Dextromethorphan (DXM)
... or extremely large doses, dextromethorphan may also bind to opiate receptors, inhibit serotonin reuptake, increase dopamine levels and cause adrenergic symptoms, including elevated blood pressure and heart rate. Dextromethorphan is well absorbed orally within 30 minutes. Used as a cough medicine, th ...
... or extremely large doses, dextromethorphan may also bind to opiate receptors, inhibit serotonin reuptake, increase dopamine levels and cause adrenergic symptoms, including elevated blood pressure and heart rate. Dextromethorphan is well absorbed orally within 30 minutes. Used as a cough medicine, th ...
Full text - FNWI (Science) Education Service Centre
... Migraine is a chronic condition of recurrent, throbbing headache generally felt on one side of the head but can also switch from one side to another. Migraines usually begin in early childhood adolescence or young adult life. The headache is characteristically accompanied by nausea, vomiting or loss ...
... Migraine is a chronic condition of recurrent, throbbing headache generally felt on one side of the head but can also switch from one side to another. Migraines usually begin in early childhood adolescence or young adult life. The headache is characteristically accompanied by nausea, vomiting or loss ...
Chronic Fatigue Syndrome
... Chronic Fatigue Syndrome is closely related to another chronic condition, fibromyalgia (FMS). Muscle pain is the prominent symptom of fibromyalgia. However, preliminary studies by the Centers for Disease Control reveal that, for those individuals whose chronic fatigue does not significantly improve ...
... Chronic Fatigue Syndrome is closely related to another chronic condition, fibromyalgia (FMS). Muscle pain is the prominent symptom of fibromyalgia. However, preliminary studies by the Centers for Disease Control reveal that, for those individuals whose chronic fatigue does not significantly improve ...
Zofran
... fentanyl, lithium, tramadol, and intravenous methylene blue). Some of the reported cases were fatal. Serotonin syndrome occurring with overdose of ZOFRAN alone has also been reported. The majority of reports of serotonin syndrome related to 5-HT 3 receptor antagonist use occurred in a post-anesthesi ...
... fentanyl, lithium, tramadol, and intravenous methylene blue). Some of the reported cases were fatal. Serotonin syndrome occurring with overdose of ZOFRAN alone has also been reported. The majority of reports of serotonin syndrome related to 5-HT 3 receptor antagonist use occurred in a post-anesthesi ...
American Society of Clinical Oncology Guideline for Antiemetics in
... dexamethasone, and aprepitant is recommended before chemotherapy. In all patients receiving cisplatin and all other agents of high emetic risk, the two-drug combination of dexamethasone and aprepitant is recommended. The Update Committee no longer recommends the combination of a 5-HT3 serotonin rece ...
... dexamethasone, and aprepitant is recommended before chemotherapy. In all patients receiving cisplatin and all other agents of high emetic risk, the two-drug combination of dexamethasone and aprepitant is recommended. The Update Committee no longer recommends the combination of a 5-HT3 serotonin rece ...
Effects of different doses of venlafaxine on serotonin and
... urine drug screening. Participants met the following inclusion criteria : (1) male, between the ages of 18 and 40 years old ; females were not included to avoid having to control for menstrual cycle or possible metabolic interference with oral contraceptives ; (2) body weight in the normal range as ...
... urine drug screening. Participants met the following inclusion criteria : (1) male, between the ages of 18 and 40 years old ; females were not included to avoid having to control for menstrual cycle or possible metabolic interference with oral contraceptives ; (2) body weight in the normal range as ...
Risk Management Plan Rasagiline tablets
... prescription e.g. St. John's Wort) or pethidine. At least 14 days must elapse between discontinuation of rasagiline and initiation of treatment with MAO inhibitors or pethidine”. Section 4.4: “The concomitant use of rasagiline and dextromethorphan or sympathomimetics such as those present in nasal a ...
... prescription e.g. St. John's Wort) or pethidine. At least 14 days must elapse between discontinuation of rasagiline and initiation of treatment with MAO inhibitors or pethidine”. Section 4.4: “The concomitant use of rasagiline and dextromethorphan or sympathomimetics such as those present in nasal a ...
Relationship between the Serotonergic Activity and Reinforcing
... (Rea et al., 1998), and have low potential for abuse in human subjects (Brauer et al., 1996). Reinforcing efficacy among a series of cocaine analogs was shown to be negatively related to the SERT potency relative to DAT (Roberts et al., 1999). In that study, cocaine analogs with the highest relative ...
... (Rea et al., 1998), and have low potential for abuse in human subjects (Brauer et al., 1996). Reinforcing efficacy among a series of cocaine analogs was shown to be negatively related to the SERT potency relative to DAT (Roberts et al., 1999). In that study, cocaine analogs with the highest relative ...
continuing professional Development PRACTICAL PoINTERS
... minor interactions in green and interactions to be aware of in black. The table quantifies the potential interaction by reporting what are generally the maximum potential increases in serum concentration. Where the percentage increase is given, e.g. 300% increase, then this means that the serum conc ...
