Research Report Series from the director:
... targets for treating cocaine addiction. NIDA remains vigilant in our quest for more effective strategies to address the serious public health issues linked to cocaine abuse. We not only support a wide range of basic and clinical research, but also facilitate the translation of these research finding ...
... targets for treating cocaine addiction. NIDA remains vigilant in our quest for more effective strategies to address the serious public health issues linked to cocaine abuse. We not only support a wide range of basic and clinical research, but also facilitate the translation of these research finding ...
How Marijuana Works article and questions
... inhaled, the THC goes directly to the lungs. Your lungs are lined with millions of alveoli, the tiny air sacs where gas exchange occurs. These alveoli have an enormous surface area -- 90 times greater than that of your skin -- so they make it easy for THC and other compounds to enter the body. The s ...
... inhaled, the THC goes directly to the lungs. Your lungs are lined with millions of alveoli, the tiny air sacs where gas exchange occurs. These alveoli have an enormous surface area -- 90 times greater than that of your skin -- so they make it easy for THC and other compounds to enter the body. The s ...
Changes in antacid use over a 9-year period in a general
... users in this region increased among men from 11.2% to 12.7% (40-49 years) and from 11.9% to 13.4% (5059 years), while the proportion of women using antacids decreased. The proportion of antacid users increased with age in both genders. In the same period, the frequency of self-reported dyspeptic co ...
... users in this region increased among men from 11.2% to 12.7% (40-49 years) and from 11.9% to 13.4% (5059 years), while the proportion of women using antacids decreased. The proportion of antacid users increased with age in both genders. In the same period, the frequency of self-reported dyspeptic co ...
Synthesis of polyphosphazenes with different side
... hybrid organic–inorganic polymers. The main chain of PPZs comprises phosphorous and nitrogen, which are bound with each other through alternating single and double bonds. The most interesting thing in the formation of polyphosphazene is the presence of two chlorine atoms on the phosphorous, as shown ...
... hybrid organic–inorganic polymers. The main chain of PPZs comprises phosphorous and nitrogen, which are bound with each other through alternating single and double bonds. The most interesting thing in the formation of polyphosphazene is the presence of two chlorine atoms on the phosphorous, as shown ...
establishing similarity between multisource betahistine
... into its BCS solubility and permeability classes and we compare the in vitro dosage form performance of IR oral formulation containing BHD against the RLD. Our results provide rational for the interchangeability between the RLD and generic version based on in vitro release profiles. Our results migh ...
... into its BCS solubility and permeability classes and we compare the in vitro dosage form performance of IR oral formulation containing BHD against the RLD. Our results provide rational for the interchangeability between the RLD and generic version based on in vitro release profiles. Our results migh ...
DMSO: Many Uses, Much Controversy
... The history of DMSO as a pharmaceutical began in 1961, when Dr. Jacob was head of the organ transplant program at Oregon Health Sciences University. It all started when he first picked up a bottle of the colorless liquid. While investigating its potential as a preservative for organs, he quickly dis ...
... The history of DMSO as a pharmaceutical began in 1961, when Dr. Jacob was head of the organ transplant program at Oregon Health Sciences University. It all started when he first picked up a bottle of the colorless liquid. While investigating its potential as a preservative for organs, he quickly dis ...
Caffeine, Acting on Adenosine A1 Receptors, Prevents the
... Initiation of Cocaine/Saline Self-Administration. The initial nose-poke activities (in a 10-min trial without infusions) did not differ significantly between the different groups of animals. The mean number of nose-poke responses in the various groups ranged from 23.88 6 14.13 to 31 6 12.87 during 1 ...
... Initiation of Cocaine/Saline Self-Administration. The initial nose-poke activities (in a 10-min trial without infusions) did not differ significantly between the different groups of animals. The mean number of nose-poke responses in the various groups ranged from 23.88 6 14.13 to 31 6 12.87 during 1 ...
13274025
... designed. In the past most drugs have been discovered either by isolating the active ingredient from traditional remedies or by serendipitous discovery. Modern biotechnology often focuses on understanding the metabolic pathways related to a disease state or pathogen, and manipulating these pathways ...
