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PHT Medicines Management Policy - Portsmouth Hospitals NHS Trust
PHT Medicines Management Policy - Portsmouth Hospitals NHS Trust

... Health Authority which has since changed its name to NHS England. Patient Group Directions (PGD) A specific written instruction for the supply or administration of medicines to clinical groups of patient who may not be individually identified before presentation for treatment. ...
Drug List - The North Carolina Office of EMS
Drug List - The North Carolina Office of EMS

...  26-Overdose/Toxic Ingestion Indications/Contraindications:  Binds, or absorbs, various chemical agents and drugs from the GI tract  Combined with Sorbitol to promote GI motility ...
“Take Your Pill”: The Role and Fantasy of Pills in Modern Medicine
“Take Your Pill”: The Role and Fantasy of Pills in Modern Medicine

... one tries to monitor and ‘‘subtract’’ the placebo effect that helps a substantial proportion of patients to get better even when taking an inert compound. But in actual clinical practice this is not a ‘‘subtractive’’ but an ‘‘additive’’ element, one that is ultimately contributed by the patient’s bo ...
AusPAR: Perampanel (as hemisesquihydrate)
AusPAR: Perampanel (as hemisesquihydrate)

... This is an application for a new chemical entity for Australian regulatory purposes. Perampanel was approved for the indication proposed by the sponsor in the USA in 2012 (see Table 1). It was determined to be a Class III controlled substance in the USA. Perampanel is also approved for the proposed ...
Biodegradable Janus Nanoparticles for Local Pulmonary Delivery of
Biodegradable Janus Nanoparticles for Local Pulmonary Delivery of

... treatment by inhalation. The particles were synthesized using binary mixtures of biodegradable and biocompatible materials. The particles did not demonstrate cyto- and genotoxic effects. Janus particles were internalized by cancer cells and accumulated both in the cytoplasm and nuclei. After inhalati ...
The use of cannabinoids in animals and therapeutic implications for
The use of cannabinoids in animals and therapeutic implications for

... Although cannabinoids have been attracting attention for many years, the last four decades have brought completely new and scientifically wellfounded insights into their therapeutic potential. Since 1975 more than 100 controlled clinical trials with cannabinoids (or whole-plant preparations) for sev ...
Organised Crime and Drugs in Sport
Organised Crime and Drugs in Sport

... anti-doping rule violations. While intelligence confirms the use of peptides in major sporting codes, it further suggests that individuals in a range of other codes may also be using peptides. Multiple players across some sporting codes and specific clubs within those codes are suspected of currentl ...
formulation and evaluation of ibuprofen suppositories
formulation and evaluation of ibuprofen suppositories

... infants and children who have difficulty in swallowing, during nausea and vomiting conditions and when the patient is unconscious1. In addition this route of administration through the use of suppository can also be suitable for local and systemic therapeutic effects2-4. However, in spite being a no ...
Inhibition of Prostaglandin Synthesis and Effects of Ethanol and
Inhibition of Prostaglandin Synthesis and Effects of Ethanol and

... ing (Hale et al., 1992). Overall, these animal studies suggest that some of the effects of ethanol in the brain are due to an increase in prostaglandin synthesis or release and that PGSIs diminish these effects. However, interactions between PGSIs and ethanol in human experiments have yielded mixed ...
Coccidiosis or Coccidiasis?
Coccidiosis or Coccidiasis?

... The anticoccidial drug is changed every 3, 4 or 6 months resulting in 4, 3 or 2 rotations per year. ...
PREPARATION AND UTILITY OF SUB-MICRON LACTOSE, A
PREPARATION AND UTILITY OF SUB-MICRON LACTOSE, A

... improve both the dosing consistency and the drug respirability from the device(1). In MDIs, the requirements for dosing consistency and respirability are still paramount, however the use of bulking agents in the latter systems has never been exploited to any great extent, presumably due to the formu ...
The role of medicine in respiratory diseases
The role of medicine in respiratory diseases

... – Pathological term that describes only one of several structural abnormalities present in patients with COPD ...
NIDA Research Report - Inhalants
NIDA Research Report - Inhalants

... nhalants are volatile substances that produce chemical vapors that can be inhaled to induce a psychoactive, or mind-altering, effect. Although other abused substances can be inhaled, the term “inhalants” is used to describe a variety of substances whose main common characteristic is that they are ra ...
IMPURITIES IN PHARMACEUTICALS
IMPURITIES IN PHARMACEUTICALS

