Hard Shell Capsules
... shell capsule filling machines have the same operational steps in common: rectification, capsule separation, filling, closure of the capsule, and ejection of the filled and closed capsule from the machine. Rectification is a mechanical process that causes the empty capsules to be lined up all in the ...
... shell capsule filling machines have the same operational steps in common: rectification, capsule separation, filling, closure of the capsule, and ejection of the filled and closed capsule from the machine. Rectification is a mechanical process that causes the empty capsules to be lined up all in the ...
Bioisosterism: A Rational Approach in Drug Design
... The widespread application of the concept of isosterism to modify biological activity has given rise to the term bioisosterism. As initially defined by Friedman,2 bioisosteres were to include all atoms and molecules which fit the broadest definition for isosteres and have a similar type of biologica ...
... The widespread application of the concept of isosterism to modify biological activity has given rise to the term bioisosterism. As initially defined by Friedman,2 bioisosteres were to include all atoms and molecules which fit the broadest definition for isosteres and have a similar type of biologica ...
MDMA powder
... such as lasers are often highly synergistic with the drug. The psychedelic amphetamine quality of MDMA lends it to variable reasons as to why it appeals to users in the "rave" setting. Some users enjoy the feeling of mass communion from the inhibition-depressing effects of the drug, while others use ...
... such as lasers are often highly synergistic with the drug. The psychedelic amphetamine quality of MDMA lends it to variable reasons as to why it appeals to users in the "rave" setting. Some users enjoy the feeling of mass communion from the inhibition-depressing effects of the drug, while others use ...
Marijuana as a Schedule I Substance: Political Ploy or Accepted
... The Institute of Medicine ("IOM") was "chartered in 1970 by the National Academy of Sciences to enlist distinguished members of the appropriate professions in the examination of policy matters pertaining to the health of the public." 75 The institute's 1999 report, Marijuana and Medicine: Assessing ...
... The Institute of Medicine ("IOM") was "chartered in 1970 by the National Academy of Sciences to enlist distinguished members of the appropriate professions in the examination of policy matters pertaining to the health of the public." 75 The institute's 1999 report, Marijuana and Medicine: Assessing ...
opioid codrugs for pain management - UKnowledge
... given to all outside sources. I understand that I am solely responsible for obtaining any needed copyright permissions. I have obtained and attached hereto needed written permission statements(s) from the owner(s) of each third-party copyrighted matter to be included in my work, allowing electronic ...
... given to all outside sources. I understand that I am solely responsible for obtaining any needed copyright permissions. I have obtained and attached hereto needed written permission statements(s) from the owner(s) of each third-party copyrighted matter to be included in my work, allowing electronic ...
6 points each
... would be predicted to be 1740 L (1000 L * 121.4 kg/70 kg). The total amount of drug in the body thus appears to be: 1.238 mg/L * 1740 L = ~2154 mg. This represents a high amount. The cause of death was probably due to toxic effects of olanzapine. The PDR states that accidental ingestion of 300 mg of ...
... would be predicted to be 1740 L (1000 L * 121.4 kg/70 kg). The total amount of drug in the body thus appears to be: 1.238 mg/L * 1740 L = ~2154 mg. This represents a high amount. The cause of death was probably due to toxic effects of olanzapine. The PDR states that accidental ingestion of 300 mg of ...
Safe Handling of Cytotoxics
... of parenteral cytotoxics by health care workers. The objective of this update is: to update and address new issues in cytotoxic handling that have developed since the previous guideline, including the use of oral cytotoxics, selection and use of personal protective equipment, and treatment in divers ...
... of parenteral cytotoxics by health care workers. The objective of this update is: to update and address new issues in cytotoxic handling that have developed since the previous guideline, including the use of oral cytotoxics, selection and use of personal protective equipment, and treatment in divers ...
Full Product Information
... Special Warnings and Special Precautions for Use Hematologic Effects Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, granulocytopenia, and bone marrow depression) are known to occur after the administration of chloramphenicol. (See section 4.8 Undesirable E ...
... Special Warnings and Special Precautions for Use Hematologic Effects Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, granulocytopenia, and bone marrow depression) are known to occur after the administration of chloramphenicol. (See section 4.8 Undesirable E ...
Prevention Guide - Safe Handling of Hazardous Drugs
... and institutions through consulting services, as well as through information, training and research and development activities, to implement preventive measures designed to: – identify and eliminate health and safety hazards at the source, in order to preserve the physical and psychological integrit ...
... and institutions through consulting services, as well as through information, training and research and development activities, to implement preventive measures designed to: – identify and eliminate health and safety hazards at the source, in order to preserve the physical and psychological integrit ...
