Human epidermal growth factor receptor (HER-1:HER
... The human epidermal growth factor (EGF) receptor (HER) family is composed of EGFR/HER-1/ErbB1, HER-2/ErbB2, HER-3/ErbB3, and HER-4/ErbB4 (1 – 3). This family of proteins share common structural features consisting of an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic k ...
... The human epidermal growth factor (EGF) receptor (HER) family is composed of EGFR/HER-1/ErbB1, HER-2/ErbB2, HER-3/ErbB3, and HER-4/ErbB4 (1 – 3). This family of proteins share common structural features consisting of an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic k ...
Module Outline
... Chapter 8 Harvesting chemical energy: Cellular respiration. a) Describe energy flow through ecosystems (p. 162, Fig 8.1) b) Describe how catabolism releases energy by oxidation of organic fuels (pp. 162-165) c) Identify the reduced and oxidized components of a given reaction (p. 163, Fig. 8.2) d) D ...
... Chapter 8 Harvesting chemical energy: Cellular respiration. a) Describe energy flow through ecosystems (p. 162, Fig 8.1) b) Describe how catabolism releases energy by oxidation of organic fuels (pp. 162-165) c) Identify the reduced and oxidized components of a given reaction (p. 163, Fig. 8.2) d) D ...
top408b1_2006
... -KG: Proline biosynthesis was done according to Fig 25.20, page 824. Most texts merge the first two steps into a "Kinase D.H." but learn it as shown here. G.S.A. spontaneously cyclizes, forming a Schiff base, which can then be reduced to give Pro. The Orn pathway (Fig 25.21, p. 825) is similar in m ...
... -KG: Proline biosynthesis was done according to Fig 25.20, page 824. Most texts merge the first two steps into a "Kinase D.H." but learn it as shown here. G.S.A. spontaneously cyclizes, forming a Schiff base, which can then be reduced to give Pro. The Orn pathway (Fig 25.21, p. 825) is similar in m ...
DEFINITIONS - bums.ac.ir
... Immunoglobulins:Structure and Function • Definition: Glycoprotein molecules that are produced by plasma cells in response to an immunogen and which function as antibodies ...
... Immunoglobulins:Structure and Function • Definition: Glycoprotein molecules that are produced by plasma cells in response to an immunogen and which function as antibodies ...
Document
... Relate sample size to both validity and reproducibility Recognise and terms ‘mean’ ‘median’ and ‘mode’ ...
... Relate sample size to both validity and reproducibility Recognise and terms ‘mean’ ‘median’ and ‘mode’ ...
26491 Discuss the cellular metabolism of glucose, amino
... Discuss the role of adenosine triphosphate (ATP) in metabolism. Evidence requirements ...
... Discuss the role of adenosine triphosphate (ATP) in metabolism. Evidence requirements ...
Janeway`s Immunobiology, 9th Edition Chapter 2: Innate Immunity
... constitutively produced recognition molecules that directly interact with microbial surfaces. B. When the complement cascade leads to the formation of a membrane-attack complex, the pathogen is killed. C. Several of the soluble products generated by complement activation lead promote the inflammator ...
... constitutively produced recognition molecules that directly interact with microbial surfaces. B. When the complement cascade leads to the formation of a membrane-attack complex, the pathogen is killed. C. Several of the soluble products generated by complement activation lead promote the inflammator ...
Steroid hormone receptor homologs in development
... has a more complex distribution, being highest in the brain, kidney and prostate (deThe et al. 1989). By analogy with steroid receptors, a potential model for transmission of positional information via the morphogen retinoic acid is through the two retinoic acid receptors. Upon ligand binding, the r ...
... has a more complex distribution, being highest in the brain, kidney and prostate (deThe et al. 1989). By analogy with steroid receptors, a potential model for transmission of positional information via the morphogen retinoic acid is through the two retinoic acid receptors. Upon ligand binding, the r ...
Sample Preparation I (Protein Purification)
... strategy: you will need to do some prep so that the lipids and/or sugars will not interfere with downstream experiments “It’s in the blood” – Ok! One of the most common proteins in blood is hemoglobin. It is so abundant that it may interfere as well as the iron! strategy: remove hemoglobin by affini ...
... strategy: you will need to do some prep so that the lipids and/or sugars will not interfere with downstream experiments “It’s in the blood” – Ok! One of the most common proteins in blood is hemoglobin. It is so abundant that it may interfere as well as the iron! strategy: remove hemoglobin by affini ...
Protein oxidation and cellular homeostasis: Emphasis
... SOH. The main consequences of these ROS appears to be alterations to DNA strands, and the generation of 8-hydroxydeoxyguanosine (8-OHdG) [26,27]. Furthermore, these species can interfere with the metabolism of collagen, down regulating collagen synthesis and contribute to potentially deleterious col ...
... SOH. The main consequences of these ROS appears to be alterations to DNA strands, and the generation of 8-hydroxydeoxyguanosine (8-OHdG) [26,27]. Furthermore, these species can interfere with the metabolism of collagen, down regulating collagen synthesis and contribute to potentially deleterious col ...
Cellular Pathophysiology of Insulin Resistance
... Poretsky LO, ed. New York, Springer,2009, p. 75-87. ...
