Organic Chemistry I (CHEM 2010 and 2012)
... Course Description: The course involves a systematic study of various classes of organic compounds including their physical and chemical properties, nomenclature, stereochemistry, synthesis and reactions. The course also introduces Mass Spectroscopy, Infra-Red Spectroscopy, Nuclear Magnetic Resonanc ...
... Course Description: The course involves a systematic study of various classes of organic compounds including their physical and chemical properties, nomenclature, stereochemistry, synthesis and reactions. The course also introduces Mass Spectroscopy, Infra-Red Spectroscopy, Nuclear Magnetic Resonanc ...
Chemistry 112A Second Midterm Review Sheet Summary of
... Allowing fluorine (lowest priority) to point away from the viewer the rotation is clockwise hence the R-assignment. In the assignment of L-serine highest priority is given to the nitrogen atom (Z = 7) in the amino group (NH2). Both the methylalcohol group (CH2OH ) and the carboxylic acid group (COOH ...
... Allowing fluorine (lowest priority) to point away from the viewer the rotation is clockwise hence the R-assignment. In the assignment of L-serine highest priority is given to the nitrogen atom (Z = 7) in the amino group (NH2). Both the methylalcohol group (CH2OH ) and the carboxylic acid group (COOH ...
General properties of urea : It is water
... General properties of urea : It is water-soluble crystalline compound acting only as a weak base giving sparingly soluble salts with HNO3 and ethanedioic acid (COOH)2 . In its chemical properties, urea gives the typical reaction expected from an amide (twice over) Its properties are essentially thos ...
... General properties of urea : It is water-soluble crystalline compound acting only as a weak base giving sparingly soluble salts with HNO3 and ethanedioic acid (COOH)2 . In its chemical properties, urea gives the typical reaction expected from an amide (twice over) Its properties are essentially thos ...
Elimination Reactions
... Draw a mechanism and energy diagram for elimination of an alcohol under acidic conditions Explain how additions of water to an alkene and elimination of an alcohol are opposite mechanisms Describe how to shift equilibrium in favor of elimination or addition Predict the major product accordin ...
... Draw a mechanism and energy diagram for elimination of an alcohol under acidic conditions Explain how additions of water to an alkene and elimination of an alcohol are opposite mechanisms Describe how to shift equilibrium in favor of elimination or addition Predict the major product accordin ...
The Baylis–Hillman reaction is an organic reaction of an aldehyde
... The Henry reaction begins with the deprotonation of the nitroalkane on the α-carbon position forming a resonance stabilized anion. This is followed by alkylation of the nitroalkane with the carbonyl containing substrate to form a diastereomeric β-nitro alkoxide. The protonation of the alkoxide by th ...
... The Henry reaction begins with the deprotonation of the nitroalkane on the α-carbon position forming a resonance stabilized anion. This is followed by alkylation of the nitroalkane with the carbonyl containing substrate to form a diastereomeric β-nitro alkoxide. The protonation of the alkoxide by th ...
Ch 7: Reactions
... • 4) Does your reaction have any molecules that contain only one element? If yes, then it's a single displacement reaction • 5) Does your reaction have water as one of the products? If yes, then it's an acid-base reaction • 6) If you haven't answered "yes" to any of the questions above, then you've ...
... • 4) Does your reaction have any molecules that contain only one element? If yes, then it's a single displacement reaction • 5) Does your reaction have water as one of the products? If yes, then it's an acid-base reaction • 6) If you haven't answered "yes" to any of the questions above, then you've ...
Chemistry of Nitrogen-containing Organic
... 2. Draw a reaction mechanism for an acyl chloride with 3 carbon atoms reacting with ethylamine. 3. What is this type of reaction called? 4. What type of organic compound is the product? ...
... 2. Draw a reaction mechanism for an acyl chloride with 3 carbon atoms reacting with ethylamine. 3. What is this type of reaction called? 4. What type of organic compound is the product? ...
Topic 16 Test - A
... How many structural isomers, which are aldehydes, have the molecular formula C5H10O? A ...
... How many structural isomers, which are aldehydes, have the molecular formula C5H10O? A ...
Synthesis of (−)-Epibatidine - David A. Evans
... Fortunately, it was found that 9 could be converted to methyl ester 10 using Sm(OTf)3 in refluxing MeOH. The success of this reaction may be due to activation of the imide by chelation of the Sm(III) cation with both carbonyl oxygens.13 To facilitate the desired C1-N bond scission, amide 10 was conv ...
... Fortunately, it was found that 9 could be converted to methyl ester 10 using Sm(OTf)3 in refluxing MeOH. The success of this reaction may be due to activation of the imide by chelation of the Sm(III) cation with both carbonyl oxygens.13 To facilitate the desired C1-N bond scission, amide 10 was conv ...
CHAPTER 13 Approaches to the Asymmetric Synthesis of Unusual
... 3. Dlastereoselectlve Strecker and Ugl reactions with optically active ammes; and 4. Diastereoselective hydrogenation of a, P-dehydroammo acid derivatives. ...
... 3. Dlastereoselectlve Strecker and Ugl reactions with optically active ammes; and 4. Diastereoselective hydrogenation of a, P-dehydroammo acid derivatives. ...
week 4_carbohydrates
... • in aqueous solution, monosaccharides with five or more carbon atoms in the backbone occur predominantly as cyclic (ring) structures in which the carbonyl group has formed a covalent bond with the oxygen of a hydroxyl group along the chain. • Sir Norman Haworth showed that the linear form of glucos ...
