
Additional Glossary and Concepts List for Vertebrate Genetics
... lowering the expression of a locus by shRNA is usually referred to as knock-down and not knock-out. Mono-allelic expression (allelic exclusion) Cellular expression of only one of the two alleles encoded in the genome for the particular gene. The allele that is expressed can be randomly chosen (eg, o ...
... lowering the expression of a locus by shRNA is usually referred to as knock-down and not knock-out. Mono-allelic expression (allelic exclusion) Cellular expression of only one of the two alleles encoded in the genome for the particular gene. The allele that is expressed can be randomly chosen (eg, o ...
Chapter Outline
... • Some recessive alleles, blood type O, are the most common • Some dominant alleles, polydactyly and blood type AB, are rare ...
... • Some recessive alleles, blood type O, are the most common • Some dominant alleles, polydactyly and blood type AB, are rare ...
Organic Macromolecules
... Read Chapter 3 in your book and fill out this graphic organizer. You will use this when you do your Macromolecule Flapbook. Organic Molecule Simple Carbohydrate ...
... Read Chapter 3 in your book and fill out this graphic organizer. You will use this when you do your Macromolecule Flapbook. Organic Molecule Simple Carbohydrate ...
Study Guide for Understanding the Concept of Protein Synthesis
... DNA contains the genetic material and serves as the blueprint for protein synthesis. The doublestranded DNA "unzips" -- leaving the second strand as a pattern (template) of instruction for RNA. [Think of a "zipper". Zipped, the zipper has the appearance of one (1) strand. When unzipped, it is obviou ...
... DNA contains the genetic material and serves as the blueprint for protein synthesis. The doublestranded DNA "unzips" -- leaving the second strand as a pattern (template) of instruction for RNA. [Think of a "zipper". Zipped, the zipper has the appearance of one (1) strand. When unzipped, it is obviou ...
Untangling the Spirals of Metabolic Disease: Primary Diagnoses and Secondary Effects:
... Reduced fat diet (maximum of 25% of all calories from fat Normal growth and development, no residual neurological deficit Now has muscle cramps with exercise (baseball). Her older sister (then 7 years of age) is diagnosed on the basis of DNA analysis, although never symptomatic Two subsequent uncomp ...
... Reduced fat diet (maximum of 25% of all calories from fat Normal growth and development, no residual neurological deficit Now has muscle cramps with exercise (baseball). Her older sister (then 7 years of age) is diagnosed on the basis of DNA analysis, although never symptomatic Two subsequent uncomp ...
Proteins
... The shaping of the secondary structure with many twists and folds into a 3D shape. There may be several areas of coiling and pleating with straight chain amino acids in between. Four types of bonds hold these together Disulphide bonds Ionic Bonds Hydrogen bonds Hydrophobic and hydrophilic interactio ...
... The shaping of the secondary structure with many twists and folds into a 3D shape. There may be several areas of coiling and pleating with straight chain amino acids in between. Four types of bonds hold these together Disulphide bonds Ionic Bonds Hydrogen bonds Hydrophobic and hydrophilic interactio ...
Document
... Addition/deletion of DNA Point mutation Keeping track of gene variants – Concepts of ortholog / paralog ...
... Addition/deletion of DNA Point mutation Keeping track of gene variants – Concepts of ortholog / paralog ...
No Slide Title
... appropriate DNA sequences. Proteins interact synergistically to elevate transcription rate. In b-interferon gene transcription, TFs recruit a coactivator (CBP) which is needed for transcription to occur normally. Formation of the enhanceosome and activation of RNA polymerase by coactivator are neces ...
... appropriate DNA sequences. Proteins interact synergistically to elevate transcription rate. In b-interferon gene transcription, TFs recruit a coactivator (CBP) which is needed for transcription to occur normally. Formation of the enhanceosome and activation of RNA polymerase by coactivator are neces ...
Protein Synthesis
... 2. Discuss the significance of specific base pairing in DNA replication and in RNA synthesis. 3. Name the enzymes important in DNA and RNA synthesis. 4. Differentiate between the processes of transcription and translation. 5. Describe the roles of the 3 different types of RNA in protein synthesis. 6 ...
... 2. Discuss the significance of specific base pairing in DNA replication and in RNA synthesis. 3. Name the enzymes important in DNA and RNA synthesis. 4. Differentiate between the processes of transcription and translation. 5. Describe the roles of the 3 different types of RNA in protein synthesis. 6 ...
Genetic Testing Diseases Caused by Single Mutations with
... complex and does not provide the precise answers But what if the mutation in the BRCA1 gene occurs obtained when testing for a single gene disorder. in a cell that is developing into an egg or sperm? This is called a germ-line mutation. A child that Let's use cancer as an example. The development re ...