... designed. In the past most drugs have been discovered either by isolating the active ingredient from traditional remedies or by serendipitous discovery. Modern biotechnology often focuses on understanding the metabolic pathways related to a disease state or pathogen, and manipulating these pathways ...
Zentel - FiloBase
... effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38) ...
... effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38) ...
Dow Corning Silicones in Pharmaceutical Applications
... also appeared recently on the market; yet if this eases the handling prior to use (no mixing), these 1-part materials have a very limited shelf life. Some precautions are required with this addition reaction as platinum catalysts can be poisoned by many nucleophilic substances possibly present as co ...
... also appeared recently on the market; yet if this eases the handling prior to use (no mixing), these 1-part materials have a very limited shelf life. Some precautions are required with this addition reaction as platinum catalysts can be poisoned by many nucleophilic substances possibly present as co ...
Bayer Aspirin Complex 500mg/30mg Granules for Oral Suspension
... - renal dysfunction, which may progress to renal failure with oligo-hydroamniosis; the mother and the neonate, at the end of pregnancy, to: - possible prolongation of bleeding time, an anti-aggregating effect which may occur even at very low doses. - inhibition of uterine contractions resulting in d ...
... - renal dysfunction, which may progress to renal failure with oligo-hydroamniosis; the mother and the neonate, at the end of pregnancy, to: - possible prolongation of bleeding time, an anti-aggregating effect which may occur even at very low doses. - inhibition of uterine contractions resulting in d ...
GBL
... >50 patients completed withdrawal 1. Patients NOT socially excluded - mostly employed, educated, and with no other drug dependence 2. Erratically compliance - people don’t answer calls, cancel appointments, and appear to think that they are managing their own lives 3. Many relapsed, weeks to months ...
... >50 patients completed withdrawal 1. Patients NOT socially excluded - mostly employed, educated, and with no other drug dependence 2. Erratically compliance - people don’t answer calls, cancel appointments, and appear to think that they are managing their own lives 3. Many relapsed, weeks to months ...
JAP Mar. 86/3 - Journal of Applied Physiology
... ANTITUSSIVE DRUGS, such as codeine and dextromethorphan, are among the most commonly used prescription and over-the-counter drugs in the world (12). These drugs are broadly classified into two groups based on their site of action: peripheral or central. Peripheral antitussive drugs act outside the c ...
... ANTITUSSIVE DRUGS, such as codeine and dextromethorphan, are among the most commonly used prescription and over-the-counter drugs in the world (12). These drugs are broadly classified into two groups based on their site of action: peripheral or central. Peripheral antitussive drugs act outside the c ...
M7 Step 4 Assessment and control of DNA reactive (mutagenic
... impurity limits include a significant increase in clinical dose, an increase in duration of use (in particular when a mutagenic impurity was controlled above the lifetime acceptable intake for a previous indication that may no longer be appropriate for the longer treatment duration associated with t ...
... impurity limits include a significant increase in clinical dose, an increase in duration of use (in particular when a mutagenic impurity was controlled above the lifetime acceptable intake for a previous indication that may no longer be appropriate for the longer treatment duration associated with t ...
Preview the material
... by which alcohol and these drugs cause a substance use disorder and the withdrawal syndromes associated with each one will be discussed in separate sections. Alcohol Aside from tobacco, alcohol is the most commonly used psychoactive drug in our society. There are many types of alcohol, i.e., ethylen ...
... by which alcohol and these drugs cause a substance use disorder and the withdrawal syndromes associated with each one will be discussed in separate sections. Alcohol Aside from tobacco, alcohol is the most commonly used psychoactive drug in our society. There are many types of alcohol, i.e., ethylen ...
Available Online through - International Journal of Pharmacy and
... and 100 mg/disc) mild antibacterial property is observed on these organisms. At 100 mg/disc dose embelin reported more diameter of zone of inhibition than standard (kanamycin) used at 39 mg/disc when tested against Staphylococcus aureus, Shigella flexneri and Shigella sonnei . Same kind of response ...
... and 100 mg/disc) mild antibacterial property is observed on these organisms. At 100 mg/disc dose embelin reported more diameter of zone of inhibition than standard (kanamycin) used at 39 mg/disc when tested against Staphylococcus aureus, Shigella flexneri and Shigella sonnei . Same kind of response ...
