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A glucose-responsive transcription factor that regulates
A glucose-responsive transcription factor that regulates

Nitrate signaling via Abscisic Acid release from
Nitrate signaling via Abscisic Acid release from

... growth in response. Root growth is exquisitely sensitive to changes in environmental nitrate, either inhibiting or stimulating growth depending on concentration, location and physiological context. Root branching in response to local nitrate signals had been previously shown to require abscisic acid ...
I Biology I Lecture Outline 5 The Cell
I Biology I Lecture Outline 5 The Cell

... a) Are capable of direl.:tly carrying out and fos tering metabolic reactions b) These are actually enzymes attached to the plasma membrane as opposed to independently 'poating around" in the cytoplasm ...
Biochemistry 3020 1. The consumption of
Biochemistry 3020 1. The consumption of

... Regenerates NAD+ from NADH (reducing equivalents) produced in glycolysis. Lactate fermentation is important in red blood cells, parts of the retina and in skeletal muscle cells during extreme high activity. Also important in plants and microbes growing in absence of O2. ...
Protein-Protein Interactions
Protein-Protein Interactions

... Modifications: Covalent modification of proteins can prevent or induce binding of others. Examples are proteins that contain the so-called bromo domain that binds only acetylated but not unmodified histones. Ligands: Small molecules or other proteins can regulate protein interactions. For example, b ...
Lecture 1 Course overview and intro to enzymes
Lecture 1 Course overview and intro to enzymes

... ΔG ‡ : the free energy of activation effect of enzyme on ΔG ‡ Computing the effect of changing ΔG ‡ on a reaction rate ed/RH as a multiplicative factor Ligand binding: features and the Kd Relation of binding isotherms to Kd and Bmax Viewing enzyme action as a process started by binding Michaelis-Men ...
Role of the ubiquitinselective CDC48UFD1/NPL4 chaperone
Role of the ubiquitinselective CDC48UFD1/NPL4 chaperone

... found that CDC48UFD1/NPL4 plays a second role in the OLE pathway by mediating ERAD of OLE1. Intriguingly, other ERAD substrates also require CDC48UFD1/NPL4 for degradation, indicating that this enzyme is a novel, constitutive component of the ERAD machinery. We propose that CDC48UFD1/NPL4 functions ...
The heterochronic gene lin-29 encodes a zinc finger protein that
The heterochronic gene lin-29 encodes a zinc finger protein that

... temporal control of cell division, differentiation and morphogenesis in diverse cell types. The timing of particular developmental events is ultimately specified by the stage-specific control of gene expression; therefore temporal coordination of complex developmental sequences must involve an organ ...
Nuclear and mitochondrial forms of human uracil
Nuclear and mitochondrial forms of human uracil

... not shown), while the corresponding cytoplasmic UDG activity peaked in die presence of 60 mM NaCl. Furthermore, in vitrotranscription/translation experiments indicated that the specific activity of the UNG-protein closely corresponding to the mature form, is 4—5 times higher man die corresponding fu ...
Analysis of hepatocyte nuclear factor
Analysis of hepatocyte nuclear factor

... mutations which eliminated two conserved casein kinase I sites or increased the number of acidic amino acid residues in the N-terminal domain. Furthermore, we determined that the nuclear localization signal overlaps with the winged helix DNA-binding motif. These results suggest that conserved sequen ...
Secondary Products
Secondary Products

... Often have a lactone ring Gossypol in cotton responsible for insect resistance in some varieties (possible new spermicide) Artemisinin produced by Artemesia annua ...
Final Respiration
Final Respiration

... • Compare the kilocalories of glucose with the kilocalories in the ATP that is made. • The 2 ATP molecules made during glycolysis account for only 2% of the energy in glucose • Where does the rest go? • It’s still in pyruvic acid • This small amount of energy is enough for ...
cellrespdiagrams
cellrespdiagrams

... • Compare the kilocalories of glucose with the kilocalories in the ATP that is made. • The 2 ATP molecules made during glycolysis account for only 2% of the energy in glucose • Where does the rest go? • It’s still in pyruvic acid • This small amount of energy is enough for ...
Final Respiration
Final Respiration

... • Compare the kilocalories of glucose with the kilocalories in the ATP that is made. • The 2 ATP molecules made during glycolysis account for only 2% of the energy in glucose • Where does the rest go? • It’s still in pyruvic acid • This small amount of energy is enough for ...
ATP powers cellular work
ATP powers cellular work

... cells use up the oxygen Muscle cells switch over to making ATP by fermentation ...
protein metabolism - cmb
protein metabolism - cmb

... plot of isotope remaining in a protein versus time is linear. Thus, we can determine the metabolic half-life of a particular protein. In a rat the average protein has a half-life of 1 or 2 days. ...
Uncoupling Proteins Cellular Metabolism Cellular Metabolism
Uncoupling Proteins Cellular Metabolism Cellular Metabolism

... •  Weight loss ⇒ more efficient lipogenesis ⇒ regain lost fat ...
LowSlides
LowSlides

... non-RECEPTOR TYROSINE KINASE (JAK) “2ND MESSENGER” CASCADES ...
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Slide 1
Slide 1

... pathways that produce acetyl-CoA for different metabolic functions  How glucose and glutamine derived C2 units are maintained as functionally distinct pools and transported from their respective organelles to different sites of acetylation remains to be investigated  The metabolic labeling data su ...
The Photosynthetic Dark Reactions Do Not Operate
The Photosynthetic Dark Reactions Do Not Operate

... of the light reactions?’’ The standard answer is that the light reactions provide the necessary ATP and NADPH (source of electrons) for the creation of sugars in the subsequent Calvin cycle reactions. It is logical to conclude that the Calvin reactions would not be operational in the absence of ligh ...
T-cell metabolism in autoimmune disease
T-cell metabolism in autoimmune disease

... in producing ATP. The end product of glycolysis, pyruvate, is imported into the mitochondria, decarboxylated to acetyl-coenzyme A (CoA), and then condensed with oxaloacetate to form citrate. Citrate can be exported from the mitochondria via the malate–citrate shuttle system and used as a substrate f ...
Cellular Respiration
Cellular Respiration

... hydrogen and its bonding electrons change partners Hydrogen and its electrons go from sugar to oxygen, forming water ...
2t.7 Cellular work
2t.7 Cellular work

... Some phosphorylated enzyme substrates are activated for subsequent reactions they would not ordinarily undergo. The process of activation often involves a coupled reaction-an energeticallyunfauorable reaction is made to occur by being linked to a reaction that is energetically ueryfauorable (uery ex ...
Datasheet - Sigma
Datasheet - Sigma

... 3. Sporn, M.B., and Roberts, A.B., eds. Peptide Growth Factors and Their Receptors, SpringerVerlang Heidelberg, Vol. II, pp 217-235 (1991). 4. De Jong, F., et al., Effects of factors from ovarian follicular fluid and Sertoli cell culture medium on invivo and in-vitro release of pituitary gonadotroph ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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