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5` Flanking Sequences of the Rat Tyrosine Hydroxylase Gene Target
5` Flanking Sequences of the Rat Tyrosine Hydroxylase Gene Target

RNA-Seq analysis
RNA-Seq analysis

The pattern
The pattern

... But: ...
PDF - Journal of Cancer Metastasis and Treatment
PDF - Journal of Cancer Metastasis and Treatment

... take into account risk factors such as age at menarche, menopausal status, and environmental factors. It is important to investigate the interaction between single-nucleotide polymorphisms and these factors on the risk of breast cancer in a larger sample size in further studies. Based on our study, ...
AtCSLD3, A Cellulose Synthase-Like Gene
AtCSLD3, A Cellulose Synthase-Like Gene

... Confocal microscopy was done on primary roots stained with propidium iodide (PI) to visualize the cell’s periphery. The meristematic and elongation zone of the mutant primary root was indistinguishable from wild type. In the differentiation zone where root hairs initiate, elongate, and maturate alon ...
KEY Heredity Study Guide
KEY Heredity Study Guide

... 2. Know the steps for Hands-Only CPR 3. Identify the structure, function, and location of the DNA molecule. Know how the base pairs go together. 4. Explain the difference between phenotype and genotype. 5. Distinguish between heterozygous/hybrid and homozygous/pure. 6. Describe the relationship betw ...
reproduction
reproduction

... widely studied epigenetic process associated with genomic imprinting, although whether it represents the primary ‘imprint’ distinguishing the parental alleles is currently under debate. Differential methylation arises in specific gene regions known as differentially methylated regions or DMRs. Two t ...
Animal Breeding/Genetics For
Animal Breeding/Genetics For

... the probability that a particular phenotype survives and reproduces. – Not all phenotypes are equally Fit to compete in a particular environment. – Fitness is the capability of a phenotype and the corresponding genotype to survive and reproduce in a given environment. ...
Section 4
Section 4

... A cell containing both sets of chromosomes is Diploid and is represented by the symbol 2N. Most body cells are diploid. A cell containing only one set of chromosomes is Haploid and is represented by the symbol N. Gametes (sperm & egg) are haploid. ...
Mendelian Traits
Mendelian Traits

... about the biological nature of the gene. There are many ways in which the DNA blueprint for the PAH enzyme can go awry and if any one of them happens, then the translated product of that DNA will not work correctly. As a result, over 500 different alleles at the PAH locus can cause the disorder (Scri ...
Identification of the tRNA-binding Protein Arc1p as a Novel Target of
Identification of the tRNA-binding Protein Arc1p as a Novel Target of

... Yeast Strains, Vectors, and Media—The S. cerevisiae strains used in this study are listed in Table I. For recombinant plasmid constructions, the S. cerevisiae/E. coli shuttle vectors YCplac33 (14), p414MET25 (15), pVT-100U (16), pTRC-HISA (Invitrogen) and the E. coli plasmid pQE70 (Qiagen) served as ...
Database of cattle candidate genes and genetic markers for
Database of cattle candidate genes and genetic markers for

... well as development and function of endocrine system. Eight loci are involved in cell mediated immune response and structure and development of lymphoid tissue and the other eight are involved in cellular development, movement and cancer. Three loci were associated with organ morphology, development ...
DNA and the Book of Mormon: A Phylogenetic Perspective
DNA and the Book of Mormon: A Phylogenetic Perspective

... ability to obtain external funding from a nationally peer-reviewed granting agency and to publish the results in a reputable scientific journal. To be funded at the national level means that a research proposal has undergone the highest degree of scrutiny and been approved by those best able to judg ...
Th17/Treg ratio derived using DNA methylation asthmatic response
Th17/Treg ratio derived using DNA methylation asthmatic response

... Background: The imbalance between Th17 and Treg cells has been studied in various diseases including allergic asthma but their roles have not been fully understood in the development of the late phase asthmatic response. Objectives: To determine changes in Th17 and Treg cell numbers between isolated ...
Document
Document

Sexual stages in trypanosomes and implications
Sexual stages in trypanosomes and implications

... pletely new parental pair of trypanosomes was used while in the other crosses at least one of the « original » parental clones (STIB 247 or STIB 386) was used. In addition, using T. brucei clone STIB 247 and another clone from East Africa (STIB 777) for simultaneous transmission, 4 new hybrid clones ...
Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1a/tcf1
Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1a/tcf1

... 2000; Sun and Hopkins, 2001). In teleosts, only one hnf1 form was reported in Atlantic salmon (Deryckere et al., 1995) and two hnf1 partial cDNAs in tilapia were identified by us (Huang et al., 2001). In zebrafish, conserved vhnf1/hnf1b, which is involved in kidney cysts formation similar to human s ...
The Drosophila Gene Disruption Project: Progress
The Drosophila Gene Disruption Project: Progress

... ABSTRACT The Drosophila Gene Disruption Project (GDP) has created a public collection of mutant strains containing single transposon insertions associated with different genes. These strains often disrupt gene function directly, allow production of new alleles, and have many other applications for a ...
Coding Regions of MSX1 do not Contribute to Non
Coding Regions of MSX1 do not Contribute to Non

BIL 250 – Genetics Krempels – Summer 2015 Study Guide for Exam I
BIL 250 – Genetics Krempels – Summer 2015 Study Guide for Exam I

... Understand the meaning/significance of: polygenic inheritance as it relates to continuous traits Know the basic mode of inheritance for mitochondrial and chloroplast genes. Understand the phenomenon of maternal (mitochondrial) inheritance, and the genetic drift that causes Cytoplasmic Segregation an ...
embj201490542-sup-0013
embj201490542-sup-0013

... target genes. To define genes that become induced upon Scl expression, SclhCD4 reporter ES cells (Chung et al, 2002) were used to identify genes that become up-regulated in day 4 Scl-expressing mesoderm (Flk1+Scl+) as compared to Flk1+Scl- mesodermal precursors that give rise to other mesodermal lin ...
Fig. 10-5, p. 158
Fig. 10-5, p. 158

... the maternal or paternal member of a homologous pair can end up at either pole. This can also lead to different traits in each new generation. ...
Gene Section JAG1 (jagged 1 (Alagille syndrome)) Atlas of Genetics and Cytogenetics
Gene Section JAG1 (jagged 1 (Alagille syndrome)) Atlas of Genetics and Cytogenetics

... Table 2. EGF-like repeats of the human JAG1 protein. A : the 16 EGF motifs are aligned. A 24-amino acid insertion is present in EGF10 (in grey, as in human JAG2 protein). The numbers above the sequences refer to cysteine residues (C in blue). Each EGF-like repeat contains 6 cysteine residues, able t ...
The amphioxus hairy family: differential fate after duplication.
The amphioxus hairy family: differential fate after duplication.

... Several representatives of the hairy family have been so far isolated from a range of protostome and vertebrate species. In protostomes such as Drosophila they have been implicated in segmentation, peripheral nervous system development, and in somatic sex determination. In Tribolium, only a role dur ...
Scale-free networks - Chair of Computational Biology
Scale-free networks - Chair of Computational Biology

... added vertices to already well connected ones.  Fell and Wagner (2000) argued that vertices with many connections in metabolic network were metabolites originating very early in the course of evolution where they shaped a core metabolism.  Analogously, highly connected domains could have also orig ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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