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Cocaine - Computer Science
Cocaine - Computer Science

... sessions. This model, however, cannot be readily used to detect drug use in the field as it does not distinguish from similar effects that are observed during other confounding events in daily life (e.g., physical activity). In [12], [13], the authors describe preliminary investigation of a proposed ...
Review: Colchicine, current advances and future prospects
Review: Colchicine, current advances and future prospects

... a toxic natural compound and secondary metabolite commonly produced by plants like Colchicum autumnale and Gloriosa superba. It is originally used to treat rheumatic complaints, especially gout, and still finds its uses for these purposes today despite dosing issues concerning its toxicity. It is al ...
What is an optimal dosage regimen - Physiologie et Thérapeutique
What is an optimal dosage regimen - Physiologie et Thérapeutique

... – less frequent selection of resistant bacteria than late treatments (32 hours after the infection) ...
course course
course course

... observations criminal justice and counseling personnel see on a daily basis. Topics include metabolism, excretion and evaporation of ethanol from the human body and how these processes affect chemical tests of breath, blood, and urine. One section will discuss the difference between "intoxication" a ...
Evaluating Statin Drugs to Treat High Cholesterol and
Evaluating Statin Drugs to Treat High Cholesterol and

... than 190 mg/dL, those who have heart disease or have previously suffered a heart attack or stroke, and those with diabetes who have a high risk of heart attack or stroke—should start taking a statin as initial therapy. But for people who don’t fall into those categories and have a 10-year risk of he ...
prevalence, risk and characteristics of impaired drivers
prevalence, risk and characteristics of impaired drivers

... the national setups of the studies, implying that a blood and/or saliva sample was collected from each driver in the study and confirmation analysed for the same number of substances in all countries. The guidelines also gave advice on how to collect information on a random sample of drivers at all ...
Ensuring balance in national policies on controlled substances
Ensuring balance in national policies on controlled substances

... society from the consequences of dependence. However, equal emphasis has not been placed on the other fundamental objective of the treaties of ensuring that controlled substances are available for medical and scientific purposes. As a result, the health benefits that can be derived from medicines co ...
pharmacology_2
pharmacology_2

... 28.Propranolol produces most of its important effects by antagonizing the beta adrenergic effects of catecholamines released by sympathetic nerve stimulation or from the adrenal medulla. It therefore results in all of the following EXCEPT: A. negative inotropic effect on the heart B. bronchoconstric ...
organic volatile impurities and their regulatory limits
organic volatile impurities and their regulatory limits

... production processes. The organic solvents are widely used in pharmaceutical industry[1]. Residual solvents in pharmaceuticals, commonly known as organic volatile impurities (OVIs), are chemicals that are either used or produced during the manufacture of active pharmaceutical ingredients (APIs), exc ...
ACCELERATED INDUCTION OF ETORPHINE IMMOBILIZATION IN BLUE WILDEBEEST BY THE ADDITION OF HYALURONIDASE
ACCELERATED INDUCTION OF ETORPHINE IMMOBILIZATION IN BLUE WILDEBEEST BY THE ADDITION OF HYALURONIDASE

... by baiting a mixture of horse and mule pellets with diazepam. The experimental animals had their food cut by half two days before dosing and all food was withheld the day prior to dosing. In total 105 deer from six different species were caught in large pens using this method. The most effective and ...
Natural Treatment Alternative for Psoriasis
Natural Treatment Alternative for Psoriasis

... leucocyte infiltration and stimulate keratinocyte cell growth (Ben-Arye et al., 2003, Leung et al., 1993, Naukkarinen et al., 1989). The relationship between human, plant and plant derived products is very old. Plants have been therapeutically used by human in diverse physiological disorders startin ...
What are psychedelics?
What are psychedelics?

... The seeds of several types of tropical lianas have been used by the Indians in Mexico in their rituals for a long time. One of the first Spaniards who observed those rituals wrote in his book: “…and when the priests want to communicate with their gods and to receive their message they eat from this ...
Talwin Nx (pentazocine and naloxone hydrochlorides)
Talwin Nx (pentazocine and naloxone hydrochlorides)

... CNS Effect. Caution should be used when pentazocine is administered to patients prone to seizures; seizures have occurred in a few such patients in association with the use of pentazocine though no cause and effect relationship has been established. Porphyria. Particular caution should be exercised ...
SIMPLE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR DETERMINATION  OF NORFLOXACIN IN PLASMA AND APPLICATION IN BIOEQUIVALENCE STUDY 
SIMPLE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR DETERMINATION  OF NORFLOXACIN IN PLASMA AND APPLICATION IN BIOEQUIVALENCE STUDY 

