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The Nervous System
The Nervous System

... • “All or none” phenomenon…at threshold, all gates will be opened (below threshold, no extra gates will open) and stimulus is transmitted. • Additional Na+ influx causes depolarization of membrane (action potential). • K+ channels remain closed. Cell becomes positive. ...
Vision_notes
Vision_notes

... of photoreceptors have membranous discs with light-sensitive proteins (“visual pigments”) in the disc membranes. Visual pigment includes opsin protein & retinal molecule. Different color sensitivities or rods and of red, green, blue cones are due to different opsin proteins. Rhodopsin=visual pigment ...
Strategies for drug delivery through the blood
Strategies for drug delivery through the blood

... The BBB has several functions • Protects the brain from “foreign substances” in the blood that my injure the brain • Protects the brain from hormones and neurotransmitters in the rest of the body • Maintains a constant environment for the brain ...
Structure of the Brain PowerPoint Notes
Structure of the Brain PowerPoint Notes

... – as the disease progresses, patients develop a shuffling walk and may suddenly freeze in space for minute or hours at a time – It is caused ____________________________ that produce ______________ – ______________ is a medication that boosts the levels of dopamine in the brain – eventually the drug ...
Limbic system
Limbic system

... and sources  Neurons: specialized nerve cells that make up the nervous system and release transmitters ...
File - Biology with Radjewski
File - Biology with Radjewski

... • Signal strength does not change during travel • All or nothing – Positive feedback mechanism to ensure that action potentials always rise to their maximum value ...
C! **D!**E!**F! - Amherst College
C! **D!**E!**F! - Amherst College

... • Before it was understood that nerves signal using electricity, what mode of signalling was attributed to nerves? • What is the earliest experiment (as distinct from observation) cited in Chapter 1? • What are the arguments that experiments on animals such as rats can be relevant to understanding h ...
nervous system
nervous system

... Body: Contains nucleus, control center of the cell.  Regulates production of protein within the cell.  Neurons ...
Neurons - Seung Lab
Neurons - Seung Lab

The eye
The eye

... vision (in penumbra), low acuity, high sensitivity, highly converging i system off connections i • We distinguish scoptopic (rod only), photopic (cone only) and mesopic (both receptors) vision. ...
Enlightenment - The Dartmouth Undergraduate Journal of Science
Enlightenment - The Dartmouth Undergraduate Journal of Science

... the brain from the most basic molecular level up through complex human behavior, and optogenetics holds the most promise for understanding the brain at the intermediate level of neural networks. First, optogenetics can be used to manipulate activity of individual neurons, or small subpopulations of ...
nervous07
nervous07

... Some neurons have many dendrites. Some dendrites have many branches. Ultrastructure similar to cell body. ...
Reuptake, or re-uptake, is the reabsorption of a neurotransmitter by
Reuptake, or re-uptake, is the reabsorption of a neurotransmitter by

Slide ()
Slide ()

... The motor circuit for horizontal saccades. A. Eye velocity component. Long-lead burst neurons relay signals from higher centers to the excitatory burst neurons. The eye velocity component arises from excitatory burst neurons in the paramedian pontine reticular formation that synapse on motor neurons ...
This Week in The Journal - Journal of Neuroscience
This Week in The Journal - Journal of Neuroscience

... A␤1-42 is strongly tied to Alzheimer’s disease (AD), but the critical cellular events leading to loss of synapses and neurodegeneration remain uncertain. To understand how AD pathologydevelopsinamodelsystem,Zhaoetal. overexpressed A␤ isoforms in flight-related motor and interneurons in Drosophila an ...
Electronic Circuits and Architectures for Neuromorphic Computing
Electronic Circuits and Architectures for Neuromorphic Computing

... engineering, examples of neuromorphic circuits, how neural network architectures can be used to build large-scale multi-core neuromorphic processors, and some specific application areas wellsuited for neuromorphic computing technologies. ...
neurohistology
neurohistology

... surface area available for synaptic inputs  In spinal cord, dendritic surface area may be 30 or more times that of cell body ...
Neural Network of C. elegans is a Small
Neural Network of C. elegans is a Small

... • The hermaphrodite version has a simple nervous system comprising about 302 neurons. • It’s neural network is completely mapped. • The pattern of connectivity portrays smallworld network characteristics. ...
Inner Ear
Inner Ear

... stimulate different areas along the basilar membrane and the membrane rubs against hair cells. Each ear contains thousands of hair cells. The hair cells are arranged by frequency (pitch) just like the keyboard of a piano. Nerves are attached to the bottom of these hair cells so when the hair cells m ...
Chapter 6
Chapter 6

... Photoreceptors – rods & cones are first to detect light stimulus Bipolar – generates action potentials Amacrine & Horizontal cells – integrate and regulate input from multiple photoreceptor cells Ganglion cells’ axons converge to form the optic nerve (cranial nerve II) and exit the eye, creating the ...
A crucial role of plasma membrane-associated sialidase (NEU3) for
A crucial role of plasma membrane-associated sialidase (NEU3) for

... from The Cell Bank of Tohoku University, Sendai, Japan, and WI-38 (fetus lung fibroblast) cells from HSRRB, Osaka, Japan. HT-29 (colon adenocarcinoma) cells were from ATCC (Manassas, VA). All were maintained in DMEM supplemented with 10% fetal bovine serum in a humidified atmosphere containing 5% CO ...
nerve net
nerve net

... • The fatty insulation covering produced by the Schwann cells. • Nodes of Ranvier – Area of no myelin ...
Introduction
Introduction

... kind of information. ...
AP Ch. 9 Nervous System Part 1 Worksheets
AP Ch. 9 Nervous System Part 1 Worksheets

... 3. Neurons are composed of a network of fine threads called _________________________________ 4. The nervous system consists of two parts, the brain and spinal cord make up the ______________ nervous system, and the nerves throughout the body make up the ___________ nervous system. 5. ______________ ...
Identification of oculomotor-restricted genes with motor neuron
Identification of oculomotor-restricted genes with motor neuron

... ESC-MNs to express the light-sensitive ion channel, channelrhodopsin-2 (ChR2), so that when we optically stimulate these ESC-MNs with blue light, they can induce finely-controlled contraction of reinnervated muscles Figure 1: The schematic illustrates the transplantation of embryonic stem cellderive ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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