Question paper - Unit F335/01 - Chemistry by design
... (d) Dorzolamide is more soluble in water than compound A. One reason is because it can form hydrogen bonds with water using the amine group that is not present in compound A. Show the formation of one of these hydrogen bonds on the structure of dorzolamide above. Indicate relevant lone pairs and par ...
... (d) Dorzolamide is more soluble in water than compound A. One reason is because it can form hydrogen bonds with water using the amine group that is not present in compound A. Show the formation of one of these hydrogen bonds on the structure of dorzolamide above. Indicate relevant lone pairs and par ...
1 Pyruvate and acetate metabolism (The citric acid cycle) I. Pyruvate
... 1. AcetylCoA ----> isocitrate - see text in V&V p. 550 for mechanism At this stage, one C-C bond remains to be broken, but ironically, now the compound is too small to have handles for enzymes to work with and the chemistry involved would be quite difficult. Therefore a new C-C bond must be formed t ...
... 1. AcetylCoA ----> isocitrate - see text in V&V p. 550 for mechanism At this stage, one C-C bond remains to be broken, but ironically, now the compound is too small to have handles for enzymes to work with and the chemistry involved would be quite difficult. Therefore a new C-C bond must be formed t ...
Workshop3Cellsans
... the addition of an inorganic phosphate to a molecule of ADP. Both reactions are catalyzed by enzymes that couple the formation of ATP to an exergonic reaction that provides the energy for the synthesis of ATP. Substrate-level phosphorylation occurs when enzymes involved in glycolysis, the Krebs cycl ...
... the addition of an inorganic phosphate to a molecule of ADP. Both reactions are catalyzed by enzymes that couple the formation of ATP to an exergonic reaction that provides the energy for the synthesis of ATP. Substrate-level phosphorylation occurs when enzymes involved in glycolysis, the Krebs cycl ...
Many people today are hooked on “fat free” or
... the addition of an inorganic phosphate to a molecule of ADP. Both reactions are catalyzed by enzymes that couple the formation of ATP to an exergonic reaction that provides the energy for the synthesis of ATP. Substrate-level phosphorylation occurs when enzymes involved in glycolysis, the Krebs cycl ...
... the addition of an inorganic phosphate to a molecule of ADP. Both reactions are catalyzed by enzymes that couple the formation of ATP to an exergonic reaction that provides the energy for the synthesis of ATP. Substrate-level phosphorylation occurs when enzymes involved in glycolysis, the Krebs cycl ...
Fragmentation of doubly charged metal–acetamide complexes
... (reaction (2)), giving [Ca(L − H)]+ (m/z = 98) and protonated acetamide (m/z = 60) closely competes with acetamide elimination (reaction (3)), giving [Ca(L)]2+ (m/z = 49.5) (Fig. 1a). As the collision energy increased, the products of amide-bond cleavage (reaction (4)), [Ca(NH2 )]+ (m/z = 56) and [C ...
... (reaction (2)), giving [Ca(L − H)]+ (m/z = 98) and protonated acetamide (m/z = 60) closely competes with acetamide elimination (reaction (3)), giving [Ca(L)]2+ (m/z = 49.5) (Fig. 1a). As the collision energy increased, the products of amide-bond cleavage (reaction (4)), [Ca(NH2 )]+ (m/z = 56) and [C ...
Cleaning Up With Atom Economy
... economy introduce a new goal into reaction chemistry: designing reactions so that the atoms present in the starting materials end up in the product rather than in the wastestream. This concept provides a framework for evaluating different chemistries, and an ideal to strive for in new reaction chemi ...
... economy introduce a new goal into reaction chemistry: designing reactions so that the atoms present in the starting materials end up in the product rather than in the wastestream. This concept provides a framework for evaluating different chemistries, and an ideal to strive for in new reaction chemi ...
Structural Biochemistry/Enzyme/Active Site
... inactivation rate or kinact. Binding of irreversible inhibitors can be prevented by competition with either substrate or a second, reversible inhibitor since formation of EI may compete with ES. In addition, some reversible inhibitors can form irreversible products by binding so tightly to their tar ...
... inactivation rate or kinact. Binding of irreversible inhibitors can be prevented by competition with either substrate or a second, reversible inhibitor since formation of EI may compete with ES. In addition, some reversible inhibitors can form irreversible products by binding so tightly to their tar ...
Protein-RNA interactions: Structural analysis and functional classes
... structures have been solved. However, the publication of the structure of the 50S and 30S ribosome subunits in 2000,1,2 and the advent of the structural genomics projects means that structural information for more than 350 protein–RNA complexes is currently available. This increased volume of data m ...
... structures have been solved. However, the publication of the structure of the 50S and 30S ribosome subunits in 2000,1,2 and the advent of the structural genomics projects means that structural information for more than 350 protein–RNA complexes is currently available. This increased volume of data m ...
MANE6960 Homework05 Wyatt.pdf
... Staged combustion – Typically a rich-lean staging of combustion is used. The NOx reductions range from 10 to 40 %. Temperature reduction – Reducing the amount of air preheat and/or injecting water into the flame reduce the combustion temperature, and, consequently NOx formation. Similarly, water inj ...
... Staged combustion – Typically a rich-lean staging of combustion is used. The NOx reductions range from 10 to 40 %. Temperature reduction – Reducing the amount of air preheat and/or injecting water into the flame reduce the combustion temperature, and, consequently NOx formation. Similarly, water inj ...
