Stereological estimation of dendritic coverage in the capybara SCG
... occupied by synaptic axon profiles by using a combination of electron-immunohistochemical labelling for synaptophysin and applying a design-based stereological methodology. Based on an allometric analysis, which took into account the SCG volume, we have previously predicted some 34.1 billion axo-den ...
... occupied by synaptic axon profiles by using a combination of electron-immunohistochemical labelling for synaptophysin and applying a design-based stereological methodology. Based on an allometric analysis, which took into account the SCG volume, we have previously predicted some 34.1 billion axo-den ...
Effect of pH on Metabolism and Ultrastructure of Guinea Pig
... of 0.6 (from 7.1 to 6.5) has been calculated to occur in tissue as a result of oxygen deprivation which may be sufficient to produce deleterious effects on neural metabolism and activity. The acidosis may thus compound the damaging effect of oxygen deprivation. pH has an additional biological import ...
... of 0.6 (from 7.1 to 6.5) has been calculated to occur in tissue as a result of oxygen deprivation which may be sufficient to produce deleterious effects on neural metabolism and activity. The acidosis may thus compound the damaging effect of oxygen deprivation. pH has an additional biological import ...
Bioisosterism: A Rational Approach in Drug Design
... a Concentration of compound that decreased specific binding of 1.5 nM [3H]diazepam to rat brain receptors by 50%. ...
... a Concentration of compound that decreased specific binding of 1.5 nM [3H]diazepam to rat brain receptors by 50%. ...
M&E and the Frontal Lobes
... When an individual is aware of the beginning, it may be thought of as a warning or aura. On the other hand, an individual may not be aware of the beginning and therefore have no warning. Sometimes, the warning or aura is not followed by any other symptoms. It may be considered a simple partial s ...
... When an individual is aware of the beginning, it may be thought of as a warning or aura. On the other hand, an individual may not be aware of the beginning and therefore have no warning. Sometimes, the warning or aura is not followed by any other symptoms. It may be considered a simple partial s ...
Simvastatin protects ischemic spinal cord injury from cell death and
... neurologic recovery after cerebral ischemia in experimental animal models and in vitro cellular models [15–18]. Statins are frequently used as cholesterol-lowering agents, but their protective effect against ischemia depends on other actions as well [19], including modification of oxidative stress [ ...
... neurologic recovery after cerebral ischemia in experimental animal models and in vitro cellular models [15–18]. Statins are frequently used as cholesterol-lowering agents, but their protective effect against ischemia depends on other actions as well [19], including modification of oxidative stress [ ...
FUNCTIONAL NEUROANATOMY OF SPINAL CORD LEARNING
... Carries pain and temperature sensations which are transmitted in fast conducting delta A type and slow C type fibres. Posterior root ganglion → Tip of posterior gray column → Posteriolateral tract of Lissauer → Synapse in posterior column. Second order neuron axon cross obliquely to opposite side in ...
... Carries pain and temperature sensations which are transmitted in fast conducting delta A type and slow C type fibres. Posterior root ganglion → Tip of posterior gray column → Posteriolateral tract of Lissauer → Synapse in posterior column. Second order neuron axon cross obliquely to opposite side in ...
Using calcium imaging to understand function and learning in L2/3
... major component of responsiveness is independent of experimental stimulus choice. The distribution of responsivity was skewed, indicating the existence of a small population of highly-‐ responsive neurons. Highly-‐r ...
... major component of responsiveness is independent of experimental stimulus choice. The distribution of responsivity was skewed, indicating the existence of a small population of highly-‐ responsive neurons. Highly-‐r ...
FUNCTIONAL NEUROANATOMY OF SPINAL CORD LEARNING
... Carries pain and temperature sensations which are transmitted in fast conducting delta A type and slow C type fibres. Posterior root ganglion → Tip of posterior gray column → Posteriolateral tract of Lissauer → Synapse in posterior column. Second order neuron axon cross obliquely to opposite side in ...
... Carries pain and temperature sensations which are transmitted in fast conducting delta A type and slow C type fibres. Posterior root ganglion → Tip of posterior gray column → Posteriolateral tract of Lissauer → Synapse in posterior column. Second order neuron axon cross obliquely to opposite side in ...
