The Genetic, Developmental, and Molecular Bases
... variety may contain many locules and weigh up to 1 kg, a nearly 1000-fold increase in weight (Figure 1A). A similar situation exists for most other domesticated fruit species (Smartt and Simmonds, 1995). In addition to increases in fruit size, the domestication of fruit-bearing species often has res ...
... variety may contain many locules and weigh up to 1 kg, a nearly 1000-fold increase in weight (Figure 1A). A similar situation exists for most other domesticated fruit species (Smartt and Simmonds, 1995). In addition to increases in fruit size, the domestication of fruit-bearing species often has res ...
The Heart as an Endocrine Gland
... purification attempts established the polypeptide nature of ANF and the amino acid composition of short (C-terminal) peptides. 3 In June 1983 we isolated and sequenced, among others, a 33-amino acid peptide that is part of a larger molecule containing at least 106 amino acids.*~6 After its sequencin ...
... purification attempts established the polypeptide nature of ANF and the amino acid composition of short (C-terminal) peptides. 3 In June 1983 we isolated and sequenced, among others, a 33-amino acid peptide that is part of a larger molecule containing at least 106 amino acids.*~6 After its sequencin ...
Defining the Schistosoma haematobium kinome enables the
... Figs 1–11), consistent with their classification using an approach based on hidden Markov models (HMMs). Seven kinase sequences were excluded from phylogenetic analysis, because the catalytic domain of one or both representatives of the orthologous pair did not match the trematode-specific HMM. Six ...
... Figs 1–11), consistent with their classification using an approach based on hidden Markov models (HMMs). Seven kinase sequences were excluded from phylogenetic analysis, because the catalytic domain of one or both representatives of the orthologous pair did not match the trematode-specific HMM. Six ...
tubulin - Journal of Cell Science
... Positions of insertions and deletions A dramatic sequence deviation concerning a highly conserved tubulin motif occurs for all four known δ-tubulins in loop T7, further emphasizing divergence of this tubulin with respect to the rest. The consensus sequence GxxNxD is changed to YxxN-P. We expect this ...
... Positions of insertions and deletions A dramatic sequence deviation concerning a highly conserved tubulin motif occurs for all four known δ-tubulins in loop T7, further emphasizing divergence of this tubulin with respect to the rest. The consensus sequence GxxNxD is changed to YxxN-P. We expect this ...
The Deletion Stocks of Common Wheat
... Chromosomal breaks occurred in the progeny of a common wheat (Tritlcum aestlvum L. em Thell; 2n = 6x = 42, genome formula AABBDD) cultivar Chinese Spring with a monosomic addition of an alien chromosome from Aegllops cyllndrlca Host (2n = 4x = 28, CCDD) or A. trlunclalls L. (2n = 4x = 28, UUCC) or a ...
... Chromosomal breaks occurred in the progeny of a common wheat (Tritlcum aestlvum L. em Thell; 2n = 6x = 42, genome formula AABBDD) cultivar Chinese Spring with a monosomic addition of an alien chromosome from Aegllops cyllndrlca Host (2n = 4x = 28, CCDD) or A. trlunclalls L. (2n = 4x = 28, UUCC) or a ...
PATHOPHYSIOLOGY OF RED BLOOD CELLS Zsófia Mezei, MD
... Large ( MCV) and strong staining (MCH, MCHC) Cells are found in circulation and bone marrow as well ...
... Large ( MCV) and strong staining (MCH, MCHC) Cells are found in circulation and bone marrow as well ...
Cycloguanil and Its Parent Compound Proguanil Demonstrate
... from DHFR. We propose a strategy of combination chemotherapy incorporating the use of multiple parasite-specific inhibitors that act at the same molecular target and thereby maintain, in combination, their effectiveness against alternative forms of resistance that arise from different sets of point ...
... from DHFR. We propose a strategy of combination chemotherapy incorporating the use of multiple parasite-specific inhibitors that act at the same molecular target and thereby maintain, in combination, their effectiveness against alternative forms of resistance that arise from different sets of point ...
