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... generated from researchers through experiments performed in laboratory across the world. The gene H. sapiens in Entrez Gene (EG), amyloid beta (A4) precursor protein (APP) contain details and comprehensive information about gene and other related elements. Annotation data cross-reference database is ...
Lecture 3 HAEMOGLOBIN
Lecture 3 HAEMOGLOBIN

... The major switch from fetal to adult haemoglobin occurs 3-6 months after birth. 65% of Hb is synthesized in the erythroblast and 35 % at the reticulocyte stage. Haem synthesis occurs largely in the mitochondria by a series of biochemical reactions commencing with the condensation of glycine and suc ...
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Protein Structure & Function

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GPI Anchor
GPI Anchor

... 1. Proteins with a terminal Leu are modified by an isoprenyltransferase that transfers from geranylgeranyl pyrophosphate to Cys. Proteins with terminal residues, Ser, Ala, Met, or Gln are modified by another enzyme that adds farnesyl pyrophosphate to Cys. 2. Following the attachment of the isoprenyl ...
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Introduction to the Cardiovascular System

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Protein Structure & Function - Lectures For UG-5
Protein Structure & Function - Lectures For UG-5

... the enzyme early in the pathway ...
Appendix Definitions ACTH: see adrenocorticotrophic hormone
Appendix Definitions ACTH: see adrenocorticotrophic hormone

... Heat shock proteins play roles in folding newly produced and denatured proteins, and in transporting proteins across membranes within the cell. The heat shock proteins are divided into several families based on similarities of sequence and function: hsp60, hsp70, and hsp90 are the most well characte ...
Glucose/Galactose Binding Protein (GGBP)
Glucose/Galactose Binding Protein (GGBP)

... charged RD pocket by 3-4 Å upon phosphorylation or mutation to a glutamic acid. The phosphorylated amino acid is also subject to a much more restrictive potential of mean force over the coordinate between S179 and the RD pocket. The simulation results will be further contextualized in terms of the l ...
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Chapter 12. Regulation of the Cell Cycle - Environmental

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... identified as Hh pathway components: a cell surface protein (Dally-like protein) required for Hh signal reception, and casein kinase 1␣, a candidate tumor suppressor that regulates basal activities of both Hh and Wg pathways. This type of cultured cell– based functional genomics approach may be usefu ...
Cell Biology Revision Notes
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Maize Metabolic Network Construction and Transcriptome Analysis

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...  The presence of factors within target cell necessary for the response.  Up- or down-regulation of the receptor.  Post-receptor desensitization of the cell >> down-regulation. ** There’re molecules within the target cell; such as co-repressors & co-activators, that might activate or inhibit the m ...
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Retinoic acid (R2625) - Product Information Sheet - Sigma

... act as a type of signal molecule working through a nuclear receptor in the regulation of region differentiation of the central nervous system.16 RA induces morphological and functional terminal differentiation of a cell line of human promyelocyte leukemia at 1 nM (maximal differentiation at 1 µM)14 ...
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GeneCensus - Gerstein Lab Publications
GeneCensus - Gerstein Lab Publications

... the genomes(10). These characteristics include broad statistics, such as fold and gene content and amino acid composition. The trees that we provide can be compared against other information, and dynamically reconfigured based on different genomic characteristics. Our second viewer, PathwayPainter, ...
(Semester VI) Paper 15: PLANT METABOLISM THEORY Unit 1
(Semester VI) Paper 15: PLANT METABOLISM THEORY Unit 1

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RTRI Cellular Respiration
RTRI Cellular Respiration

... A complex network of chemical reactions are continually at work in cells in order to sustain life. These reactions form the basis of metabolism and are organized into an interconnected series of reactions called metabolic pathways (Figure1). The operation of these pathways is made possible by enzyme ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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