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NCEA Level 2 Chemistry (91165) 2012 Assessment Schedule
NCEA Level 2 Chemistry (91165) 2012 Assessment Schedule

... links between the structure, functional groups and the chemical properties of selected organic compounds. This requires the consistent use of chemistry vocabulary, symbols and conventions. ...
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... a [2+2] photocycloaddition. A challenging part of this approach is to obtain enantiomerically pure β-hydroxy-ketones (17, figure 1), which are required for the synthesis of the photo substrate (1). Chiral acetals are used to obtain β-hydroxy-ketones via diastereoselective addition of Grignard reagen ...
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Enantioselective synthesis



Enantioselective synthesis, also called chiral synthesis or asymmetric synthesis, is defined by IUPAC as: a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereoisomeric) products in unequal amounts.Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer.Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity.
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