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Neurons
Neurons

... • Provide supportive functions for neurons • Cover nonsynaptic regions of the neurons ...
Neuronal Birthdate-Specific Gene Transfer with Adenoviral Vectors
Neuronal Birthdate-Specific Gene Transfer with Adenoviral Vectors

... Progenitor cells show altered patterns of gene expression over time (Frantz et al., 1994; Burrows et al., 1997). This suggests that the progenitor cells are intrinsically different at each neuronal birthdate. Their intrinsic changes appear to regulate their commitment to specific laminar phenotypes, ...
Neurons in red nucleus and primary motor cortex exhibit similar
Neurons in red nucleus and primary motor cortex exhibit similar

... function (Gribble and Scott, 2002). This method characterizes the ‘‘mass distribution’’ of torque-related activity by assuming that activity changes linearly between sampled torque directions and that torque magnitude is equal for each torque direction. To use this method, the lowest activity across ...
Neuronsderivedfromradialglialcells establish radial units in neocortex
Neuronsderivedfromradialglialcells establish radial units in neocortex

... a small cluster of additional cells (3.7 6 0.52 cells per clone), all in contact with the radial process (Fig. 1B). It is therefore unlikely that we are mistakenly combining separate glial and neuronal clones. To con®rm that clones included both neurons and glia, we used immunolabelling with cell-ty ...
1 The Brain and Behavior
1 The Brain and Behavior

... notion that there was no soul, that all mental processes could be reduced to actions within different regions in the brain! The aggregate-field view was first seriously challenged in the mid-nineteenth century by the British neurologist J. Hughlings Jackson. In his studies of focal epilepsy, a disea ...
Document
Document

... 2. K+ channels open, K+ diffuses outward; Na+ channels are closed and inactivated 3. Membrane returns to resting potential ...
Zn2 Slows Down CaV3.3 Gating Kinetics: Implications for
Zn2 Slows Down CaV3.3 Gating Kinetics: Implications for

Visual and presaccadic activity in area 8Ar of the macaque monkey
Visual and presaccadic activity in area 8Ar of the macaque monkey

... distress or illness included changes in body weight, grooming habits, and water intake, and these ...
On the Role of Biophysical Properties of Cortical Neurons in Binding
On the Role of Biophysical Properties of Cortical Neurons in Binding

SUBARACHNOID HEMORRHAGE
SUBARACHNOID HEMORRHAGE

... was intoxicated at the time of the event is not an uncommon scenario in those cases that come to the medical examiners or coroner’s office. Whether alcohol directly affects vascular wall integrity is not known. However, it has been shown that red wine strongly inhibits the synthesis of endothelin-1, ...
Amo, Neuron, 2014
Amo, Neuron, 2014

... fish stays in the same compartment as the red light cue is presented as the conditioned stimulus (CS) and receives electrical shock as a negative reward (R). During this period, the reward expectation value (V) gradually changes from 0 to R ultimately, and the fish eventually learns to associate t ...
Cerebellum Learning objectives At the end of this lecture, the
Cerebellum Learning objectives At the end of this lecture, the

... Located dorsal to the pons and medulla Makes up 11% of the brain’s mass Cerebellar activity occurs subconsciously Provides precise timing and appropriate patterns of skeletal muscle contraction Programming ballistic movements Acts as comparator for movements Correction of ongoing movements Motor lea ...
basal ganglia
basal ganglia

... Vesalius (Andreas van Wesel, 1514-1564) with a rather accurate view of the basal ganglia. Bundles of white matter (E), corresponding roughly to internal capsule, are shown separating masses of grey matter (D), the lower medial one corresponding to the thalamus and the upper lateral one to the putame ...
Anatomy Lecture 3 Descending Motor Tracts In the last lecture the
Anatomy Lecture 3 Descending Motor Tracts In the last lecture the

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Poster
Poster

... hyperpolarization of the cell. Oguchi disease is caused by mutations in rhodopsin kinase which prevent the phosphorylation of rhodopsin, lowering rhodopsin’s affinity for arrestin. This reduced ability to bind arrestin decreases the speed in which rhodopsin is deactivated and prepped to reactivate. ...
The Neurobiology of Cricket Song
The Neurobiology of Cricket Song

... the cells become physiologically mature and what kind of electrical activity do they exhibit before reaching maturity? When are the functional connections that coordinate activity of the cells es­ tablished? Is the network assembled be­ fore or after the cricket becomes an adult? If it is after, doe ...
Title - HAL
Title - HAL

... al.,1997), we have chosen an approach also dealing with metrical parameters of the three neuronal types. However, not all metrical aspects were taken into account because we did not consider diameter-linked parameters or those characterizing the dendritic spatial occupancy, which has been extensivel ...
Collateral projections from the median raphe nucleus to the medial
Collateral projections from the median raphe nucleus to the medial

... diagonal band nucleus (MS/DBv) and lateral aspects of the lateral septum, while those to the hippocampal formation (HF) predominantly distribute to stratum lacunosum-molecular of Ammon’s horn, and to the granule cell layer and immediately adjacent inner molecular layer of the dentate gyrus (DG). An ...
View Paper - Dundee Life Sciences
View Paper - Dundee Life Sciences

... time gets longer as development proceeds in many neuroepithelia, including the spinal cord (Kauffman, 1968), it has yet to be established whether this is a specific characteristic of all neurongenerating divisions. Here we have developed a novel long-term time-lapse imaging assay to monitor single c ...
Developmental Changes Revealed by Immunohistochemical
Developmental Changes Revealed by Immunohistochemical

... & Department of Molecular & Cell Biology (LSA #3200), University of California, Berkeley, CA 94720-3200, USA interstitial neurons of the adult subcortical white matter (Valverde and Facal-Valverde, 1988; Chun and Shatz, 1989b; Kostovic and Rakic, 1990; Meyer etal, 1992). The subplate is a region thr ...
DOI: 10.1515/aucts-2015-0011 ACTA UIVERSITATIS CIBINIENSIS
DOI: 10.1515/aucts-2015-0011 ACTA UIVERSITATIS CIBINIENSIS

Hypothalamic pathways linking energy balance and reproduction
Hypothalamic pathways linking energy balance and reproduction

... systemic insulin therapy (1, 80). High numbers of IRs are also found on POMC/CART neurons (9). Interestingly, no obvious metabolic or reproductive phenotype was seen in mice lacking IRs only in POMC neurons (59). Although LepRs are expressed in many hypothalamic nuclei (34, 36, 65), significant atte ...
Orexin (Hypocretin)-Like Immunoreactivity in the Cat Hypothalamus
Orexin (Hypocretin)-Like Immunoreactivity in the Cat Hypothalamus

... identified an autosomal recessive mutation in the well-established canine model of narcolepsy; it was reported that this mutation caused the disruption of the OX2R. At the same time, using gene knockout techniques, Chemelli et al.21 found that mice lack- ...
Cortical cfos Expression Reveals Broad Receptive Field Excitatory
Cortical cfos Expression Reveals Broad Receptive Field Excitatory

... somatosensory cortex, distinguished by expression of the activity-dependent fosGFP reporter gene, would be preferentially activated by whisker stimulation. In fact, two-photon targeted, dual whole-cell recordings showed that principal whisker stimulation elicits similar amplitude synaptic responses ...
Stimulus-Dependent Synchronization of Neuronal Responses in the
Stimulus-Dependent Synchronization of Neuronal Responses in the

... preferences for particular features of visual stimuli, but in general, the tuning is broad. Thus, even simple stimuli evoke responses in numerous neurons with differing but overlapping feature preferences, and it is commonly held that a particular feature is encoded in the pattern of graded response ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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