Volume 18 - Number 9 September 2014 Atlas of Genetics and Cytogenetics
... Various cancers Note XB130 plays important roles in tumor progression by promoting cell proliferation, survival, motility and invasion in various cancer cells. Recently, XB130 has been identified in thyroid carcinoma (Shiozaki et al., 2011), esophageal squamous cell carcinoma (Shiozaki et al., 2013) ...
... Various cancers Note XB130 plays important roles in tumor progression by promoting cell proliferation, survival, motility and invasion in various cancer cells. Recently, XB130 has been identified in thyroid carcinoma (Shiozaki et al., 2011), esophageal squamous cell carcinoma (Shiozaki et al., 2013) ...
Glycogen Metabolism and Gluconeogenesis
... • Fructose-2,6-bisphosphate allosterically activates the glycolysis enzyme Phosphofructokinase-1, promoting the relaxed state, even at relatively high [ATP]. Activity in the presence of fructose2,6-bisphosphate is similar to that observed when [ATP] is low. Thus control by fructose-2,6-bisphosphate, ...
... • Fructose-2,6-bisphosphate allosterically activates the glycolysis enzyme Phosphofructokinase-1, promoting the relaxed state, even at relatively high [ATP]. Activity in the presence of fructose2,6-bisphosphate is similar to that observed when [ATP] is low. Thus control by fructose-2,6-bisphosphate, ...
Chapter 20 Notes
... • trans-addition of the elements of water across the double bond • Possible mechanisms are shown in Figure 20.18 • The actual mechanism is not known for certain ...
... • trans-addition of the elements of water across the double bond • Possible mechanisms are shown in Figure 20.18 • The actual mechanism is not known for certain ...
patrick_ch19_p1
... • G-Protein is split and subunit activates a membrane bound enzyme • Subunit binds to an allosteric binding site on enzyme • Induced fit results in opening of an active site • Intracellular reaction is catalysed Enzyme ...
... • G-Protein is split and subunit activates a membrane bound enzyme • Subunit binds to an allosteric binding site on enzyme • Induced fit results in opening of an active site • Intracellular reaction is catalysed Enzyme ...
The Family of SMF Metal Ion Transporters in Yeast Cells*
... Metal ions are vital for all organisms, and metal ion transporters play a crucial role in maintaining their homeostasis. The yeast (Saccharomyces cerevisiae) Smf transporters and their homologs in other organisms have a central role in the accumulation of metal ions and their distribution in differe ...
... Metal ions are vital for all organisms, and metal ion transporters play a crucial role in maintaining their homeostasis. The yeast (Saccharomyces cerevisiae) Smf transporters and their homologs in other organisms have a central role in the accumulation of metal ions and their distribution in differe ...
1 Biosynthesis and Chemical Properties of Natural Substances in
... thereby altering the rhizosphere (termed allelopathy; see Section 2.6) that leads to an inhibition of the growth of other, competing, plants. The process of compartmentation has three important implications: 1) The plant itself may not be in contact with the toxic compounds, because it is only after ...
... thereby altering the rhizosphere (termed allelopathy; see Section 2.6) that leads to an inhibition of the growth of other, competing, plants. The process of compartmentation has three important implications: 1) The plant itself may not be in contact with the toxic compounds, because it is only after ...
Proteome of amyloplasts isolated from
... and sulphur metabolism, nucleic acid-related reactions, synthesis of various building blocks, proteinrelated reactions, transport, signalling, stress, and a variety of other activities grouped under ‘miscellaneous’. The function of 12% of the proteins was unknown. The results highlight the role of t ...
... and sulphur metabolism, nucleic acid-related reactions, synthesis of various building blocks, proteinrelated reactions, transport, signalling, stress, and a variety of other activities grouped under ‘miscellaneous’. The function of 12% of the proteins was unknown. The results highlight the role of t ...
