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Amino Acid Structure
Amino Acid Structure

...  Myoglobin is a globular protein displaying the tertiary level of structure  Myoglobin is a protein found in muscle cells  Proteins consisting of more than one polypeptide chain display quaternary structure  Haemoglobin is a protein consisting of more than one polypeptide chain  Haemoglobin co ...
Proteins
Proteins

... complex association of several polypeptide chains. Each of these polypeptide chains have a primary, secondary and tertiary structure. Collagen (gives your skin its strength) is formed by several chain making like a rope. ...
No Slide Title
No Slide Title

... • To do this we rely on the 1D (if the molecule is small enough), COSY and TOCSY spectra. Last time we saw how a whole spin system is easily identified in a TOCSY. • In peptides, there will be an isolated line for each amino acid starting from the NH that will go all the way down to the side chain p ...
List of protein families currently covered by SVMProt
List of protein families currently covered by SVMProt

... It has 16 alanines (n1=16) and 14 glutamic acids (n2=14). The composition for these two amino acids are n1×100.00/(n1+n2)=53.33 and n2×100.00/(n1+n2)=46.67 respectively. There are 15 transitions from A to E or from E to A in this sequence and the percent frequency of these transitions is (15/29)×100 ...
Biochemistry Review Reteach
Biochemistry Review Reteach

... Base your answers to questions 5 and 6 below on the reading passage that follows and your knowledge or biology. A student ground 1 gram of fresh liver in a mortar, placed the ground liver in a test tube, and added 1 ml of peroxide. The gas that was generated was collected. A glowing splint burst in ...
Biology I SB1bc Enzymes and Macromolecules Test Study Guide
Biology I SB1bc Enzymes and Macromolecules Test Study Guide

... “Reusable” proteins that put together or break down substrates to form products 2. Since enzymes are proteins they are made of ……what? Amino acids joined by peptide bonds 3. The energy needed to start a chemical reaction is called? Activation Energy (EA) 4. How do enzymes increase the rate or speed ...
Biology I SB1bc Enzymes and Macromolecules Test Study Guide
Biology I SB1bc Enzymes and Macromolecules Test Study Guide

... “Reusable” proteins that put together or break down substrates to form products 2. Since enzymes are proteins they are made of ……what? Amino acids joined by peptide bonds 3. The energy needed to start a chemical reaction is called? Activation Energy (EA) 4. How do enzymes increase the rate or speed ...
Document
Document

... Macromolecules are often polymers. – long molecule built by linking together small, similar subunits  Dehydration synthesis removes OH and H during synthesis of a new molecule.  Hydrolysis breaks a covalent bond by adding OH and H. ...
Levels of protein structure:
Levels of protein structure:

... (one to the next) via dehydration synthesis, involving the carboxyl group of one a.a and the amino group of the next a.a. This covalent bond is often called a peptide bond, but it's still a covalent bond. Small proteins might contain 30 - 50 a.a.; large ones can have some hundreds of a.a. Note that ...
Molekul - Universiti Kebangsaan Malaysia
Molekul - Universiti Kebangsaan Malaysia

... and macromolecule that are formed from 4 fundamental elements: C (carbon) H (hydrogen) O (oxygen) N (nitrogen) P (phosphorus) and others ...
Fatty oxidation, Amino acid degradation and energy metabolism
Fatty oxidation, Amino acid degradation and energy metabolism

... 12. Which metabolic pathway is defective in Maple syrup urine disease? Name the enzyme and the amino acids involved. 13. Which cofactor or coenzyme acts as a one-carbon group carrier (e.g. methyl group) and which one as amino gp carrier? ...
Acid - Perkins Science
Acid - Perkins Science

Macromolecules
Macromolecules

... carbohydrates, proteins, lipids and nucleic acids and together they make up the four major macromolecules. Slide 3 The monomers for each of the macromolecules are synthesized by the cell during regular metabolic functions. Some of the twelve key intermediates that you learned about earlier provide t ...
DCC-promoted peptide coupling
DCC-promoted peptide coupling

... A range of alcohols, including even some tertiary alcohols, can be esterified using a carboxylic acid in the presence of DCC and a catalytic amount of DMAP. DCC-promoted peptide coupling During protein synthesis (such as Fmoc solid-state synthesizers), the N-terminus is often used as the attachment ...
Synthesis and Characterization of Peptide Nucleic Acid for
Synthesis and Characterization of Peptide Nucleic Acid for

... small molecules. Even more, small molecules such as these may even be effective anti-viral therapeutics by neutralizing the RNA genome of devastating retro viruses (2). One class of such small molecules is PNAs. These differ from traditional nucleic acids’ structure by having a backbone consisting o ...
of proteins
of proteins

DNA, RNA, Protein Synthesis
DNA, RNA, Protein Synthesis

... • This process takes place in the cytoplasm on ribosomes • Both mRNA and tRNA are necessary for this process ...
Chapter 2 – Chemical Composition of the Body
Chapter 2 – Chemical Composition of the Body

... – 20 different amino acids can be used in constructing a given protein. – Each amino acid contains an amino group (NH2) at one end and carboxyl group (COOH) at the other end. ...
Chapter 3- DNA, Proteins and Proteomes
Chapter 3- DNA, Proteins and Proteomes

... We’ve all heard that DNA is important because it holds the ...
AMINO ACIDS I. Function of amino acids A. Building blocks of
AMINO ACIDS I. Function of amino acids A. Building blocks of

... 2. Composition of a protein can be used to identify a protein B. Determination of primary sequence of a polypeptide 1. Preparation of peptides for sequencing a. Removal of disulfide bridges i. reducing agent ( -mercaptoethanol or dithiothreitol) ii. derivatize sulfhydryls to block disulfides from re ...
Chapter5 The Structure and Functionof Macromolecules Discussion
Chapter5 The Structure and Functionof Macromolecules Discussion

... 12. Distinguish between a protein and a polypeptide. 13. Explain how a peptide bond forms between two amino acids. 14. List and describe the four major components of an amino acid. Explain how amino acids may be grouped according to the physical and chemical properties of the R group. 15. Explain wh ...
Sample Preparation Methods for MS Based Proteomics
Sample Preparation Methods for MS Based Proteomics

... 1. Enzymes isolated from different sources may display very different activity(Roche vs WAKO Lys-C) and have different contaminants 2. Asp-N: •has not been sequenced, so you will not identify Asp-N peptides in database searching. •is ametallo-protease, thus chelating agents will inactivate it. 3. Co ...
structural organization
structural organization

... themselves. Held together by H bonds. Each amino acid is spatially related to its neighbour in the same way, is the Secondary Structure of Protein. It may take any form either α-Helix or β pleated sheet ...
Lecture 3
Lecture 3

... themselves. Held together by H bonds. Each amino acid is spatially related to its neighbour in the same way, is the Secondary Structure of Protein. It may take any form either α-Helix or β pleated sheet ...
a. carbohydrates - Valhalla High School
a. carbohydrates - Valhalla High School

... atoms present in a molecule: • Empirical formula – formula showing SIMPLEST proportions of atoms in a compound – Ex.: CH • Molecular formula – formula showing the EXACT COMPOSITION of a compound Ex.: C2H2 • Structural formula – Shows number and kind of atoms AND how they are BONDED TO EACH OTHER – E ...
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Peptide synthesis

In organic chemistry, peptide synthesis is the production of peptides, which are organic compounds in which multiple amino acids are linked via amide bonds, also known as peptide bonds. The biological process of producing long peptides (proteins) is known as protein biosynthesis.
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