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New Autism Research
New Autism Research

... Seeing is doing - at least it is when mirror neurons are working normally. But in autistic individuals, say researchers from the University of California, San Diego, the brain circuits that enable people to perceive and understand the actions of others do not behave in the usual way. According to th ...
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The neuronal structure of the globus pallidus in the rabbit — Nissl
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To allow an immediate response to stimuli in the

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Neuroscience - Thermo Fisher Scientific

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Chapter 8 - Cloudfront.net
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Widzenie - Home - Faculty of Physics University of Warsaw
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31.1 The Neuron Functions of the Nervous System and external

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Module_3vs9_Final - Doral Academy Preparatory

... – Stimulus (tack or nail) – Skin has sensors that pick up mechanical pressure and transform it into electrical signals – Signals are sent by the neuron’s axon to various areas in the spinal cord and brain – Brain interprets electrical signals as “pain” • axon membrane has chemical gates that can ope ...
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General Neurophysiology - Univerzita Karlova v Praze
General Neurophysiology - Univerzita Karlova v Praze

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Lecture 16 Topographic mapping Retinotopic mapping Frog optic

... physical world ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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