Biochem Chapter 44 [4-20
... The ATP is used for ion transport across the cell membrane, phosphorylation of membrane proteins, and priming rxns of glycolysis RBC glycolysis uses the Rapoport-Luebering shunt to generate 2,3-bisphosphoglycerate (2,3BPG) o RBCs have way more 2,3-BPG than other cells o 2,3-BPG is needed for the pho ...
... The ATP is used for ion transport across the cell membrane, phosphorylation of membrane proteins, and priming rxns of glycolysis RBC glycolysis uses the Rapoport-Luebering shunt to generate 2,3-bisphosphoglycerate (2,3BPG) o RBCs have way more 2,3-BPG than other cells o 2,3-BPG is needed for the pho ...
Methods to detect and characterize metal ion binding sites in
... Nevertheless, a profound characterization of this crucial interaction is the basis to understand folding, structure and function of any RNA, especially catalytically active ribozymes. Three major problems are to be overcome in every method that aims at investigating this relationship: (i) Only few m ...
... Nevertheless, a profound characterization of this crucial interaction is the basis to understand folding, structure and function of any RNA, especially catalytically active ribozymes. Three major problems are to be overcome in every method that aims at investigating this relationship: (i) Only few m ...
CH 151 Companion
... to this method other than it provides a logical way to deduce order and causality for natural phenomena. An inherent part of the scientific method is the element of creativity. This is what makes possible the development of completely new concepts. This experiment is designed to allow you to use som ...
... to this method other than it provides a logical way to deduce order and causality for natural phenomena. An inherent part of the scientific method is the element of creativity. This is what makes possible the development of completely new concepts. This experiment is designed to allow you to use som ...
1 • Introduction The Scientific Method (1 of 20) 1
... • metals often are written with the ° symbol to emphasize that the metal is in the neutral elemental state, not an ion. • some compounds have common names that you should just know... water, H 2 O; ammonia, NH3 ; methane, CH4 • remember the seven diatomic elements so they can be written as diatomic ...
... • metals often are written with the ° symbol to emphasize that the metal is in the neutral elemental state, not an ion. • some compounds have common names that you should just know... water, H 2 O; ammonia, NH3 ; methane, CH4 • remember the seven diatomic elements so they can be written as diatomic ...
(B) Where CO 2
... formed is from oxidative phosphorylation, ATP yield in respiration needs a supply of O2. Since O2 “pulls” electrons down the ETC then if there is not enough Oxygen the ETC will stop (and stop ATP formation). FERMENTATION - is a process that some cells can use to oxidize food and make ATP without the ...
... formed is from oxidative phosphorylation, ATP yield in respiration needs a supply of O2. Since O2 “pulls” electrons down the ETC then if there is not enough Oxygen the ETC will stop (and stop ATP formation). FERMENTATION - is a process that some cells can use to oxidize food and make ATP without the ...
Nov_16
... Pyruvate carboxylase o Part of the filling up reaction o Citric synthase…part of TCA cycle o Allosterically regulated by acetyl-CoA o When Pyruvate carboxylase is activated, Oxaloacetate up, more citrate can be formed, therefore reducing acetyl-COA and boosting TCA cycle This is called a “filling ...
... Pyruvate carboxylase o Part of the filling up reaction o Citric synthase…part of TCA cycle o Allosterically regulated by acetyl-CoA o When Pyruvate carboxylase is activated, Oxaloacetate up, more citrate can be formed, therefore reducing acetyl-COA and boosting TCA cycle This is called a “filling ...
Supplemental Information
... ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The encoded protein also collaborates with a network of proteins to contro ...
... ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The encoded protein also collaborates with a network of proteins to contro ...
Biomolecular chemistry 3. Translating the genetic code
... In bacteria there is a specific tRNA, known as the initiator tRNA, that carries fMet. This fMet-tRNA recognizes the first codon AUG following a purine-rich sequence, known as the Shine-Delgarno sequence (or box), that base-pairs with a complementary sequence in the ribosome. This is essentially the ...
... In bacteria there is a specific tRNA, known as the initiator tRNA, that carries fMet. This fMet-tRNA recognizes the first codon AUG following a purine-rich sequence, known as the Shine-Delgarno sequence (or box), that base-pairs with a complementary sequence in the ribosome. This is essentially the ...
Topic guide 1.2: Enzymes
... more quickly. However, applying too much heat can cause enzymes to denature. The increased vibrations and collisions put strains on the bonds of the tertiary structure and can break the hydrogen and ionic bonds. The breaking of these bonds affects the important three-dimensional shape; more importan ...
... more quickly. However, applying too much heat can cause enzymes to denature. The increased vibrations and collisions put strains on the bonds of the tertiary structure and can break the hydrogen and ionic bonds. The breaking of these bonds affects the important three-dimensional shape; more importan ...
7. Lipidic metabolism in parasitic platyhelminthes
... The energetic metabolism and the presence or absence of fatty acid (FA) catabolism in cestodes remains unclear. Although larvae and adult forms of cestodes are likely to have at least some oxygen supply, in many species the oxygen tension in the central region may be zero. In addition to living in e ...
... The energetic metabolism and the presence or absence of fatty acid (FA) catabolism in cestodes remains unclear. Although larvae and adult forms of cestodes are likely to have at least some oxygen supply, in many species the oxygen tension in the central region may be zero. In addition to living in e ...
Metalloprotein
Metalloprotein is a generic term for a protein that contains a metal ion cofactor. A large number of all proteins are part of this category.