... minor interactions in green and interactions to be aware of in black. The table quantifies the potential interaction by reporting what are generally the maximum potential increases in serum concentration. Where the percentage increase is given, e.g. 300% increase, then this means that the serum conc ...
Polycystic ovary syndrome: A review for dermatologists
... PCOS population and are useful first-line agents Lifestyle changes Lifestyle changes are often recommended as firstline treatment for PCOS to benefit overall health. Studies examining dietary interventions show conflicting effects on hirsutism, likely influenced by type of restrictive diet and study ...
... PCOS population and are useful first-line agents Lifestyle changes Lifestyle changes are often recommended as firstline treatment for PCOS to benefit overall health. Studies examining dietary interventions show conflicting effects on hirsutism, likely influenced by type of restrictive diet and study ...
Effects of Pharmaceuticals on Aquatic Invertebrates. Part II: The
... purity >99%, water solubility = 38.4 mg/l at 25C, log KOW = 4.05, and vapor pressure = 8.9E-007 mm Hg (25C). The compound exerts its effects by raising the serotonin level by means of inhibiting neuronal and muscle 5-hydroxytryptamine (5-HT) receptors, thereby increasing the serotonergic synaptic ...
... purity >99%, water solubility = 38.4 mg/l at 25C, log KOW = 4.05, and vapor pressure = 8.9E-007 mm Hg (25C). The compound exerts its effects by raising the serotonin level by means of inhibiting neuronal and muscle 5-hydroxytryptamine (5-HT) receptors, thereby increasing the serotonergic synaptic ...
Prescribing information - Novartis Pharmaceuticals Corporation
... fentanyl, lithium, tramadol, and intravenous methylene blue). Some of the reported cases were fatal. Serotonin syndrome occurring with overdose of ZOFRAN alone has also been reported. The majority of reports of serotonin syndrome related to 5-HT3 receptor antagonist use occurred in a post-anesthesia ...
... fentanyl, lithium, tramadol, and intravenous methylene blue). Some of the reported cases were fatal. Serotonin syndrome occurring with overdose of ZOFRAN alone has also been reported. The majority of reports of serotonin syndrome related to 5-HT3 receptor antagonist use occurred in a post-anesthesia ...
Chapter 16 Cholinesterase Inhibitors
... A, In the absence of MAOIs, much of ingested tyramine is inactivated by MAO in the intestinal wall (not shown in the figure). Any dietary tyramine that is not metabolized in the intestinal wall is transported directly to the liver, where it undergoes immediate inactivation by hepatic MAO. No tyramin ...
... A, In the absence of MAOIs, much of ingested tyramine is inactivated by MAO in the intestinal wall (not shown in the figure). Any dietary tyramine that is not metabolized in the intestinal wall is transported directly to the liver, where it undergoes immediate inactivation by hepatic MAO. No tyramin ...
Risperdal/Risperdal M-Tab/ Risperdal Consta (risperidone)
... At lower dosages, Risperdal is generally well tolerated. Common side effects include sedation, dizziness, headache, nausea, vomiting, constipation, insomnia, and agitation. There is a higher incidence of extrapyramidal symptoms (EPS) when the dosage of Risperdal exceeds 6 mg/day. EPS are neurologica ...
... At lower dosages, Risperdal is generally well tolerated. Common side effects include sedation, dizziness, headache, nausea, vomiting, constipation, insomnia, and agitation. There is a higher incidence of extrapyramidal symptoms (EPS) when the dosage of Risperdal exceeds 6 mg/day. EPS are neurologica ...
Inositol: A Scientific Evaluation Of Its Clinical Ef F E C T
... Levine (1997) completed a meta-analysis of all research studies done using inositol on psychiatric patients. In addition to reviewing the studies on depression, Levine highlighted some interesting findings with obsessive-compulsive (OCD) patients. Serotonin plays a definitive role in obsessive-compu ...
... Levine (1997) completed a meta-analysis of all research studies done using inositol on psychiatric patients. In addition to reviewing the studies on depression, Levine highlighted some interesting findings with obsessive-compulsive (OCD) patients. Serotonin plays a definitive role in obsessive-compu ...
PRODUCT MONOGRAPH PrLUVOX
... On rare occasions development of a serotonin syndrome or neuroleptic malignant syndrome-like events have been reported in association with treatment of LUVOX®, particularly when given in combination with other serotonergic and / or neuroleptic/antipsychotic drugs. As these syndromes may result in po ...
... On rare occasions development of a serotonin syndrome or neuroleptic malignant syndrome-like events have been reported in association with treatment of LUVOX®, particularly when given in combination with other serotonergic and / or neuroleptic/antipsychotic drugs. As these syndromes may result in po ...