... • in aqueous solution, monosaccharides with five or more carbon atoms in the backbone occur predominantly as cyclic (ring) structures in which the carbonyl group has formed a covalent bond with the oxygen of a hydroxyl group along the chain. • Sir Norman Haworth showed that the linear form of glucos ...
CYSTEINE
... Has thiol group containing sulfur Molecular formula is C3H7NO2S Cysteine along with glycine and glutamic acid is found in all human tissues Can form into Cystine when exposed to air due to oxidation Stabilizes extracellular protein ...
... Has thiol group containing sulfur Molecular formula is C3H7NO2S Cysteine along with glycine and glutamic acid is found in all human tissues Can form into Cystine when exposed to air due to oxidation Stabilizes extracellular protein ...
SYNOPSIS
... The acid-catalyzed reaction of electron-rich heterocyclic compounds with pdimethylamino benzaldehyde is known as Ehrlich test for -electron excessive heterocycles such as pyroles and indoles. The analogous reaction of indoles with other aromatic or aliphatic aldehyde and ketones produces azafulveni ...
... The acid-catalyzed reaction of electron-rich heterocyclic compounds with pdimethylamino benzaldehyde is known as Ehrlich test for -electron excessive heterocycles such as pyroles and indoles. The analogous reaction of indoles with other aromatic or aliphatic aldehyde and ketones produces azafulveni ...
Alcohol oxidation
... The mechanism of the Jacobsen–Katsuki epoxidation is not fully understood, but most likely a manganese(V)-species is the reactive intermediate which is formed upon the oxidation of the Mn(III)-salen complex. The most accepted mechanism is the concerted pathway mechanism. After the formation of the M ...
... The mechanism of the Jacobsen–Katsuki epoxidation is not fully understood, but most likely a manganese(V)-species is the reactive intermediate which is formed upon the oxidation of the Mn(III)-salen complex. The most accepted mechanism is the concerted pathway mechanism. After the formation of the M ...
Isolating High Value Aromatics from Lignin Stockpiles
... industry and a majority is inefficiently burned as fuel.2 However, lignin contains many aromatics and has the potential to produce high value chemicals through arylheteroatom bond cleavage. These aryl-heteroatom bonds are very stable and require large amount of energy to cleave so catalysts have bee ...
... industry and a majority is inefficiently burned as fuel.2 However, lignin contains many aromatics and has the potential to produce high value chemicals through arylheteroatom bond cleavage. These aryl-heteroatom bonds are very stable and require large amount of energy to cleave so catalysts have bee ...
Worked_Examples
... attractions or hydrogen bonds, pentane has the lowest boiling point of the three compounds. With a polar carbonyl group, butanone molecules form dipole–dipole attractions, but no hydrogen bonds. Butanone has a higher boiling point than pentane. Because molecules of 2-butanol can form hydrogen bonds ...
... attractions or hydrogen bonds, pentane has the lowest boiling point of the three compounds. With a polar carbonyl group, butanone molecules form dipole–dipole attractions, but no hydrogen bonds. Butanone has a higher boiling point than pentane. Because molecules of 2-butanol can form hydrogen bonds ...
CHEM 212B, Organic Chemistry - City College of San Francisco
... A continuation of CHEM 212A. The second semester of a one-year course in organic chemistry for students who major in chemistry, biochemistry, and other chemistry-intensive sciences. IV. MAJOR LEARNING OUTCOMES Upon completion of this course a student will be able to: A. Name and draw the structures ...
... A continuation of CHEM 212A. The second semester of a one-year course in organic chemistry for students who major in chemistry, biochemistry, and other chemistry-intensive sciences. IV. MAJOR LEARNING OUTCOMES Upon completion of this course a student will be able to: A. Name and draw the structures ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 PART-A
... ‘Aryldiazonium salt involves both in electrophilic and nucleophilic substitutions’. Justify. What is first order asymmetric transformation? Give an example. How do inductive and field effects affect the second substitution in aromatic systems? In 4-t-butylcyclohexanecarboxylic acid, trans form is mo ...
... ‘Aryldiazonium salt involves both in electrophilic and nucleophilic substitutions’. Justify. What is first order asymmetric transformation? Give an example. How do inductive and field effects affect the second substitution in aromatic systems? In 4-t-butylcyclohexanecarboxylic acid, trans form is mo ...
Organic Chemistry Chem 121: Topics
... The mirror image of an enantiomer will rotate the plane of polarized light by the same amount in the opposite direction. Eg (+) d-carvone +62o (caraway) and (-) l-carvone -62o (spearmint)…. What about a 50:50 (racemic) mixture? ...
... The mirror image of an enantiomer will rotate the plane of polarized light by the same amount in the opposite direction. Eg (+) d-carvone +62o (caraway) and (-) l-carvone -62o (spearmint)…. What about a 50:50 (racemic) mixture? ...
supplemenatary material - Royal Society of Chemistry
... oxidized with KMnO4/ MgSO4 in acetone to convert the aldehydes in the corresponding acids, which where then analyzed by GC with a chiral column to determine the enantiomeric excess. Some samples were also reduced to alcohols with a suspension of LiAlH4 in THF, and the resulting alcohols were also an ...
... oxidized with KMnO4/ MgSO4 in acetone to convert the aldehydes in the corresponding acids, which where then analyzed by GC with a chiral column to determine the enantiomeric excess. Some samples were also reduced to alcohols with a suspension of LiAlH4 in THF, and the resulting alcohols were also an ...
Enantioselective synthesis
Enantioselective synthesis, also called chiral synthesis or asymmetric synthesis, is defined by IUPAC as: a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereoisomeric) products in unequal amounts.Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer.Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity.