Genetics Slides
... Most human traits are polygenic, which means they are controlled by multiple genes. – This leads to a wide array of phenotypes. – Simple Punnett squares do NOT work for polygenic traits. § EX: Human height & eye color. ...
... Most human traits are polygenic, which means they are controlled by multiple genes. – This leads to a wide array of phenotypes. – Simple Punnett squares do NOT work for polygenic traits. § EX: Human height & eye color. ...
Presentation
... Gene pool – total of all the allele in the population Alleles – chromosome sections that code for specific proteins traits Examples: Humans have alleles for blue eyes / brown eyes /green eyes curly/straight hair blood type A / B / O / AB ...
... Gene pool – total of all the allele in the population Alleles – chromosome sections that code for specific proteins traits Examples: Humans have alleles for blue eyes / brown eyes /green eyes curly/straight hair blood type A / B / O / AB ...
Inheritance - West East University
... Expression of Sickle-cell Disease • In sickle cell disease, at least one of the beta-globin subunits in haemoglogin is replaced with haemoglogin S • In sickle cell anaemia, the commonest form of sickle cell disease, hemoglobin S replaces both beta-globin subunits in haemoglogin – In other types of ...
... Expression of Sickle-cell Disease • In sickle cell disease, at least one of the beta-globin subunits in haemoglogin is replaced with haemoglogin S • In sickle cell anaemia, the commonest form of sickle cell disease, hemoglobin S replaces both beta-globin subunits in haemoglogin – In other types of ...
F 1 Generation
... sequence is altered • Insertion Mutation: An extra nitrogen base is added to sequence • Deletion Mutation: One nitrogen base is deleted from the sequence • Substitution Mutation: Base pairings are incorrect (ex: T&G pair or A&C pair) ...
... sequence is altered • Insertion Mutation: An extra nitrogen base is added to sequence • Deletion Mutation: One nitrogen base is deleted from the sequence • Substitution Mutation: Base pairings are incorrect (ex: T&G pair or A&C pair) ...
Causes of microevolution
... over the generations unless acted upon by agents other than sexual recombination. So sexual shuffling of alleles due to meiosis and random fertilization have no effect on the overall genetic structure of a population. ...
... over the generations unless acted upon by agents other than sexual recombination. So sexual shuffling of alleles due to meiosis and random fertilization have no effect on the overall genetic structure of a population. ...
Evidence of relationships between organisms
... DNA of the new species will initially be very similar. • Due to mutations the sequences of nucleotide bases in DNA changes. • Over time the new species will accumulate more differences in its DNA. • Therefore we would expect species that are more closely related to have more similarities in their DN ...
... DNA of the new species will initially be very similar. • Due to mutations the sequences of nucleotide bases in DNA changes. • Over time the new species will accumulate more differences in its DNA. • Therefore we would expect species that are more closely related to have more similarities in their DN ...
DNA helix mRNA strand transcription gene A > A G > G C > C T > U
... different in the children (i.e. the frequency of recombination between those two genes). This will help us estimate p and therefore d. If we are able to determine the distance between all pairs of genes in our example genome, then we can use these distances to determine the exact sequence of the gen ...
... different in the children (i.e. the frequency of recombination between those two genes). This will help us estimate p and therefore d. If we are able to determine the distance between all pairs of genes in our example genome, then we can use these distances to determine the exact sequence of the gen ...
Epidermal Growth Factor Receptor (EGFR) Mutation Analysis for
... Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (TK) frequently over-expressed and activated in non-small cell lung cancer (NSCLC). Mutations in 2 regions of the EGFR gene (exons 18-24)—small deletions in exon 19 and a point mutation in exon 21 (L858R)—appear to predict tumor r ...
... Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (TK) frequently over-expressed and activated in non-small cell lung cancer (NSCLC). Mutations in 2 regions of the EGFR gene (exons 18-24)—small deletions in exon 19 and a point mutation in exon 21 (L858R)—appear to predict tumor r ...
