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Inhibition of RNA Synthesis by Anthracycline Analogs
Inhibition of RNA Synthesis by Anthracycline Analogs

... of anthracyclines in the treatment of leukemias and other forms of cancer. The biological and pharmacological activities of these drugs appear to be, at least in part, due to their ability to interact with DNA. ...
Ch6_seq_alignment
Ch6_seq_alignment

... • Based on percent sequence identity • Based on conservation ...
NO sensing by FNR: regulation of the Escherichia coli NO
NO sensing by FNR: regulation of the Escherichia coli NO

... A putative FNR box, TTGAG----ATCAA, with a strong resemblance to the consensus FNR-binding sequence is centred at position +5.5 in the Phmp region. To determine whether the putative FNR box is actually recognized by FNR, mutations were made in which the central G (underlined above) was mutated to A, ...
Suberin biosynthesis in O. sativa: characterisation of a cytochrome
Suberin biosynthesis in O. sativa: characterisation of a cytochrome

... 1.1.1 Aromatic and aliphatic polymers in vascular plants The distribution of nutrients and metabolites depends on concentration gradients and diffusion, which restricts the size of lower plants. The appearance of bigger multicellular organisms required the development of vascular tissues, and along ...
CSE 181 Project guidelines - UCSD CSE
CSE 181 Project guidelines - UCSD CSE

... • Based on percent sequence identity • Based on conservation ...
SOLUTIONS TO NEET 2017 - (7-5-2017) - Code P
SOLUTIONS TO NEET 2017 - (7-5-2017) - Code P

... (1) The ascending limb of loop of Henle is impermeable to water. (2) The descending limb of loop of Henle is impermeable to water. (3) The ascending limb of loop of Henle is permeable to water. (4) The descending limb of loop of Henle is permeable to electrolytes. XI NCERT Page 294 ...
Role of adiponectin in the regulation of carbohydrate and lipid
Role of adiponectin in the regulation of carbohydrate and lipid

Differential Enzyme Targeting As an Evolutionary Adaptation to
Differential Enzyme Targeting As an Evolutionary Adaptation to

... RAGE (Mizobuchi and Frohman 1993) (with the exception of the domestic cat, the cDNA of which had previously been cloned [Lumb, Purdue, and Danpure 1994]). The amplified region included all the sequence from exon 1 and most or all of the 59 UTR (see fig. 3A). Analysis of the sequences revealed the pr ...
Life in the slow lane: molecular mechanisms of estivation
Life in the slow lane: molecular mechanisms of estivation

... quickly dig out from underground, males immediately set up breeding choruses, and mating and egg-laying occur within the first night in rainwater ponds. Adults then become ravenous eaters and over the next few days replenish the fuel reserves needed to sustain them for many more months underground. ...
Regulation of Ketone Body Metabolism and the Role of PPAR
Regulation of Ketone Body Metabolism and the Role of PPAR

... Activated Receptors (PPARs) are important regulators of cellular responses to variable nutrient supply during both fed and fasted states. Acting as transcription factors, and directly modulated by fatty acids and their derivatives, PPARs induce transcription of the proper set of genes, encoding prot ...
Proteome analysis of tobacco BY-2 cell culture - ETH E
Proteome analysis of tobacco BY-2 cell culture - ETH E

... distinguish plant cells from those of other eukaryotes. The origin and evolution of plastids has been an important subject in biological sciences. Plastids represent the endosymbiotic remnants of a free-living cyanobacterial progenitor, which lost the vast majority of its ancestral cyanobacterial ge ...
Insights into interactions between poly(ethylene glycol) and proteins
Insights into interactions between poly(ethylene glycol) and proteins

View/Open
View/Open

... gross structure and number of chromosomes in cells. In this chapter, we investigate how these alterations happen and what their consequences are to the organism. ...
Molecular mechanics of the interactions of spermine with DNA: DNA
Molecular mechanics of the interactions of spermine with DNA: DNA

... implies stabilization of double-stranded over single-stranded forms. It was found recently that polyamines also stabilize both the left-handed Z conformation (10,11) and the right-handed A conformation (12) of nucleic acids. Stabilization of specific DNA ...
A motif and amino acid bias bioinformatics
A motif and amino acid bias bioinformatics

... (Pietrosemoli et al., 2013; Sun et al., 2013). As plants are sessile, IDPs related to environmental stress ...
Phosphorylation of the F1Fo ATP Synthase Я Subunit
Phosphorylation of the F1Fo ATP Synthase Я Subunit

... subunit),17 but there is currently no evidence that phosphorylation of ATP␤ regulates any aspect of the complex. Regulation of this complex could come at a variety of points: transcription, translation, import, assembly, or direct functional regulation. The F1Fo ATP synthase is a well-conserved enzy ...
IN VIVO ENOL CASTOR OIL SEEDS AT THREONINE-4 AND SERINE-451
IN VIVO ENOL CASTOR OIL SEEDS AT THREONINE-4 AND SERINE-451

... everyday and a lot of nights with laughs. I would like to specially thank Brendan O’Leary for all his guidance and support in and out of the lab, the journey would not have been as enjoyable without such a great mentor in the lab. Thank you to the Snedden lab, Kyle Bender and David Maj, for always p ...
Advanced Stochastic Protein Sequence Analysis
Advanced Stochastic Protein Sequence Analysis

... initially found evidence for approximately 30 000 transcripts and recently only 20 000 to 25 000 genes were supposed [IHG04]. Surprisingly, the sets of genes found by both groups interleave only to a percentage of approximately 21% [Hog01]. It is believed that only about 60 percent of the proteins e ...
Different susceptibility of two animal species infected with isogenic
Different susceptibility of two animal species infected with isogenic

... 105 c.f.u. of M. bovis in 200 ml. The organisms were inoculated through a 2 mm diameter vinyl cannula per os into the trachea of anaesthetized animals as described previously (Pfeffer et al., 1994) and killed after 6 weeks. The assessment of virulence in early work was based on the presence of visib ...
H. Heldt
H. Heldt

... This textbook is written for students and is the product of more than three decades of my teaching experience. It intends to give a broad but concise overview of the various aspects of plant biochemistry, including molecular biology. I have attached importance to an easily understood description of ...
Lab Manual - GRCC Instructional Home Page
Lab Manual - GRCC Instructional Home Page

Was photosynthetic RuBisCO recruited by
Was photosynthetic RuBisCO recruited by

... per second, even when substrate is saturating [2,18]. As a consequence, the photosynthetic CO2 assimilation rate is limited by RuBisCO in plants [20,36]. To overcome these disadvantages, plants are obliged to invest a large amount of nitrogen to synthesize RuBisCO, which accounts for about 50% of al ...
Branching Processes in Biology - Rice Statistics
Branching Processes in Biology - Rice Statistics

... • Cell is resistant if it carries at least one double minute chromosome with the DHFR gene. • Otherwise it is called sensitive. • Population of cells resistant to MTX, previously cultured for N generations in medium containing MTX, initially consists only of cells with at least one DHFR gene copy, i ...
Plant Biochemistry
Plant Biochemistry

... This textbook is written for students and is the product of more than three decades of my teaching experience. It intends to give a broad but concise overview of the various aspects of plant biochemistry, including molecular biology. I have attached importance to an easily understood description of ...
Autosomal and X-chromosome imprinting
Autosomal and X-chromosome imprinting

... proximal regions of chromosomes, they cannot be used effectively to provide information on possible genetic background effects. It is worth noting, however, that the proximal chromosome 6 lethality was observed in two separate studies with two different Robertsonian translocations (one of which is o ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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