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Section 1: Anatomy of the sensorimotor system
Section 1: Anatomy of the sensorimotor system

... There is currently controversy over exactly how many cortical motor areas exist. This is further confounded by disagreement over what criteria should be used to define a motor area. Proposed criteria include requirements that a motor area has projections to spinal motor neurons and a full representa ...
nerve impulse patterns and reflex control in the motor system
nerve impulse patterns and reflex control in the motor system

... At the two extreme levels of activity the histograms are typical of single-unit behaviour, but the bimodal interval distribution for the medium level, with the minimum value at 13 msec, between the modes, is unexpected. The bimodality could arise simply because a small number of records contained lo ...
A Brain Adaptation View of Plasticity: Is Synaptic Plasticity An Overly
A Brain Adaptation View of Plasticity: Is Synaptic Plasticity An Overly

... wild animals have for years confirmed that feral animal brains are larger than those of domestically reared animals (old german and other literature). Nevertheless, studying different degrees of environmental complexity can provide information about brain responses that are likely to generalize to h ...
Mirror Neurons and Mirror Systems in Monkeys and Humans
Mirror Neurons and Mirror Systems in Monkeys and Humans

... Although single mirror neurons code the motor act that is going on in front of the observer, there is recent evidence that, thanks to the functional organization of the parietal and premotor mirror neurons, the observer is also able to understand why that motor act is done, in other terms, the goal ...
Stem cell-based cellular replacement strategies following traumatic
Stem cell-based cellular replacement strategies following traumatic

... The NTera2 (NT2) cell line is a human derived teratocarcinoma cell line that terminally differentiates into postmitotic neuronal NT2N cells when treated in vitro with retinoic acid (36). Grafting of predifferentiated NT2N cells into the periinjured brains of immunocompetent rats following lateral fl ...
Two Kinds of Reverse Inference in Cognitive Neuroscience
Two Kinds of Reverse Inference in Cognitive Neuroscience

... the same type of basic-level motor act. The neural data collected in these studies was obtained using single-cell recordings of macaques (Rizzolatti et al. 2009; Kilner and Lemon 2013), yet fMRI studies suggest that the basic findings 3 The details of the simulation process can be spelled out in var ...
Lecta5 - University of Waterloo
Lecta5 - University of Waterloo

... NOTICE: These materials are subject to Canadian copyright and are presented here as images published in journals and books for which the University of Waterloo holds a licensed electronic subscription. These materials are provided to HLTH 340 students for their exclusive use though a non-public cour ...
the brainstem control of saccadic eye movements
the brainstem control of saccadic eye movements

... the speed and direction of full-field image motion across the retina initiate optokinetic reflexes that supplement the VOR in the low-frequency range. ...
NMDA Receptors Contribute to Primary Visceral Afferent
NMDA Receptors Contribute to Primary Visceral Afferent

... synaptic transmission in the NTS may be due to true differences in the glutamate receptor subtypes activated in these different autonomic reflex pathways or to limitations of the microinjection technique, which typically relies on relatively large volumes (10–100 nl) of highly concentrated agents th ...
In Vitro, Ex Vivo and In Vivo Techniques to Study Neuronal Migration
In Vitro, Ex Vivo and In Vivo Techniques to Study Neuronal Migration

... nucleus predominantly found in the VZ, a short apical process that connects them with the lateral ventricles and a very long basal filament that contacts the outer brain surface. This array of basal radial glia filaments is what newborn neurons use to support and direct their migration towards the o ...
Saccade Target Selection in Frontal Eye Field of Macaque. I. Visual
Saccade Target Selection in Frontal Eye Field of Macaque. I. Visual

... = 0.626, y = 0.338) signaled the monkey to either execute (go) or withhold (nogo) a saccade, respectively. We refer to this color change as the trigger signal. The fraction of nogo trials in a set of blocks was 0% (all go trials), 100% (all nogo trials) or 12%. The time of the trigger signal could b ...
Midbrain fMRI: Applications, Limitations and Challenges
Midbrain fMRI: Applications, Limitations and Challenges