Comparison of Pharmacokinetic and Pharmacodynamic Effects of
... about the total amount of drug deposited in the lungs, pulmonary residence time, and systemic exposure; and are able to detect differences between two formulations [18,19]. There is limited published data describing the extent of first pass metabolism of inhaled salmeterol [20,21]. The differences b ...
... about the total amount of drug deposited in the lungs, pulmonary residence time, and systemic exposure; and are able to detect differences between two formulations [18,19]. There is limited published data describing the extent of first pass metabolism of inhaled salmeterol [20,21]. The differences b ...
Limitations - HAL
... model 2 was further adjusted for pathologies associated with anticholinergic drug use in order to take into account a possible prescription bias, e.g. depression, ischemic pathologies, Parkinson’s disease, and hypertension. For analyses taking into account number of anticholinergic medications we us ...
... model 2 was further adjusted for pathologies associated with anticholinergic drug use in order to take into account a possible prescription bias, e.g. depression, ischemic pathologies, Parkinson’s disease, and hypertension. For analyses taking into account number of anticholinergic medications we us ...
Suppositories and Inserts
... Determine the average weight per mold (blank) using the suppository base of interest Weigh the quantity of suppository base necessary for 10 suppositories Divide the density of the active drug by the density of the suppository base to obtain a ratio Divide the total weight of active drug required fo ...
... Determine the average weight per mold (blank) using the suppository base of interest Weigh the quantity of suppository base necessary for 10 suppositories Divide the density of the active drug by the density of the suppository base to obtain a ratio Divide the total weight of active drug required fo ...
Center for Medicinal Cannabis Research
... By design CMCR clinical studies focused on conditions identified by the Institute of Medicine for which cannabis might have potential therapeutic effects, based on current scientific knowledge (Institute of Medicine, 1999). To date, four CMCR-funded studies have demonstrated that cannabis has analge ...
... By design CMCR clinical studies focused on conditions identified by the Institute of Medicine for which cannabis might have potential therapeutic effects, based on current scientific knowledge (Institute of Medicine, 1999). To date, four CMCR-funded studies have demonstrated that cannabis has analge ...
090-14 Medicines Policy - London North West Healthcare NHS Trust
... The procedures are filed in sections relating to specific functions. Each section can be easily identified by the section dividers. Significant changes may be made when the policy is next reviewed. Always ensure you refer to the most recent version. Feedback on the Policy to ensure it reflects curre ...
... The procedures are filed in sections relating to specific functions. Each section can be easily identified by the section dividers. Significant changes may be made when the policy is next reviewed. Always ensure you refer to the most recent version. Feedback on the Policy to ensure it reflects curre ...
YDRAZINE SULF ATE B. Chemical Name: C. Common Name:
... Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Antidote: No specific antidote exists. **+* CJECTION 5 _ FIRE FIGHTING ...
... Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Antidote: No specific antidote exists. **+* CJECTION 5 _ FIRE FIGHTING ...
Nasal Route: A Potential Alternative for Antiparkinsonism Drug
... increasing the residence time of drug in the nasal mucosa and also by using mucoadhesive polymers. In this manner it is possible to efficiently deliver challenging drugs such as low molecular weight polar molecules, antiparkinsonism drugs and macromolecular polysaccharides. This review emphasizes on ...
... increasing the residence time of drug in the nasal mucosa and also by using mucoadhesive polymers. In this manner it is possible to efficiently deliver challenging drugs such as low molecular weight polar molecules, antiparkinsonism drugs and macromolecular polysaccharides. This review emphasizes on ...
Learning Checklist
... Describe the effects of cannabis Explain why the use of legal drugs has a greater impact on health than the use of illegal drugs Evaluate the impact of different types of drugs on society Put drugs into various categories, eg narcotic, stimulants, hallucinogens, Describe ways in which some recreatio ...
... Describe the effects of cannabis Explain why the use of legal drugs has a greater impact on health than the use of illegal drugs Evaluate the impact of different types of drugs on society Put drugs into various categories, eg narcotic, stimulants, hallucinogens, Describe ways in which some recreatio ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.