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Chapter 5: Structure and function of macromolecules
Chapter 5: Structure and function of macromolecules

... Nucleic acid polymers (DNA and RNA) consist of joining together of monomers called nucleotides. The order of nitrogenous bases extending from phosphate-sugar backbone determines amino acid sequence in proteins. DNA consists of 2 chains of nucleotides that spiral an imaginary axis to form a double he ...
Sophomore Dental and Optometry Microbiology
Sophomore Dental and Optometry Microbiology

... (DNA ------------> mRNA -------------> protein) • binds initiation site (Ribosome binding site, ShineDelgarno sequence) in mRNA • must have 2o structure (base pairs with self) • Changes in critical areas likely detrimental • DNA that encodes rRNA is highly conserved among bacteria of common ancestry ...
Superhero Worksheet 2 - Highline Public Schools
Superhero Worksheet 2 - Highline Public Schools

... Learning Target: I will be able to illustrate how genes make proteins Background: Part 1: You were just an ordinary student until today. Your DNA is getting changed, and you will select the 2 powers that your DNA will now be able to create. Unfortunately, the powers are only given in the form of ami ...
antisense orfs, codon bias and the evo lu tion of the ge netic code
antisense orfs, codon bias and the evo lu tion of the ge netic code

... Hauptman-Woodward Institute, Buffalo, NY 14203 ...
animations of selected figures
animations of selected figures

... CTTAA small fragment G G CTTAA ACGTC ...
CSCE590/822 Data Mining Principles and Applications
CSCE590/822 Data Mining Principles and Applications

... Back-propagation algorithm For Mult-layer NN, the errors of hidden layers are not known  Searches for weight values that minimize the total error of the network over the set of ...
Biochemisty
Biochemisty

... repeating unit of the cellulose molecule. Groups of 30 to 40 of these chains laterally hydrogen-bond to form crystalline or para-crystalline microfibrils. ...
The Chemistry of the cell
The Chemistry of the cell

... Protein Synthesis Intracellular • In cells, this reaction does not occur directly; instead the amino acid is first activated by attachment to a transfer RNA molecule through an ester bond. • This aminoacyl-tRNA is then a substrate for the ribosome which catalyzes the attack of the amino group of th ...
High-Salt Precipitation Solution Manual ver.1
High-Salt Precipitation Solution Manual ver.1

... (4) Add 0.25 ml of the High-Salt Precipitation Solution and mix by inverting.* (5) Leave standing at room temperature for 5-15 min. (6) Centrifuge (10 K × g, 4–20°C, 15 min). (7) Add 70% ethanol (1-1.5 ml) to the precipitates and lightly vortex. (8) Lightly air dry the precipitates, and then dissolv ...
Biology - Raleigh Charter High School
Biology - Raleigh Charter High School

... long and not visible with a light microscope. The chromatin fibers coil up to form chromosomes  Also known as 30-nm chromatin fiber or 30-nm fiber ...
10C Cellular respiration worksheet
10C Cellular respiration worksheet

... 5. The two strands of a DNA double helix are antiparallel. This means that _____. A) the two strands are mirror images B) only one of the two strands can be used as a template for replication, since DNA polymerase only works in one direction C) one strand is actually composed of RNA D) one strand ru ...
Glucose/Galactose Binding Protein (GGBP)
Glucose/Galactose Binding Protein (GGBP)

... differentiation, chromosomal segregation, and circadian rhythm. In humans, CK1s have been linked to neurodegenerative diseases and cancer. We are investigating regulation of CK1 activity by phosphorylation, using yeast CK1 protein kinases as models. We have previously identified phosphorylation site ...
X-ray Crystallography
X-ray Crystallography

... wavelength used for the diffraction experiment. Atoms in proteins which are suitable for this purpose are sulfur or heavier atoms, for example metal ions in metalloproteins. The most commonly used atom for phase determination via MAD, however, is selenium, since it is usually possible to replace the ...
Section L Regulation of Transcription in Prokaryotes
Section L Regulation of Transcription in Prokaryotes

... Transcription regulation patterns: • By transcriptional repressors: such as the lac repressor; • By transcriptional activators: such as the CRP; • By different s to direct RNApol binding different promoter: Functions of s factors :  The abb’w core enzyme of RNA polymerase is unable to start transcr ...
DNA - benanbiology
DNA - benanbiology

... • DNA carries the genetic code of the organism. Genetic code of each organism is different from each other(except identical twins). Genetic code differs in the base sequences. ...
On the Importance of Amino Acid Sequence and Spatial Proximity of
On the Importance of Amino Acid Sequence and Spatial Proximity of

... number of Cα-Cα interactions over the range 0–60 Å for specific residue types and fit this to simple sigmoids. The fits show no clear residue dependence at the range of interaction distances typically known to be relevant to protein structure and folding (0–10 Å). This is not surprising since the fi ...
The dark side of ribosome biogenesis
The dark side of ribosome biogenesis

... course of this project, several other genetic diseases have been associated with such defects, leading to the definition of a new class of diseases (ribosomopathies) for which DBA is a central model. We are currently trying to define simple protocols to detect anomalies in ribosome production and to ...
PowerPoint Presentation - AGRI-MIS
PowerPoint Presentation - AGRI-MIS

... Arabidopsis gai mutant intragenic suppressor of gai loss of function allele ...
PowerPoint 簡報 - Academia Sinica
PowerPoint 簡報 - Academia Sinica

... for side reactions, and they are likely to contain deletion sequences. On the other hand, short peptides (<10 amino acids) may generate antibodies that are so specific in their recognition that they cannot recognize the native protein or do so with low affinity. The typical length for generating ant ...
lec-02-handout
lec-02-handout

... Primase: catalyzes synthesis of small pieces of RNA complementary to single stranded DNA that provides the free 3’ OH end needed for DNA replication to begin. DNA polymerase: synthesizes DNA by linking together deoxyribonucleoside monophosphates in an order directed by the complementary sequences of ...
- DigitalCommons@Linfield
- DigitalCommons@Linfield

... Introduc9on       The   central   dogma   theory   relates   how   DNA   is   transcribed   into   messenger   RNA   (mRNAs)   and   then   translated   into   proteins.   Since   the   nucleus   contains   the   majority   of   the   DNA ...
PCR applications in diagnosis of parasitic diseases
PCR applications in diagnosis of parasitic diseases

... florescence” in each cycle. It is used in diagnosis of many conditions other than parasitological infections. ...
Heat Shock Protein 70
Heat Shock Protein 70

... tissues. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist. Summary and Explanation: Heat ...
slides
slides

... 1. For homologous proteins (similar ancestry), this provides the “gold standard” for sequence alignment--elucidates the common ancestry of the proteins. 2. For nonhomologous proteins, allows us to identify common substructures of interest. 3. Allows us to classify proteins into clusters, ...
Function
Function

... functions associated with ribosome Have pulled out sets of ribosomal proteins on basis of phylogenetic profile Linked proteins need not be homologues nor be localized in genome ...
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Gene expression



Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.
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