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purine
purine

... • Hydrolyzing a phosphate from ATP is relatively easy G°’= -30.5 kJ/mol – If exergonic reaction released energy into cell as heat energy, wouldn’t be useful – Must be coupled to an endergonic reaction ...
acids and bases
acids and bases

... and is important in maintaining tertiary structure of proteins and enzymes upon which life depends. Ingested heavy metal ion seeks out and coordinates with amino acid sulfur, disrupting protein structure and deactivating the protein. Eventual death is the usual result of prolonged exposure to heavy ...
Ch18.doc
Ch18.doc

... because alanine-transaminase will produce pyruvate which as soon as it is produced will be reduced to lactic acid using NADH. NADH has a strong absorbance at 340 nm, so the rate of decrease in 340 nm absorbency is due to the rate of the transaminase present in a sample. ...
Chem*3560 Lecture 23: Phospholipid Biosynthesis
Chem*3560 Lecture 23: Phospholipid Biosynthesis

... disrupt bilayer structure, and must be modified by adding a polar headgroup. The head group is a hydroxyl or alcohol compound that forms an ester bond with the phosphate of phospahtidic acid. The makes the product a phosphodiester, phosphate with two ester groups. ...
P site - Industrial ISD
P site - Industrial ISD

... pair of complimentary nucleotides with another nucleotide pair is called a base-pair substitution. • Some base-pair substitutions have little or no impact on protein function. • In silent mutations, alterations of nucleotides still indicate the same amino acids because of redundancy in the genetic c ...
UNIT I Biomolecules - McGraw
UNIT I Biomolecules - McGraw

... Finally, two or more separately folded protein strands may associate with each other to form the active form of a protein, which falls under the category of quaternary structure. The conventions and depictional devices for tertiary and quaternary structures are identical—the only difference is that ...
as a PDF
as a PDF

... acid, mineral and fatty acid compositions and profiles of such fresh vegetables can have deleterious effects on their acceptability as a food source. To our knowledge, no information is available on the levels of sugars, fatty acids, proteins (free amino acids) and minerals in kale leaf. For leaf nutr ...
Basic Cell Chemistry :
Basic Cell Chemistry :

Catalytic, Enantioselective Alkylation of r
Catalytic, Enantioselective Alkylation of r

... are almost unstudied in Lewis acid-catalyzed reactions,3 but are especially attractive imine substrates for the efficient syntheses of natural product precursors,4 pharmaceutically active compounds,5 and nonnatural amino acids;6 the last category has recently received much attention as peptidomimeti ...
Characterization of the novel antibacterial peptide Leucrocin from
Characterization of the novel antibacterial peptide Leucrocin from

... can influence activity. A systematic understanding of the relationship between peptide structure and activity is an important area ...
Changes in chemical composition in male turkeys
Changes in chemical composition in male turkeys

... In general, the protein and ash contents in FFB declined with increasing age, whereas the lipid content, and consequently the gross energy content, increased substantially from 3 wk of age onward (Table 1). The composition of FFB at 1 wk of age appeared to be different from the general tendency obse ...
slides - NMRbox
slides - NMRbox

... reorientation. NMR assignment is complicated, and generally requires 13C / 15N labeled protein. Y Aubin, DJ Hodgson, WB Thach, G Gingras, and S Sauvé: Monitoring Effects of Excipients, Formulation Parameters and Mutations on the High Order Structure of Filgrastim by NMR. Pharm Res., 32, 3365-3375 (2 ...
role of aldehyde oxidase and keto
role of aldehyde oxidase and keto

AP Biology
AP Biology

AQA A-level Biology
AQA A-level Biology

... Monosaccharides such as α-glucose are the monomers that join together to make many other carbohydrates. Two α-glucose molecules join by condensation to form a molecule of the disaccharide maltose. The bond forms between carbon 1 of one α-glucose molecule and carbon 4 of the other, and is called a gl ...
lecture04_05
lecture04_05

... • For aligning amino acids, we need a scoring matrix of 20 rows  20 columns • Matrices represent biological processes – Mutation causes changes in sequence – Evolution tends to conserve protein function – Similar function requires similar amino acids ...
1 - AQA
1 - AQA

... Monosaccharides such as α-glucose are the monomers that join together to make many other carbohydrates. Two α-glucose molecules join by condensation to form a molecule of the disaccharide maltose. The bond forms between carbon 1 of one α-glucose molecule and carbon 4 of the other, and is called a gl ...
Multiple Choice Questions- Chemistry and Metabolism of nucleotides
Multiple Choice Questions- Chemistry and Metabolism of nucleotides

... 17- A physician evaluates a 32-year-old patient for fatigue. The patient is found to have an elevated white blood cell count and an enlarged spleen. A referral to an oncologist results in a diagnosis of chronic myelogenous leukemia. Treatment with hydroxyurea, a ribonucleotide reductase inhibitor is ...
Partial purification of fatty acid synthetase from Streptomyces
Partial purification of fatty acid synthetase from Streptomyces

... mol.wt. 180000. A similar purification was obtained after sucrose-gradient centrifugation to give material with s20,w 8 S. Thus the synthetase migrated as a single species during these Filamentous bacteria of the genus Streptomyces are extremely procedures (with a consistent recovery of over 80%), a ...
Request reprint ©
Request reprint ©

PDF
PDF

... demonstrated that Ae2-L-Lys-o-Ala-D-iactate and other esters and thioesters can interact with o,opeptidases and transpeptidases [12,14], which suggests that the modified precursor, once incorporated into linear peptidoglycan, could take part in the final stage of peptidoglycan synthesis. As this rea ...
Lipid Metabolism Catabolism Overview
Lipid Metabolism Catabolism Overview

... chain, saturated fatty acids • Differs from Fatty acid degradation – In cytoplasm, not matrix – Acyl carrier protein rather than CoA – Enzymes linked in a complex ...
Ion specific effects of sodium and potassium on the catalytic activity
Ion specific effects of sodium and potassium on the catalytic activity

... Since peptide substrate 1 contains a Glu residue which might itself be responsible for the differences in the affinity of positively charged ions, we measured the kinetics with a second peptide substrate. Peptide 2, 2-aminobenzoyl-TINleNphQR-NH2, is based on the p2-NC cleavage site of the HIV Gag p ...
handout
handout

...  From the 5’ cap to the AUG start codon is called the untranslated region UTR.  Translation initiation factors are needed for the small sub-unit to find the 5’ cap  Eukaryotic initiation uses a Met amino acids not f-Met. ...
Chemical-Scale Studies of the Phe-Pro Conserved Motif in the Cys
Chemical-Scale Studies of the Phe-Pro Conserved Motif in the Cys

... There is considerable evidence supporting a specific interaction in a PhePro sequence that stabilizes the cis form of the Pro. This could possibly involve a polar–π interaction in which polarized C–H bonds (Cδ−–Hδ+) on the proline interact favorably with the negative electrostatic potential on the f ...
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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, which are organic compounds in which multiple amino acids are linked via amide bonds, also known as peptide bonds. The biological process of producing long peptides (proteins) is known as protein biosynthesis.
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