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PPR N P S Medication review for your patients with heart failure
PPR N P S Medication review for your patients with heart failure

... If inadequate doses of diuretics are used when congestion is present, this may diminish the response to ACE inhibitors1. Excessive diuretic doses can increase the risk of hypotension and renal impairment with the ACE inhibitor. Reduce the dose of loop diuretic if necessary (eg low dose frusemide 20- ...
药理概论2
药理概论2

sedation and pain management for routine
sedation and pain management for routine

... Choosing the correct analgesic therapy requires an understanding of both the pharmacokinetics of a  wide range of drugs as well as the levels or type of pain associated with various conditions.  Also, it has  been recognized in human patients that there is great individual variation in responsivenes ...
Featured Guest Speaker
Featured Guest Speaker

... GLYXAMBI tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both empagliflozin and linagliptin is appropriate. GLYXAMBI is not recommended in patients with type 1 diabetes or for the treatment of diabetic k ...
Pharmacologic Debridement: More Does Not Equal Better
Pharmacologic Debridement: More Does Not Equal Better

...  SSRIs  TCAs  Vincristine ...
EPINEPHrine (ep-i-nef-rin) - DavisPlus
EPINEPHrine (ep-i-nef-rin) - DavisPlus

... fused or products incorrectly diluted. Dilutions should be prepared by a pharmacist. IV doses should be expressed in milligrams not ampules, concentration or volume. Prior to administration, have second practitioner independently check original order, dose calculations, concentration, route of admin ...
The Multidisciplinary Team - MDT - West Coast District Health Board
The Multidisciplinary Team - MDT - West Coast District Health Board

... The MDT is comprised of a group of health professional from various disciplines, involved in the direct provision of treatment and treatment planning. The MDT members are drawn from psychiatry, nursing, social work, psychology, and occupational therapy, Maori mental health, alcohol and drug workers ...
National Cutting Horse Association
National Cutting Horse Association

... rhabdomyolysis ("tying up"), endotoxic shock, respiratory disease, eye injuries and diseases, general surgery, laminitis, and other musculoskeletal disorders. Extensive research substantiates the efficacy of flunixin over other NSAIDs in the therapy of endotoxic shock in horses. The recommended dose ...
Document
Document

... severe bradycardia and presence of other diseases. This patient didn’t have previous underlying heart disease, in addition, hyponatremia may not contribute to TdP. But several routine medications have been associated with QTc interval prolongation, including aripiprazole, venlafaxine and famotidine. ...
Liquid Handcuffs”: the bio-politics of methadone
Liquid Handcuffs”: the bio-politics of methadone

... processes: propagation, births and mortality, the level of health, life expectancy and longevity” (1980) • Examples: (1) harm reduction as regulatory biopower?, (2) expansion of treatment access, (3) date collection, (4) addiction research ...
Levosimendan: The Next Dobutamine?
Levosimendan: The Next Dobutamine?

... calcium levels), vasodilation (coronary, systemic, pulmonary), and no effects on myocardial oxygen demand nor arrhythmogenesis. The most common adverse effects are headache and mild hypotension. Clinical research experience has been accumulating with levosimendan. In patients with severe low-output ...
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia

... rituximab is 90 mg/m2 days 1 and 2 based on the data in the relapsed setting.23,24 Rummel et al first reported on 63 patients with relapsed or refractory lymphomas (median age, 63 years)25 with either follicular lymphoma (24), mantle cell (16), immunocytoma (17), or marginal zone lymphoma (6). Benda ...
Psychotropic Drugs and Ocular Side Effects
Psychotropic Drugs and Ocular Side Effects

... woman caused rotation in the anterior chamber angle as a result of uveal effusion and development of acute bilateral ACG. The use of escitalopram was stopped, steroid treatment was started, and the patient showed complete recovery.60 Fluoxetine is the first SSRI correlated with ACG. ACG has develope ...
4-ANS applied pharm(Lec.1,2,3)
4-ANS applied pharm(Lec.1,2,3)

