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Andrea Kádár
Andrea Kádár

... Thyroid hormones regulate the TRH synthesis of hypophysiotropic neurons by negative feedback regulation. OATP1C1, the predominant thyroid hormone transporter molecule through the BBB is highly specific for thyroxine (T4), but not for triiodithyronine (T3), the active form of thyroid hormones. Theref ...
String Art: Axon Tracts in the Spinal Cord Spinal reflex arcs
String Art: Axon Tracts in the Spinal Cord Spinal reflex arcs

PDF version - Richard Andersen
PDF version - Richard Andersen

... and S. These basic phases are common to neurons of both areas range was similar to that of LIP, typically the LS latencies were LIP and 7a. In each phase (LS, M, and S), individual neurons may or may not be active. Most LIP neurons, however, are active in longer (median 160 ms). 12. In summary, area ...
the brain`s concepts: the role of the sensory
the brain`s concepts: the role of the sensory

... 1984). Knowledge is therefore represented in amodal symbolic form. Meaning is referential, in that it derives from a posited correspondence between the system of abstract symbols and their corresponding extensions, the objects and events in the world. Thus, following the line of arguments of early c ...
the brain`s concepts: the role of the sensory
the brain`s concepts: the role of the sensory

... 1984). Knowledge is therefore represented in amodal symbolic form. Meaning is referential, in that it derives from a posited correspondence between the system of abstract symbols and their corresponding extensions, the objects and events in the world. Thus, following the line of arguments of early c ...
The importance of mixed selectivity in complex
The importance of mixed selectivity in complex

... With high dimensionality, information about all task-relevant aspects and their combinations is linearly classifiable(by readout neurons). Nonlinear mixed selectivity neurons are important for the generation of correct behavioral responses, even though pure/mixed selectivity can represent all task-r ...
Selectivity for the Shape, Size, and Orientation of Objects for
Selectivity for the Shape, Size, and Orientation of Objects for

... orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intraparietal area (area AIP) while the animal was grasping or fixating ...
6-Cerebellum 2009
6-Cerebellum 2009

... Purkinje cells are the main output neurons of the cerebellar cortex & project to the deep nuclei of the cerebellum. They are inhibitory to the DCN . The deep cerebellar nuclei ( DCN ) project out to brainstem and thalamic targets via the superior cerebellar peduncles. They are excitatory , but in tu ...
Hypothalamus
Hypothalamus

... preoptic area. The neurochemical phenotype of parvocellular neurons plays an extremely important role in determining the secretory responses of the anterior pituitary gland. Often, two neurochemically distinct populations of parvocellular neurons will have opposing effects upon the same group of cell ...
A mathematical model on REM-NREM cycle
A mathematical model on REM-NREM cycle

... • sleep-wake homeostasis, or Process S, the accumulation of hypnogenic (sleep-inducing) substances in the brain, which generates a homeostatic sleep drive. Both of these processes are influenced to some extent by the genes of the individual. In addition, various external factors can also have a dire ...
The evolution of nervous system centralization
The evolution of nervous system centralization

... tissue that comprises distinct agglomerations of functionally specialized neurons (nuclei) interconnected * Author for correspondence ([email protected]). One contribution of 17 to a Discussion Meeting Issue ‘Evolution of the animals: a Linnean tercentenary celebration’. ...
Neurogenesis
Neurogenesis

... Support for Adult Neurogenesis o3H- Thymidine Autoradiography o Technique used to identify proliferating cells ...
Circuit Architecture of VTA Dopamine Neurons Revealed by
Circuit Architecture of VTA Dopamine Neurons Revealed by

... been comparatively evaluated at the whole-brain level. VTA-DA and VTA-GABA neurons have distinct firing patterns in vivo (Cohen et al., 2012), and their optogenetic activation produces opposing behavioral effects (Tsai et al., 2009; Tan et al., 2012). Thus, a systematic, comparative analysis of syna ...
The rhinal cortices: a wall of inhibition between the
The rhinal cortices: a wall of inhibition between the

... The failure to detect propagation of neuronal activity across the rhinal fissure with laminar field potential analysis could be due to technical limitations, since this method does not reveal evoked activity unless it is laminarly segregated. However, two additional lines of evidence suggest that pr ...
neuron
neuron

