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The dynamics of visual responses in the primary visual cortex
The dynamics of visual responses in the primary visual cortex

... causes significant sharpening of orientation selectivity of V1 neurons compared to their feedforward LGN input. The mechanism of sharpening of orientation tuning is, as in the Troyer et al. (1998) model, broadly tuned inhibition. The big difference between this model and that of Troyer et al. (1998) ...
Abstract The cochiear nucleus of the barn owl is composed of two
Abstract The cochiear nucleus of the barn owl is composed of two

... increasing frequency. We have observed this phenomenon both with spike detectors which measure the time of occurrence of the action potential peak and the time at which a fixed voltage level is crossed. Tests with artificial spikes and mathematical simulations show that peak time detection is much l ...
Negative BOLD in Sensory Cortices During
Negative BOLD in Sensory Cortices During

... retrieve an event or a visual image from memory. However the brain mechanisms behind this phenomenon remain poorly understood. Recently, we showed that during visual mental imagery, auditory areas show a much more robust deactivation than during visual perception. Here we ask whether this is a speci ...
Endogenous adult neural stem cells: Limits and potential to repair
Endogenous adult neural stem cells: Limits and potential to repair

... differentiation. In the multifocal model of EAE, cells are not exclusively recruited in the corpus callosum but are also found in the striatum. However, their mobilization seems to be restricted to the regions in the vicinity of the SVZ and RMS. Some of the SVZ cells undergo oligodendrogenesis after ...
Dissecting differential gene expression within the circadian neuronal
Dissecting differential gene expression within the circadian neuronal

... collected for this group, genes that are not expressed in adult clock neurons may be in this category. Genes that are also expressed in adult Figure 4  Fer2 expression is required for behavioral circadian rhythms. (a) Fer2 gene locus. PBac{RB}Fer2 has a P-element insertion ~100 nucleotides upstream ...
Internal structure of spinal cord
Internal structure of spinal cord

... – has long-dendrite tract cells similar to IV; and many various interneurons – afferent fibers = some dorsal root afferent; and especially. descending corticospinal fibers (their major target) – Tracts cells from Lamina IV, V, and VI are generally referred as nucleus proprius – Lamina 5 and 6 receiv ...
Chapter 2: Psychology As a Science
Chapter 2: Psychology As a Science

... postsynaptic neurons that occur when a neurotransmitter binds to one of its receptors. The electrical response of the postsynaptic cell is determined by the receptor.  Depolarized regions of postsynaptic membranes have been stimulated by excitatory neurochemicals to open their ion channels and incr ...
What is Motor Neuron
What is Motor Neuron

... neuron involvement. However, most patients who initially have only upper motor neuron signs eventually develop lower motor neuron signs and go to have ALS. Thus, to be certain that a patient has PLS they must be followed for 3-4 years to be certain that lower motor neuron signs do not develop. PLS h ...
LEVELS OF ORGANIZATION
LEVELS OF ORGANIZATION

... levels immediately after exercise stops? These are all typical questions a physiologist would pose. Finding the answer to them highlights the other characteristic of physiology: it is a mechanistic science. Physiologists ask “how” something occurs, and try to explain the mechanism behind various eve ...
Dementia - Vanderbilt University
Dementia - Vanderbilt University

... Diagnosis and Classification of Dementias • Generally a person is not diagnosed with dementia unless they show difficulties in at least 2 domains and the impairment interferes with daily activities • Dementias can be classified by many different characteristics into “classes”; positive diagnosis wi ...
control of body movement
control of body movement

... Most input from descending pathways goes to interneurons that then synapse with motor neurons. There are 2 general types of interneurons: i) local interneurons, that are confined to the general region of the motor neuron they regulate, ii) intersegmental interneurons, that extend along the spinal co ...
PTA 106 Unit 1 Lecture 1B Structural and Functional areas of the
PTA 106 Unit 1 Lecture 1B Structural and Functional areas of the

... linked to both fear responses and pleasure. Is responsible for determining what memories are stored and where the memories are stored in the brain. It is thought that this determination is based on how huge an emotional response an event invokes. Believed to act as an interface between limibic syste ...
Loss of Notch Activity in the Developing Central Nervous System
Loss of Notch Activity in the Developing Central Nervous System