DEPLETION OF SOMATOSTATIN-LIKE IMMUNOREACTIVITY IN
... This general pattern was confirmed in a repeat experiment (data not shown), with the cervical spinal cord being the most affected of the regions examined, the cerebral cortex the least, and other regions being intermediate in degree. The hippocampus was examined in a single experiment in which SLI w ...
... This general pattern was confirmed in a repeat experiment (data not shown), with the cervical spinal cord being the most affected of the regions examined, the cerebral cortex the least, and other regions being intermediate in degree. The hippocampus was examined in a single experiment in which SLI w ...
Evaluation of potential retinal toxicity of adalimumab (Humira)
... Intravitreal injections have emerged during the last years as a new very effective way for delivering therapeutic agents intraocularly [23–25], ameliorating the possible systemic effects of such agents. However, intravitreal administration poses also risks related both to the procedure of administra ...
... Intravitreal injections have emerged during the last years as a new very effective way for delivering therapeutic agents intraocularly [23–25], ameliorating the possible systemic effects of such agents. However, intravitreal administration poses also risks related both to the procedure of administra ...
Running head: FACTORS THAT INFLUENCE
... participate in the process of forming a treatment regiment. This bilateral relationship between clinicians and patients gives patients a greater say in their care. Along with changes in the patient-clinician relationship, patients also have the opportunity to acquire a great amount of medical inform ...
... participate in the process of forming a treatment regiment. This bilateral relationship between clinicians and patients gives patients a greater say in their care. Along with changes in the patient-clinician relationship, patients also have the opportunity to acquire a great amount of medical inform ...
Shenyang Pharmaceutical University LAB 10: LIPOSOMES
... microns in diameter and show a multi-compartmental structure (under a microscope) which is similar to the cross-sectional appearance of an onion or a human fingerprint. There are a variety of methods applicable for preparing liposomes. (a) The thin-film dispersion method. This is the most commonly u ...
... microns in diameter and show a multi-compartmental structure (under a microscope) which is similar to the cross-sectional appearance of an onion or a human fingerprint. There are a variety of methods applicable for preparing liposomes. (a) The thin-film dispersion method. This is the most commonly u ...
PIRACETAM ñ AN OLD DRUG WITH NOVEL PROPERTIES?
... inhibitors, tricyclic antidepressants, or amphetamines. It was found that piracetam instead facilitates interhemispheric transfer, enhances the cerebral resistance to noxious stimuli like hypoxia and improves learning and other cognitive functions under normal conditions (13, 14). However, the impro ...
... inhibitors, tricyclic antidepressants, or amphetamines. It was found that piracetam instead facilitates interhemispheric transfer, enhances the cerebral resistance to noxious stimuli like hypoxia and improves learning and other cognitive functions under normal conditions (13, 14). However, the impro ...
MDMA (Ecstasy) - cloudfront.net
... rare but largely unpredictable occasions, this has led to severe medical consequences, including death.3,4 Also, MDMA causes the release of another neurotransmitter, norepinephrine, which is likely the cause of the increase in heart rate and blood pressure that often accompanies MDMA use.5,6 ...
... rare but largely unpredictable occasions, this has led to severe medical consequences, including death.3,4 Also, MDMA causes the release of another neurotransmitter, norepinephrine, which is likely the cause of the increase in heart rate and blood pressure that often accompanies MDMA use.5,6 ...
Vaccinium myrtillus (Bilberry) | (HE 1:1 | 42-85ml)
... and platelet activation (35455). Similarly, in in vitro studies, anthocyanins extracted from bilberry inhibited platelet aggregation (35478, 35505, 35502, 35504). Flavonoids have been shown in vitro to inhibit prostacyclin synthesis. In one animal model, Vaccinium myrtillus anthocyanosides were stud ...
... and platelet activation (35455). Similarly, in in vitro studies, anthocyanins extracted from bilberry inhibited platelet aggregation (35478, 35505, 35502, 35504). Flavonoids have been shown in vitro to inhibit prostacyclin synthesis. In one animal model, Vaccinium myrtillus anthocyanosides were stud ...
قسم الصيدلة السريرية
... 7- Interactions of drugs and their significance in treatment and the different mechanisms of possible drug interactions. 8-The concepts related to the industrial pharmacy starting from the raw materials and ending with the finished product in the market. 9- Good manufacturing practice (GMP) of pharm ...
... 7- Interactions of drugs and their significance in treatment and the different mechanisms of possible drug interactions. 8-The concepts related to the industrial pharmacy starting from the raw materials and ending with the finished product in the market. 9- Good manufacturing practice (GMP) of pharm ...
