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Antioxidant activities of dithiol alpha
Antioxidant activities of dithiol alpha

... Figure 2: Mechanism of action of lipoic acid. LA and/or DHLA may acts as a metal chelators, antioxidants or intracellular thiol modifying agents. LA is reduced intracellularly either by mitochondrial lipoamide dehydrogenase or by the thioredoxin/thioredoxin reductase system, using NAD(P)H as the red ...
Molecular architecture of the pyruvate dehydrogenase complex
Molecular architecture of the pyruvate dehydrogenase complex

... a second molecule of E2-SBD with either E1 or E3 is not possible. Occupation of both binding sites would result in steric clashes in one of the E2-SBD loop regions. In contrast, it has been known for a long time that a total of 30 E1 and six E3 molecules can associate with the mammalian PDC core [22 ...
ADP
ADP

... – Undergo through four times of dehydrogenation, two times of decarboxylation, one time of substrate level phosphorylation – Yield one molecule of FADH2, three molecules of NADH+H+, two molecules of CO2, one molecule of GTP. – Key enyzmes: citrate synthase α-ketoglutarate dehydrogenase complex isoci ...
Role of branched-chain amino acid transporters in Staphylococcus
Role of branched-chain amino acid transporters in Staphylococcus

Role of the glutamine transaminase-m-amidase
Role of the glutamine transaminase-m-amidase

... Keywords : Rhipbium etli, glutamine transaminase, o-amidase, glutaminase, catabolism, symbiosis ...
Facultative Anaerobiosis in the Invertebrates: Pathways and Control
Facultative Anaerobiosis in the Invertebrates: Pathways and Control

... from succinate include Ascaris lurnbricoides, Heterakis gallinae, Trichuris vulpis, and the larval form of Trichinclla spirails. Cestodes which also show this property include the tapeworms Hymenolepis diminuta and Moniezia expansa, and cysts of Echinococcus granulosus and Taeiiia taeniaformis. The ...
Proteomic sensitivity to dietary manipulations in rainbow trout
Proteomic sensitivity to dietary manipulations in rainbow trout

... fish. A proteomics approach was used to study the protein profiles of livers of rainbow trout that have been fed two diets containing different proportions of plant ingredients. Both diets control (C) and soy (S) contained fish meal and plant ingredients and synthetic amino acids, but diet S had a g ...
Chapter 8 Cellular Respiration 8.1 Cellular Respiration 1. Cellular
Chapter 8 Cellular Respiration 8.1 Cellular Respiration 1. Cellular

... e. The size of the Regroup determines the number of carbons left after deamination. B. Anabolism 1. ATP produced during catabolism drives anabolism. 2. Substrates making up pathways can be used as starting materials for synthetic reactions. 3. The molecules used for biosynthesis constitute the cell’ ...
Chapter 8 Cellular Respiration Dr. Harold Kay Njemanze 8.1
Chapter 8 Cellular Respiration Dr. Harold Kay Njemanze 8.1

... e. The size of the Regroup determines the number of carbons left after deamination. B. Anabolism 1. ATP produced during catabolism drives anabolism. 2. Substrates making up pathways can be used as starting materials for synthetic reactions. 3. The molecules used for biosynthesis constitute the cell’ ...
Fatty acid
Fatty acid

... • All living things are made up of four classes of large biological molecules: carbohydrates, lipids, proteins, and nucleic acids • Within cells, small organic molecules are joined together to form larger molecules • Macromolecules are large molecules ...
Principles of BIOCHEMISTRY
Principles of BIOCHEMISTRY

... liver, kidneys, and small intestine (小腸) and exported to the ...
Nucleic acid enzymes
Nucleic acid enzymes

... for this enzyme (Figure 1). The selected catalysts mediate urea bond formation at the N terminus of the peptides and differentiate between substrates with the opposite configuration to the C-terminal residue. Ribozymes able to synthesize purine nucleotides have been selected [18]. Together with the ...
Metabolite and isotopologue profiling in plants. Studies on the
Metabolite and isotopologue profiling in plants. Studies on the

... I thank Ms. Eva Eylert and Dr. Claudia Huber for assisting me with the analysis of my probes by GC-MS spectrometry and for their friendly attitude. My sincere thanks to Mr. Christoph Graßberger for maintaining a warm and friendly atmosphere in our lab, for helping me with many things, for amazing p ...
Regulation of Phenylalanine and Tyrosine
Regulation of Phenylalanine and Tyrosine

... hyperbolic with K , values of 0.31 r n M for chorismate and 0.015 mM for prephenate, respectively. The substrate saturation curve of the complexed prephenate dehydratase I was sigmoid; a Km value of 0-18 mM was calculated for prephenate. Chorismate mutase, prephenate dehydratase and prephenate dehyd ...
Pathways of ethanol production from sucrose by a
Pathways of ethanol production from sucrose by a

... A mutant (strain LLD-15) of Bacillus stearothevmuphihs strain LLD-R, that lacks L-lactate dehydrogenase activity was studied in anaerobic single-stage continuous culture using a defined minimal medium for its capacity to produce ethanol from sucrose at 70 "C. Cultures were stable at neutral pH, dilu ...
Pathways of NeurSospora crassa and Saccharomyces cerevisiaet
Pathways of NeurSospora crassa and Saccharomyces cerevisiaet

