September 2015 - State Pharmaceuticals Corporation of Sri Lanka
... Management of osteoarthritis should be based on a combination of non-drug and drug treatments targeted towards prevention, modifying risk and disease progression. Obesity is the most important modifiable risk factor, so losing weight in addition to land- and water-based exercise and strength trainin ...
... Management of osteoarthritis should be based on a combination of non-drug and drug treatments targeted towards prevention, modifying risk and disease progression. Obesity is the most important modifiable risk factor, so losing weight in addition to land- and water-based exercise and strength trainin ...
Protocol S1.
... Several approaches are currently being utilized to control and tailor protein glycosylation in plants, including specific targeting to subcellular compartments and the genetic modification of glycosylation machinery. As mention above, when human glucocerebrosidase is produced in mammalian cell cultu ...
... Several approaches are currently being utilized to control and tailor protein glycosylation in plants, including specific targeting to subcellular compartments and the genetic modification of glycosylation machinery. As mention above, when human glucocerebrosidase is produced in mammalian cell cultu ...
H.M. Garraffo, T.F. Spande, M. Williams, Heterocycles, 79, (2009)
... Scientific research is a far from predictable process with serendipity playing a key role in major discoveries27 despite the current day reductionistic focus on molecular mechanisms. In this regard, the continued role of the basic research funded by the intramural programs at the NIH remains an inva ...
... Scientific research is a far from predictable process with serendipity playing a key role in major discoveries27 despite the current day reductionistic focus on molecular mechanisms. In this regard, the continued role of the basic research funded by the intramural programs at the NIH remains an inva ...
The Frequency of Sister Chromatid Exchanges in Cultured Human
... mL dose of MTZ. The data obtained from the current study reflect that MTZ has cytostatic and cytotoxic properties and produces genotoxic effects in human peripheral blood lymphocyte cultures in vitro. These results indicate that there is a strong interaction between metronidazole and DNA at concentr ...
... mL dose of MTZ. The data obtained from the current study reflect that MTZ has cytostatic and cytotoxic properties and produces genotoxic effects in human peripheral blood lymphocyte cultures in vitro. These results indicate that there is a strong interaction between metronidazole and DNA at concentr ...
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCHES OF ONDANSETRON HYDROCHLORIDE Research Article
... method was found to give thin uniform patches. Ex vivo permeation studies of formulations were performed by using Franz diffusion cells. It was observed that the formulation B3 shows better extended release up to 12 hrs and followed Korsmeyers–Peppas model in dissolution study. The release rate foun ...
... method was found to give thin uniform patches. Ex vivo permeation studies of formulations were performed by using Franz diffusion cells. It was observed that the formulation B3 shows better extended release up to 12 hrs and followed Korsmeyers–Peppas model in dissolution study. The release rate foun ...
History of Doping in Sport
... physicians willing to test them. In addition, various laboratories, including some in the United States such as the New York Pasteur Institute, began preparing the extract for use (Borell, 1976). This began a swell of experiments not only in France but throughout the Western world employing testicul ...
... physicians willing to test them. In addition, various laboratories, including some in the United States such as the New York Pasteur Institute, began preparing the extract for use (Borell, 1976). This began a swell of experiments not only in France but throughout the Western world employing testicul ...
Relative Reinforcing Effects of Cocaine, Remifentanil, and Their
... heroin in combination. The isobolographic analysis demonstrated that two of the drug combinations produced less reinforcing effect than would be expected by a simple addition of drug effects. One combination ratio (3.2 cocaine:1.0 heroin) produced the same reinforcing effect as would be anticipated ...
... heroin in combination. The isobolographic analysis demonstrated that two of the drug combinations produced less reinforcing effect than would be expected by a simple addition of drug effects. One combination ratio (3.2 cocaine:1.0 heroin) produced the same reinforcing effect as would be anticipated ...
Attachment A--Common Drugs Used for Laboratory Animals
... Attachment A--Common Drugs Used for Laboratory Animals Please note: The safe and effective use of any anesthetic agent requires knowledge and experience in anesthesiology. The veterinarians are available to help with choices of anesthetics, analgesics, or tranquilizers that are most appropriate for ...