... complex and does not provide the precise answers But what if the mutation in the BRCA1 gene occurs obtained when testing for a single gene disorder. in a cell that is developing into an egg or sperm? This is called a germ-line mutation. A child that Let's use cancer as an example. The development re ...
• Double helix -- twisted ladder shape of DNA, like spiral staircase
... it can make correct proteins for its function (pancreas cells make insulin, etc.) 9. How might DNA technology affect you? DNA fingerprinting, identifying genetic disease or best treatment for diseases, genetically modified food ...
... it can make correct proteins for its function (pancreas cells make insulin, etc.) 9. How might DNA technology affect you? DNA fingerprinting, identifying genetic disease or best treatment for diseases, genetically modified food ...
Genetic Material The Hershey-Chase experiment was designed to
... 1. What did Hershey and Chase conclude was the genetic material of the virus? DNA ...
... 1. What did Hershey and Chase conclude was the genetic material of the virus? DNA ...
Cellular Structure and Function Handout
... ______4. If the base sequence in a segment of DNA is ATTGTC, a strand of complementary mRNA will have the sequence a. AUUGTC b. TAACAG c. UAACAG d. GACAAU ______5. The transport of substances through a membrane against a concentration gradient is accomplished by a. facilitated diffusion b. active tr ...
... ______4. If the base sequence in a segment of DNA is ATTGTC, a strand of complementary mRNA will have the sequence a. AUUGTC b. TAACAG c. UAACAG d. GACAAU ______5. The transport of substances through a membrane against a concentration gradient is accomplished by a. facilitated diffusion b. active tr ...
Mid-Term Review L4
... manila folder though!) to study from Know your vocab! Vocab will help you understand what the questions are asking – if you don’t understand the question, it makes it much more difficult to answer it. The test will be 100 multiple choice questions and a few open response ...
... manila folder though!) to study from Know your vocab! Vocab will help you understand what the questions are asking – if you don’t understand the question, it makes it much more difficult to answer it. The test will be 100 multiple choice questions and a few open response ...
a5_1_1-1_done
... 20. Tumor-suppressing genes code for proteins with what function? Preventing uncontrolled cell division. Cancer can be caused by a mutation in a tumor-suppressing gene that causes there to be too little or too much of the tumor-suppressing protein made? Too little. 21. Explain how mutations that occ ...
... 20. Tumor-suppressing genes code for proteins with what function? Preventing uncontrolled cell division. Cancer can be caused by a mutation in a tumor-suppressing gene that causes there to be too little or too much of the tumor-suppressing protein made? Too little. 21. Explain how mutations that occ ...
Effects of Transition Mutations in the Regulatory
... (1980) selected a partial revertant which proved still to harbour spo-69. This revertant was presumed by Yudkin & Turley (1980) to be a double mutant, spo-69sas-I; in the light of the present results, which show that spo-69 is itself a double mutant, we now believe that the Downloaded from www.micro ...
... (1980) selected a partial revertant which proved still to harbour spo-69. This revertant was presumed by Yudkin & Turley (1980) to be a double mutant, spo-69sas-I; in the light of the present results, which show that spo-69 is itself a double mutant, we now believe that the Downloaded from www.micro ...
Quiz 2
... - Pyrimidines – Thymine and Cytosine. RNA carries Uracil rather than Thymine – single ringed - Base pairing through complimentary base pairing with hydrogen bonds - Adenine and Thymine – two bond - Cytosine and Guanine – Three bonds - Structure – Consensation rxn builds chain of nucelotides from a p ...
... - Pyrimidines – Thymine and Cytosine. RNA carries Uracil rather than Thymine – single ringed - Base pairing through complimentary base pairing with hydrogen bonds - Adenine and Thymine – two bond - Cytosine and Guanine – Three bonds - Structure – Consensation rxn builds chain of nucelotides from a p ...
Evidence that a Safe Dose of Mutagen Does Not Exist
... 2. It has been unequivocally established that humans accumulate somatic mutations as they pass through life. This unambiguously demonstrates that repair pathways are not failsafe. 3. We now know that more than 98% of all human cancers are caused by environment-induced somatic mutations. If DNA repai ...
... 2. It has been unequivocally established that humans accumulate somatic mutations as they pass through life. This unambiguously demonstrates that repair pathways are not failsafe. 3. We now know that more than 98% of all human cancers are caused by environment-induced somatic mutations. If DNA repai ...
Chapter 15 - ShoultzScience
... The ras family of genes are the most common oncogenes implicated in human cancers. Alteration of one nucleotide pair converts a normal functioning ras proto-oncogene to an oncogene A major tumor-suppressor gene p53 is more frequently mutated in human cancers than any other known gene. The p53 protei ...
... The ras family of genes are the most common oncogenes implicated in human cancers. Alteration of one nucleotide pair converts a normal functioning ras proto-oncogene to an oncogene A major tumor-suppressor gene p53 is more frequently mutated in human cancers than any other known gene. The p53 protei ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.