Overcoming the Stratum Corneum: The Modulation of Skin Penetration
... 1980s. They can be used as penetration enhancers for hydrophilic and lipophilic substances and for peptide molecules as well, e.g. insulin and vasopressin. Interestingly, Azone and derivatives are effective penetration enhancers when used in low concentrations (1–5%). Their activity can be increased ...
... 1980s. They can be used as penetration enhancers for hydrophilic and lipophilic substances and for peptide molecules as well, e.g. insulin and vasopressin. Interestingly, Azone and derivatives are effective penetration enhancers when used in low concentrations (1–5%). Their activity can be increased ...
Mexican plants with hypoglycaemic effect used in the treatment of
... are diagnosed in one of the primary health care centres and the MDs in these centres normally also prescribe appropriate medication. However, once a diagnosis is made the patients often recur to either local healers or to vendors of herbal and other health care products. Thus this is a disease for w ...
... are diagnosed in one of the primary health care centres and the MDs in these centres normally also prescribe appropriate medication. However, once a diagnosis is made the patients often recur to either local healers or to vendors of herbal and other health care products. Thus this is a disease for w ...
Cytochrome P450 and Chemical Toxicology
... become covalently bound to proteins and DNA. With drugs, there are examples in which a drug metabolite may have more intrinsic activity with a receptor than the parent compound (81), but obvious examples related to toxicity are not available (82). A strong case exists that binding of electrophiles t ...
... become covalently bound to proteins and DNA. With drugs, there are examples in which a drug metabolite may have more intrinsic activity with a receptor than the parent compound (81), but obvious examples related to toxicity are not available (82). A strong case exists that binding of electrophiles t ...
Absorption, Metabolism, and Excretion of Paliperidone, a New
... solution with a total radioactivity of ⬃16 Ci, along with 200 ml of water. Sample Collections. Blood samples (⬃10 ml) were obtained before dosing and at 0.5, 1, 1.5, 3, 6, 12, 16, 36, 48, 72, 96, 120, 144, and 168 h after dosing. In addition, ⬃20 ml of blood for the purpose of metabolite profiling ...
... solution with a total radioactivity of ⬃16 Ci, along with 200 ml of water. Sample Collections. Blood samples (⬃10 ml) were obtained before dosing and at 0.5, 1, 1.5, 3, 6, 12, 16, 36, 48, 72, 96, 120, 144, and 168 h after dosing. In addition, ⬃20 ml of blood for the purpose of metabolite profiling ...
Design of Drug Delivery Methods for the Brain and Central
... Jeonghwa, Minh, Jacek, Joe, and Tejen. They provided valuable suggestions and critical reviews of my work especially during group meetings and private discussions. I would like to acknowledge the invaluable support Indu, Joe, and Tejen provided me with in the intrathecal magnetic drug targeting rese ...
... Jeonghwa, Minh, Jacek, Joe, and Tejen. They provided valuable suggestions and critical reviews of my work especially during group meetings and private discussions. I would like to acknowledge the invaluable support Indu, Joe, and Tejen provided me with in the intrathecal magnetic drug targeting rese ...
Stinging Nettle: the Bad, the Good, the Unknown
... possesses a number of potentially beneficial anti-inflammatory and modulating properties, beneficial effects have often not been confirmed by well-designed clinical trials. Further study, perhaps with novel types of extracts, are needed to determine the clinical utility of this plant in human inflam ...
... possesses a number of potentially beneficial anti-inflammatory and modulating properties, beneficial effects have often not been confirmed by well-designed clinical trials. Further study, perhaps with novel types of extracts, are needed to determine the clinical utility of this plant in human inflam ...
Pharmacology and the Nursing Process, 4th ed
... Mosby items and derived items © 2007, 2005, 2002 by Mosby, Inc., an affiliate of Elsevier Inc. ...
... Mosby items and derived items © 2007, 2005, 2002 by Mosby, Inc., an affiliate of Elsevier Inc. ...
Antipsychotic drugs reverse the AMPA receptor-stimulated release
... Surgery and microdialysis experiments An updated description of the microdialysis procedures used can be found in Adell and Artigas (1998) and Puig et al. (2003). Briefly, anesthetized rats (sodium pentobarbital, 60 mg/kg i.p.) were stereotaxically implanted with concentric microdialysis probes equi ...
... Surgery and microdialysis experiments An updated description of the microdialysis procedures used can be found in Adell and Artigas (1998) and Puig et al. (2003). Briefly, anesthetized rats (sodium pentobarbital, 60 mg/kg i.p.) were stereotaxically implanted with concentric microdialysis probes equi ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.