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... disease brain (Yang et al., 1991a, 1993b) . The phosphorylation of T by protein kinase FA/GSK-3a also decreases T's affinity for microtubule and actin filament binding, suggesting a possible involvement in the functional regulation of the neuronal cytoskeletal system (Yang et al., 1993a) . Hanger et ...
Glycolysis and Gluconeogenesis
Glycolysis and Gluconeogenesis

...  Of what value is glycolysis for cells?  provides energy in form of ATP ...
Brucella Quorum Sensing: much more than
Brucella Quorum Sensing: much more than

... influence both Brucella virulence and metabolism. ...
Review: can diet influence the selective advantage of mitochondrial
Review: can diet influence the selective advantage of mitochondrial

Metabolomics - Circulation: Cardiovascular Genetics
Metabolomics - Circulation: Cardiovascular Genetics

... and cofactors across the impermeable mitochondrial inner membrane. These transport steps are important to maintain a separate inner mitochondrial pool and micromilieu for ATP production, for amino acid breakdown, for macromolecular and heme biosynthesis, and for heat generation. An example of such a ...
The Role of the Bundle Sheath in the Leaf Development of C3 plants
The Role of the Bundle Sheath in the Leaf Development of C3 plants

... remained elusive. Hence, we aimed at genetically cloning the affected gene. The gene was mapped to encode for ATase2, the first enzyme in de novo purine biosynthesis. The effect of the purine-derived phytohormone cytokinin on plant performance was assessed by growth kinetic analysis, cytokinin profi ...
Saccharomyces cerevisiae.
Saccharomyces cerevisiae.

... However, there are still organisms that can grow anaerobically, and even those that can survive under both conditions. The question is what the difference is between these organisms. Why can some grow only in the presence of molecular oxygen, some only in the absence, and are some able to withstand ...
Gene Section MUC4 (mucin 4, cell surface associated) in Oncology and Haematology
Gene Section MUC4 (mucin 4, cell surface associated) in Oncology and Haematology

... distal promoter is flanked by a TATA box located at 2672/-2668 and three transcriptional initiation sites at 2603, -2604 and -2605. Responsive regions and ciselements for transcription factors involved in Protein Kinase A, Protein Kinase C, cAMP signaling pathways, in inflammation (NF-kB) and in int ...
Biosynthesis of estradiol. Cloning and characterization of rodent
Biosynthesis of estradiol. Cloning and characterization of rodent

Taste bud - Science Mission
Taste bud - Science Mission

... Taste and smell: • Receptors are chemoreceptors • In association with food intake, influence flow of digestive juices and affect appetite • Stimulation of receptors induces pleasurable or objectionable sensations and signals presence of something to seek or to avoid ...
Identification and Analysis of Dicer Associated Proteins in
Identification and Analysis of Dicer Associated Proteins in

... complementarity, and either promote translational inhibition or degradation of their target mRNAs (for review see: (Filipowicz et al., 2005)). Foremost, the 5’ end of the miRNA, e.g. nt 2 to 8, shows almost perfect complementarity to its target site, and was termed a “seed region”. Functional miRNA ...
Regulation of the Escherichia coli Tryptophan Operon by Early
Regulation of the Escherichia coli Tryptophan Operon by Early

... 3-methylanthranilic acid (3MA) and 7-methylindole, cause derepression of the trp operon through feedback inhibition of anthranilate synthetase. Tyrosine reverses 3MA or 7-methylindole derepression, apparently by increasing the amount of chorismic acid available to the tryptophan pathway. A mutant is ...
Yeast lipid metabolism at a glance
Yeast lipid metabolism at a glance

A Theoretical Analysis of NADPH Production and
A Theoretical Analysis of NADPH Production and

... plant and fungal mitochondria (Palmer & Msller, 1982). The quantitative importance of this process in vivo is unknown. N A DPH-producing processes in yeasts The localization of NADPH-producing processes in the yeast cell is an important parameter since, as mentioned above, most NADPH-consuming proce ...
Co-translational Folding
Co-translational Folding

... and a newly formed protein is released. ...
PDQ Physiology
PDQ Physiology

... arrangements of the proteins α- and β-tubulin, 20 to 30 nm in diameter and 10 to 25 µm in length. They grow from one end (the plus end) by polymerization of tubulin, whereas the minus end tends to disintegrate by hydrolysis unless it is stabilized. Microtubules are present in almost all mammalian ce ...
SUC1 and SUC2: two sucrose transporters from Arabidopsis
SUC1 and SUC2: two sucrose transporters from Arabidopsis

Novel regulatory roles of omega-3 fatty acids in metabolic pathways
Novel regulatory roles of omega-3 fatty acids in metabolic pathways

... low n-3 PUFA diet (Figure 2B). These findings suggest that the regulation of lipid metabolism by n-3 PUFA is likely mediated via regucalcin, which is a novel finding. We also observed a higher expression of Apolipoprotein A-I (ApoA-I) in mice fed the high n-3 PUFA diet. ApoA-I is the major protein c ...
A 1-Megadalton Translocation Complex Containing
A 1-Megadalton Translocation Complex Containing

... located in the inner and outer envelope membranes. At the inner membrane, many Tic components have been identified and characterized, but it remains unclear how these Tic proteins are organized to form a protein-conducting channel or whether a stable Tic core complex that binds translocating preprot ...
Sugar Metabolism in Yeasts: an Overview of Aerobic and Anaerobic
Sugar Metabolism in Yeasts: an Overview of Aerobic and Anaerobic

Relations between Intracellular Ions and Energy Metabolism: A
Relations between Intracellular Ions and Energy Metabolism: A

Biochemistry 304 2014 Student Edition Glycolysis Lectures
Biochemistry 304 2014 Student Edition Glycolysis Lectures

... Hexokinase Control Hexokinase is inhibited by Glucose –6-P (its product). Indicates that the cell has sufficient energy supply. This will leave glucose in the blood. Special case of liver: glucokinase (an isozyme) not inhibited by glucose-6-P. Has a 50-fold LOWER affinity for glucose. Functions to ...
Enzymatic activation of sulfur for incorporation into biomolecules in
Enzymatic activation of sulfur for incorporation into biomolecules in

A role for interleukin-1 in epidermal differentiation
A role for interleukin-1 in epidermal differentiation

... IL-1 RI or IL-1 RII, the number of these receptors on keratinocytes in vitro was found to vary depending on culture conditions. Total receptor number decreased initially as keratinocyte cultures became confluent and more differentiated (Kupper et al., 1988), although induction of terminal differenti ...
Non-Regenerative Benefits of Adult Bone Marrow Derived Stem
Non-Regenerative Benefits of Adult Bone Marrow Derived Stem

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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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