Degradation of fluorobenzene by Rhizobiales strain F11 via
... place already during the initial period of FB degradation, i.e., when catechol is formed but that fluoride release is only complete when the intermediate 4-fluorocatechol and possibly other fluorinated metabolites have been degraded. The formation of both catechol and 4-fluorocatechol from FB is als ...
... place already during the initial period of FB degradation, i.e., when catechol is formed but that fluoride release is only complete when the intermediate 4-fluorocatechol and possibly other fluorinated metabolites have been degraded. The formation of both catechol and 4-fluorocatechol from FB is als ...
Aplysia
... The efficacy of synaptic transmission in the brain is activity-dependent and continuously modified. Examples of such persistent modification is long-term potentiation and depression (LTP and LTD). ...
... The efficacy of synaptic transmission in the brain is activity-dependent and continuously modified. Examples of such persistent modification is long-term potentiation and depression (LTP and LTD). ...
Simple Models of Protein Folding
... Otherwise, the value of < ρ > may approach 1, but the value for ρ∗ may approach 1 through one or two steps, corresponding to a first-order folding transition or transition through a folding intermediate respectively. Now, specifically for the ten monomer chain, there are 1024 possible sequences. Of ...
... Otherwise, the value of < ρ > may approach 1, but the value for ρ∗ may approach 1 through one or two steps, corresponding to a first-order folding transition or transition through a folding intermediate respectively. Now, specifically for the ten monomer chain, there are 1024 possible sequences. Of ...
Protein kinase A
... ADP/ATP ratio is high enough so that ATP-sensitive potassium channels (KATP) are open, and the membrane potential is about 70 mv. Voltage-sensitive calcium channels (VSCC) and calciumsensitive potassium channels (CSKC) are closed. B. Beta cell response to increased blood glucose. Increased entry an ...
... ADP/ATP ratio is high enough so that ATP-sensitive potassium channels (KATP) are open, and the membrane potential is about 70 mv. Voltage-sensitive calcium channels (VSCC) and calciumsensitive potassium channels (CSKC) are closed. B. Beta cell response to increased blood glucose. Increased entry an ...
Chapter.ID_42624_6x9_GMcB
... work has shown that both the exchanger and the regulatory enzyme of GSH synthesis, -glutamate cysteine ligase (GCL) are under transcriptional control by nuclear factor (erythroid-derived 2)-like 2 (Nrf2). This transcription factor, often dubbed the ‘master regulator’ of antioxidant pathways, is its ...
... work has shown that both the exchanger and the regulatory enzyme of GSH synthesis, -glutamate cysteine ligase (GCL) are under transcriptional control by nuclear factor (erythroid-derived 2)-like 2 (Nrf2). This transcription factor, often dubbed the ‘master regulator’ of antioxidant pathways, is its ...
TGF-β/BMP superfamily members, Gbb-60A and Dpp
... to generate clones of cells null for gbb-60A function in the imaginal discs (Fig. 2D-G). Consistent with a potential role for gbb-60A in proliferation, gbb-60A null clones are never recovered in the adult wing if induced during the early period of cell proliferation (before 36 hours AEL); however, c ...
... to generate clones of cells null for gbb-60A function in the imaginal discs (Fig. 2D-G). Consistent with a potential role for gbb-60A in proliferation, gbb-60A null clones are never recovered in the adult wing if induced during the early period of cell proliferation (before 36 hours AEL); however, c ...
Characterization of the Plasmid-Encoded Arsenic Salts Resistance
... Both the N-terminal and C-terminal contained the glycinerich clusters, G15KGGVGKTS23 and G335KRCVGKT343, suggesting that the ArsA protein is the catalytic subunit of an arsenate-translocating ATPase [4]. The predicted ArsA protein also contained two independent domains with 32% homology, possibly du ...
... Both the N-terminal and C-terminal contained the glycinerich clusters, G15KGGVGKTS23 and G335KRCVGKT343, suggesting that the ArsA protein is the catalytic subunit of an arsenate-translocating ATPase [4]. The predicted ArsA protein also contained two independent domains with 32% homology, possibly du ...
Biochem Chapter 44 [4-20
... The ATP is used for ion transport across the cell membrane, phosphorylation of membrane proteins, and priming rxns of glycolysis RBC glycolysis uses the Rapoport-Luebering shunt to generate 2,3-bisphosphoglycerate (2,3BPG) o RBCs have way more 2,3-BPG than other cells o 2,3-BPG is needed for the pho ...