Drug effects on salivary glands: dry mouth
... cholinergic, and alpha1-adrenergic receptor sites, causing ADRs such as dry mouth, weight gain, constipation, drowsiness, and dizziness. Measurement of the inhibitory effect on spontaneous whole mouth and parotid salivation after administration of various antidepressants divides them into (a) isocarb ...
... cholinergic, and alpha1-adrenergic receptor sites, causing ADRs such as dry mouth, weight gain, constipation, drowsiness, and dizziness. Measurement of the inhibitory effect on spontaneous whole mouth and parotid salivation after administration of various antidepressants divides them into (a) isocarb ...
Aspartame - Pacific Rim Quiropraxia
... 1) is not fully developed during childhood, 2) does not fully protect all areas of the brain, 3) is damaged by numerous chronic and acute conditions, and 4) allows seepage of excess glutamate and aspartate into the brain even when intact. The excess glutamate and aspartate slowly begin to destroy ne ...
... 1) is not fully developed during childhood, 2) does not fully protect all areas of the brain, 3) is damaged by numerous chronic and acute conditions, and 4) allows seepage of excess glutamate and aspartate into the brain even when intact. The excess glutamate and aspartate slowly begin to destroy ne ...
1-Student`s Refexes
... (1) Monosynaptic Reflexes المنعكسات أحادية المشبك: – have one synapse only : The sensory ( afferent ) axon synapse directly on the anterior horn cell. –Therefore , the reflex arc does not contain interneurons . –Examples : The Stretch ( Tendon ) reflexes ( also called Tendon Jerks ). ...
... (1) Monosynaptic Reflexes المنعكسات أحادية المشبك: – have one synapse only : The sensory ( afferent ) axon synapse directly on the anterior horn cell. –Therefore , the reflex arc does not contain interneurons . –Examples : The Stretch ( Tendon ) reflexes ( also called Tendon Jerks ). ...
In understanding the affects of the psychoactive drugs to be
... Marijuana has been shown to increase the heart rate by as much as 50%, as well as increasing the blood pressure in some people. However, research suggests that these changes do not create permanent harmful effects on normal hearts and blood vessels and are virtually insignificant among healthy peopl ...
... Marijuana has been shown to increase the heart rate by as much as 50%, as well as increasing the blood pressure in some people. However, research suggests that these changes do not create permanent harmful effects on normal hearts and blood vessels and are virtually insignificant among healthy peopl ...
The Peripheral Nervous System
... Reflex Arcs • Although the somatic nervous system is generally under conscious control, some actions of the system occur automatically. • For example, if you accidentally step on a tack with your bare foot, your leg may recoil before you are even aware of the pain. • This rapid response (a reflex) i ...
... Reflex Arcs • Although the somatic nervous system is generally under conscious control, some actions of the system occur automatically. • For example, if you accidentally step on a tack with your bare foot, your leg may recoil before you are even aware of the pain. • This rapid response (a reflex) i ...
Lec. 5 - Overview of.. - College of Pharmacy at Howard University
... Macrolide Mechanism of Action Reversibly bind to the P-site on the 50s ribosomal subunit of susceptible bacteria This inhibits the action of peptidyl transferase, which is responsible for elongation of the growing peptide chain Bacteria is unable therefore unable to synthesize protein, and will ...
... Macrolide Mechanism of Action Reversibly bind to the P-site on the 50s ribosomal subunit of susceptible bacteria This inhibits the action of peptidyl transferase, which is responsible for elongation of the growing peptide chain Bacteria is unable therefore unable to synthesize protein, and will ...
Pharmacokinetics
... Phase II • Conjugation reaction with an endogenous substrate, such as glucuronic acid, sulfuric acid, acetic acid, or an amino acid, results in polar, usually more water-soluble compounds that are most often therapeutically inactive • A notable exception is morphine-6-glucuronide, which is more pot ...
... Phase II • Conjugation reaction with an endogenous substrate, such as glucuronic acid, sulfuric acid, acetic acid, or an amino acid, results in polar, usually more water-soluble compounds that are most often therapeutically inactive • A notable exception is morphine-6-glucuronide, which is more pot ...
