesia) requires a specific ascending spinal pathway to the contralateral thalamus which, in turn, sends an axonal projection to the cerebral cortex. Generally there are three neurons in the conscious pathway and the axon of the projection neuron decussates and joins a con ...
9.01 Introduction to Neuroscience MIT OpenCourseWare Fall 2007
9.01 Introduction to Neuroscience MIT OpenCourseWare Fall 2007

... • They are also called “stretch receptors,” ...
Electrical Control of Behavior: The Nervous System
Electrical Control of Behavior: The Nervous System

... Not only do neural signals travel via electrical charges within a neuron, but they also travel via chemical transmission between the neurons. Neurons are separated by junction areas known as synapses, areas where the terminal buttons at the end of the axon of one neuron nearly, but don’t quite, touc ...
septins were depleted Orai1 became sites. However, more work will be
septins were depleted Orai1 became sites. However, more work will be

... and Quan Yuan2,* Animals utilize an impressive array of strategies for coping with stressful environmental conditions. If food is in short supply, some suppress their metabolism and hibernate, while others migrate in search of new habitat. These physiological and behavioral adjustments are generally ...
LESSON 4.3 WORKBOOK What makes us go to sleep, and what
LESSON 4.3 WORKBOOK What makes us go to sleep, and what

... to retrieve and think about memories, and to engage in the variety of behaviors that we have to do during the day. The level of brain activity is largely controlled by the arousal neurons located in our brainstem (Figure 12). A high level of activity of these neurons keeps us awake, and a low level ...
Unit 22.1: The Nervous System
Unit 22.1: The Nervous System

... There are several different types of problems that can affect the nervous system. • Vascular disorders involve problems with blood flow. For example, a stroke occurs when a blood clot blocks blood flow to part of the brain. Brain cells die quickly if their oxygen supply is cut off. This may cause pa ...
Nervous System
Nervous System

... – Includes nerves that carry sensory information from receptors to the CNS and nerves that carry motor responses back to periphery – Many actions are reflex activities – Reflex • A programmed response to a stimulus that is automatic • Can be conscious or unconscious but not mentally willed • Protect ...
Laboratory 7: Medulla
Laboratory 7: Medulla

... huge fiber tracts that connect two large regions of the CNS (there are two sets of peduncles, cerebellar and cerebral). A lemniscus is a second-order, decussated axon tract whereas a peduncle is simply a huge, mixed-order, mixed-information bundle. The auditory vestibulocochlear nerve carries both ...
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Circumventricular organs

Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified into (a) sensory and (b) secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the vascular organ of lamina terminalis. They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary, the pineal gland, the median eminence and the intermediate lobe of the pituitary gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.
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