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The Nervous System
The Nervous System

... • The spinal cord runs along the dorsal side of the body and links the brain to the rest of the body. Vertebrates have their spinal cords encased in a series of (usually) bony vertebrae that comprise the vertebral column. • The gray matter of the spinal cord consists mostly of cell bodies and dendri ...
Initiation of the arousal response
Initiation of the arousal response

... the paper overall. The systems discussed here seem almost infinitely complex, with most neural circuit responses balanced by some sort of anti-response, in networks where loops of mutual interaction are the rule, so that it is rarely possible to say which processes are definitely upstream or downstr ...
PDF
PDF

... both Vldlr and Apoer2, exhibit identical behavior and neuroanatomy and provide strong evidence for the involvement of these proteins in the same signaling pathway (22). The Reln-positive CR neuron is one of the first neurons to mature during early cortical development. It was initially described in ...
Neurons eat glutamate to stay alive
Neurons eat glutamate to stay alive

... Neurons are thought to primarily rely on glucose to fuel mitochondrial metabolism. In this issue, Divakaruni et al. (2017. J.  Cell Biol. https​://doi​.org​/10​.1083​/jcb​ .201612067) show that neurons are also happy to use glutamate. When neurons use this neurotransmitter, its concentration drops, ...
Human Anatomy Unit 6 – Chapter 8 – Nervous System Work List
Human Anatomy Unit 6 – Chapter 8 – Nervous System Work List

... The Moving Impulse A neuron remains in its resting state until it receives a stimulus large enough to start a nerve impulse. The impulse causes a movement of ions across the cell membrane. An impulse begins when a neuron is stimulated by another neuron or by the environment. Once it begins, the impu ...
Central nervous system
Central nervous system

... has the genetic information and machinery necessary for protein synthesis.  The dendrites are a series of highly branched outgrowths of the cell body. They and the cell body receive most of the inputs from other neurons, the dendrites being more important in this role than the cell body.  The bran ...
Functional Connectivity during Surround Suppression in
Functional Connectivity during Surround Suppression in

... The response of neurons whose receptive fields were overlapping with the stimulus position, was used to assign the 200msec time epoch corresponding to each stimulus presentation into two groups. When the response of the neuron was below its maximum value while the stimulus radius was larger than the ...
Biology 251 Fall 2015 1 TOPIC 7: PERIPHERAL NERVOUS SYSTEM
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... Receptor cells constantly replaced; only neurons known that do this d) 5 million receptors of 1000 different kinds (compared to only 3 receptor types for color vision and 4 for taste) ...
Spinal Cord and Spinal Nerves
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Chapter 8 Nervous System
Chapter 8 Nervous System

... C. Neuroglia (glial cells) – helper cells of the nervous system – do not conduct action potentials – function in support, nourishment, and protection of neurons – capable of mitotic division – is the most common cell in the nervous system – only cell in the nervous system prone to disease (diseases ...
Synaptic pathways and inhibitory gates in the spinal cord dorsal horn
Synaptic pathways and inhibitory gates in the spinal cord dorsal horn

... mozygotic transgenic mice that express EGFP under control of the gad1 gene promoter to identify glutamic acid decarboxylase 67 (GAD67) GABAergic neurons. This results in fluorescent labeling of 30–70% of the GABAergic neurons in the dorsal horn.14–16 Recording from these neurons and stimulating the ...
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3680Lecture13 - U of L Class Index
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temporal visual event recognition
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ppt - UK College of Arts & Sciences
ppt - UK College of Arts & Sciences

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Slayt 1
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Sequencing the connectome. - Cold Spring Harbor Laboratory
Sequencing the connectome. - Cold Spring Harbor Laboratory

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primary somatosensory cortex
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... What are the major areas of the brain that are associated with the perception of touch? (continued) • The majority of thalamic neurons that receive touch information subsequently project the information to the primary somatosensory cortex (SI). Thereafter, information is projected to the secondary ...
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Temporal Sequence Detection with Spiking Neurons: Towards

... active dendrites and dynamic synapses in an integrated model. For a long time, dendrites have been thought to be the structures where complex neuronal computation takes place, but only recently have we begun to understand how they operate. The dendrites do not simply collect and pass synaptic inputs ...
The Brain - Miami Arts Charter School
The Brain - Miami Arts Charter School

... release neurotransmitters into the synapse. The neurotransmitters fit into receptor sites on the dendrites of neuron B. If enough neurotransmitters are received (threshold is achieved), positive ions rush through the now permeable cell membrane of neuron B. This rapid electric message firing is call ...
Perception - U
Perception - U

... Striate-Cortex Organization • Columns of vertical-line-preferring neurons have been visualized by injecting radioactive 2-DG and then moving vertical stripes back and forth in front of the animal for 45 min.; the subjects were then immediately killed and their brains sectioned; columns of radioactiv ...
00216 - UROP
00216 - UROP

... Activation of group I metabotropic glutamate (mGlu) receptors causes the endocannabinoid system to induce both short- and long-term changes in synaptic strength in the striatum, the hippocampus, and other regions of the brain. Although current electrophysiological evidence suggests a role for the re ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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