View PDF - OSU Biochemistry and Molecular Biology
... Hox function, but also to elucidate the mechanisms of Hox target gene selection and regulation. In this context, chromatin immunoprecipitation (ChIP) was developed, which has become one of the most powerful tools for the study of protein–DNA interactions in vivo. Before genomic arrays or massively p ...
... Hox function, but also to elucidate the mechanisms of Hox target gene selection and regulation. In this context, chromatin immunoprecipitation (ChIP) was developed, which has become one of the most powerful tools for the study of protein–DNA interactions in vivo. Before genomic arrays or massively p ...
Pyridoxine Pyridoxal Pyridoxamine
... Large doses of vitamin B6 (over 2,000 mg) can cause nerve damage. The tolerable upper intake level (UL) for vitamin B6 from dietary sources and supplements combined is 100 mg per day. Symptoms of vitamin B6 toxicity include: muscle incoordination, incoordination, numbness of the hands and feet, impa ...
... Large doses of vitamin B6 (over 2,000 mg) can cause nerve damage. The tolerable upper intake level (UL) for vitamin B6 from dietary sources and supplements combined is 100 mg per day. Symptoms of vitamin B6 toxicity include: muscle incoordination, incoordination, numbness of the hands and feet, impa ...
LAP5 and LAP6 encode anther-specific proteins with similarity to
... development, still relatively little is known about the genetic network that governs the formation of this structure and the pathways that lead to its biosynthesis are far from being understood. In recent years, the importance of fatty acid-derived components in sporopollenin composition has been re ...
... development, still relatively little is known about the genetic network that governs the formation of this structure and the pathways that lead to its biosynthesis are far from being understood. In recent years, the importance of fatty acid-derived components in sporopollenin composition has been re ...
SPATULA, a bHLH carpel development gene
... Recessive mutations in the SPATULA (SPT) gene specifically disrupt development of the pollen tract tissues including the transmitting tract, style and stigma (Alvarez and Smyth, 1999). These disruptions affect the presumed precursors of these tissues as early as stage 7 when the gynoecial cylinder s ...
... Recessive mutations in the SPATULA (SPT) gene specifically disrupt development of the pollen tract tissues including the transmitting tract, style and stigma (Alvarez and Smyth, 1999). These disruptions affect the presumed precursors of these tissues as early as stage 7 when the gynoecial cylinder s ...
Virp1 Is a Host Protein with a Major Role in Potato - IMBB
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
Genetic and molecular regulation of fruit and plant domestication
... cultivated tomatoes, and appears to have been present in the wild germplasm prior to the domestication of this crop (Nesbitt and Tanksley, 2002). The function of the protein is proposed to be a regulator of cell division since larger fruit size is associated with more cells per unit tissue (Frary et ...
... cultivated tomatoes, and appears to have been present in the wild germplasm prior to the domestication of this crop (Nesbitt and Tanksley, 2002). The function of the protein is proposed to be a regulator of cell division since larger fruit size is associated with more cells per unit tissue (Frary et ...
A Truncated Laminin Chain Homologous to the B2 Chain: Structure
... In vitro de- and renaturation studies with EHS laminin have shown that the assembly of this laminin is a specific process and only molecules with one Ae chain, one Ble chain, and one B2e chain are formed (35, 36). The carboxyl-terminal parts of laminin chains assemble into a coiled-coil structure. T ...
... In vitro de- and renaturation studies with EHS laminin have shown that the assembly of this laminin is a specific process and only molecules with one Ae chain, one Ble chain, and one B2e chain are formed (35, 36). The carboxyl-terminal parts of laminin chains assemble into a coiled-coil structure. T ...
Viva Voce : Orals in Biochemistry
... Saturated fatty acids: All the naturally occuring fatty acids have even number of ‘c’ atoms. Most predominant fatty acids which occur in nature are: (i) Palmitic acid ...
... Saturated fatty acids: All the naturally occuring fatty acids have even number of ‘c’ atoms. Most predominant fatty acids which occur in nature are: (i) Palmitic acid ...
Control of DNA excision efficiency in Paramecium
... micronuclei undergo meiosis, whereas the macronuclei degenerate. The fusion of two gametic nuclei produces a zygotic nucleus. This nucleus divides twice and the daughter nuclei then differentiate into a micronucleus or a macronucleus. In the second case, the whole genome is processed through chromos ...
