Case Study #1 Use of bioinformatics in drug development
... •To understand ‘what forces’ are responsible for ligands binding to Receptors/Enzymes, •The observed structure of Protein is generally a consequence of the hydrophobic effect! •Proteins generally bury hydrophobic residues inside the core,while exposing hydrophilic residues to the exterior Salt-brid ...
... •To understand ‘what forces’ are responsible for ligands binding to Receptors/Enzymes, •The observed structure of Protein is generally a consequence of the hydrophobic effect! •Proteins generally bury hydrophobic residues inside the core,while exposing hydrophilic residues to the exterior Salt-brid ...
The Never-Ending Story—The Origin and Diversification of Life
... ribosomal complex, likely utilizing an early version of the genetic code. The near, and not absolute, universality of the genetic code is also proof of its potential malleability and lends credence to a time when a common language was still being worked out. Regardless, it’s becoming a lot clearer t ...
... ribosomal complex, likely utilizing an early version of the genetic code. The near, and not absolute, universality of the genetic code is also proof of its potential malleability and lends credence to a time when a common language was still being worked out. Regardless, it’s becoming a lot clearer t ...
Atoms, Elements and Compounds Home
... are several different types of nitrogen oxide. When this happens, the number of the type of atom that can be different is shown by using a prefix: ‘mono-’ (one), ‘di-’ (two) or ‘tri-’ (three). For example, the compound with the formula NO is called nitrogen monoxide and NO2 is nitrogen dioxide. If t ...
... are several different types of nitrogen oxide. When this happens, the number of the type of atom that can be different is shown by using a prefix: ‘mono-’ (one), ‘di-’ (two) or ‘tri-’ (three). For example, the compound with the formula NO is called nitrogen monoxide and NO2 is nitrogen dioxide. If t ...
PPT - gserianne.com
... • lower activation energy needed to start reactions • globular proteins with specific shapes • not consumed in chemical reactions • substrate specific • shape of active site determines which substrate(s) the enzyme can act on Figure From: Marieb & Hoehn, Human Anatomy & Physiology, 9th ed., Pearson ...
... • lower activation energy needed to start reactions • globular proteins with specific shapes • not consumed in chemical reactions • substrate specific • shape of active site determines which substrate(s) the enzyme can act on Figure From: Marieb & Hoehn, Human Anatomy & Physiology, 9th ed., Pearson ...
function
... However, the active sites are found to be strikingly similar. Figure4-45. Comparison of the active sites of L-aspartate aminotransferase (left) and D-amino acid aminotransferase (right) ...
... However, the active sites are found to be strikingly similar. Figure4-45. Comparison of the active sites of L-aspartate aminotransferase (left) and D-amino acid aminotransferase (right) ...
The Chemistry of Life
... • Mixture of water and undissolved material • Movement of water keeps undissolved materials suspended so they don’t settle out • When movement of water stops, materials will settle to the bottom • Blood in your body contains solutions and suspensions: • The liquid part of your blood is mostly water ...
... • Mixture of water and undissolved material • Movement of water keeps undissolved materials suspended so they don’t settle out • When movement of water stops, materials will settle to the bottom • Blood in your body contains solutions and suspensions: • The liquid part of your blood is mostly water ...
File - Mr Weng`s IB Chemistry
... Inductively Coupled Plasma (ICP) Spectroscopy using Mass Spectroscopy ICP-MS and Optical Emission Spectroscopy ICP-OES. • Deduction of redox equations for the reduction of metals. • Relating the method of extraction to the position of a metal on the activity series. • Explanation of the production o ...
... Inductively Coupled Plasma (ICP) Spectroscopy using Mass Spectroscopy ICP-MS and Optical Emission Spectroscopy ICP-OES. • Deduction of redox equations for the reduction of metals. • Relating the method of extraction to the position of a metal on the activity series. • Explanation of the production o ...
MODULE 2
... 76. Each end of the DNA double helix contains a 5’ end at one strand and the 3’ end on the other strand. This describes what characteristic of the DNA structure? A. Base pairing B. Complementary C. Antiparallel D. Semiconservative replication ...
... 76. Each end of the DNA double helix contains a 5’ end at one strand and the 3’ end on the other strand. This describes what characteristic of the DNA structure? A. Base pairing B. Complementary C. Antiparallel D. Semiconservative replication ...
Proteomics and Mass Spectroscopy
... – about 1,000,000 proteins. • The human body may contain more than 2 million proteins, each having different functions. • The discrepancy implies that protein diversity cannot be fully characterized by gene expression analysis, thus proteomics is useful for characterizing cells and tissues. ...
... – about 1,000,000 proteins. • The human body may contain more than 2 million proteins, each having different functions. • The discrepancy implies that protein diversity cannot be fully characterized by gene expression analysis, thus proteomics is useful for characterizing cells and tissues. ...
Patrick Cramer Anton Meinhart, Tobias Silberzahn and
... The influence of divalent metal ions on Ssu72 activity was also examined (Fig. 2A). The addition of 1 mM Mg2⫹, Mn2⫹, or Ca2⫹ had essentially no effect, but at 10 mM concentrations, product formation was reduced to 60, 45, and 80%, respectively. In contrast, 1 mM Co2⫹, Ni2⫹, or Cu2⫹ were sufficient t ...
... The influence of divalent metal ions on Ssu72 activity was also examined (Fig. 2A). The addition of 1 mM Mg2⫹, Mn2⫹, or Ca2⫹ had essentially no effect, but at 10 mM concentrations, product formation was reduced to 60, 45, and 80%, respectively. In contrast, 1 mM Co2⫹, Ni2⫹, or Cu2⫹ were sufficient t ...
Chemistry II Exams and Answer Keys 2015 Season
... 16. Oxygen (O2) and Ozone (O3) are allotropes of the element oxygen. Which of the following pairs is NOT an allotropic pair? A. Cgraphite and Cdiamond B. rhombic sulfur and amorphous sulfur C. white tin and gray tin D. nitrogen-14 and nitrogen-15 17. Green light breaks the bond between two chlorine ...
... 16. Oxygen (O2) and Ozone (O3) are allotropes of the element oxygen. Which of the following pairs is NOT an allotropic pair? A. Cgraphite and Cdiamond B. rhombic sulfur and amorphous sulfur C. white tin and gray tin D. nitrogen-14 and nitrogen-15 17. Green light breaks the bond between two chlorine ...
SI Worksheet #10 (Chapter 9) BY 123 Meeting 10/8/2015 Chapter 9
... 22. Electrons are transferred from NADH to the first molecule in the electron transport chain in complex I. 23. What are cytochromes? Prosthetic groups (heme group), that accept and donate electrons 24. FADH2 adds electrons to complex II first. 25. What is chemiosmosis? The movement of ions across ...
... 22. Electrons are transferred from NADH to the first molecule in the electron transport chain in complex I. 23. What are cytochromes? Prosthetic groups (heme group), that accept and donate electrons 24. FADH2 adds electrons to complex II first. 25. What is chemiosmosis? The movement of ions across ...
Lesson6.5_Translation Process
... How does translation occur? 1. The ribosome attaches to the mRNA molecule. 2. The tRNA attaches to the mRNA. The tRNA anticodon attaches to the mRNA codon. 3. The first two amino acids are joined/connected and the first tRNA leaves, and the ribosome moves along the mRNA to the next codon ...
... How does translation occur? 1. The ribosome attaches to the mRNA molecule. 2. The tRNA attaches to the mRNA. The tRNA anticodon attaches to the mRNA codon. 3. The first two amino acids are joined/connected and the first tRNA leaves, and the ribosome moves along the mRNA to the next codon ...
One 2-fold axis of symmetry
... through 180˚ gives an indistinguishable structure. Thus, there is a 2-fold axis of symmetry, also called a dyad. In haemoglobin we are concerned with a tetramer. (Although there are two different subunits, and , we regard them as practically identical and qualify our statements by referring to ps ...
... through 180˚ gives an indistinguishable structure. Thus, there is a 2-fold axis of symmetry, also called a dyad. In haemoglobin we are concerned with a tetramer. (Although there are two different subunits, and , we regard them as practically identical and qualify our statements by referring to ps ...