... The ATP is used for ion transport across the cell membrane, phosphorylation of membrane proteins, and priming rxns of glycolysis RBC glycolysis uses the Rapoport-Luebering shunt to generate 2,3-bisphosphoglycerate (2,3BPG) o RBCs have way more 2,3-BPG than other cells o 2,3-BPG is needed for the pho ...
Final a
... 5. (8pts) Draw a balanced equation for the overall reaction mediated by the Calvin cycle, assuming the production of one glucose molecule from carbon dioxide. How many turnovers are required from Rubisco for each glucose produced? ...
... 5. (8pts) Draw a balanced equation for the overall reaction mediated by the Calvin cycle, assuming the production of one glucose molecule from carbon dioxide. How many turnovers are required from Rubisco for each glucose produced? ...
Engineering of metabolic pathways by artificial enzyme channels
... steps starting from tyrosine. In Sorghum bicolor, these reactions are catalyzed by two multifunctional enzymes and one monofunctional enzyme that form a metabolic channel. The importance of this channel became evident in transgenic Arabidopsis plants expressing only the two first enzymes of the path ...
... steps starting from tyrosine. In Sorghum bicolor, these reactions are catalyzed by two multifunctional enzymes and one monofunctional enzyme that form a metabolic channel. The importance of this channel became evident in transgenic Arabidopsis plants expressing only the two first enzymes of the path ...
INTRODUCTION
... maintaining mitochondrial quality control. Fission allows separation of the healthy mitochondrial segments from the defective ones. Not surprising then, failure to transition between the different morphological forms is thought to contribute to several diseases e.g. Parkinsons disease: see later. An ...
... maintaining mitochondrial quality control. Fission allows separation of the healthy mitochondrial segments from the defective ones. Not surprising then, failure to transition between the different morphological forms is thought to contribute to several diseases e.g. Parkinsons disease: see later. An ...
Identification of Plant Virus Movement-Host Protein
... structural protein, termed NSm, is translated from this cistron and that this protein represents the MP of the Tospoviruses (Kormelink et al., 1994). It is still a m atter of discussion whether the appearance of this specified additional cistron opened the door to attack organisms of the plant kingd ...
... structural protein, termed NSm, is translated from this cistron and that this protein represents the MP of the Tospoviruses (Kormelink et al., 1994). It is still a m atter of discussion whether the appearance of this specified additional cistron opened the door to attack organisms of the plant kingd ...
Identification of Plant Virus Movement
... structural protein, termed NSm, is translated from this cistron and that this protein represents the MP of the Tospoviruses (Kormelink et al., 1994). It is still a m atter of discussion whether the appearance of this specified additional cistron opened the door to attack organisms of the plant kingd ...
... structural protein, termed NSm, is translated from this cistron and that this protein represents the MP of the Tospoviruses (Kormelink et al., 1994). It is still a m atter of discussion whether the appearance of this specified additional cistron opened the door to attack organisms of the plant kingd ...
Function and specificity of 14-3-3 proteins in the regulation of
... 1993; Toroser and Huber, 1997). However, there is a sitespeci®c regulatory interaction between 14-3-3 proteins and Ser-229 of spinach SPS which inhibits SPS activity (Toroser et al., 1998). The interaction of 14-3-3s and target proteins can be reduced in vitro by 5¢-AMP which interacts with 14-3-3s ...
... 1993; Toroser and Huber, 1997). However, there is a sitespeci®c regulatory interaction between 14-3-3 proteins and Ser-229 of spinach SPS which inhibits SPS activity (Toroser et al., 1998). The interaction of 14-3-3s and target proteins can be reduced in vitro by 5¢-AMP which interacts with 14-3-3s ...
Protein Solubility as Quality Index for Processed Soybean (PDF
... availability. Protein digestibility is a major index of protein quality because a certain amount of amino-acids may be present in a food and it may not necessarily be available to the organism for nourishment. This means proteins cannot be utilized unless they are digested [3]. The differences in pr ...
... availability. Protein digestibility is a major index of protein quality because a certain amount of amino-acids may be present in a food and it may not necessarily be available to the organism for nourishment. This means proteins cannot be utilized unless they are digested [3]. The differences in pr ...
1 Cholesterol synthesis, uptake, and regulation I. Structure and
... fact that in people with Neeman-Pick’s type C disease, cholesterol gets stuck in their lysosomes. Since the disease is caused by a genetic mutation, the machine for exporting cholesterol from lysosomes must involve a protein. This protein contains multiple transmembrane domains, collectively known a ...
