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Tactile Stimulation
Tactile Stimulation

... Prolonged vibration stimulation to normal individuals could lead to muscle weakness attributable to attenuation of afferent feedback. This weakness is neurophysiologically similar to that seen in patients with knee injury. Theoretically, increasing input to gamma motor neurons could reverse this wea ...
Is Diabetic Nerve Pain Caused by Dysregulated
Is Diabetic Nerve Pain Caused by Dysregulated

... sensitized (become hyperexcitable) by various mechanisms in response to the pathological conditions or peripheral tissue injury associated with diabetes. Multiple pathogenic mechanisms, such as the formation of intracellular advanced glycation end products, inflammatory cytokines, increased aldose re ...
PowerPoint Ch. 6
PowerPoint Ch. 6

... geniculate nucleus of the thalamus; the other areas get some input from the thalamus but most from cortical areas. ...
The Biological Bases of Behaviour
The Biological Bases of Behaviour

... information (except smell) must pass through to get to the cerebral cortex.  It helps to put together the information we gather from our senses. ...
The Biological Basis for Behavior
The Biological Basis for Behavior

... • d. The myelin sheath is a layer of fatty segmented tissue that encases the fibers of many neurons – Enables vastly greater transmission speed of neural impulses as the impulse hops from one node (link) to the next » Degeneration leads to multiple sclerosis • e. The Synapse (synaptic gap)= the jun ...
Unit 3
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... – Vary in response to the same stimulus depending on behavioral task (precision vs. power grip) ...
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... and a descending branch that carry information about crude touch, two point discrimination and vibration. The dorsal column consists of fasciculus gracilis (legs) medially and fasciculus cuneatus (arms) laterally. These fibers end in the medulla, in N.gracilis and N.Cuneatus. Second order neurons se ...
Observational Learning Based on Models of - FORTH-ICS
Observational Learning Based on Models of - FORTH-ICS

... association pathway is also responsible for the action association function. This is accomplished using the SI-SPL-VIP circuitry. SPL, apart from SI, also accepts connections from VIP, i.e. the region encoding a distributed representation of the demonstrator’s active fingers. These synapses (VIP-SPL ...
15. Nervous System: Autonomic Nervous System
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... The parasympathetic division maintains the body during “normal,” non-stressful situations. Your text refers to it as the “resting and digesting system.” It reduces the activities of some organs (e.g., the heart) and generally elevates activity of the digestive system. The sympathetic division genera ...
Dispatch Vision: How to Train Visual Cortex to Predict Reward Time
Dispatch Vision: How to Train Visual Cortex to Predict Reward Time

... issue build on this work to better understand the mechanisms by which V1 neurons can be trained to exhibit such responses. What might be the circuit origin of reward timing activity in V1? Is it a reflection of a ‘cognitive’ brain function that is relayed from other, higher cortical areas, such as ...
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amy-2a-2016-cryders-rmp-and-generation-of-action

... pulls ions back into the cell. K+ ions will continue to diffuse out of the cell until the electrical potential is equal but opposite. Once equilibrium is reached, there will be no net movement of ions. -90mv is the equilibrium potential for K+ and -70mv is the resting membrane potential for a neuro ...
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pain - MEFST
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... •sensory pain fibers innervating the heart follow the sympathetic innervation of this organ back to the spinal cord, and their cell bodies are located in thoracic dorsal root ganglia at T1–T5. •The neuronal cell bodies supplying the dermatomes of the upper thorax and upper limbs are also located in ...
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... detectors”, such as those found in the superior central sulcus in the ventral visual pathway [2]. How the brain creates prediction signals in general relates to the fundamental question of how the brain represents time. Buonomano [4] discussed the two prevalent views of how this may be – “labeled li ...
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Competitive learning
Competitive learning

... The lateral connections are used to create a competition between neurons. The neuron with the largest activation level among all neurons in the output layer becomes the winner. This neuron is the only neuron that produces an output signal. The activity of all other neurons is suppressed in the compe ...
APPLICATION OF AN EXPERT SYSTEM FOR ASSESSMENT OF
APPLICATION OF AN EXPERT SYSTEM FOR ASSESSMENT OF

... The lateral connections are used to create a competition between neurons. The neuron with the largest activation level among all neurons in the output layer becomes the winner. This neuron is the only neuron that produces an output signal. The activity of all other neurons is suppressed in the compe ...
control of movement by the CNS - motor neurons found in anterior
control of movement by the CNS - motor neurons found in anterior

... cells in one column may fire when muscle is active in a specific movement (synergy) same cells may be silent when same muscle participates in a different movement not necessary to represent every possible muscle synergy finite set of cardinal synergies, which can be combined and weighted - coding di ...
Human Cortex: Reflections of Mirror Neurons
Human Cortex: Reflections of Mirror Neurons

... exhibited larger fMRI responses during movement execution than rest. Blue: cortical areas that exhibited larger fMRI responses during movement observation than rest. Note that there is an overlap of both effects in anterior intraparietal sulcus and ventral premotor area, which have been suggested as ...
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Design Overview - Computer Science & Engineering

... Current brain simulators require extraneous methods during the setup process to be fully functional NCS cannot easily be accessed remotely to build models, run simulations, and view output ...
20150210_RAVI_Lecture
20150210_RAVI_Lecture

... ‘Aspects of the conceptual inspiration for optogenetics can be traced to the 1970s. In 1979 Francis Crick, taking note of the complexity of the mammalian brain and the fact that electrodes cannot readily distinguish different cell types (Crick, 1979), suggested that a major challenge facing neurosc ...
Lesson 33 - UBC Zoology
Lesson 33 - UBC Zoology

... Sensory information arriving from the periphery synapses on cell bodies in the dorsal horns of the spinal cord. These are thus, second order neurons and are referred to as interneurons or association neurons. For reflex arcs, they carry the information to motor neuron cell bodies in the ventral horn ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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