Brain Oscillations Control Timing of Single
... Neuroscience Graduate Group and 2Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, 3Center for Cognitive Neurosciences, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, University of California School of Medicine, Los Angeles, California 900 ...
... Neuroscience Graduate Group and 2Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, 3Center for Cognitive Neurosciences, Semel Institute, Department of Psychiatry and Biobehavioral Sciences, University of California School of Medicine, Los Angeles, California 900 ...
Mild Traumatic Brain Injury
... • Research has repeatedly demonstrated that in the civilian population, the vast majority of individuals who sustain a concussion completely recover in a matter of days to weeks. ▫ 80-90% recover in 7-10 days ▫ 3% experience persistent symptoms beyond one to ...
... • Research has repeatedly demonstrated that in the civilian population, the vast majority of individuals who sustain a concussion completely recover in a matter of days to weeks. ▫ 80-90% recover in 7-10 days ▫ 3% experience persistent symptoms beyond one to ...
Cerebellar Abnormalities Based on Chemical Neuroanatomy
... all of them are known to be expressed in the mouse cerebellum [15,19,25]. In the rolling mouse cerebellum, RyR1 expression in Purkinje cells was uniformly reduced through all cerebellar lobules [47]. Such expressional change in RyR1 may be linked with the expression of the mutated Cav2.1 channel bec ...
... all of them are known to be expressed in the mouse cerebellum [15,19,25]. In the rolling mouse cerebellum, RyR1 expression in Purkinje cells was uniformly reduced through all cerebellar lobules [47]. Such expressional change in RyR1 may be linked with the expression of the mutated Cav2.1 channel bec ...
... with normal lung function, EIA could be prevented very effectively by sodium cromoglycate, but the dose required varied between patients. For patients with severe EIA, doubling the dose of ~2-adrenoceptor agonist or sodium cromoglycate, or using them in combination, was shown to be effective. Anecdo ...
Poster
... so they included a valine where Asp44 is supposed to be. It is known that Gemin-2 contains Arg213 which interacts with Asp44 on the SMN protein. In patients with SMA, the genetic mutation causes a valine to replace Asp44 and a disruption in the ionic bond holding SMN and Gemin-2 together occurs. Gem ...
... so they included a valine where Asp44 is supposed to be. It is known that Gemin-2 contains Arg213 which interacts with Asp44 on the SMN protein. In patients with SMA, the genetic mutation causes a valine to replace Asp44 and a disruption in the ionic bond holding SMN and Gemin-2 together occurs. Gem ...
Thomas A. Woolsey
... Central Nervous System was prepared to help students and professionals understand the normal human brain and guide interpretation of clinical and experimental work. Clear charts and maps of biological structures have been teaching aids from the earliest times. In the biological sciences, the first ...
... Central Nervous System was prepared to help students and professionals understand the normal human brain and guide interpretation of clinical and experimental work. Clear charts and maps of biological structures have been teaching aids from the earliest times. In the biological sciences, the first ...
Appendix S5.
... ultimately death. The underlying molecular biology for this mode of action on nematodes has primarily been studied using a forward genetic screen with C. elegans mutants resistant to the action of AADs. Of 44 resistance alleles isolated, 36 fell into a single complementation group containing two gen ...
... ultimately death. The underlying molecular biology for this mode of action on nematodes has primarily been studied using a forward genetic screen with C. elegans mutants resistant to the action of AADs. Of 44 resistance alleles isolated, 36 fell into a single complementation group containing two gen ...
Modelling Cerebellar Function in Saccadic Adaptation
... In some respects animal movements better than robot movement Could in part be due to characteristics of biological control algorithms Which region of the brain particularly concerned with skilled movement? ...
... In some respects animal movements better than robot movement Could in part be due to characteristics of biological control algorithms Which region of the brain particularly concerned with skilled movement? ...
Adverse Drug Interactions In Dental Practice
... to epinephrine. By blocking vasodilating β2 receptors in the blood vessels of skeletal muscle and other tissues, propranolol causes epinephrine to act vascularly as a pure α-adrenergic stimulant.17-19 Peripheral resistance, which normally falls after moderate doses of epinephrine are administered, r ...
... to epinephrine. By blocking vasodilating β2 receptors in the blood vessels of skeletal muscle and other tissues, propranolol causes epinephrine to act vascularly as a pure α-adrenergic stimulant.17-19 Peripheral resistance, which normally falls after moderate doses of epinephrine are administered, r ...
