pdf file
... formally analysed ambient multi-agent system model for the domain of medicine usage management is presented. The main problem addressed in this health domain is to achieve in a non-intrusive, human-like manner that patients for whom it is crucial that they take medicine regularly, indeed do so. Exam ...
... formally analysed ambient multi-agent system model for the domain of medicine usage management is presented. The main problem addressed in this health domain is to achieve in a non-intrusive, human-like manner that patients for whom it is crucial that they take medicine regularly, indeed do so. Exam ...
Clinical and experimental studies on theophylline
... and COPD, and newer uses emerging • Steroids are the first line of drugs for asthma but are given along with bronchodilators like theophylline to reduce their dosage and reverse steroid resistance • Theophylline is an effective, pharmacoeconomically viable drug, but has a narrow therapeutic index, i ...
... and COPD, and newer uses emerging • Steroids are the first line of drugs for asthma but are given along with bronchodilators like theophylline to reduce their dosage and reverse steroid resistance • Theophylline is an effective, pharmacoeconomically viable drug, but has a narrow therapeutic index, i ...
Antiviral Agents: Structural Basis of Action and Rational Design
... example, in the case of influenza virus) or the fusion of the cellular membrane with the viral envelope, as demonstrated in the case of retroviruses (see Chap. 16). These events allow the internalization of the capsid containing the viral genome. Uncoating or disassembly is a still poorly understood ...
... example, in the case of influenza virus) or the fusion of the cellular membrane with the viral envelope, as demonstrated in the case of retroviruses (see Chap. 16). These events allow the internalization of the capsid containing the viral genome. Uncoating or disassembly is a still poorly understood ...
Drugs used in the management of hyperlipidemia
... It’s a vascular disease characterized by patchy subintimal thickening of medium and large arteries which can reduce or obstruct blood flow. The pathogenesis of atheriosclerosis is, as yet, far from completely elucidated and, indeed, within the LDL particles themselves, there is a structural heteroge ...
... It’s a vascular disease characterized by patchy subintimal thickening of medium and large arteries which can reduce or obstruct blood flow. The pathogenesis of atheriosclerosis is, as yet, far from completely elucidated and, indeed, within the LDL particles themselves, there is a structural heteroge ...
Average, population and individual bioequivalence
... Debate around generic drugs efficacy and safety is not a recent issue. In the very beginning of the last century, the US Congress approved the Biologics Control Act – dating from July 1st 1902, it established the need for annual licensing of companies that manufactured and sold vaccines and serum de ...
... Debate around generic drugs efficacy and safety is not a recent issue. In the very beginning of the last century, the US Congress approved the Biologics Control Act – dating from July 1st 1902, it established the need for annual licensing of companies that manufactured and sold vaccines and serum de ...
INFINITY PHARMACEUTICALS, INC.
... Infinity will host a conference call on Tuesday, May 7, 2013, at 4:30 p.m. EDT to discuss these financial results and provide an update on the company. A live webcast of the conference call can be accessed in the “investors/media” section of Infinity’s website at www.infi.com. To participate in the ...
... Infinity will host a conference call on Tuesday, May 7, 2013, at 4:30 p.m. EDT to discuss these financial results and provide an update on the company. A live webcast of the conference call can be accessed in the “investors/media” section of Infinity’s website at www.infi.com. To participate in the ...
Garcinia - Apothecary Remedies (India) Inc.
... feeding. Consult a doctor before giving it to children. You may also want to avoid HCA if you suffer from migraine or arthritis which can be worsened by citrus fruits. HCA has some significant advantages over many other weight loss supplements ingredients because it has been extensively tested in re ...
... feeding. Consult a doctor before giving it to children. You may also want to avoid HCA if you suffer from migraine or arthritis which can be worsened by citrus fruits. HCA has some significant advantages over many other weight loss supplements ingredients because it has been extensively tested in re ...
PET Imaging: Scenarios to illustrate regulatory issues
... “Specials” licence would allow the study investigators to demonstrate manufacture of AV45 to GMP and the physician in charge of the trial could request its use under such a licence. Although with AD patients the “Specials” licence should be applicable, the use of a “Specials” licence in relation to ...
... “Specials” licence would allow the study investigators to demonstrate manufacture of AV45 to GMP and the physician in charge of the trial could request its use under such a licence. Although with AD patients the “Specials” licence should be applicable, the use of a “Specials” licence in relation to ...