... in Foxg1Cre;N1 cKOs is mixed. There are caspase-3/nestin double-positive cells as well as caspase-3-positive/nestin-negative cells. However, there appear to be more differentiating neurons dying than neural progenitors since the majority of apoptotic cells are located within the field of Tuj1-positiv ...
Normalization as a canonical neural computation
Normalization as a canonical neural computation

... A third kind of computation has been seen to operate in various neural systems: divisive normalization. Normalization computes a ratio between the response of an individual neuron and the summed activity of a pool of neurons. Normalization was proposed in the early 1990s to explain non-linear proper ...
DESCENDING TRACTS
DESCENDING TRACTS

...  Regulate muscle tone and muscle force.  May be involved in selecting and inhibiting specific motor synergies. ...
Activity 3 - Classical Conditioning
Activity 3 - Classical Conditioning

... Conducting the activity As with many of the uses of the GSR2, we have to bear in mind the ethical implications of the task, in this case exposure the loud noises with the intention of conditioning a fear response. This protocol is within the bounds of day-to-day experience as the stimulus used is co ...
Minireview - Leslie Vosshall
Minireview - Leslie Vosshall

... these glomeruli, DA1, was shown to receive projections from olfactory neurons expressing Or67d, the cVA receptor (Kurtovic et al., 2007). These glomeruli are also the only three glomeruli that receive significant innervation from neurons expressing fruitless (fru), a putative zinc finger transcripti ...
D. What Causes Multiple Sclerosis?
D. What Causes Multiple Sclerosis?

... system (CNS). The CNS consists of the brain, spinal cord, and the optic nerves. Surrounding and protecting the nerve fibers of the CNS is a fatty tissue called myelin, which helps nerve fibers conduct electrical impulses. Multiple sclerosis was first recognized as a disorder in the late nineteenth c ...
CHAP 17c - Dr. Gerry Cronin
CHAP 17c - Dr. Gerry Cronin

... membrane which covers part of the front of the eye – Conjunctivitis is caused most frequently by viral infections (pink eye) and allergy. It can also result from bacterial infections and many other irritants ...
Neurotransmitters
Neurotransmitters

... • Sometimes there is a decrease in the number of receptors for a neurotransmitter on the postsynaptic neuron due to long-term exposure to the neurotransmitter. This is called downregulation. • Neurotransmitters can be classified into 4 major groups: 1. Amino acids (eg, glutamate, gamma-aminobutyric ...
Comparison of Quantities: Core and Format
Comparison of Quantities: Core and Format

... With respect to the processing of symbolic stimuli, we distinguished between the symbolic representation of positive (e.g., 3) and negative integers (e.g., –3). The latter were introduced as a more abstract level of numerical conceptualization. Even though negative integers have not attracted as muc ...
Autonomic Nervous System (ANS)
Autonomic Nervous System (ANS)

... A. Organization of Autonomic nervous system output Sympathetic nervous system: Has an intense ramification ‫(تشعب‬1:20), very diffuse, generalize action Catabolic in nature (expenditure in nature) Para-Sympathetic nervous system: Has an limited ramification (1:1), discrete‫ منفصل‬discharge ,  ...
Target-specific differences in somatodendritic morphology of layer V
Target-specific differences in somatodendritic morphology of layer V

... Dendritic geometry has been shown to be a critical determinant of information processing and neuronal computation. However, it is not known whether cortical projection neurons that target different subcortical nuclei have distinct dendritic morphologies. In this study, fast blue retrograde tracing i ...
Parkinson`s Disease Glossary A guide to the scientific language of
Parkinson`s Disease Glossary A guide to the scientific language of

... becomes manifest when two copies of a mutated gene (two alleles) are present. In order for a particular trait to be expressed, both parents must have the particular mutated allele or gene, and both must pass it to the offspring who then manifests the genetic disease. Some genetic forms of PD are aut ...
Cholinergic induction of network oscillations at 40 Hz in the
Cholinergic induction of network oscillations at 40 Hz in the

... Acetylcholine is vital for cognitive functions of the brain. Although its actions in the individual cell are known in some detail1, its effects at the network level are poorly understood2. The hippocampus, which receives a major cholinergic input from the medial septum/diagonal band3, is important i ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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