Treatment of Tics and Tourette Syndrome | SpringerLink
... Tic Severity Scale (YGTSS) is most widely used in clinical trials. Tics usually present in the first decade of life, with a peak onset at approximately 5–7 years of age. They tend to be most severe between ages 7 and 12, after which there is generally a decline in tic severity. One follow-up study o ...
... Tic Severity Scale (YGTSS) is most widely used in clinical trials. Tics usually present in the first decade of life, with a peak onset at approximately 5–7 years of age. They tend to be most severe between ages 7 and 12, after which there is generally a decline in tic severity. One follow-up study o ...
Case report / Olgu sunumu AN ACUTE DYSTONIA CASE INDUCED
... At thirtieth day of the treatment, she was partially improved but sleeplessness and depressive mood persisted, the doses were justified as fluoxetine (40 mg/day) and trazodone (100 mg/day). During the second month of therapy the patient kept the dose of fluoxetine as ordered, but decreased trazodone ...
... At thirtieth day of the treatment, she was partially improved but sleeplessness and depressive mood persisted, the doses were justified as fluoxetine (40 mg/day) and trazodone (100 mg/day). During the second month of therapy the patient kept the dose of fluoxetine as ordered, but decreased trazodone ...
PLEASE POST THIS SUMMARY IN AREAS WHERE MPTP IS USED
... To date, there has been no report in the literature of the inadvertent exposure of a researcher to MPTP while conducting MPTP experiments. A single report of a research chemist who suffered a fatal exposure to large amounts of MPTP during its synthesis has been documented and represents the only ina ...
... To date, there has been no report in the literature of the inadvertent exposure of a researcher to MPTP while conducting MPTP experiments. A single report of a research chemist who suffered a fatal exposure to large amounts of MPTP during its synthesis has been documented and represents the only ina ...
neuromodulators in invertebrates
... Department of Zoology, University of Otago, Dunedin, New Zealand Institut für Biologische Informationsverarbeitung, Forschungszentrum Jülich, Jülich, Germany In the central nervous system (CNS) of both vertebrates and invertebrates, biogenic amines are important neuroactive molecules. Physiologicall ...
... Department of Zoology, University of Otago, Dunedin, New Zealand Institut für Biologische Informationsverarbeitung, Forschungszentrum Jülich, Jülich, Germany In the central nervous system (CNS) of both vertebrates and invertebrates, biogenic amines are important neuroactive molecules. Physiologicall ...
TRAMADOL – A Drug to be used cautiously
... Tramadol, a centrally acting analgesic structurally related to codeine and morphine, consists of two enantiomers, both of which contribute to analgesic activity via different mechanisms. (+)-Tramadol and the metabolite (+)-O-desmethyltramadol (M1) are agonists of the μ. opioid receptor. (+)-Tramadol ...
... Tramadol, a centrally acting analgesic structurally related to codeine and morphine, consists of two enantiomers, both of which contribute to analgesic activity via different mechanisms. (+)-Tramadol and the metabolite (+)-O-desmethyltramadol (M1) are agonists of the μ. opioid receptor. (+)-Tramadol ...
Body System Adverse Effects
... Delirium, tachycardia, hyperreflexia, shivering, agitation, sweating, muscle spasms, coarse tremors ...
... Delirium, tachycardia, hyperreflexia, shivering, agitation, sweating, muscle spasms, coarse tremors ...
Dextroamphetamine Sulfate Extended
... phenomenon, were observed in post-marketing reports at different times and at therapeutic doses in all age groups throughout the course of treatment. Signs and symptoms generally improve after reduction in dose or discontinuation of drug. Careful observation for digital changes is necessary during t ...
... phenomenon, were observed in post-marketing reports at different times and at therapeutic doses in all age groups throughout the course of treatment. Signs and symptoms generally improve after reduction in dose or discontinuation of drug. Careful observation for digital changes is necessary during t ...
A Review on Benzylpiperazine and Trifluoromethylphenypiperazine
... effects of BZP. Perception of the sensations such as taste, colour or music may also be subjectively enhanced (Nikolova and Danchev 2008). ...
... effects of BZP. Perception of the sensations such as taste, colour or music may also be subjectively enhanced (Nikolova and Danchev 2008). ...
Antihistamine Toxicosis
... loratadine, and terfenadine. Terfenadine is no longer commercially available in the United States because of its cardiotoxic potential 5 but may be available in other countries. 6 Loratadine is available as Claritin and in combination with pseudoephedrine as Claritin-D. These agents are rapidly abso ...
... loratadine, and terfenadine. Terfenadine is no longer commercially available in the United States because of its cardiotoxic potential 5 but may be available in other countries. 6 Loratadine is available as Claritin and in combination with pseudoephedrine as Claritin-D. These agents are rapidly abso ...
Serotonin syndrome
Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.