... The specifications for a new substance should include limits for impurities. Stability studies, chemical development studies, and routine batch analyses can be used to predict those impurities likely to occur in the commercial product. The selection of impurities to include in the new substance spec ...
Mock IRAS form - Health Research Authority
Mock IRAS form - Health Research Authority

... The Department of Health’s Research Governance Framework for Health and Social Care and the research  governance frameworks for Wales, Scotland and Northern Ireland set out the requirement for registration of trials.  Furthermore: Article 19 of the World Medical Association Declaration of Helsinki a ...
Metronidazole-containing gel for the treatment of
Metronidazole-containing gel for the treatment of

... product, with therapeutic drug levels established and maintained at the diseased sites for a period that is adequate to suppress microbial activity, with consequent benefit in the treatment of periodontitis.17 The determination of the accurate drug concentration that has to be maintained in the ging ...
Pharmaceutical Innovations and Market Dynamics: Tracking Effects
Pharmaceutical Innovations and Market Dynamics: Tracking Effects

... reason, MAO inhibitors (MAGIs) were taken off the U.S. market for a time. Eventually modified MAOIs were reintroduced, in large part because some depressed patients did not respond to any other medication. Today the MAOIs are used most often when other antidepressant drugs yield unsatisfactory resul ...
RISK MANAGEMENT IN EARLY CLINICAL TRIALS – A CRO
RISK MANAGEMENT IN EARLY CLINICAL TRIALS – A CRO

... © 2016 PAREXEL INTERNATIONAL CORP. / 10 ...
Nitazoxanide (Alinia)  - Texas Medicaid/CHIP Vendor Drug
Nitazoxanide (Alinia) - Texas Medicaid/CHIP Vendor Drug

... comparable in efficacy to vancomycin in treating C. difficile colitis, although current sample sizes are too small to assess clinical significance.8 Nitazoxanide has also shown benefit in treating diarrhea caused by intestinal parasites other than G. lamblia as well as rotavirus, but does not yet po ...
Effects of Social Interaction and Warm Ambient
Effects of Social Interaction and Warm Ambient

... experimental conditions (Baumann et al, 2012; Aarde et al, 2013; Fantegrossi et al, 2013; Merluzzi et al, 2013). Repeated methylone (3–10 mg/kg, subcutaneously (s.c.)) injections increase core temperature in rats (Baumann et al, 2012), but such elevations are less than those induced by MDMA. MDPV is ...
Stribild
Stribild

... occurred during the first 48 weeks. Four (0.6%) subjects who received STRIBILD developed laboratory findings consistent with proximal renal tubular dysfunction, leading to discontinuation of STRIBILD during the first 48 weeks of treatment. Two of the four subjects had renal impairment (i.e., estimat ...
HIGHLIGHTS OF PRESCRIBING INFORMATION -----------------DOSAGE FORMS AND STRENGTHS------
HIGHLIGHTS OF PRESCRIBING INFORMATION -----------------DOSAGE FORMS AND STRENGTHS------

... 25 mg/kg every six hours. This reaction was shown to be reversible when the drug was discontinued. Results of animal studies indicate that tetracyclines cross the placenta, are found in fetal tissues, and can have toxic effects on the developing fetus (often related to retardation of skeletal develo ...
Follow the Script_ Spring 2015
Follow the Script_ Spring 2015

... Methadone is taken orally once every day; it’s inexpensive and is very safe when taken as prescribed. However, it’s a very potent drug and can be harmful if not used properly – even a little too much can be fatal – especially to children. This is why methadone is highly monitored and controlled. Met ...
Abstract: A series of 5-Bromo- 2-formyl phenoxyacetyl and 4
Abstract: A series of 5-Bromo- 2-formyl phenoxyacetyl and 4

... acids and peptides into aromatic and heterocyclic congeners have resulted in compounds with potent bioactivities. Introducing an amino acid or peptide into aromatic compounds can increase the potency, decrease the toxicity and prolong its action. Among aromatics, phenolic compounds have wide range o ...
Methadone
Methadone

... for arrythmia: CHF or other medications that predispose to arrythmia Generally the risk is small and balanced by need for steady pain control ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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