... Standard  plasma  samples  with  concentration  range  of  30‐2500  ng/mL  were  prepared  by  spiking  different  concentration  of  norfloxacin  working  standard  solutions  into  blank  human  plasma.  Standard  calibration  curve  was  constructed  by  plotting  the  peak  height  of  norfloxac ...
Hypoglossal Nerve Response to 5-HT3 Drugs Injected into the XII
Hypoglossal Nerve Response to 5-HT3 Drugs Injected into the XII

... Adult male Sprague-Dawley rats (Charles River) weighing 320-390g were used. All procedures were approved by the Institutional Animal Care and Use Committee of the University of Pennsylvania. ...
[Salvia divinorum - a potential drug for abuse]
[Salvia divinorum - a potential drug for abuse]

... Selective kappa receptoragonists have been shown to produce analgesic effects with potential for reduced tolerance and dependence. However, psychotomimesis (hallucinogenic and/or psychotic effects), dysphoria and diuresis have been observed with their therapeutic use (Tidgewell et aI., 2004). In add ...
of poor ORIGINAL ARTICLES
of poor ORIGINAL ARTICLES

... somal monooxygenase reaction that catalyzes the 4hydroxylation of S-mephenytoin. In monooxygenase reactions, cytochrome P-450 isozymes are responsible for substrate binding and the stereo- and regioselectivity of the oxidation reactions. Our present findings are therefore consistent with the hypothe ...
Evaluation of Dependence and Withdrawal in Clinical Trials
Evaluation of Dependence and Withdrawal in Clinical Trials

... amount of it to achieve a certain effect (tolerance) and eliciting drugspecific physical or mental symptoms if drug use is abruptly ceased (withdrawal). - It is associated with the repeated use of both known drugs of abuse and drugs with no abuse potential. (For example, the “propranolol withdrawal ...
Osmotic-Controlled Release Oral Delivery System
Osmotic-Controlled Release Oral Delivery System

... depends on the osmotic pressure generated by the core components and the permeability of the membrane coating. As the core absorbs water, it expands in volume, which pushes the drug solution or suspension out of the tablet through one or more delivery ports. The key distinguishing feature of osmotic ...
Republic of Palau - World Health Organization
Republic of Palau - World Health Organization

... To convert from teaspoonful to ml: Household measures such as teaspoons vary in size greatly. However, one teaspoonful may be taken approximately equivalent to 5 ml ...
Drug Policy in Context - DigitalCommons@UM Carey Law
Drug Policy in Context - DigitalCommons@UM Carey Law

... Throughout the twentieth century, however, the reality likely was somewhat more complex and the similarities between the two more pronounced than might have seemed the case.17 More recently, there has been something of a convergence of the two systems. Perhaps out of moral, political, and fiscal fat ...
In Vitro Cytotoxicity, Protein Binding, Red Blood Cell Partitioning
In Vitro Cytotoxicity, Protein Binding, Red Blood Cell Partitioning

... cological information on the drug is limited (2). Oxaliplatin exhib ited no cross-resistance with cisplatin when tested in cisplatinresistant L1210 tumors both in vivo and in vitro (6). In order to gain more information about the differences between oxaliplatin and other platinum complexes and to pr ...
Postoperative nausea and vomiting
Postoperative nausea and vomiting

... combination without side effects is a combination of dexamethasone and 5-HT3 receptor antagonist. In particular, dexamethasone is more effective when administered at the beginning of surgery, due to its relatively slow onset. Despite its well-established efficacy, little is known regarding the mecha ...
Validation of a Bile Duct Cannulation Rat Model | Charles River
Validation of a Bile Duct Cannulation Rat Model | Charles River

... and TPR, is important. Bilirubin is useful for measuring liver dysfunction because it is metabolized and eliminated by the liver. As a liver-specific enzyme, ALT is a generally considered a good indicator of liver health since it is released from hepatocytes into the systemic circulation upon cellul ...
Medicinal uses of licorice through the millennia
Medicinal uses of licorice through the millennia

... by-products have also been used as an excellent compost medium for mushrooms, the reasons for which still remain unknown [4,5]. Beginning in the late 1940s and extending well into the 1950s. there was a growing interest in the metabolic activity of glycyrrhetinic acid. Investigations into various si ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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