... • Na+/K+ pumps pump out 3 Na+ for every 2 K+ they bring in – work continuously to compensate for Na+ and K+ leakage, and requires great deal of ATP • 70% of the energy requirement of the nervous ...
Synaptic Integration in Rat Frontal Cortex Shaped by Network Activity
Synaptic Integration in Rat Frontal Cortex Shaped by Network Activity

... activity affects the neurons’ integrative properties and what function this may imply at the network level remain largely unknown. Most of our knowledge regarding synaptic communication and integration is based on recordings in vitro, where network activity is strongly diminished or even absent. Her ...
Rostral Fastigial Nucleus Activity in the Alert Monkey During Three
Rostral Fastigial Nucleus Activity in the Alert Monkey During Three

... in rostral FN exhibit no activity related to individual eye movements, but respond to vestibular stimulation (Büttner et al. 1991; Gardner and Fuchs 1975). Most studies of the vestibular signals in FN have concentrated on stimulation in the horizontal plane around the Zaxis (yaw stimulation). Under ...
Spinal Cord Review
Spinal Cord Review

... system, 2) awareness of the position and status of muscles and joints by conscious proprioception and 3) visual input regarding our position. Closing the eyes has only slight effect on the normal individual's stance since the vestibular and conscious proprioception systems are sufficient. In a patie ...
The primate basal ganglia: parallel and integrative networks
The primate basal ganglia: parallel and integrative networks

... Frontal cortex is the main driving force of the BG as indicated by its massive topographically and functionally organized pathways. Together they control the ability to carry all aspects of goal directed behaviors including the motivation and cognition that drives and organizes them, along with thei ...
OLED_Optogenetics_abstract_v3_wo_links
OLED_Optogenetics_abstract_v3_wo_links

... causes a visible contraction and immobilization of the larva [10,11]. OK371-GAL4/UAS-H134R-ChR2 flies were raised on solid cornmeal-based medium supplemented with 1mM all-trans-retinal. We mounted the OLED underneath an upright microscope (Nikon Eclipse Ni) with 4x/0.13 NA objective and studied the ...
Comparison of the Distributions of lpsilaterally and Contralaterally
Comparison of the Distributions of lpsilaterally and Contralaterally

... or, at least, very similar. For example, at the cat area 17/i 8 border, layer Ill contains neurons which project ipsilaterally to area PMLS, as well as neurons projecting contralaterally to the area 17/l 8 border region or to area PMLS. In light of the existing data for interconnections between the ...
5104-c2
5104-c2

... • In the suprachiasmatic nucleus (SCN), the master circadian pacemaker, neurons show circadian variations in firing frequency. There is also considerable synchrony of spiking across SCN neurons on a scale of milliseconds, but the mechanisms are poorly understood. • Using paired whole-cell recordings ...
Why are brain pathways
Why are brain pathways

... A neuron in the motor cortex of of an awake behaving monkey fires in relation to the direction of the movement (see “tuning” curve - left). ...
Respiratory 4 Control of Respiration Control of Respiration
Respiratory 4 Control of Respiration Control of Respiration

... a group of neurons in the medulla oblongata region of the brain – Medullary respiratory centre – These neurons drive the activity of the motor neurons that control muscle contraction – Increase motor neuron activity = increase ventilation ...
Article PDF
Article PDF

... from Charles Rivers Laboratories (Wilmington, M A). Pregnancies were timed from the day after breeding (E0). Birth usually occurred on E21. Surgical procedures and injection of the retroviral supernatant into the lateral ventricles of the fetal rat brains are described in detail elsewhere (Walsh and ...
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Premovement neuronal activity

Premovement neuronal activity in neurophysiological literature refers to neuronal modulations that alter the rate at which neurons fire before a subject produces movement. Through experimentation with multiple animals, predominantly monkeys, it has been shown that several regions of the brain are particularly active and involved in initiation and preparation of movement. Two specific membrane potentials, the bereitschaftspotential, or the BP, and contingent negative variation, or the CNV, play a pivotal role in premovement neuronal activity. Both have been shown to be directly involved in planning and initiating movement. Multiple factors are involved with premovement neuronal activity including motor preparation, inhibition of motor response, programming of the target of movement, closed-looped and open-looped tasks, instructed delay periods, short-lead and long-lead changes, and mirror motor neurons.
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