... micronuclei undergo meiosis, whereas the macronuclei degenerate. The fusion of two gametic nuclei produces a zygotic nucleus. This nucleus divides twice and the daughter nuclei then differentiate into a micronucleus or a macronucleus. In the second case, the whole genome is processed through chromos ...
hematology case study: a hypochromic, microcytic anemia
... have been identified, giving geneticists much fodder for investigation. BETA THALASSEMIA There are 2 genes for production of beta chains, one on each chromosome 11. The genetics of decreased production of beta chains is more complex than that found in alpha thalassemia. thalassemias are heterogeneo ...
... have been identified, giving geneticists much fodder for investigation. BETA THALASSEMIA There are 2 genes for production of beta chains, one on each chromosome 11. The genetics of decreased production of beta chains is more complex than that found in alpha thalassemia. thalassemias are heterogeneo ...
Fatty Acid Synthesis in Protozoan Parasites: Unusual Pathways and
... From a functional perspective, however, grouping these evolutionarily diverse organisms together can be informative. All share similar environments, being intimately associated with their human hosts. The access these parasites have to the products of host metabolism has led to striking similarities ...
... From a functional perspective, however, grouping these evolutionarily diverse organisms together can be informative. All share similar environments, being intimately associated with their human hosts. The access these parasites have to the products of host metabolism has led to striking similarities ...
Analysis of the Molecular Basis of Flowering Time Variation in
... (Karlsson et al., 1993; Nordborg and Bergelson, 1999), but the F1 plants from the crosses to Col flowered even later, suggesting that Kondara and Kz-9 FRI alleles are fully functional and confer very late flowering in the presence of the strong Col FLC allele. Given the identical amino acid sequence ...
... (Karlsson et al., 1993; Nordborg and Bergelson, 1999), but the F1 plants from the crosses to Col flowered even later, suggesting that Kondara and Kz-9 FRI alleles are fully functional and confer very late flowering in the presence of the strong Col FLC allele. Given the identical amino acid sequence ...
Quantitative analysis of SMN1 and SMN2 genes based on DHPLC
... These two SMN genes are highly homologous and differ in only two nucleotides in the coding region. These nucleotide differences, located in exons 7 and 8, allow the SMN1 gene to be distinguished from the SMN2 gene [Lefebvre et al., 1995]. It has been reported that approximately 94% of SMA patients w ...
... These two SMN genes are highly homologous and differ in only two nucleotides in the coding region. These nucleotide differences, located in exons 7 and 8, allow the SMN1 gene to be distinguished from the SMN2 gene [Lefebvre et al., 1995]. It has been reported that approximately 94% of SMA patients w ...
9 The AMP-activated protein kinase: more than an energy sensor
... differ. When phosphorylated, the ␣2-subunit translocates to the nucleus during hypoxia or in contracting muscle, whereas the ␣1-subunit remains cytoplasmic. In specialized tissues such as the carotid body glomus cells, the ␣1-subunit, which appears as the effector of hypoxic chemotransduction, is ta ...
... differ. When phosphorylated, the ␣2-subunit translocates to the nucleus during hypoxia or in contracting muscle, whereas the ␣1-subunit remains cytoplasmic. In specialized tissues such as the carotid body glomus cells, the ␣1-subunit, which appears as the effector of hypoxic chemotransduction, is ta ...
Malonate decarboxylase of Pseudomonas putida is composed of
... with [2-14 C]malonyl-CoA, the N subunit became labeled by 14 C radioactivity (Fig. 3, lane 2). Furthermore, the labeled [2-14 C]malonyl-residue of N subunit was completely released by incubating with an excess amount of cold malonate (Fig. 3, lane 3). On the other hand, the N subunit of catalyticall ...
... with [2-14 C]malonyl-CoA, the N subunit became labeled by 14 C radioactivity (Fig. 3, lane 2). Furthermore, the labeled [2-14 C]malonyl-residue of N subunit was completely released by incubating with an excess amount of cold malonate (Fig. 3, lane 3). On the other hand, the N subunit of catalyticall ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.