The Development of New Therapeutics for Alzheimerʼns Disease
... for Alzheimer’s Disease MD Carter1, GA Simms1 and DF Weaver1,2,3 Existing treatments for Alzheimer’s disease (AD) fail to address the underlying pathology of the disease; they merely provide short-lived symptomatic relief. Consequently, the progression of AD is unrelenting, leading to a continual de ...
... for Alzheimer’s Disease MD Carter1, GA Simms1 and DF Weaver1,2,3 Existing treatments for Alzheimer’s disease (AD) fail to address the underlying pathology of the disease; they merely provide short-lived symptomatic relief. Consequently, the progression of AD is unrelenting, leading to a continual de ...
Guideline on the investigation of bioequivalence - EMA
... Conduct of a multiple dose study in patients is acceptable if a single dose study cannot be conducted in healthy volunteers due to tolerability reasons, and a single dose study is not feasible in patients. In the rare situation where problems of sensitivity of the analytical method preclude sufficie ...
... Conduct of a multiple dose study in patients is acceptable if a single dose study cannot be conducted in healthy volunteers due to tolerability reasons, and a single dose study is not feasible in patients. In the rare situation where problems of sensitivity of the analytical method preclude sufficie ...
Hydroxyurea - Thalassemia Dubai
... Evidence for efficacy of hydroxyurea in children with sickle cell disease is encouraging but is not as strong as in adults. ...
... Evidence for efficacy of hydroxyurea in children with sickle cell disease is encouraging but is not as strong as in adults. ...
Atropine Sulfate Ampoule Product Sheet (PDF
... Administration of this product under strict medical supervision. ...
... Administration of this product under strict medical supervision. ...
Definitions and Concepts
... Generic product with that of the Brand product. Pharmacokinetic studies are conducted whereby each of the preparations are administered in a cross-over study to volunteer subjects, generally healthy individuals but occasionally in patients. Serum/Plasma samples are obtained at regular intervals and ...
... Generic product with that of the Brand product. Pharmacokinetic studies are conducted whereby each of the preparations are administered in a cross-over study to volunteer subjects, generally healthy individuals but occasionally in patients. Serum/Plasma samples are obtained at regular intervals and ...
Bodybuilding Supplement Update
... there’s a recent study showing that a single dose of ephedra-guarana supplement can produce significant increases in blood pressure and resting heart rate in healthy young adults. However, I believe this is a fake report. You see, the first and third authors of this paper have served as “expert witn ...
... there’s a recent study showing that a single dose of ephedra-guarana supplement can produce significant increases in blood pressure and resting heart rate in healthy young adults. However, I believe this is a fake report. You see, the first and third authors of this paper have served as “expert witn ...
GlucoNorm PM
... reproduction studies, measurable levels of repaglinide were detected in the breast milk of the dams and lowered blood glucose levels were observed in the pups. It is not known whether GlucoNorm® is excreted in human milk. GlucoNorm® is not recommended in nursing women because the potential for hypog ...
... reproduction studies, measurable levels of repaglinide were detected in the breast milk of the dams and lowered blood glucose levels were observed in the pups. It is not known whether GlucoNorm® is excreted in human milk. GlucoNorm® is not recommended in nursing women because the potential for hypog ...
Pharmacy update What`s new in the world of pharmaceuticals?
... • May occur at any time; more common early on – Recommendations for patients • STOP medication and contact prescriber at first signs of • Skin pain, reddening, or blisters + systemic symptoms such as fever or sore throat. ...
... • May occur at any time; more common early on – Recommendations for patients • STOP medication and contact prescriber at first signs of • Skin pain, reddening, or blisters + systemic symptoms such as fever or sore throat. ...
IN VIVO SATIVA Research Article
... The preliminary phytochemical screening of methanolic extracts of N. sativa from different germination phases showed the presence of alkaloids, flavonoids, terpenes, saponins, and tannins in our previous study which showed higher content of these metabolites during germination phases [9, 10]. Thus, ...
... The preliminary phytochemical screening of methanolic extracts of N. sativa from different germination phases showed the presence of alkaloids, flavonoids, terpenes, saponins, and tannins in our previous study which showed higher content of these metabolites during germination phases [9, 10]. Thus, ...
