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Human karyotype
Human karyotype

... DNA is packaged into chromosomes • Each human cell contains 2 metres of DNA (3,000,000,000 bases in a haploid cell) • Nucleus is 5 microns (0.005 mm) diameter • DNA must be properly packaged, not just tangled up and stuffed into nucleus • Packaging involves coiling and folding the DNA in specific w ...
Isolating Hereditary Material
Isolating Hereditary Material

... and DNA by taking advantage of their chemical differences. Proteins contain sulfur, but DNA does not. Conversely, DNA contains phosphate, but proteins do not. Thus, when infected bacteria are grown in the presence of radioactive forms of phosphate (32P) or sulfur (35S), radioactivity can be selectiv ...
What is DNA?
What is DNA?

... geneticist, developed the first experiments to study how and why they occurred. Genetic mutations can be caused by both internal and external factors. Any factor that can cause a mutation is called a MUTAGEN (e.g. Dioxins, benzene, UV light, asbestos, DDT, cigarette smoke, x-rays etc. etc.) • Change ...
Chapter 2 need to know
Chapter 2 need to know

... also mildly affected) • Traits: Abnormal blood cells cause circulatory problems (e.g., heart enlargement) and severe anemia • Incidence: 8-9% of U.S. blacks • Outlook: Crippling, but treatable with medication ...
Web Quest
Web Quest

... *Which of these genotypes would result in a dragon with horns? (There might be ...
Molecular Genetics Close Notes Booklet
Molecular Genetics Close Notes Booklet

... Should gene therapy be reserved for treating serious diseases or should we explore the potential use for enhancing athletic ability, physical appearance, or even intelligence? Should we try to eliminate genetic defects in our children and their descendants? Should we interfere with evolution in this ...
Anatomy and Physiology BIO 137
Anatomy and Physiology BIO 137

... recessive disease even though they do not show the trait phenotypically. • Carrier screening is often used if a particular disease is common in a couple’s ethnic background or if there is a family history of the disease. • Examples of carrier tests include those for Tay-Sachs disease or sickle cell ...
Unit 7 (Molecular Biology - DNA) Study Guide KEY
Unit 7 (Molecular Biology - DNA) Study Guide KEY

... 29. What are the 4 steps to bacterial cloning? (Hint: Be sure to understand the purpose of the ampR gene on the plasmid as well as placing the bacteria in an antibiotic.) a. The first step in this process uses restriction enzymes to create “Sticky Ends” on a plasmid and DNA from another source. This ...
Document
Document

... Response of amino acid frequencies – Mutation pressure will alter the frequency of usage of codons in gene sequences. This will cause amino-acid substitutions in the proteins that will often be deleterious. Selection will therefore oppose variation in the frequencies of bases and amino acids. In mit ...
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File - Zachary Carscaddon

... 1. In theory, scientists can remove any gene from any living organism for insertion into any other living organism. ...
Recombinant DNA
Recombinant DNA

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What are macromolecules? Cells are built primarily from the largest
What are macromolecules? Cells are built primarily from the largest

... organic macromolecules are. This list is really important to understanding cells, so really memorize it well. It will pop up again and again throughout the semester. Carbohydrates are the "sugars." Both the simple sugars (like glucose and table sugar) and complex sugars (like starch). The complex su ...
Chapter 9 DNA and the Molecular Structure of Chromosomes
Chapter 9 DNA and the Molecular Structure of Chromosomes

... The DNA molecules in prokaryotic and viral chromosomes are organized into negatively supercoiled domains. Bacterial chromosomes contain circular molecules of DNA segregated into about 50 domains. ...
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L4 Recombinant DNA_cloning_HT10_eng

... • Bacteriophage λ is a virus that infects bacteria (E. coli). - a lytic and a lysogenic phase (prophage) in the life cycle. - genome size approx. 45 kb; a central region of 15 kb is not essential for replication. - have complementary single stranded cohesive ends (COS-sites); used by the phage to ma ...
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Solid Tumour Section t(6;22)(p21;q12) in undifferentiated sarcoma Atlas of Genetics and Cytogenetics

... Online updated version : http://AtlasGeneticsOncology.org/Tumors/t0622p21q12UndifID5411.html DOI: 10.4267/2042/44904 This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence. © 2010 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Review Sheet Biology 2 Evolution (chapters 15, 16) Key Words
Review Sheet Biology 2 Evolution (chapters 15, 16) Key Words

... d) biochemical (DNA, RNA, amino acid sequences) 5) Why are mutations important in the process of evolution? 6) Explain what Hox genes are and how they play a major role in the evolution of new body forms 7) Explain why an individual cannot evolve, but a population can. Use any example to illustrate ...
Lecture 1 – Mendelian inheritance
Lecture 1 – Mendelian inheritance

... outcomes in a number of trials that could each have either of two possible outcomes e.g., determining the probability of 1 female and 4 male children in a family with 5 children ...
practice exam 3_answer key
practice exam 3_answer key

... 13. During which phase of mitosis does the nuclear envelope re-form? a. anaphase b. metaphase c. prophase d. telophase e. none of the above 14. The creation of genetically identical offspring by a single parent, without the participation of sperm and egg, is called a. asexual reproduction b. sexual ...
here - IMSS Biology 2014
here - IMSS Biology 2014

... Plasticity may be expressed at behavioral, biochemical, physiological, or developmental levels with different degrees of reversibility. ...
Substrate Metabolism – Rest vs Stress
Substrate Metabolism – Rest vs Stress

... (3) glycerol -> glycerol-3-phosphate & enters glycolytic pathway (4) FFA's transported to mitochondria by carnitine carrier -> degraded to ACoA (betaoxidation) -> enters the citric acid cycle. - essential fatty acids = linolenic, linoleic & arachidonic acid - used in the production of leukotrienes, ...
Grimmer presentation
Grimmer presentation

... Business Center (DoI/ICB) contract number D15PC0002. The U.S. Government is authorized to reproduce and distribute reprints for Governmental purposes notwithstanding any copyright annotation thereon. ...
GENOMIC INSTABILITY: PHENOMENA AND ITS ROLE IN CANCER
GENOMIC INSTABILITY: PHENOMENA AND ITS ROLE IN CANCER

... [email protected] DNA is not a stable molecule, chromosomes are not stable structures and chromosomal breaks can be increased by ionizing radiation. However, it was accepted for a long time that radiation-induced chromosomal breaks are expressed in the first mitosis after radiation exposure ...
Slide 2
Slide 2

... • Explaining human behavior in terms of genes is much more difficult because behavior is so complex – no behavior can be explained in terms of different alleles of a single gene. • Before looking for gene alleles that might help explain variability in behavior, researchers must first find evidence t ...
Bellwork:
Bellwork:

... SUMMARY: 5 Steps of Protein Synthesis 1. Transcription: DNA makes RNA (in the nucleus) 2. RNA now becomes mRNA which will leave the nucleus (take the code to ribosome) 3. mRNA tells ribosomes what proteins to make 4. mRNA attaches to ribosome and forms a pattern (codon) to make a protein 5. tRNA in ...
one gene - Central Magnet School
one gene - Central Magnet School

... condition and has the genotype Ss (where “s” is the recessive sickle cell allele). Each parent passes one allele to the child, so there is a 25% chance that the child will have sickle cell disease. ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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