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ARIEL LEVINE Postdoctoral Associate, The Salk Institute for
ARIEL LEVINE Postdoctoral Associate, The Salk Institute for

... Ariel Levine is an MD/PhD postdoctoral associate in the laboratory of Dr. Samuel Pfaff at the Salk Institute, studying how the central nervous system controls movement. In particular, I am working to uncover how the neurons of the spinal cord receive motor commands from the brain and sensory systems ...
BN20 cortical motor control
BN20 cortical motor control

...  Neuron most active  Preferred direction  but active at 45 from preferred  How is direction determined?  Populations of M1 neurons  Net activity of neurons with different preferred directions  vectors ~ ...
Re-examining the debate about the functional role of motor cortex
Re-examining the debate about the functional role of motor cortex

... emerge artifactually, and in predictable patterns, from the biomechanical properties of the periphery. Peter Strick has colorfully referred to this controversy as a "muscles vs. movements" debate. Through a series of experimental and theoretical studies, my colleagues and I re-examine this debate in ...
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Premovement neuronal activity

Premovement neuronal activity in neurophysiological literature refers to neuronal modulations that alter the rate at which neurons fire before a subject produces movement. Through experimentation with multiple animals, predominantly monkeys, it has been shown that several regions of the brain are particularly active and involved in initiation and preparation of movement. Two specific membrane potentials, the bereitschaftspotential, or the BP, and contingent negative variation, or the CNV, play a pivotal role in premovement neuronal activity. Both have been shown to be directly involved in planning and initiating movement. Multiple factors are involved with premovement neuronal activity including motor preparation, inhibition of motor response, programming of the target of movement, closed-looped and open-looped tasks, instructed delay periods, short-lead and long-lead changes, and mirror motor neurons.
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