... maintains the level of bound acetyl groups as cells grow and divide, and it counters deacetylation. The synthase reaction is feedback inhibited by arginine, as is the next step in the pathway, acetylglutamate kinase. This assures control of ornithine synthesis if arginine becomes plentiful, regardle ...
Epidermal Lipids and Formation of the Barrier of the Skin
Epidermal Lipids and Formation of the Barrier of the Skin

... fat, and environmental hydrocarbons. When the known contaminants are factored out, it is apparent that the main stratum corneum lipids are ceramides, cholesterol, and free fatty acids in the ratio of 50:27:12 by weight. When the average molecular weights are taken into consideration, these major com ...
Acetyl CoA - WordPress.com
Acetyl CoA - WordPress.com

... regenerated when NADH ultimately transfers its electrons to O2 through the electron transport chain in mitochondria In the overall reaction, the carboxyl group of pyruvate is lost as CO2 while the remaining two carbons form the acetyl moiety of acetyl-CoA generation of a reduced electron carrier (NA ...
Agoraphobia - Orthomolecular.org
Agoraphobia - Orthomolecular.org

... ORTHOMOLECULAR PSYCHIATRY, VOLUME 11, NUMBER 4, 1982 Pp. 243-259 ...
b156 - IPB Repository - Bogor Agricultural University
b156 - IPB Repository - Bogor Agricultural University

... Shoyu is a traditional Japanese soy sauce that is made from a mixture of soybeans and wheat using a well-established two-step fermentation process, which involves koji-mold fermentation to yield koji and brine fermentation to yield moromi. The Japanese people recognize five distinct types of shoyu, ...
Polyclonal Anti-Collagen Type I
Polyclonal Anti-Collagen Type I

... Granulocyte-macrophage colony-stimulating factor (GM-CSF) is also symbolized CSF2. Human GM-CSF is a glycoprotein that is essential for the in vitro proliferation and differentiation of precursor cells into mature granulocytes and macrophages. The human cDNA clones contain a single open-reading fram ...
Growth, digestive and absorptive capacity and
Growth, digestive and absorptive capacity and

... threonine on digestive and absorptive capacity of herbivorous grass carp (Ctenopharyngodonidella). The function of fish digestive organ is correlated with its development [9]. Threonine has been shown to improve intestinal folds height in juvenile Jian carp [5], as well as anterior intestinal villus ...
Recent advances in biosynthesis of fatty acids derived products in
Recent advances in biosynthesis of fatty acids derived products in

... precursor metabolites and the FAS complex are highly regulated at multiple levels, current engineering efforts targeted at both structural and regulatory genes will be discussed. ...
Human Physiology An Integrated Approach 6/E
Human Physiology An Integrated Approach 6/E

... Activation energy is the initial input of energy required to bring reactants into a position that allows them to react with one another. This “push” needed to start the reaction is shown in Figure 4.3a as the little hill up which the ball must be pushed before it can roll by itself down the slope. A ...
Nonribosomal peptide synthesis in Aspergillus
Nonribosomal peptide synthesis in Aspergillus

... These enzymes are often encoded within gene clusters. Multiple NRP synthetase ORFs have also been identified in fungi (14 in Aspergillus fumigatus). LeaA, a methyltransferase, is involved in secondary metabolite gene cluster regulation in Aspergillus spp. The NRP synthetases GliP and FtmA respective ...
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Amino acid synthesis

Amino acid synthesis is the set of biochemical processes (metabolic pathways) by which the various amino acids are produced from other compounds. The substrates for these processes are various compounds in the organism's diet or growth media. Not all organisms are able to synthesise all amino acids. Humans are excellent example of this, since humans can only synthesise 11 of the 20 standard amino acids (aka non-essential amino acid), and in time of accelerated growth, arginine, can be considered an essential amino acid.A fundamental problem for biological systems is to obtain nitrogen in an easily usable form. This problem is solved by certain microorganisms capable of reducing the inert N≡N molecule (nitrogen gas) to two molecules of ammonia in one of the most remarkable reactions in biochemistry. Ammonia is the source of nitrogen for all the amino acids. The carbon backbones come from the glycolytic pathway, the pentose phosphate pathway, or the citric acid cycle.In amino acid production, one encounters an important problem in biosynthesis, namely stereochemical control. Because all amino acids except glycine are chiral, biosynthetic pathways must generate the correct isomer with high fidelity. In each of the 19 pathways for the generation of chiral amino acids, the stereochemistry at the α-carbon atom is established by a transamination reaction that involves pyridoxal phosphate. Almost all the transaminases that catalyze these reactions descend from a common ancestor, illustrating once again that effective solutions to biochemical problems are retained throughout evolution.Biosynthetic pathways are often highly regulated such that building-blocks are synthesized only when supplies are low. Very often, a high concentration of the final product of a pathway inhibits the activity of enzymes that function early in the pathway. Often present are allosteric enzymes capable of sensing and responding to concentrations of regulatory species. These enzymes are similar in functional properties to aspartate transcarbamoylase and its regulators. Feedback and allosteric mechanisms ensure that all twenty amino acids are maintained in sufficient amounts for protein synthesis and other processes.
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