Zydelig - Gilead
Zydelig - Gilead

... Fatal and/or serious hepatotoxicity occurred in 18% of patients treated with Zydelig monotherapy and 11% of patients treated with Zydelig in combination trials. Elevations in ALT or AST greater than 5 times the upper limit of normal have occurred [see Adverse Reactions (6.1)]. These findings were ge ...
Intravenous Milrinone in Cardiac Surgery
Intravenous Milrinone in Cardiac Surgery

... From these 310 articles, the authors identified 42 that were deemed most relevant to cardiac surgery and used them as the basis for this review. An overview of the characteristics of milrinone and evidence of its use in cardiac surgery follows. ...
Tricyclic Antidepressants
Tricyclic Antidepressants

... Readily crosses blood-brain barrier Peak levels occur 2-6 hours post ingestion Decreased gut motility may prolong absorption • Highly protein bound • Tissue levels up to 100 times plasma level • Only 1-2% total-body TCA in plasma ...
clinical trials
clinical trials

... CLINICAL TRIALS The institutional review board, usually made up of physicians, statisticians, community advocates and lay people, examines the study’s protocols to ensure that the patients’ rights are protected and that the study does not present an undue or unnecessary risk to the patients. There ...
alkermes - Moodle Lille 2
alkermes - Moodle Lille 2

... •Combinaison of ALKS 33 and olanzapine (ZYPREXA) designed to have efficacy of olanzapine with attenued weight gain •Olanzapine show to have highest efficacy, but also highest incidence of weight gain among atypical antipsychotics ...
ZUCLOPENTHIXOL tab, drops , amp: Class: Typical antipsychotic
ZUCLOPENTHIXOL tab, drops , amp: Class: Typical antipsychotic

... -Acute psychosis: Initial: 10-50 mg/day in 2-3 divided doses; may titrate dose upward by 10-20 mg every 2-3 days; usual dosage range: 20-60 mg/day; maximum dose: 100 mg/day -Maintenance therapy: Maintain lowest effective dose; usual maintenance dose: 20-40 mg/day; may be given as a single dose -Acut ...
NEW ZEALAND DATA SHEET CLOZARIL® (clozapine) 25mgand
NEW ZEALAND DATA SHEET CLOZARIL® (clozapine) 25mgand

...  with schizophrenia who are non-responsive to or intolerant of classical antipsychotic agents, or with schizophrenia or schizoaffective disorder who are at risk of recurrent suicidal behaviour (see Indications),  who have initially normal leukocyte findings (white blood cell count (WBC) ≥ 3500/mm3 ...
Antiemetic Guidelines for Chemotherapy and Radiation Therapy
Antiemetic Guidelines for Chemotherapy and Radiation Therapy

... regimens and 8% in AC-like regimens. Consensus recommendations from MASCC and ASCO guidelines state: „Following randomized trials Aprepitant has shown a significantly higher rate of protection from acute and delayed emesis when added to a 5HT3 antagonist and dexamethasone for high risk chemotherapy ...
Patient Monitoring and Documentation
Patient Monitoring and Documentation

...  Add up first 24-hour dose requirement.  Give 50% of this dose over the next 24 hours in 4 divided doses i.e. Q6H  Reduce maintenance dose by 25% each day if patient’s symptoms remain controlled.  Continue prn regimen as needed for breakthrough agitation that is presumed due to delirium . ...
Unlicensed Medicines - Neonatal and Paediatric Pharmacists Group
Unlicensed Medicines - Neonatal and Paediatric Pharmacists Group

... of babies in neonatal intensive care of children in paediatric intensive of children in hospital across Europe of children treated at home by their ...
Slide
Slide

... Assessment of the dose response should an integral part of establishing the safety and efficacy of the drug. When available, dose concentration data are useful and should be incorporated into the dose–response analysis. Regulatory agencies and sponsors should be open to new approaches and receptive ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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