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chapter7
chapter7

... • Gibson believed affordances of objects are made up of information that indicates what an object is used for. – They indicate “potential for action” as part of our perception. – People with certain types of brain damage show that even though they may not be able to name objects, they can still desc ...
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A comparative study of the mammalian amygdala

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cms/lib/NY01001456/Centricity/Domain/535/nervous system tea
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You submitted this quiz on Tue 6 May 2014 6:55 PM CDT. You got a

... Inorrect0.00 Gut mobility requires peripheral autonomic ganglion neurons, which could be impaired by the new toxin. Total ...
Muscle representation in the macaque motor cortex: An anatomical
Muscle representation in the macaque motor cortex: An anatomical

... that innervated ADP motoneurons formed a single dense cluster. However, even this dense cluster measured 2.5 ⫻ 1.1 mm. We noted two interesting disparities between the location of CM cells that innervate digit motoneurons and the types of movements that have been evoked in prior mapping studies of M ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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