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Unit 3 Biochemistry
Unit 3 Biochemistry

... The stages of mitosis are shown out of order below. Label them with the correct name and put a number next to each to show the correct order, beginning with prophase. ...
14 Stem Cell Differentiation
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Intro to Genetics
Intro to Genetics

... 15. Each offspring cell produced by binary fission (mitosis) contains a. half the chromosomes of the original cell. b. twice as many chromosomes as the original cell had. c. an identical copy of the original cell’s chromosome. d. an independent assortment of the original cell’s chromosomes. 16. Cros ...
Worksheet on Cell Reproduction
Worksheet on Cell Reproduction

... In a new daughter cell produced from cell division, how do the numbers of mitochondria and other organelles compare with that of the parent cell? ________________________________________________________________________ ...
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... About 10 to 30% of offspring contain injected foreign DNA. Foreign DNA is present in equal amounts in all tissues ...
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Lesson Plans Teacher: Robinson Dates: 12:5

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Answer Key Biology 1 Exam 3 Spring 2016

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Epigenetics in stem-cell differentiation

Embryonic stem cells are capable of self-renewing and differentiating to the desired fate depending on its position within the body. Stem cell homeostasis is maintained through epigenetic mechanisms that are highly dynamic in regulating the chromatin structure as well as specific gene transcription programs. Epigenetics has been used to refer to changes in gene expression, which are heritable through modifications not affecting the DNA sequence.The mammalian epigenome undergoes global remodeling during early stem cell development that requires commitment of cells to be restricted to the desired lineage. There has been multiple evidence suggesting that the maintenance of the lineage commitment of stem cells are controlled by epigenetic mechanisms such as DNA methylation, histone modifications and regulation of ATP-dependent remolding of chromatin structure. Based on the histone code hypothesis, distinct covalent histone modifications can lead to functionally distinct chromatin structures that influence the fate of the cell.This regulation of chromatin through epigenetic modifications is a molecular mechanism that will determine whether the cell will continue to differentiate into the desired fate. A research study performed by Lee et al. examined the effects of epigenetic modifications on the chromatin structure and the modulation of these epigenetic markers during stem cell differentiation through in vitro differentiation of murine embryonic stem (ES) cells.
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