... Attachment A--Common Drugs Used for Laboratory Animals Please note: The safe and effective use of any anesthetic agent requires knowledge and experience in anesthesiology. The veterinarians are available to help with choices of anesthetics, analgesics, or tranquilizers that are most appropriate for ...
Solid dosage forms
... coatings so that various portions of the drug will dissolve at different rates. They are designed to produce drug effects over an extended time. SR tablets are administered less frequently (usually once daily). e.g. Isoptin SR, Ravel SR ...
... coatings so that various portions of the drug will dissolve at different rates. They are designed to produce drug effects over an extended time. SR tablets are administered less frequently (usually once daily). e.g. Isoptin SR, Ravel SR ...
Psychometric assessment of the Hallucinogen Rating Scale Drug Alcohol Depend 137
... effects on the central nervous system. By measuring the mood-, perception- and cognition-altering effects that are characteristic of a given drug, these instruments can help characterize their activity profiles over time and establish dose-response data. Although neuroendocrine and neurophysiologica ...
... effects on the central nervous system. By measuring the mood-, perception- and cognition-altering effects that are characteristic of a given drug, these instruments can help characterize their activity profiles over time and establish dose-response data. Although neuroendocrine and neurophysiologica ...
Slide 1
... becomes more brittle with abrupt swings between hyper- and hypomobility (the on-off phenomenon). In this case a more effective approach is to use a COMT inhibitor, e.g. entacapone, which can sometimes allay early end-of-dose deterioration without causing dyskinesia. Some 20% of the patients with Par ...
... becomes more brittle with abrupt swings between hyper- and hypomobility (the on-off phenomenon). In this case a more effective approach is to use a COMT inhibitor, e.g. entacapone, which can sometimes allay early end-of-dose deterioration without causing dyskinesia. Some 20% of the patients with Par ...
A KROKODIL BITE ME…I WASN’T IN THE WATER (IT WAS A …
... caustic drug causes an addict's skin to become green, scaly and bumpy like a crocodile's. If the drug misses a vein and is injected into flesh, that flesh will develop abscesses. It is common for addicts to develop gangrene and require amputations. The flesh on some body parts affected by krokodil i ...
... caustic drug causes an addict's skin to become green, scaly and bumpy like a crocodile's. If the drug misses a vein and is injected into flesh, that flesh will develop abscesses. It is common for addicts to develop gangrene and require amputations. The flesh on some body parts affected by krokodil i ...
effect of trikatu, an ayurvedic prescription, on the pharmacokinetic
... metabolism. J Pharmacal Exp Ther 1985; 232: 258262. Singh J. Dubey RK, Atal CK, Piperine mediated inhibition of glucuronidation activity in isolated ...
... metabolism. J Pharmacal Exp Ther 1985; 232: 258262. Singh J. Dubey RK, Atal CK, Piperine mediated inhibition of glucuronidation activity in isolated ...
Willow Bark - Learnblock
... • Analgesia may be slower to develop with herbal products • when the effect is less than expected with pharmaceuticals for severe cases, administration with low dose of NSAIDs – may further alleviate pain – may reduce the need of patient for NSAIDs – may be cost effective ...
... • Analgesia may be slower to develop with herbal products • when the effect is less than expected with pharmaceuticals for severe cases, administration with low dose of NSAIDs – may further alleviate pain – may reduce the need of patient for NSAIDs – may be cost effective ...
NIH Public Access
... Fig. S1: WDLS/DDLS tumors and the two cell lines used in this study have complex DNA copy number alterations. Fig. S2: EC50 determination using a cell metabolic activity assay shows good agreement between biological replicates. Fig. S3: Effects of PD0332991 and NVP-AEW541 in DDLS8817 and LPS141 cell ...
... Fig. S1: WDLS/DDLS tumors and the two cell lines used in this study have complex DNA copy number alterations. Fig. S2: EC50 determination using a cell metabolic activity assay shows good agreement between biological replicates. Fig. S3: Effects of PD0332991 and NVP-AEW541 in DDLS8817 and LPS141 cell ...