Vocabulary From DNA to Proteins
... Codon – a sequence of three bases of mRNA the specifies or codes for a specific amino acid to be incorporated into a protein. Certain codon signal the start and end of protein synthesis. Messenger RNA (mRNA) Molecule that is complementary to a section of DNA known as a gene, the mRNA molecule takes ...
... Codon – a sequence of three bases of mRNA the specifies or codes for a specific amino acid to be incorporated into a protein. Certain codon signal the start and end of protein synthesis. Messenger RNA (mRNA) Molecule that is complementary to a section of DNA known as a gene, the mRNA molecule takes ...
Unit1-Probesweb
... • DNA probes are pieces of DNA used to detect the presence of specific sequences in DNA. (Do not get probes mixed up with the primers used in PCR.) • What characteristics will DNA probes need to have? ...
... • DNA probes are pieces of DNA used to detect the presence of specific sequences in DNA. (Do not get probes mixed up with the primers used in PCR.) • What characteristics will DNA probes need to have? ...
Processes of Evolution
... Gene Migration: The flow into or out of a population. A split off population given enough time for natural selection to work can become another species. Adds variation to the gene pool. Gene Mutation: Change in the genetic code resulting in a mutated phenotype. The majority of mutations are not viab ...
... Gene Migration: The flow into or out of a population. A split off population given enough time for natural selection to work can become another species. Adds variation to the gene pool. Gene Mutation: Change in the genetic code resulting in a mutated phenotype. The majority of mutations are not viab ...
2nd 9 Weeks Study Guide! Aren`t you excited?? Chapter 10
... trait separate, and only ______________________________ from each pair is/are passed to the offspring. The law of independent assortment states that the inheritance of alleles for one trait is not affected by the inheritance of alleles for a different trait if the genes for the traits are on _______ ...
... trait separate, and only ______________________________ from each pair is/are passed to the offspring. The law of independent assortment states that the inheritance of alleles for one trait is not affected by the inheritance of alleles for a different trait if the genes for the traits are on _______ ...
HUMAN GENETICS ARCHITECTURE LEARNING OBJECTIVES At
... chromosome)—they are called "dominant" because a single copy—inherited from either parent—is enough to cause this trait to appear. This often means that one of the parents must also have the same trait, unless it has arisen due to a new mutation. Examples of autosomal dominant traits and disorders a ...
... chromosome)—they are called "dominant" because a single copy—inherited from either parent—is enough to cause this trait to appear. This often means that one of the parents must also have the same trait, unless it has arisen due to a new mutation. Examples of autosomal dominant traits and disorders a ...
C23 The Evolution of Populations
... 5. Natural selection Genetic drift – changes in the gene pool of a small population due to chance. Bottleneck effect – caused by a catastrophic event that leaves a small and often unrepresentative pop. to continue. (Ex. South African cheetahs/ice age/hunted to near extinction early 1900’s). ...
... 5. Natural selection Genetic drift – changes in the gene pool of a small population due to chance. Bottleneck effect – caused by a catastrophic event that leaves a small and often unrepresentative pop. to continue. (Ex. South African cheetahs/ice age/hunted to near extinction early 1900’s). ...
Questions Ch 24
... 3) Ampicillin is a semi-synthetic antibiotic derivative of penicillin G. Ampicillin is acidresistant, whereas penicillin G is not resistant to acid. Why is this important? a) Ampicillin is resistant to β-lactamases. b) Ampicillin can be taken orally. c) Ampicillin is effective against Gram-negative ...
... 3) Ampicillin is a semi-synthetic antibiotic derivative of penicillin G. Ampicillin is acidresistant, whereas penicillin G is not resistant to acid. Why is this important? a) Ampicillin is resistant to β-lactamases. b) Ampicillin can be taken orally. c) Ampicillin is effective against Gram-negative ...
BL220
... Solve and analyze genetics problems at the multi-gene level Analyze pedigrees for an unknown genetic trait Calculate chi-square values for a given set of results Identify the stages of mitosis at the microscopic level Contrast the stages of meiosis with that of mitosis Construct a DNA molecule Recog ...
