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Untitled
Untitled

... hemispheres. This is the corpus callosum. Gently spread apart the cerebellum and the cerebrum. Pick out the pia and blood vessels to expose four rounded mounds, the superior and inferior colliculi (see Figure 7). In sheep, the superior colliculi are much larger and better developed than the inferior ...
reward and reinforcement i
reward and reinforcement i

... The modern concept of motivation derives from the historical desire to account for the needs and drives that govern the strength and direction of our behaviors. The ancient Greeks talked about instincts and hedonism (pleasantness and unpleasantness), and Plato believed that reason was in the head, b ...
View Paper - Dundee Life Sciences
View Paper - Dundee Life Sciences

... Spinal cord cells include motor neurons, sensory neurons and multiple classes of interneuron that together mediate movement and sensation of the body. The molecular mechanisms that specify these different kinds of neuron in the spinal cord have been wellcharacterized (Jessell, 2000; Price and Brisco ...
Slide 1
Slide 1

... nervous system and which receives and sends messages within that system. • Parts of a Neuron – ** Dendrites - branch-like structures that receive messages from other neurons. (the in) – Soma - the cell body of the neuron, responsible for maintaining the life of the cell. – Axon - long tube-like stru ...
Neuronal rebound spiking, resonance frequency and theta
Neuronal rebound spiking, resonance frequency and theta

... bats or mice with knockout of the HCN1 subunit. (a(ii)) Experimental data show the membrane potential of a layer II stellate cell during and after hyperpolarizing steps of different amplitude, showing the depolarizing sag during input, and the depolarizing rebound that generates spikes after input [ ...
Massive Loss of Mid- and Hindbrain Neurons during Embryonic
Massive Loss of Mid- and Hindbrain Neurons during Embryonic

... The failure of Lc/Lc neonates to feed and the cerebellar phenotype of Lc/1 animals suggested that a possible neuronal deficit in homozygous animals may be responsible for their phenotype. To address this possibility, we undertook an in-depth analysis of the Lc/Lc CNS. P0 neonates were genotyped, fix ...
PDF here
PDF here

... The SOD1 mutant mouse is the most widely used model of human amyotrophic lateral sclerosis (ALS). To determine where and when the pathological changes of motor neuron disease begins, we performed a comprehensive spatiotemporal analysis of disease progression in SOD1G93A mice. Quantitative pathologic ...
A Confocal Laser Microscopic Study of Enkephalin
A Confocal Laser Microscopic Study of Enkephalin

... microinjection into the midbrain, or systemically, has no effect on neutral cells. If endogenous enkephalins act within the RVM to produce analgesia by a mechanism analogous to morphine, one would predict that opioid afferents and opioid receptors would be differentially distributed onto RVM on-, of ...
Learning, Reward and Decision-Making
Learning, Reward and Decision-Making

... overly rigid, especially in a volatile environment. Reflexes are perhaps the most primitive form of adaptive response to environmental challenges. Reflexes are stereotyped in that sensory stimuli have innate (unlearned) activating tendencies, which implies that they do not depend on synaptic plastic ...
see p. A4b - Viktor`s Notes for the Neurosurgery Resident
see p. A4b - Viktor`s Notes for the Neurosurgery Resident

... NEUROTRANSMITTER – endogenous chemical agent that relays information from one neuron to another through synapse; released by presynaptic cell (upon excitation), crosses synapse to stimulate or inhibit* postsynaptic cell by binding to receptor. *final result (hyperpolarization or depolarization) is d ...
Postnatal growth and column spacing in cat primary visual cortex
Postnatal growth and column spacing in cat primary visual cortex

... Introduction In the primary visual cortex of the brain, as in other cortical areas, neurons specialized to process particular aspects of the visual input are arranged in complex spatial patterns, called cortical maps, and interact through a dense network of intracortical connections. Recently it was ...
Introduction to Psychology
Introduction to Psychology

... b) Discuss the relationship between methylphenidate use in childhood and drug abuse in adulthood. c) Describe the effects of MDMA on the brain and on behavior. d) Describe the effects of nicotine on the brain. e) Identify three types of opiates and describe their effects on behavior. f) Summarize th ...
Linking Cognitive Neuroscience and Molecular Genetics: New Perspectives from Williams... Ursula Bellugi and Marie St. George (Eds.)
Linking Cognitive Neuroscience and Molecular Genetics: New Perspectives from Williams... Ursula Bellugi and Marie St. George (Eds.)