... Poretsky LO, ed. New York, Springer,2009, p. 75-87. ...
Impact of Ischemia on Cellular Metabolism
... The mitochondrial calcium concentration is in equilibrium between its cytosolic concentration and the proton gradient on either side of the inner membrane of mitochondria. The loss of this gradient due to the inhibition of the respiratory chain, as well as the elevated cytosolic calcium that results ...
... The mitochondrial calcium concentration is in equilibrium between its cytosolic concentration and the proton gradient on either side of the inner membrane of mitochondria. The loss of this gradient due to the inhibition of the respiratory chain, as well as the elevated cytosolic calcium that results ...
doc
... ULG2 studies the scaffold protein TANK/I-TRAF, which is a TRAF2 and IKK-interacting protein that is required for the TNF-induced and NF-B-dependent expression of a selection of target genes (Bonif et al., 2006). The fact that TANK also binds TBK1 and IKK kinases, which are essential components of ...
... ULG2 studies the scaffold protein TANK/I-TRAF, which is a TRAF2 and IKK-interacting protein that is required for the TNF-induced and NF-B-dependent expression of a selection of target genes (Bonif et al., 2006). The fact that TANK also binds TBK1 and IKK kinases, which are essential components of ...
Integrins and cell differentiation
... Altogether, these results lead to a model in which integrinmediated adhesion plays a role in regulating tendon cell differentiation by modulating the activity of the Egfr pathway at the level of its ligand Vein. ...
... Altogether, these results lead to a model in which integrinmediated adhesion plays a role in regulating tendon cell differentiation by modulating the activity of the Egfr pathway at the level of its ligand Vein. ...
Pentose phosphate pathway (hexose monophosphate shunt)
... • Generation of NADPH ‐ mainly used for reductive syntheses of fatty acids, steroids, amino acids via glutamate dehydrogenase; and production of reduced glutathione in erythrocytes and other cells. ‐ active in liver, adipose tissue, adrenal cortex, thyroid, erythrocytes, testes, and lactating ma ...
... • Generation of NADPH ‐ mainly used for reductive syntheses of fatty acids, steroids, amino acids via glutamate dehydrogenase; and production of reduced glutathione in erythrocytes and other cells. ‐ active in liver, adipose tissue, adrenal cortex, thyroid, erythrocytes, testes, and lactating ma ...
In-vivo detection of binary PKA network interactions upon activation
... the pathological cell condition, specifically PPIs emanating from GTPases and kinases4,16,25,26. A simple PPI reporter assay that can be used in different model systems would be convenient for drug discovery in several respects. Besides the quantification of selected wild type and mutationally modif ...
... the pathological cell condition, specifically PPIs emanating from GTPases and kinases4,16,25,26. A simple PPI reporter assay that can be used in different model systems would be convenient for drug discovery in several respects. Besides the quantification of selected wild type and mutationally modif ...
BT02D04 - 09.21.10 - Cell Respiration Continued
... – They have enough ATP to support activities such as quick sprinting for about 5 seconds – A secondary supply of energy (creatine phosphate) can keep muscle cells going for ...
... – They have enough ATP to support activities such as quick sprinting for about 5 seconds – A secondary supply of energy (creatine phosphate) can keep muscle cells going for ...
Biosynthesis of the dystonia-associated AAA ATPase torsinA at the
... twenty times through a ball bearing cell cracker. The resulting homogenate was resuspended in 900 µl of either 25 mM CAPSO ...
... twenty times through a ball bearing cell cracker. The resulting homogenate was resuspended in 900 µl of either 25 mM CAPSO ...
7.014 Quiz I Handout
... i) What is the Keq for the coupled reaction (4) in terms of the Keq of reaction (2), at 25° C? Show your work. ...
... i) What is the Keq for the coupled reaction (4) in terms of the Keq of reaction (2), at 25° C? Show your work. ...
12.1 Mechanisms regulating enzyme synthesis 12.1.2.2 Enzyme
... The regulatory gene (lacI) next to the 5’ end of the operon is expressed constitutively with its own promoter. In the absence of the inducer, the LacI protein binds the operator region of the lac operon, inhibiting RNA polymerase from binding the promoter region. When the inducer (lactose or I ...
... The regulatory gene (lacI) next to the 5’ end of the operon is expressed constitutively with its own promoter. In the absence of the inducer, the LacI protein binds the operator region of the lac operon, inhibiting RNA polymerase from binding the promoter region. When the inducer (lactose or I ...
In vitro biological activities of Douglas fir essential oil in
... biomarker “key activity,” as DEO-induced changes in their expression levels were significantly different (p < 0.05) from those in vehicle-treated controls with an effect size of at least 10% (more than 0.05 log ratio units). MCP-1, monocyte chemoattractant protein; VCAM-1, vascular cell adhesion mol ...
... biomarker “key activity,” as DEO-induced changes in their expression levels were significantly different (p < 0.05) from those in vehicle-treated controls with an effect size of at least 10% (more than 0.05 log ratio units). MCP-1, monocyte chemoattractant protein; VCAM-1, vascular cell adhesion mol ...