... of one coherent dopaminergic cell complex (e.g. Beckstead et al. 1979; but also see McRitchie et al. (1996) for subtle differences in cell orientation, size and density between these cell groups). Further DA neurons are located in nearby regions such as the hypothalamus, periaqueductal grey, rostral ...
Article - Perelman School of Medicine at the University of
Article - Perelman School of Medicine at the University of

... subcerebral projection neurons in this layer (Arlotta et al., 2005) (Figures 1G, 1H, and 1J–J00 ). Each subtype of CFu neurons, therefore, has a characteristic combinatorial expression of the transcription factors SOX5, CTIP2, and TBR1: (1) SP neurons express an intermediate level of SOX5, a high le ...
Layer 4 in Primary Visual Cortex
Layer 4 in Primary Visual Cortex

... In mammalian primary visual cortex (V1), layer 4 is the major input layer. It receives direct thalamocortical inputs, performs some of the earliest cortical computations and provides the main entrance of sensory information to the cortex. The first part of the current project investigated the respon ...
Long-term channelrhodopsin-2 (ChR2) expression
Long-term channelrhodopsin-2 (ChR2) expression

... Optogenetics tools including channelrhodopsin-2 (ChR2) provide a powerful approach to assay and manipulate neural circuit function, and promise new therapeutic interventions for neurological disease (Zhang et al., 2007; Bernstein and Boyden, 2011; Fenno et al., 2011). A critical prerequisite of opto ...
Document
Document

... • A motor unit consists of a motor neuron and all the muscle fibers it innervates • Three types of motor units (muscles): • Fast fatigable (FF) Powerful, but fatigue with repetitive stimulation muscle fiber: thick, large, white (anaerobic, use glycolytic pathway to generate ATP) Motor neuron large, ...
Thinking About Thinking
Thinking About Thinking

... What matters most here is the process of thinking. By the end of this book, I hope to have shown what neuroscientists think this process entails, that is, how thoughts are generated and sustained, and how well thoughts govern not only bodily action but also mentalistic processes such as beliefs, ide ...
Axon - Cloudfront.net
Axon - Cloudfront.net

... generating and propagating ACTION POTENTIALS (AP).  Only cells with excitable membranes (like muscle cells and neurons) can generate APs. ...
16-1 INTRODUCTION The ANS regulates many important functions
16-1 INTRODUCTION The ANS regulates many important functions

... 4. ALL sympathetic and parasympathetic preganglionic neurons secrete ACh within autonomic ganglia, and ALL sympathetic and parasympathetic postganglionic neurons have nicotinic receptors within the autonomic ganglia. REGULATION OF THE ANS 1. Much of the regulation of ANS function occurs through auto ...
16-1 INTRODUCTION The ANS regulates many important functions
16-1 INTRODUCTION The ANS regulates many important functions

... 4. ALL sympathetic and parasympathetic preganglionic neurons secrete ACh within autonomic ganglia, and ALL sympathetic and parasympathetic postganglionic neurons have nicotinic receptors within the autonomic ganglia. REGULATION OF THE ANS 1. Much of the regulation of ANS function occurs through auto ...
Experiencing Sensation and Perception
Experiencing Sensation and Perception

... Finding the noiciceptor [to glossary], the receptor for pain, has proved particularly difficult over the years. In fact at time it has been proposed that there are not particular receptors that respond to pain ...
Category-specific Conceptual Processing of
Category-specific Conceptual Processing of

... cortical areas engaged in processing semantic meaning of words and concepts. Many researchers agree that temporal cortex provides a unique substrate for semantic binding. Definitions of relevant areas within the temporal lobe range from temporal pole (Hodges, 2001; Rogers et al., 2004) to anterior su ...
Document
Document

... the output layer becomes the winner. This neuron is the only neuron that produces an output signal. The activity of all other neurons is suppressed in the competition.  The lateral feedback connections produce excitatory or inhibitory effects, depending on the distance from the winning neuron. This ...
3- Hopfield networks
3- Hopfield networks

... pattern of activation of various neural regions is observed in the process of recalling an individual. ...
Document
Document

... perceived as being from an area of skin innervated by the same segmental level as the visceral afferent • Results from convergence of somatic & visceral afferents on the same segmental level of the spinal cord • “Cross-talk” in the dorsal horn ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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