Dispersed systems
... The use of a combination of ion exchange resin complex and particle coating has resulted in product success via the so-called Pennkinetic system. By this technique, ionic drugs are complexed with ion exchange resins, and the drug–resin complex particles coated with ethylcellulose. In liquid formulat ...
... The use of a combination of ion exchange resin complex and particle coating has resulted in product success via the so-called Pennkinetic system. By this technique, ionic drugs are complexed with ion exchange resins, and the drug–resin complex particles coated with ethylcellulose. In liquid formulat ...
12
... must be pacified to reduce their in vivo toxicity (30-33). In addition, their polyamidoamine linkage is resistant to degradation in the body. Another well-known dendritic system is based on the polyaryl ether convergent dendrimers (34). Although promising preliminary studies were performed with the ...
... must be pacified to reduce their in vivo toxicity (30-33). In addition, their polyamidoamine linkage is resistant to degradation in the body. Another well-known dendritic system is based on the polyaryl ether convergent dendrimers (34). Although promising preliminary studies were performed with the ...
PDF+Links
... 1996; Castel-Barthe et al., 1996), suggesting that age-related pathological brain dysfunction might be ameliorated by treatment with neurotrophic factor. Most of earlier studies usually estimated degenerative or atrophic changes in morphology of the cholinergic neurons. However, recently attention h ...
... 1996; Castel-Barthe et al., 1996), suggesting that age-related pathological brain dysfunction might be ameliorated by treatment with neurotrophic factor. Most of earlier studies usually estimated degenerative or atrophic changes in morphology of the cholinergic neurons. However, recently attention h ...
The Brain - Personal
... Functional Areas of the Cerebral Cortex • The three types of functional areas are: • Motor areas—control voluntary movement • Sensory areas—conscious awareness of sensation • Association areas—integrate diverse information ...
... Functional Areas of the Cerebral Cortex • The three types of functional areas are: • Motor areas—control voluntary movement • Sensory areas—conscious awareness of sensation • Association areas—integrate diverse information ...
Gene therapy for optic nerve disease
... promising treatment modality. Safer vectors are being developed that are capable of long-term transgene expression in host cells. Understanding of the mechanisms by which vectors mediate integration of genes into the host geneome is also improving, with the aim of developing vectors with reduced ris ...
... promising treatment modality. Safer vectors are being developed that are capable of long-term transgene expression in host cells. Understanding of the mechanisms by which vectors mediate integration of genes into the host geneome is also improving, with the aim of developing vectors with reduced ris ...
Antibiotics - DENTISTRY 2012
... against Gram(-) bacteria with reduced activity against Gram-positive organisms. Bactericidal and work in the same way as the penicillins by interfering with the cell-wall. Only a few cephalosporins are administered orally , e.g. cephalexin, most are administered IM or IV. Their t½ are short & excret ...
... against Gram(-) bacteria with reduced activity against Gram-positive organisms. Bactericidal and work in the same way as the penicillins by interfering with the cell-wall. Only a few cephalosporins are administered orally , e.g. cephalexin, most are administered IM or IV. Their t½ are short & excret ...
Overview of Antimicrobial Agents
... Macrolide Mechanism of Action Reversibly bind to the P-site on the 50s ribosomal subunit of susceptible bacteria This inhibits the action of peptidyl transferase, which is responsible for elongation of the growing peptide chain Bacteria is unable therefore unable to synthesize protein, and will ...
... Macrolide Mechanism of Action Reversibly bind to the P-site on the 50s ribosomal subunit of susceptible bacteria This inhibits the action of peptidyl transferase, which is responsible for elongation of the growing peptide chain Bacteria is unable therefore unable to synthesize protein, and will ...
Identification of novel therapeutics for complex diseases from
... ability to effectively translate this data to the clinic has not kept pace. Over the past 60 years, pharmaceutical companies have successfully demonstrated the safety and efficacy of over 1,200 novel therapeutic drugs via costly clinical studies. While this process must continue, better use can be m ...
... ability to effectively translate this data to the clinic has not kept pace. Over the past 60 years, pharmaceutical companies have successfully demonstrated the safety and efficacy of over 1,200 novel therapeutic drugs via costly clinical studies. While this process must continue, better use can be m ...