... fact that in people with Neeman-Pick’s type C disease, cholesterol gets stuck in their lysosomes. Since the disease is caused by a genetic mutation, the machine for exporting cholesterol from lysosomes must involve a protein. This protein contains multiple transmembrane domains, collectively known a ...
Systems Biology of Biological Nitrogen Fixation
... the role that glycogen could be playing during nodulation of legumes, however, it has been reported that in R. tropici, glycogen synthase (glgA) mutants have increased respiratory capacities and enhanced symbiotic performance [29]. Glycogen as PHB synthesis in free-living cells, are accumulated unde ...
... the role that glycogen could be playing during nodulation of legumes, however, it has been reported that in R. tropici, glycogen synthase (glgA) mutants have increased respiratory capacities and enhanced symbiotic performance [29]. Glycogen as PHB synthesis in free-living cells, are accumulated unde ...
Chapter 6 Proteins & Amino Acids
... Risk of colon cancer Displacement of other nutrient-rich, disease preventing foods ...
... Risk of colon cancer Displacement of other nutrient-rich, disease preventing foods ...
Lecture 0 - Introduction - LCQB
... • Algorithm in structural bioinformatics can help predict and classify protein structures, describe their motions and interactions, design new drugs. ...
... • Algorithm in structural bioinformatics can help predict and classify protein structures, describe their motions and interactions, design new drugs. ...
Structural Bioinformatics - LCQB
... The conformation of the whole main chain of the polypeptide is completely determined when the rotation angles φ (N-Cα) and ψ = (CαC’) are defined with high accuracy. ...
... The conformation of the whole main chain of the polypeptide is completely determined when the rotation angles φ (N-Cα) and ψ = (CαC’) are defined with high accuracy. ...
Yeast Display Evolution of a Kinetically Efficient 13-Amino
... a conserved β-hairpin structure, a conformation that is difficult to recapitulate in a peptide, and thus we performed in vitro evolution to engineer the LplA peptide substrate, called “LplA Acceptor Peptide” (LAP). A ∼107 library of LAP variants was displayed on the surface of yeast cells, labeled b ...
... a conserved β-hairpin structure, a conformation that is difficult to recapitulate in a peptide, and thus we performed in vitro evolution to engineer the LplA peptide substrate, called “LplA Acceptor Peptide” (LAP). A ∼107 library of LAP variants was displayed on the surface of yeast cells, labeled b ...
tr-kit promotes the formation of a multimolecular complex composed
... carboxyl-terminal domain and it is the main substrate for Src-like kinases in mitosis (Taylor and Shalloway, 1994); it has been demonstrated that the interaction with the SH3 domain of Fyn is necessary for Fyn-dependent tyrosine phosphorylation of Sam68 (Shen et al., 1999). Once phosphorylated in th ...
... carboxyl-terminal domain and it is the main substrate for Src-like kinases in mitosis (Taylor and Shalloway, 1994); it has been demonstrated that the interaction with the SH3 domain of Fyn is necessary for Fyn-dependent tyrosine phosphorylation of Sam68 (Shen et al., 1999). Once phosphorylated in th ...
Impact of Ischemia on Cellular Metabolism
... The mitochondrial calcium concentration is in equilibrium between its cytosolic concentration and the proton gradient on either side of the inner membrane of mitochondria. The loss of this gradient due to the inhibition of the respiratory chain, as well as the elevated cytosolic calcium that results ...
... The mitochondrial calcium concentration is in equilibrium between its cytosolic concentration and the proton gradient on either side of the inner membrane of mitochondria. The loss of this gradient due to the inhibition of the respiratory chain, as well as the elevated cytosolic calcium that results ...
Chapter 8
... In comparison to de novo pathway, salvage pathway is energy-saving. In brain and bone marrow tissues salvage pathway is the only pathway of nucleotide synthesis. Deficiency of HGPRT causes Lesch Nyhan syndrome. ...
... In comparison to de novo pathway, salvage pathway is energy-saving. In brain and bone marrow tissues salvage pathway is the only pathway of nucleotide synthesis. Deficiency of HGPRT causes Lesch Nyhan syndrome. ...
Cardiovascular Effects of Androgens
... At the cellular level, cardiomyocytes depend of the activation of several signalling pathways related to cell growth, which are crucial for the development of cardiac hypertrophy. These pathways involve both androgen receptors as well as intracellular signalling pathways. 4.1 Androgen receptor in hy ...
... At the cellular level, cardiomyocytes depend of the activation of several signalling pathways related to cell growth, which are crucial for the development of cardiac hypertrophy. These pathways involve both androgen receptors as well as intracellular signalling pathways. 4.1 Androgen receptor in hy ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.