Dicot and monocot plants differ in retinoblastoma
... between the proteins encoded by these ZmRBR genes is ;90%. The predicted proteins display homology to the pocket A and B domains of the animal RBR protein family (Grafi et al., 1996; Xie et al., 1996; Ach et al., 1997). Recognition of the RB-binding LxCxE motif in plant D-type cyclins (Dahl et al., ...
... between the proteins encoded by these ZmRBR genes is ;90%. The predicted proteins display homology to the pocket A and B domains of the animal RBR protein family (Grafi et al., 1996; Xie et al., 1996; Ach et al., 1997). Recognition of the RB-binding LxCxE motif in plant D-type cyclins (Dahl et al., ...
A second enzyme protecting mineralocorticoid receptors from
... (20). 11-Dehydrocorticosterone (32) and 11b-hydroxy3a,5b-tetrahydroprogesterone are strong inhibitors of 11b-HSD2 (21). These agents all confer Na1 retention on glucocorticoids in adrenalectomized rat (20, 21). Although there is abundant evidence to support the hypothesis that 11b-HSD functions as a ...
... (20). 11-Dehydrocorticosterone (32) and 11b-hydroxy3a,5b-tetrahydroprogesterone are strong inhibitors of 11b-HSD2 (21). These agents all confer Na1 retention on glucocorticoids in adrenalectomized rat (20, 21). Although there is abundant evidence to support the hypothesis that 11b-HSD functions as a ...
Prediction for Essential Proteins with the Support Vector Machine
... There are 975 essential proteins and 3840 of Hwang et al. and Marcio et al., as shown in nonessential proteins in our dataset. The ratio of Table V. The best values of AUC, precision, recall, essential proteins to nonessential proteins is low, F-measure and MCC we get are 0.8502, 0.7872, nearly 1:4, ...
... There are 975 essential proteins and 3840 of Hwang et al. and Marcio et al., as shown in nonessential proteins in our dataset. The ratio of Table V. The best values of AUC, precision, recall, essential proteins to nonessential proteins is low, F-measure and MCC we get are 0.8502, 0.7872, nearly 1:4, ...
OsCUL3a Negatively Regulates Cell Death and
... adaptor BTB/POZ domain protein. These proteins together constitute a CRL3 complex (Hua and Vierstra, 2011). CUL3 is known to function in the regulation of PCD in animals. The deathassociated protein kinase (DAPK) enzyme is an apoptosis mediator involved in interferon-induced PCD in mammalian cells. ...
... adaptor BTB/POZ domain protein. These proteins together constitute a CRL3 complex (Hua and Vierstra, 2011). CUL3 is known to function in the regulation of PCD in animals. The deathassociated protein kinase (DAPK) enzyme is an apoptosis mediator involved in interferon-induced PCD in mammalian cells. ...
Muscles
... Rigor mortis is a recognizable sign of death (L. mors, mortis, f.) that is caused by a chemical change in the muscles, causing the limbs of the corpse to become stiff (L. rigor, oris, m.) and difficult to move or manipulate. Assuming mild temperatures, rigor usually sets in about 3-4 hours after cli ...
... Rigor mortis is a recognizable sign of death (L. mors, mortis, f.) that is caused by a chemical change in the muscles, causing the limbs of the corpse to become stiff (L. rigor, oris, m.) and difficult to move or manipulate. Assuming mild temperatures, rigor usually sets in about 3-4 hours after cli ...
Protein kinase CK2: a newcomer in the `druggable kinome`
... the most remarkable features of CK2, possibly representing the two sides of the same coin, are on one side constitutive activity and on the other extreme pleiotropy [5–7]. Unlike most protein kinases, which are turned on only in response to specific stimuli, the activity of CK2 catalytic subunits (α ...