Effects of Citicholine on respiration rate, Spo2, heart rate
... slight drop in the body temperature was seen though it was, when compared with the body temperature of experimental group, very trivial. These findings have not so far been reported in any scientific sources and their explanation needs more researches on the pharmacokinetics of this drug as well as ...
... slight drop in the body temperature was seen though it was, when compared with the body temperature of experimental group, very trivial. These findings have not so far been reported in any scientific sources and their explanation needs more researches on the pharmacokinetics of this drug as well as ...
Duration of action
... • E- Rapidity of onset : ideally the injection of such an agent should be followed immediately by the onset of local anesthesia , experiments have shown that the mean onset time following infiltration anesthesia using 2% lignocaine with 1:80:000 adrenaline solution is about 1 minute 20 seconds . • ...
... • E- Rapidity of onset : ideally the injection of such an agent should be followed immediately by the onset of local anesthesia , experiments have shown that the mean onset time following infiltration anesthesia using 2% lignocaine with 1:80:000 adrenaline solution is about 1 minute 20 seconds . • ...
Formulary Updates Volume 13, Issue 3 · March 2015
... The following medications were removed from the formulary and are no longer subsidized: Moxifloxacin (Avelox) - ciprofloxacin and levofloxacin are available alternatives. UHS pharmacies participate in the 340B drug pricing program and must comply with program requirements. ...
... The following medications were removed from the formulary and are no longer subsidized: Moxifloxacin (Avelox) - ciprofloxacin and levofloxacin are available alternatives. UHS pharmacies participate in the 340B drug pricing program and must comply with program requirements. ...
PROCEEDINGS FROM THE ISMP SUMMIT ON THE USE OF SMART INFUSION PUMPS:
... Intravenous infusion pumps are used to deliver parenteral medications at precise rates or in specific amounts. This technology is not new, but for several years, infusion pumps have been manufactured with software that can alert users to potential errors. The pumps with this additional software are ...
... Intravenous infusion pumps are used to deliver parenteral medications at precise rates or in specific amounts. This technology is not new, but for several years, infusion pumps have been manufactured with software that can alert users to potential errors. The pumps with this additional software are ...
Inhaled Microparticles Containing Clofazimine Are Efficacious in
... rifabutin (INH-RFB) for comparison formed part of the experiment. Treatment started 21 days postinfection, with doses in all treatment groups administered twice per week for 4 weeks (total of 8 doses). CFM was administered orally by gavage as a suspension in soybean oil at dose levels of 5, 10, and ...
... rifabutin (INH-RFB) for comparison formed part of the experiment. Treatment started 21 days postinfection, with doses in all treatment groups administered twice per week for 4 weeks (total of 8 doses). CFM was administered orally by gavage as a suspension in soybean oil at dose levels of 5, 10, and ...
Fludrocortisone for low blood pressure on standing (postur
... syndrome', another form of hormone imbalance. Fludrocortisone is also used to raise blood pressure in people with postural hypotension, but it does not have a UK licence for this, and so its use to treat postural hypotension is called 'off-label'. It raises blood pressure by increasing sodium (salt) ...
... syndrome', another form of hormone imbalance. Fludrocortisone is also used to raise blood pressure in people with postural hypotension, but it does not have a UK licence for this, and so its use to treat postural hypotension is called 'off-label'. It raises blood pressure by increasing sodium (salt) ...
Sedative-Hypnotic Drugs
... ¾ "R" labels denote common locations of side chains, which give different benzodiazepines their unique properties. ...
... ¾ "R" labels denote common locations of side chains, which give different benzodiazepines their unique properties. ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... Acute toxicity test(7,8):It was conducted in mice using ondansetron intraperitonially(i.p) in the dosage of 8,16,32 and 64mg/kg body weight.LD50 was found to be 46mg/kg body weight. According to the known literature LD50 of aspirin when given Intraperitonially in mice is 160mg/kg body weight. Chemic ...
... Acute toxicity test(7,8):It was conducted in mice using ondansetron intraperitonially(i.p) in the dosage of 8,16,32 and 64mg/kg body weight.LD50 was found to be 46mg/kg body weight. According to the known literature LD50 of aspirin when given Intraperitonially in mice is 160mg/kg body weight. Chemic ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.