... prototype neurocognitive disorder for the study of the relationship between genes and behavior via the uncovering of the anatomical structures that intervene. The main idea is that complex behaviors, including cognitive and emotional behaviors, are implemented in large neural systems that are formed ...
Objectives
Objectives

... a) Give a brief overview of the mammalian visual system. b) Describe the phenomenon of lateral inhibition. c) Compare the receptive fields and connections of parvocellular, magnocellular, and koniocellular neurons. ...
Optophysiological analysis of associational circuits in the olfactory
Optophysiological analysis of associational circuits in the olfactory

... of AMPA and NMDA receptor antagonists (CNQX and APV) blocked the inward current to 3.6% (bottom). (D) Results of experiments with various synaptic blockers, with the control responses for each set of experiments set to 100%. PTX refers to picrotoxin. Error bars are SEM. (E) Schematic diagram of the ...
Opposite Effects of Amphetamine Self
Opposite Effects of Amphetamine Self

... MPC and/or OFC function (Jentsch and Taylor, 1999; Rogers et al., 1999; Ornstein et al., 2000). Finally, recent studies in rats have shown that sensitizing regimens of cocaine produce deficits in discrimination/reversal learning (Schoenbaum et al., 2004) and reinforcer devaluation (Setlow and Schoenb ...
Opposite Effects of Amphetamine Self
Opposite Effects of Amphetamine Self

... MPC and/or OFC function (Jentsch and Taylor, 1999; Rogers et al., 1999; Ornstein et al., 2000). Finally, recent studies in rats have shown that sensitizing regimens of cocaine produce deficits in discrimination/reversal learning (Schoenbaum et al., 2004) and reinforcer devaluation (Setlow and Schoenb ...
Autistic-Spectrum-Disorders-Current
Autistic-Spectrum-Disorders-Current

... Nakamoto et al. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proceedings of the National Academy of Sciences of the United States of America. August 2007. ...
The prefrontal cortex encompasses a large and heterogeneous set of
The prefrontal cortex encompasses a large and heterogeneous set of

... of architectonic areas belonging to distinct cortical types, ranging from agranular to eulaminate, have similar features. In addition, we used multidimensional analyses to see if, and how, prefrontal areas form clusters when multiple features are considered simultaneously. We used quantitative unbia ...
Persistent perceptual delay for head movement onset
Persistent perceptual delay for head movement onset

... GVS were significantly slower by 197 to 241 ms compared to the other stimuli. These results were surprising because of the fast transduction latencies of the vestibular afferents. In addition, people do not perceive each of the individual senses separately, as one would expect with such a large disc ...
View/Open
View/Open

... Effect of Removing the Primary Visual Cortex Removal of the primary visual cortex in the human being causes loss of conscious vision, that is, blindness. However, psychological studies demonstrate that such “blind” people can still, at times, react subconsciously to changes in light intensity, to mo ...
Amo, Neuron, 2014
Amo, Neuron, 2014

... activated to negative or aversive emotional events or by situations where the outcome does not match the initial expectation, suggesting a role in transmitting antireward and aversive information (Matsumoto and Hikosaka, 2007, 2009). LHb neurons are connected to GABAergic neurons in the rostromedial ...
introduction
introduction

... neuron is elicited before the first EPSP decays, the two potentials summate and their additive effects are sufficient to induce an action potential in the postsynaptic membrane. • Time constant of the postsynaptic neuron affects the amplitude of the depolarization caused by consecutive EPSPs produce ...
L14- Physiology of T..
L14- Physiology of T..

... form tractus solitarius »»»»» end in the nucleus of tractus solitarius (medulla) From TS cross the midline to ascend in the medial lemniscus to the thalamus ...
PNS: Cranial Nerves
PNS: Cranial Nerves

... PNS: Anatomy of the Parasympathetic Division • Preganglionic neurons originate from the craniosacral regions: • The cranial nerves III, VII, IX, and X • S2 through S4 regions of the spinal cord • Due to site of preganglionic neuron origination, the parasympathetic division is also known as the ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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