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Kristen Ray - USD Biology
Kristen Ray - USD Biology

... Prevent reuptake of 5-HT into the pre-synaptic neuron ...
Drugs Used to Treat Autism and their Effectiveness
Drugs Used to Treat Autism and their Effectiveness

... prescribed for anxiety, depression, and/or obsessivecompulsive disorder. Of these only fluoxetine (Prozac) has been approved by the FDA for both OCD and depression in children age 7 and older. • Sertraline (Zoloft) don’t study any names between brackets as above. ...
Alcohol
Alcohol

... – Inhibits ALDH metabolism and causes nausea and hypotension, severe can cause death – Occurs 10-20 minutes after ingestion – Adjunct treatment ...
Typical antipsychotic drugs
Typical antipsychotic drugs

... Loxapine properties are similar to phenothiazines Clozapine has fewer extrapyramidal side effect and greater activity against negative symptoms and its use is with 1.3% first year incidence of potentially fatal agranulocytosis. Other atypical drugs are amisulpride, quetiapine, risperidone and zotepi ...
Antidepressants Sedatives
Antidepressants Sedatives

... – Blocks reuptake of the MAO transmitters NE (norepinephrine) and serotonin. Elevates mood, thereby treating depression. (it doesn’t get dissolved as quickly, keep producing it’s effect.) – Other uses: bipolar disorder, neuropathic pain, insomnia, fibromyalgia, OCD, bladder disorders – Just b/c they ...
Depression and anxiety Lou haiyan(娄海燕)
Depression and anxiety Lou haiyan(娄海燕)

...  Partial agonist at the serotonin 1a receptor.  Relieves anxiety without producing sedation, impairment of motor skills, or memory loss. ...
Historical Perspectives
Historical Perspectives

... Sonata Lunesta Rozerem *contains a two layer coat One layer releases it s immediataely and other layer has a slow release of additional drug ...
Lithium - Wellington ICU
Lithium - Wellington ICU

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Antianxiety, Mood Disorder and Antipsychotic Medications
Antianxiety, Mood Disorder and Antipsychotic Medications

... Consists of a variety of related disorders Does have a genetic predisposition Positive symptoms include CNS stimulation, agitation, behavioral disturbances, delusions, hallucinations, insomnia, and paranoia. Negative symptoms include anhedonia, lack of motivation, blunted affect, poor hygiene, poor ...
Designer and look
Designer and look

... hyperthermia, which becomes particularly hazardous in the typically hot, crowded rave settings where ecstasy use is most common. Most deaths associated with ecstasy are complications of hyperthermia. One such complication commonly occurs when overheated users drink too much water, causing a fluid im ...
Depression
Depression

... Make time for pleasurable activities – Even though you may not feel as motivated, or get the same amount of pleasure as you used to, commit to scheduling some fun activity each day – for example, doing a hobby, listening to music or watching a video. Spend time with people who can support you – It’s ...
Acute poisonings with substance of abuse
Acute poisonings with substance of abuse

... Blood sample – no answer, urine analysis – “possibility of cocaine metabolites” ...
The Psychology and Physiology of Street Drugs Amie J. Hatch
The Psychology and Physiology of Street Drugs Amie J. Hatch

... NMDA receptor blocker and dopamine agonist Reports of euphoria and enlightenment ...
Psychopharmacology and Other Biologic Treatments
Psychopharmacology and Other Biologic Treatments

... and broken down into smaller substances (metabolites) that are usually inactive • Lipid-soluble drugs become more water soluble, so they may be more readily excreted. • Most metablism is carried out in the liver. ...
NEUROTRANSMITTERS IN HEALTH AND DISEASE
NEUROTRANSMITTERS IN HEALTH AND DISEASE

... Serotonin 5-HT3 receptors and N & V • 5-HT3 in the CTZ (chemoreceptor trigger zone of the brain stem) is responsible for vomiting from chemo and post-anesthesia • 5-HT3 in the duodenum is responsible for nausea– “the organ of nausea” • Anticipatory nausea and vomiting ...
SSRI`s - Seroxat User Group
SSRI`s - Seroxat User Group

... The information presented in Interactions™ is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, case reports, and/or traditional usage with sources as cited in each topic. The results reported may not necessarily oc ...
Developmental Neurotoxicity from Environmental Chemical Exposures
Developmental Neurotoxicity from Environmental Chemical Exposures

... • Developmental neurotoxicants likely to play an important role in the increased incidence of childhood behavioral disorders including ASD • Disparate mechanisms and effects converge on common final pathways — different agents may produce similar outcomes — different agents may produce additive/syne ...
Patient Information Sheet
Patient Information Sheet

... ● babies born to mothers who took selective serotonin reuptake inhibitors (SSRIs), one of the medicines in Symbyax, ● 20 weeks or later in their pregnancies, ● had a higher chance (were 6 times as likely) to have persistent pulmonary hypertension (PPHN), ● than babies born to mothers who did not tak ...
Psychopharmacology
Psychopharmacology

... Agomelatine is a novel antidepressant that is both a melatonergic agonist and a 5-HT 2C antagonist. Agomelatine also enhances dopaminergic and adrenergic input to the frontal cortex. Dose 25 – 50 mg at bedtime. Not avaialble in US. ...
Update on Antidepressants
Update on Antidepressants

...  Fetzima (levomilnazopram) ...
CNS Stimulants
CNS Stimulants

...  Serotonin ...
Antidepressant agents - به سامانه مديريت
Antidepressant agents - به سامانه مديريت

...  At high doses or combined with other drugs an exaggerated response can occur  This is due to increased amounts of serotonin  Alters cognitive function, autonomic function and neuromuscular function  Potentially fatal ...
Antidepressants and neuroleptic
Antidepressants and neuroleptic

... increased blood pressure ➔ stroke ➔ death increased heart rate ➔ heart attack ➔ death ...
Psychopharmacology and Other Biologic Treatments
Psychopharmacology and Other Biologic Treatments

... plasma from which a drug is completely removed per unit time. • Half-life: Time required for plasma concentrations of the drug to be reduced by 50%. • Only a few drugs eliminated by kidneys (lithium) • Most excreted in the liver – excreted in the bile and delivered to the intestine – may be reabsorb ...
PARoxetine hydrochloride (par-ox-e
PARoxetine hydrochloride (par-ox-e

... health care professional if patient demonstrates significant increase in anxiety, nervousness, or insomnia. Assess for suicidal tendencies, especially during early therapy. Restrict amount of drug available to patient. Risk may be increased in children, adolescents, and adults ⱕ24 yr. Assess for ser ...
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Serotonin syndrome



Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.
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