The dopamine reuptake inhibitor MRZ
... neurological disorders, e.g. major depression, schizophrenia, multiple sclerosis or inflammatory disease (Friedman et al., 2011; Salamone and Correa, 2012). For instance, in a test of effort-related choice, patients with major depressive disorders were less willing to expend effort for rewards than c ...
... neurological disorders, e.g. major depression, schizophrenia, multiple sclerosis or inflammatory disease (Friedman et al., 2011; Salamone and Correa, 2012). For instance, in a test of effort-related choice, patients with major depressive disorders were less willing to expend effort for rewards than c ...
Therapeutic drug monitoring
... functions are potential sources of pharmacokinetics with respect to age. Infants are defined as children (0-2) years of age .infants less than 4 weeks old special consideration is necessary because their ability to handle drugs differ from more mature infants. Until the third week of life, hepat ...
... functions are potential sources of pharmacokinetics with respect to age. Infants are defined as children (0-2) years of age .infants less than 4 weeks old special consideration is necessary because their ability to handle drugs differ from more mature infants. Until the third week of life, hepat ...
No Slide Title
... Efficacy in mania established Usually well-tolerated Cons: ? Efficacy in prophylaxis Ataxia and neurocognitive effects, weight gain, nausea, hair loss, leukopenia, hepatotoxicity, Na, hepatic enzyme induction ...
... Efficacy in mania established Usually well-tolerated Cons: ? Efficacy in prophylaxis Ataxia and neurocognitive effects, weight gain, nausea, hair loss, leukopenia, hepatotoxicity, Na, hepatic enzyme induction ...
Segregated Cell Populations Enable Distinct Parallel Encoding
... function of the cell layer’s depth [51]. On one hand, the cannabinoid type-1 receptors (CB1R) can modulate the release of excitatory or inhibitory neurotransmitter upon their activation [52, 53]. On the other hand, HCN channels mediate the hyperpolarizationactivated cationic depolarizing current (I ...
... function of the cell layer’s depth [51]. On one hand, the cannabinoid type-1 receptors (CB1R) can modulate the release of excitatory or inhibitory neurotransmitter upon their activation [52, 53]. On the other hand, HCN channels mediate the hyperpolarizationactivated cationic depolarizing current (I ...
Caffeine, Acting on Adenosine A1 Receptors, Prevents the
... poorly self-administered (Griffiths and Woodson, 1988; Gauvin et al., 1990). However, cocaine substituted for the caffeine-discriminative stimulus in rats trained to discriminate caffeine from saline (Holtzman, 1986). Thus, how caffeine and cocaine can substitute for each other, and to what extent, ...
... poorly self-administered (Griffiths and Woodson, 1988; Gauvin et al., 1990). However, cocaine substituted for the caffeine-discriminative stimulus in rats trained to discriminate caffeine from saline (Holtzman, 1986). Thus, how caffeine and cocaine can substitute for each other, and to what extent, ...
Burst Firing and Modulation of Functional Connectivity in Cat Striate
... Strehler 1987; Richmond et al. 1990). The challenge in the study of pattern-based representation of information lies not only in finding representation schemes but also in elucidating mechanisms by which these schemes can be decoded. Even though more information could be encoded in random patterns t ...
... Strehler 1987; Richmond et al. 1990). The challenge in the study of pattern-based representation of information lies not only in finding representation schemes but also in elucidating mechanisms by which these schemes can be decoded. Even though more information could be encoded in random patterns t ...
WCBR 2015 Panel Schedule - Winter Conference on Brain Research
... Recent Findings in the Regulation of Depressed Mood by Glutamate Receptors. Non-coding RNA in brain development and disorders Controversies in Ictogenesis and Epileptogenesis Intracellular signaling mechanisms affecting alcohol actions and drinking behavior Parkinson’s disease genes, pathways, and t ...
... Recent Findings in the Regulation of Depressed Mood by Glutamate Receptors. Non-coding RNA in brain development and disorders Controversies in Ictogenesis and Epileptogenesis Intracellular signaling mechanisms affecting alcohol actions and drinking behavior Parkinson’s disease genes, pathways, and t ...