... the most remarkable features of CK2, possibly representing the two sides of the same coin, are on one side constitutive activity and on the other extreme pleiotropy [5–7]. Unlike most protein kinases, which are turned on only in response to specific stimuli, the activity of CK2 catalytic subunits (α ...
biochemical tests and their use for identification purposes
... The pentose may be broken down further to acetate and pyruvate. Pyruvate produced from glycolysis may be converted to acetyl-CoA to begin respiration when exogenous electron acceptors such as oxygen, sulfate or nitrate are abundant. When exogenous electron acceptors are limited, fermentation pathway ...
... The pentose may be broken down further to acetate and pyruvate. Pyruvate produced from glycolysis may be converted to acetyl-CoA to begin respiration when exogenous electron acceptors such as oxygen, sulfate or nitrate are abundant. When exogenous electron acceptors are limited, fermentation pathway ...
Adipocyte metabolic pathways regulated by diet control
... (Spradling 1993). GSCs and their progeny grow and divide faster on yeast-rich relative to -poor diets, ...
... (Spradling 1993). GSCs and their progeny grow and divide faster on yeast-rich relative to -poor diets, ...
What is Xtend
... phosphatodyl-inositol-3-kinase pathway (PI3K). PI3K regulates glucose uptake through GLUT4 translocation and also increases amino acid uptake. Insulin, the body's "storage" hormone, works by activating the PI3K pathway. Interestingly, leucine ingestion causes insulin secretion, but leucine can also ...
... phosphatodyl-inositol-3-kinase pathway (PI3K). PI3K regulates glucose uptake through GLUT4 translocation and also increases amino acid uptake. Insulin, the body's "storage" hormone, works by activating the PI3K pathway. Interestingly, leucine ingestion causes insulin secretion, but leucine can also ...
Photosynthesis
... Calvin-Benson Cycle: -- PGA forms sugars and starches -- RuBP, NADP and ADP are regenerated ...
... Calvin-Benson Cycle: -- PGA forms sugars and starches -- RuBP, NADP and ADP are regenerated ...
Catabolic Plasmids - UQ eSpace
... cAMP-independent systems of Bacillus, acting in opposition to specific, plasmid-borne positive regulation. This is based generally on a two-component sensor/regulator ...
... cAMP-independent systems of Bacillus, acting in opposition to specific, plasmid-borne positive regulation. This is based generally on a two-component sensor/regulator ...
"Allosteric Activation of Kinases: Design and Application of RapR
... we call the “insertion loop.” This is in the β-sheet structured N-terminal lobe of the catalytic domain, a loop opposite the G-loop described in published studies as a critical structural element of all ePKs (Krupa et al., 2004). If a structure of the targeted catalytic domain is unavailable, one ca ...
... we call the “insertion loop.” This is in the β-sheet structured N-terminal lobe of the catalytic domain, a loop opposite the G-loop described in published studies as a critical structural element of all ePKs (Krupa et al., 2004). If a structure of the targeted catalytic domain is unavailable, one ca ...
Introduction Wnt signaling in development
... proliferation by regulating the expression of specific target genes and also controls cell polarity and migration by directly modulating the cytoskeleton (Cadigan and Nusse, 1997; Logan and Nusse, 2004). Studies in Drosophila and vertebrates have shown that these effects of Wnt are transduced by dif ...
... proliferation by regulating the expression of specific target genes and also controls cell polarity and migration by directly modulating the cytoskeleton (Cadigan and Nusse, 1997; Logan and Nusse, 2004). Studies in Drosophila and vertebrates have shown that these effects of Wnt are transduced by dif ...
Chapter 15
... Hexokinase is inhibited by product glucose-6-phosphate: by competition at the active site by allosteric interaction at a separate enzyme site. Cells trap glucose by phosphorylating it, preventing exit on glucose carriers. Product inhibition of Hexokinase ensures that cells will not continue to a ...
... Hexokinase is inhibited by product glucose-6-phosphate: by competition at the active site by allosteric interaction at a separate enzyme site. Cells trap glucose by phosphorylating it, preventing exit on glucose carriers. Product inhibition of Hexokinase ensures that cells will not continue to a ...
