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Scale-free networks - Chair of Computational Biology
Scale-free networks - Chair of Computational Biology

... added vertices to already well connected ones.  Fell and Wagner (2000) argued that vertices with many connections in metabolic network were metabolites originating very early in the course of evolution where they shaped a core metabolism.  Analogously, highly connected domains could have also orig ...
The amphioxus hairy family: differential fate after duplication.
The amphioxus hairy family: differential fate after duplication.

... Several representatives of the hairy family have been so far isolated from a range of protostome and vertebrate species. In protostomes such as Drosophila they have been implicated in segmentation, peripheral nervous system development, and in somatic sex determination. In Tribolium, only a role dur ...
Molecular genetics of autosomal dominant retinitis pigmentosa
Molecular genetics of autosomal dominant retinitis pigmentosa

... some of the genes analysed (RP1, IMPDH1, NRL, and FSCN2) that caused amino acid substitutions (table 2). In particular, the RP1 gene has a significantly high frequency of missense variations with no pathogenic significance. Interestingly, one of these sequence variants, 5448CRA, which determines a p ...
Understanding Patterns of Inheritance Through Pedigree
Understanding Patterns of Inheritance Through Pedigree

... dominant. N represents a normal allele or version of the pigmentation gene. Albinism is the abnormal phenotype and is recessive. If the pigmentation gene is abnormal, it is represented by n. The genotype for albinism is represented as nn. If you cannot determine if an individual with normal pigmenta ...
Binding of a Growth Hormone- Inducible Nuclear Factor Is Mediated
Binding of a Growth Hormone- Inducible Nuclear Factor Is Mediated

... quantities of phosphotyrosine antibody (anti-pY) before the addition of Spi 2.1 GHRE probe and electrophoresis. Hx, Extract from hypophysectomized rats. B, Effects of PTPase on binding and inhibition of this effect by vanadate. Using hepatic nuclear extracts from GH-treated rats, reaction mixtures h ...
Phe
Phe

...  Phe concentrations consistently above normal, but not high to cause impaired cognitive development  does not need to be treated by diet ...
Meiosis
Meiosis

... • B. Two separate divisions – Meiosis I reduction division – Meiosis II “mitotic-like” division ...
Package `AnnotationBustR`
Package `AnnotationBustR`

... extractable. These will return in the accession table as "type not fully Ann". It is also possible that the sequence has no annotations at all, for which it will return "No Ann. For". If the function returns "Acc. Not Found", the accession number supplied could not be found on NCBI. If "Not On ACNUC ...
File S4 - G3: Genes | Genomes | Genetics
File S4 - G3: Genes | Genomes | Genetics

Ion AmpliSeq RNA Panels—quantitative targeted gene expression
Ion AmpliSeq RNA Panels—quantitative targeted gene expression

... (down to 500 pg). The new capabilities created with Ion AmpliSeq™ RNA primer design and optimized library preparation reagents allow researchers to specifically sequence genes from their own custom-designed pools or our fixed-panel content. This flexibility allows maximum utilization of sequencing d ...
Mark Scheme - Unit F215 - Control, genomes and
Mark Scheme - Unit F215 - Control, genomes and

... Answer DNA (combined) from (two) , sources / organisms ; ...
Joint Symposium of Waseda University and Peking University
Joint Symposium of Waseda University and Peking University

Lecture 5
Lecture 5

... Could this help explain how a female turkey could produce male progeny even when there are no male turkeys around to provide male gametes? ...
MID 4 Rachel J. Gordon, MD, MPH Introduction to Antimicrobials
MID 4 Rachel J. Gordon, MD, MPH Introduction to Antimicrobials

... ‘Resistant’ means that the organism will not be inhibited by acheivable drug concentrations in the blood. ‘Intermediate’ implies that if a high enough dose of the antibiotic is used, the antibiotic may be effective. The National Committee on Clinical Laboratory Standards (NCCLS) provides cutoff valu ...
Hthsci 2231
Hthsci 2231

... 13. In the gastrointestinal tract, cystic fibrosis causes difficulty in absorbing _________, _______, and ___________. 14. In the respiratory tract, what 3 functions are affected by the thick mucous secreted in patients with cystic fibrosis? 15. List 5 complications of cystic fibrosis that will even ...
Cell-cell communication during double fertilization
Cell-cell communication during double fertilization

345 - Timstar
345 - Timstar

... that alteration may not necessarily change the amino acid sequence of the subsequent protein produced due to degeneracy of the genetic code. On the other hand, SNPs that do not fall into a coding sequence may still affect that region of DNA in such a way by inducing gene splicing, transcription fact ...
Hidden Markov Model for protein secondary structure
Hidden Markov Model for protein secondary structure

... amino-acids classification; A,V,L,I,F,M,W,C=hydrophobic (h), S,T,Y,N,Q,H,P,D,E,K,R=polar (p), the motif hhpphh or pphhpp is found in 24% of the helices in our cross-validation set. Glycine (G) residues do not exhibit strong preference for either polar or apolar environment. It is thus considered as ...
An ATPase domain common to prokaryotic cell cycle proteins, sugar
An ATPase domain common to prokaryotic cell cycle proteins, sugar

Understanding conserved amino acids in proteins
Understanding conserved amino acids in proteins

... from the native structure of a protein. The summation is taken over all possible values of . Theoretical predictions from statistical-mechanical analysis can be compared with data on real proteins. In order to determine conservatism in real proteins we note that the space of sequences that fold int ...
Holbert, Daniel: Detecting motifs with EMOTIF-MAKER and MASIA: A critical comparison of two tools for finding protein motifs
Holbert, Daniel: Detecting motifs with EMOTIF-MAKER and MASIA: A critical comparison of two tools for finding protein motifs

... "wild-card " group that contains all of the residues, and groups for each individual amino acid. One can string EMOTIF-MAKER's substitution groups together in numerous ways to create motifs that match a given multiple alignment. The most intuitive motif, perhaps, is the one in which each position co ...
Quantitative Genetics
Quantitative Genetics

... Finding the gene(s) responsible is made much easier, but still a daunting task!! The gene may be one of many influencing the trait, other genes may lie in different regions! Works great in organisms like Drosophila, but human pedigrees are too small to work with! ...
View the BIO 105 Study Guide
View the BIO 105 Study Guide

... 2. Chemistry and how it relates to living things—atomic structure/bonding/pH/properties of water *define atom and energy *identify properties of atoms (protons, neutrons, and electrons) and the bonding of atoms to form compounds *identify and explain the different biochemical reactions (e.g. oxidati ...
CHOLESTEROL SYNTHESIS
CHOLESTEROL SYNTHESIS

... epoxide lanosterolcyclase to form the first steroidal intermediate LANOSTEROL. ...
Fatty acid - St John Brebeuf
Fatty acid - St John Brebeuf

... • Fats are constructed from two types of smaller molecules: glycerol and fatty acids • Glycerol is a three-carbon alcohol with a hydroxyl group attached to each carbon • A fatty acid consists of a carboxyl group attached to a long carbon skeleton ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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