... Solve and analyze genetics problems at the multi-gene level Analyze pedigrees for an unknown genetic trait Calculate chi-square values for a given set of results Identify the stages of mitosis at the microscopic level Contrast the stages of meiosis with that of mitosis Construct a DNA molecule Recog ...
lecture 2
... is transcribed from the DNA, ribosomes attach and begin translating the mRNA into protein. Thus, transcription and translation are "coupled" in prokaryotes. 2. Operons Many transcriptional units encode more than one gene, which is termed an OPERON. Genes with related functions are often located toge ...
... is transcribed from the DNA, ribosomes attach and begin translating the mRNA into protein. Thus, transcription and translation are "coupled" in prokaryotes. 2. Operons Many transcriptional units encode more than one gene, which is termed an OPERON. Genes with related functions are often located toge ...
Poxvirus - rci.rutgers.edu
... Vaccinia virus vectors • 187 kbp linear DNA genome of Vaccinia virus has more than 12 sites where additional DNA can be inserted. • Insertion of genes in these sites is by recombination at flanking homologies • Insert sizes up to 25 kbp accepted • The major use of vaccinia virus vectors is as antig ...
... Vaccinia virus vectors • 187 kbp linear DNA genome of Vaccinia virus has more than 12 sites where additional DNA can be inserted. • Insertion of genes in these sites is by recombination at flanking homologies • Insert sizes up to 25 kbp accepted • The major use of vaccinia virus vectors is as antig ...
HGMD® : Human Gene Mutation Database Example Queries for use
... PMIDs from the primary and the extra references, disease name, gene symbol, and HGVS description. Get all mutations from table “allmut” SELECT allmut.acc_num, extrarefs.acc_num, allmut.pmid, extrarefs.pmid, allmut.disease, allmut.gene, allmut.hgvs FROM allmut, extrarefs WHERE allmut.acc_num=extraref ...
... PMIDs from the primary and the extra references, disease name, gene symbol, and HGVS description. Get all mutations from table “allmut” SELECT allmut.acc_num, extrarefs.acc_num, allmut.pmid, extrarefs.pmid, allmut.disease, allmut.gene, allmut.hgvs FROM allmut, extrarefs WHERE allmut.acc_num=extraref ...
Genes and Proteins
... b. RNA polymerase catalyzes synthesis of mRNA; similar to DNA replication and DNA polymerase ...
... b. RNA polymerase catalyzes synthesis of mRNA; similar to DNA replication and DNA polymerase ...
DOC
... The topic of Molecular Genetics deals with the DNA of the cell and the process that is used to decode its genetic code and use the information to make proteins. Genes are made of DNA. The expression of DNA is protein. The term given for making a protein is called “protein synthesis.” This requires D ...
... The topic of Molecular Genetics deals with the DNA of the cell and the process that is used to decode its genetic code and use the information to make proteins. Genes are made of DNA. The expression of DNA is protein. The term given for making a protein is called “protein synthesis.” This requires D ...
1 Chapter 13: DNA, RNA, and Proteins Section 1: The Structure of
... a. At replication fork new nucleotides are added to each side b. Original 2 strands serve as template for 2 new strands ...
... a. At replication fork new nucleotides are added to each side b. Original 2 strands serve as template for 2 new strands ...
bioinformatics
... (measuring mRNA level by EST,SAGE,..tech) noise-prone (developing statistical tools to separate signal from noise).applies in tumor cells. Identification of genes that are expressed differentialy in a affected cell provide a basis for explaining the cause of illness and highlights potential drug tar ...
... (measuring mRNA level by EST,SAGE,..tech) noise-prone (developing statistical tools to separate signal from noise).applies in tumor cells. Identification of genes that are expressed differentialy in a affected cell provide a basis for explaining the cause of illness and highlights potential drug tar ...
DNA, RNA and Protein
... Question: How many electrons does carbon need to fill its outer energy level? Answer: Therefore, each carbon atom can make ____ covalent bonds with other types of atoms or additional carbons. ...
... Question: How many electrons does carbon need to fill its outer energy level? Answer: Therefore, each carbon atom can make ____ covalent bonds with other types of atoms or additional carbons. ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.