PCF Guidelines: Palliative sedation in the imminently dying
... Generally given only if it is intended to reduce a patient’s level of consciousness: • start with 25mg SC stat and q1h p.r.n. (12.5mg in the elderly) • if necessary, titrate dose according to response • maintain with 50–300mg/24h CSCI Although high-dose levomepromazine (≥100mg/24h) is generally best ...
... Generally given only if it is intended to reduce a patient’s level of consciousness: • start with 25mg SC stat and q1h p.r.n. (12.5mg in the elderly) • if necessary, titrate dose according to response • maintain with 50–300mg/24h CSCI Although high-dose levomepromazine (≥100mg/24h) is generally best ...
Pharmacokinetics
... Many CYP isozymes have been identified and cloned, and their role in metabolizing specific drugs elucidated. Each isozyme catalyzes a different but overlapping spectrum of oxidative reactions. Most drug biotransformation is catalyzed by three CYP families named CYP1, CYP2, and CYP3. The different CY ...
... Many CYP isozymes have been identified and cloned, and their role in metabolizing specific drugs elucidated. Each isozyme catalyzes a different but overlapping spectrum of oxidative reactions. Most drug biotransformation is catalyzed by three CYP families named CYP1, CYP2, and CYP3. The different CY ...
Potentially Harmful Drugs in the Elderly: Beers List
... In 1991, Dr. Mark Beers and colleagues published a methods paper describing the development of a consensus list of medicines considered to be inappropriate for long-term care facility residents.12 The American Geriatrics Society Beers Criteria or “Beers list” is now in its fifth permutation.1 It is ...
... In 1991, Dr. Mark Beers and colleagues published a methods paper describing the development of a consensus list of medicines considered to be inappropriate for long-term care facility residents.12 The American Geriatrics Society Beers Criteria or “Beers list” is now in its fifth permutation.1 It is ...
Alnylam`s ALN-VSP Abstract Published by American Society of
... people are diagnosed with secondary liver cancer each year. About RNA Interference (RNAi) RNAi (RNA interference) is a revolution in biology, representing a breakthrough in understanding how genes are turned on and off in cells, and a completely new approach to drug discovery and development. Its di ...
... people are diagnosed with secondary liver cancer each year. About RNA Interference (RNAi) RNAi (RNA interference) is a revolution in biology, representing a breakthrough in understanding how genes are turned on and off in cells, and a completely new approach to drug discovery and development. Its di ...
Targeting Optimal Nutrient Absorption with
... Cosmoperine is able to enhance natural abilities of the skin to absorb nutrients (Badmaev, V et al., 2001; Majeed, M et al., 2005). Although Cosmoperine is based on a pungent principle, it is non-irritant and it interacts with the skin quantitatively and qualitatively in a different way than a punge ...
... Cosmoperine is able to enhance natural abilities of the skin to absorb nutrients (Badmaev, V et al., 2001; Majeed, M et al., 2005). Although Cosmoperine is based on a pungent principle, it is non-irritant and it interacts with the skin quantitatively and qualitatively in a different way than a punge ...
Azithromycin 200 mg/5 ml powder for oral suspension 1.3.1.3
... irregular heart beat (arrhythmia), including fast heart beat (ventricular tachycardia) increased risk of QT prolongation (which causes irregular heart beat) and torsades de pointes (life-threatening fast heart beat) low blood pressure inflammation of the pancreas (pancreatitis) discolouration of the ...
... irregular heart beat (arrhythmia), including fast heart beat (ventricular tachycardia) increased risk of QT prolongation (which causes irregular heart beat) and torsades de pointes (life-threatening fast heart beat) low blood pressure inflammation of the pancreas (pancreatitis) discolouration of the ...
Allosteric Modulation: a Novel Approach to Drug Discovery
... modulators enhance (positively modulate) the natural physiological activity of the receptor. Consequently, allosteric modulators can exert their effects while preserving normal physiological signaling patterns. By applying a non-competitive approach that preserves the physiological nature of endogen ...
... modulators enhance (positively modulate) the natural physiological activity of the receptor. Consequently, allosteric modulators can exert their effects while preserving normal physiological signaling patterns. By applying a non-competitive approach that preserves the physiological nature of endogen ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.