Practice Test Packet
... 1) Pentaamminechlorochromium(III)chloride ________________________ 2) Bariumtetrabromoferrate(III) __________________________ 3) Hexaaquachromium(III) sulfate ________________________ 27. How many unpaired electrons are present in the tetrahedral ion FeCl4-? Draw the crystal field diagram. 28. Draw ...
... 1) Pentaamminechlorochromium(III)chloride ________________________ 2) Bariumtetrabromoferrate(III) __________________________ 3) Hexaaquachromium(III) sulfate ________________________ 27. How many unpaired electrons are present in the tetrahedral ion FeCl4-? Draw the crystal field diagram. 28. Draw ...
Atoms and Molecules
... type of ions involved not how many of each ion cations: name the element; if more than one oxidation state is possible (d-block) follow with the charge in Roman numerals in parentheses anions: if monatomic then use the elemental name but with an –ide ending if polyatomic then use the memorized name ...
... type of ions involved not how many of each ion cations: name the element; if more than one oxidation state is possible (d-block) follow with the charge in Roman numerals in parentheses anions: if monatomic then use the elemental name but with an –ide ending if polyatomic then use the memorized name ...
Chapter 1 Macromolecular Structure and Dynamics
... L-: rotate in an anti-clockwise direction around the chrial carbon. D-: rotate in a clockwise direction around the chrial carbon. Biopolymers are typically constructed from only one enantimer (L form) of the monomer building block. Amino acid / the chiral center is the carbon directly adjacent to th ...
... L-: rotate in an anti-clockwise direction around the chrial carbon. D-: rotate in a clockwise direction around the chrial carbon. Biopolymers are typically constructed from only one enantimer (L form) of the monomer building block. Amino acid / the chiral center is the carbon directly adjacent to th ...
Unit 3 Revision Notes 213.00KB 2017-03-01 18
... Br2 + 2NaI = I2 + 2KBr THE TRANSITION METALS This is the block which appears in the middle of the periodic table. It contains many of the metals in everyday use, such as iron, nickel and copper. Properties These metals tend to be strong and dense, with a fairly high melting point. Their reactions ar ...
... Br2 + 2NaI = I2 + 2KBr THE TRANSITION METALS This is the block which appears in the middle of the periodic table. It contains many of the metals in everyday use, such as iron, nickel and copper. Properties These metals tend to be strong and dense, with a fairly high melting point. Their reactions ar ...
CO ORDINATION COMPOUNDS
... In the diamagnetic octahedral complex,[Co(NH3)6]3+ , the cobalt ion is in +3 oxidation state and has the electronic configuration 3d6. The hybridisation scheme is as shown in diagram. ...
... In the diamagnetic octahedral complex,[Co(NH3)6]3+ , the cobalt ion is in +3 oxidation state and has the electronic configuration 3d6. The hybridisation scheme is as shown in diagram. ...
PROTEIN METABOLISM
... but many liver enzymes turn over in a couple of days. Some regulatory enzymes have half-lives measured in hours or minutes. The majority of the amino acids released during protein degradation are promptly reincorporated into fresh proteins. ...
... but many liver enzymes turn over in a couple of days. Some regulatory enzymes have half-lives measured in hours or minutes. The majority of the amino acids released during protein degradation are promptly reincorporated into fresh proteins. ...
ENZYMES - York Catholic District School Board
... of various chemical substances in manufacturing, or for laboratory tests because they are such efficient ways to speed up chemical reactions Enzymes can be used over and over again to catalyze numerous reactions (they will ...
... of various chemical substances in manufacturing, or for laboratory tests because they are such efficient ways to speed up chemical reactions Enzymes can be used over and over again to catalyze numerous reactions (they will ...
Cellular respiration photosynthesis
... Which of the following organisms use alcoholic fermentation to allow glycolysis to continue to produce ATP? ...
... Which of the following organisms use alcoholic fermentation to allow glycolysis to continue to produce ATP? ...
Metalloprotein
Metalloprotein is a generic term for a protein that contains a metal ion cofactor. A large number of all proteins are part of this category.