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GENE REGULATION
GENE REGULATION

... In eukaryotes, a pre-mRNA transcript is processed before it becomes a mature mRNA When a pre-mRNA has multiple introns and exons, splicing may occur in more than one way Alternative splicing causes mRNAs to contain different patterns of exons. Allows same gene to make different proteins  At ...
Protein Synthesis
Protein Synthesis

... sequence of nucleotides at any point and estimate the length of the polypeptide that can be synthesized before a break in the chain occurs, due to the lack of an appropriate codon and amino acid. Another kind of mutation which can occur is one in which one nucleotide is replaced by a different nucle ...
Homework Assignment #7
Homework Assignment #7

... the top strand are labeled. Use the lines to illustrate a eukaryotic gene that has two introns. Include the following in your drawing: promoter, transcription start site, all exons, both introns, the 5’ and 3’ splice site of the introns, a reasonable location for the ATG start codon and a TAA stop c ...
Visualization of RNA molecules using VMD
Visualization of RNA molecules using VMD

... chain. Later on the chain will become a protein. TRNA consists of 74-93 nucleotides and has sites for codon recognition and amino acid. It belongs to non-coding RNAs. TRNA attaches to the mRNAs codon by hydrogen bond and leaves the right amino acid to its place. ...
Regulation of Gene Expression
Regulation of Gene Expression

... Hundreds of different transcription factors have been discovered; each recognizes and binds with a specific nucleotide sequence in the DNA. A specific combination of transcription factors is necessary to activate a gene. Transcription factors are regulated by signals produced from other molecules. F ...
RNA, PS, mutation unit test
RNA, PS, mutation unit test

... 25. DNA goes through a mutation that changes it from TTT to TTA. Using Figure 13-6 on p. 367, does this change the amino acid? If so, from what to what? ...
Nucleic Acids and DNA
Nucleic Acids and DNA

... – Nontemplate strand or coding strand ...
The importance ofRNA
The importance ofRNA

... position to each of the sugars (riboses) that compose it, while deoxyribonucleic acid (DNA) does not. This seemingly minor difference makes RNA much more flexible than DNA, resulting in a molecule that can adopt many different structures and acquire an array of functions. At the same time, RNA can i ...
Slide ()
Slide ()

... The eukaryotic nuclear genetic code. A, The RNA codons appear in boldface type; the complementary DNA codons are in italics. A = adenine; C = cytosine; G = guanine; T = thymine; U = uridine (replaces thymine in RNA). In RNA, adenine is complementary to thymine of DNA; uridine is complementary to ade ...
Transcription
Transcription

... constitutive, maps between I and Z genes In merozygote F’ Oc Z- / F O+ Z+, β-gal inducible But in Oc Z+ / F O+ Z- constitutive synth of β-gal O Can control Z only when on same chromosome !!! -> cis acting control I is trans acting factor Proteins are synthesized in two stages: 1. DNA is transcribed ...
DNA and Protein Synthesis
DNA and Protein Synthesis

... 1. Topisomerase unwinds DNA and then Helicase breaks H-bonds 2. DNA primase creates RNA primers in spaced intervals 3. DNA polymerase slides along the leading strand in the 3’ to 5’ direction synthesizing the matching Okazaki fragments in the 5’ to 3’ direction 4. The RNA primers are degraded by RNa ...
The Chromosome
The Chromosome

...  There are three types of RNA POL ( I, II, III ).  RNA I transcribes rRNA, it is found in the nucleolus.  RNA POL II is located in the nucleoplasm (the part of the nucleus excluding the nucleolus). Is responsible for synthesizing heterohenous nuclear RNA (hnRNA), the precursor of mRNA.  RNA III ...
Non-coding RNA | Principles of Biology from Nature Education
Non-coding RNA | Principles of Biology from Nature Education

... miRNA binds to transcribed complementary mRNA strands and functions by either blocking translation or targeting the mRNA for degradation. This action of miRNA is similar to another phenomenon uncovered in the 1990s by the American biologists Andrew Fire and Craig Mello. Fire and Mello were using an ...
Slide 1
Slide 1

... that translates to a specific amino acid, or a start or stop message during ...
GBE 335 MOLECULAR GENETICS
GBE 335 MOLECULAR GENETICS

Genomics and Behavior “Central Dogma” Outline
Genomics and Behavior “Central Dogma” Outline

... nucleus to the ribosome • Protein synthesis takes place based on the genetic code • A three base codon codes for an amino acid ...
DNA to Proteins to Natural Selection - Cal State LA
DNA to Proteins to Natural Selection - Cal State LA

... ribosomes) and transfer RNA (tRNA, binds amino acid and inserts into protein at appropriate spot) are used to produce the protein coded by the gene, the process is called translation or protein synthesis ...
DNA - Mrs-Lamberts-Biology
DNA - Mrs-Lamberts-Biology

... DNA prior to cell division so the daughter cells both get a full set. The next two processes occur back to back, and this is how your genes make your body work. Each gene codes for specific protein(s) each individual cell needs to function properly and keep you alive. Many of these proteins are enz ...
Name
Name

... (d) can occur in all organisms. (e) all of the above. 4. Mutations can be: (a) random. (b) beneficial. (c) deadly. (d) inherited from parents. (e) all of the above. 5. A frameshift mutation could result from: (a) a base insertion only. (b) a base deletion only. (c) a base substitution only. (d) dele ...
Chapter 4- Genes and development
Chapter 4- Genes and development

... ______________ organisms- a great way to study gene function • Getting the DNA (a gene) into a cell– ______________ – __________________ (mix DNA with cells) – Retrovirus _____________ (infect a cell) • P element in Drosophila- a transposable element that allows a gene to be inserted into specific ...
Operons: The Basic Concept
Operons: The Basic Concept

... Operons: The Basic Concept • In bacteria, genes are often clustered into operons, composed of – An operator, an “on-off” switch – A promoter – Genes for metabolic enzymes ...
DNA Structure and Function
DNA Structure and Function

... assembly site ...
UNIT 4 PART1 MODERN GENETICS
UNIT 4 PART1 MODERN GENETICS

... between the bases. • Two new molecules are built by attaching new nucleotides to each original strand which acts as a template, or pattern. ...
Overview of the Origin of Life
Overview of the Origin of Life

... as gas circulated electric sparks, (acting as lightening) supplied the energy to drive the chemical reaction • Other experiments branched off from this one including how ATP and DNA were formed.  ...
Exercise 5
Exercise 5

... Reading over this material from nearly three decades ago makes me wish that I had known the material of this course, Chemistry 256, much better before starting the project. The following questions are designed to have you figure out what motivated that part of the research and what we have found out ...
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