TMP Booklet 2012C.indd - Keck Graduate Institute
... biomedical institution dedicated to the treatment and prevention of cancer and life-threatening diseases. With the support of humanitarian philanthropies and collaborations worldwide, the City of Hope researches innovative drugs and technologies to treat diseases such as cancer and diabetes. In supp ...
... biomedical institution dedicated to the treatment and prevention of cancer and life-threatening diseases. With the support of humanitarian philanthropies and collaborations worldwide, the City of Hope researches innovative drugs and technologies to treat diseases such as cancer and diabetes. In supp ...
Loss of Neurons in Magnocellular and Parvocellular Layers of the
... to the nonglaucomatous left eye. To determine whether neurons are lost in magnocellular and/or parvocellular LGN layers connected to a glaucomatous eye, neurons in the left LGN layers 1, 4, and 6 were counted, and the counts were compared with those from the left LGN layers 1, 4, and 6 in control mo ...
... to the nonglaucomatous left eye. To determine whether neurons are lost in magnocellular and/or parvocellular LGN layers connected to a glaucomatous eye, neurons in the left LGN layers 1, 4, and 6 were counted, and the counts were compared with those from the left LGN layers 1, 4, and 6 in control mo ...
Neurobiological Mechanisms Underlying Oestradiol Negative and
... ERa that prevent only its association with oestrogen response elements, but leave other genomic and non-genomic signalling modalities intact, do not exhibit the oestradiol-induced changes in GnRH neurone activity that wild-type mice do (33, 34). These data, in combination with the failure of the vas ...
... ERa that prevent only its association with oestrogen response elements, but leave other genomic and non-genomic signalling modalities intact, do not exhibit the oestradiol-induced changes in GnRH neurone activity that wild-type mice do (33, 34). These data, in combination with the failure of the vas ...
Nonlinear brain dynamics as macroscopic manifestation of
... "...some widely held views [of memory] have to be completely discarded, and none more completely than that which treats recall as the re-excitement in some way of fixed and changeless 'traces' " (p. vi). On empirical grounds John (2001) inferred: “…consciousness is a property of quantum-like process ...
... "...some widely held views [of memory] have to be completely discarded, and none more completely than that which treats recall as the re-excitement in some way of fixed and changeless 'traces' " (p. vi). On empirical grounds John (2001) inferred: “…consciousness is a property of quantum-like process ...
Brain Stimulation for Neurological and Psychiatric Disorders
... study that indicated that high-frequency stimulation can simultaneously suppress cell bodies and excite axons (McIntyre and Grill, 1999). Together with the finding that STN high-frequency stimulation induced increase in glutamate release in the SNr (Windels et al., 2000), these results suggest that ...
... study that indicated that high-frequency stimulation can simultaneously suppress cell bodies and excite axons (McIntyre and Grill, 1999). Together with the finding that STN high-frequency stimulation induced increase in glutamate release in the SNr (Windels et al., 2000), these results suggest that ...
Chapter 5 Drug Tests: Their Uses And Limitations
... window of detection, with most drugs being detectable within several hours only. This characteristic renders it suitable for w determining very recent drug abuse, but weakens its ability in detecting use over time. For example, someone administered heroin a day ago is likelyy to be tested negative b ...
... window of detection, with most drugs being detectable within several hours only. This characteristic renders it suitable for w determining very recent drug abuse, but weakens its ability in detecting use over time. For example, someone administered heroin a day ago is likelyy to be tested negative b ...
Angiotensin-Converting Enzyme Inhibitors
... Angiotensin receptors of AT1 subtype are the target of the new drugs ...
... Angiotensin receptors of AT1 subtype are the target of the new drugs ...
Neuronal Diversity and Temporal Dynamics: The Unity of
... time. Interestingly, different types of parvalbumin (PV)–expressing, GABAergic interneuron also innervate distinct subcellular domains: Axo-axonic cells (Fig. 1, type 1) innervate exclusively the axoninitial segment of pyramidal cells; basket cells (Fig. 1, type 2) innervate the cell bodies and prox ...
... time. Interestingly, different types of parvalbumin (PV)–expressing, GABAergic interneuron also innervate distinct subcellular domains: Axo-axonic cells (Fig. 1, type 1) innervate exclusively the axoninitial segment of pyramidal cells; basket cells (Fig. 1, type 2) innervate the cell bodies and prox ...