GATE 2009 Pharmaceutical Sciences Question Paper
... Quaternary structure in protein molecules refers to the (A) Arrangement of multiple domains in a single polypeptide chain (B) Specific arrangement of multiple subunits in multi-subunit proteins (C) Formation of molten globules (D) Protein folding in single subunit prot eins ...
... Quaternary structure in protein molecules refers to the (A) Arrangement of multiple domains in a single polypeptide chain (B) Specific arrangement of multiple subunits in multi-subunit proteins (C) Formation of molten globules (D) Protein folding in single subunit prot eins ...
Dorsal spinal cord stimulation obtunds the capacity of intrathoracic
... by neurons in that ganglion was identified using methods that have been described previously (6; 11). The recording microelectrode utilized had a 250-µm shank diameter, an exposed tip of 10 µm and an impedance of 9-11 MΩ at 1,000 Hz (Frederick Haer & Co., model #ME 25-10-2). The indifferent electrod ...
... by neurons in that ganglion was identified using methods that have been described previously (6; 11). The recording microelectrode utilized had a 250-µm shank diameter, an exposed tip of 10 µm and an impedance of 9-11 MΩ at 1,000 Hz (Frederick Haer & Co., model #ME 25-10-2). The indifferent electrod ...
Opioid analgesics
... in prehistorical times (e.g. in Egypt, Ebers’Papyrus – XVI BC) as an analgesic, tranquillizer, antitussive drug, and for treating diarrhoea. The principal active ingredient in crude opium – morphine, was isolated in 1806 from Frederic Sertűrner, who tested pure drug on himself and three young men. H ...
... in prehistorical times (e.g. in Egypt, Ebers’Papyrus – XVI BC) as an analgesic, tranquillizer, antitussive drug, and for treating diarrhoea. The principal active ingredient in crude opium – morphine, was isolated in 1806 from Frederic Sertűrner, who tested pure drug on himself and three young men. H ...
TRANSIENT SHORTENING OF MICROVILLI INDUCED BY
... microvilli become longer and narrower and preare not static structures, but probably represent a sumably increase in number per cell (1) . These steady state governed by rates of synthesis and morphological alterations are accompanied by degradation of their molecular components (4) . marked changes ...
... microvilli become longer and narrower and preare not static structures, but probably represent a sumably increase in number per cell (1) . These steady state governed by rates of synthesis and morphological alterations are accompanied by degradation of their molecular components (4) . marked changes ...
Propagation of cortical synfire activity: survival probability in single
... packet input, was computed. Interpreting a and s as deterministic state variables, we could predict the propagation of synchronous activity in a syn®re chain network on the basis of the transmission function. Practically identical results were obtained for a reduced integrate-and-®re model, demonstr ...
... packet input, was computed. Interpreting a and s as deterministic state variables, we could predict the propagation of synchronous activity in a syn®re chain network on the basis of the transmission function. Practically identical results were obtained for a reduced integrate-and-®re model, demonstr ...
... Alliance argues that, because the Petitioner had not tried all seven of its approved ADHD drugs, Intuniv was not medically necessary. (Although according to the Petitioner's doctor, she had tried, without success, two of those approved drugs, Clonidine and Focalin.) The question of whether Intuniv i ...
Lecture 14
... you want (the Target), since all the weights are random. We then calculate the Error of each neuron, which is essentially: Target Actual Output (i.e., What you want - What you actually get). This error is then used mathematically to change the weights in such a way that the error will get smaller. I ...
... you want (the Target), since all the weights are random. We then calculate the Error of each neuron, which is essentially: Target Actual Output (i.e., What you want - What you actually get). This error is then used mathematically to change the weights in such a way that the error will get smaller. I ...
Blood clots
... smaller pieces, dislodge from the location where it was initially formed.) An embolus is a blood clot, piece/globule of fatty deposit, or other object that is carried through the bloodstream. An embolism refers to the obstruction of a blood vessel by a foreign substance or a blood clot that trav ...
... smaller pieces, dislodge from the location where it was initially formed.) An embolus is a blood clot, piece/globule of fatty deposit, or other object that is carried through the bloodstream. An embolism refers to the obstruction of a blood vessel by a foreign substance or a blood clot that trav ...
Document
... • Raises blood glucose levels • Mobilizes fat as a food source • Stimulates the reticular activating system (RAS) of the brain, increasing mental alertness ...
... • Raises blood glucose levels • Mobilizes fat as a food source • Stimulates the reticular activating system (RAS) of the brain, increasing mental alertness ...
Review of Antibody-Drug Conjugates, Methods in Molecular Biology
... of the targets, the better understanding of ADC mechanism of action and the understanding of ADC off-target toxicities. Last but not least, the selection of appropriate clinical settings, including the patient selection and the dosing regimen, is also discussed. The critical factors for target selec ...
... of the targets, the better understanding of ADC mechanism of action and the understanding of ADC off-target toxicities. Last but not least, the selection of appropriate clinical settings, including the patient selection and the dosing regimen, is also discussed. The critical factors for target selec ...
Origins of Behavioral Neuroscience 1.1 Multiple Choice 1) The mind
... 25) Which of the following statements is consistent with how a physiological psychologist would solve the problem of how the mind and body interact? A) The mind is a product produced by the operations of the nervous system. B) The body can influence the mind through the actions of the pineal gland. ...
... 25) Which of the following statements is consistent with how a physiological psychologist would solve the problem of how the mind and body interact? A) The mind is a product produced by the operations of the nervous system. B) The body can influence the mind through the actions of the pineal gland. ...
Understanding Key Determinants of Drug Activity
... clinical drug administration. On the other hand, a more complex phenomenon that can lead to drug interactions is enzyme induction. This entails increased transcription and synthesis of enzyme proteins, resulting in augmented catalytic activity. Enzyme induction often leads to enhanced clearance of d ...
... clinical drug administration. On the other hand, a more complex phenomenon that can lead to drug interactions is enzyme induction. This entails increased transcription and synthesis of enzyme proteins, resulting in augmented catalytic activity. Enzyme induction often leads to enhanced clearance of d ...
studies on formulation and evaluation of floating tablet
... Nizatidine is having a half-life of 1-2 hrs. The bioavailability of Nizatidine is approximately 85% with little intersubject variations. The serum concentration reaches its peak (c) within 1-2 hrs after oral administration.3 Oral delivery of drugs is by far the most preferable route of drug delivery ...
... Nizatidine is having a half-life of 1-2 hrs. The bioavailability of Nizatidine is approximately 85% with little intersubject variations. The serum concentration reaches its peak (c) within 1-2 hrs after oral administration.3 Oral delivery of drugs is by far the most preferable route of drug delivery ...
Drug Abuse Education Course
... • 34.8% are using five times a week. • 74.2% of illicit drug users are using marijuana. – 54.5% use only marijuana. – 19.6% use marijuana and another illicit drug. ...
... • 34.8% are using five times a week. • 74.2% of illicit drug users are using marijuana. – 54.5% use only marijuana. – 19.6% use marijuana and another illicit drug. ...
Different populations of neurons contribute to the detection and
... not raised by adaptation close to the test direction, but rather by adaptation 40 – 60° off it. This is in agreement with the observation that the discrimination signal is highest about one tuning half-width from the preferred direction of a neuron (Fig. 1b). In primate visual cortex, these tuning h ...
... not raised by adaptation close to the test direction, but rather by adaptation 40 – 60° off it. This is in agreement with the observation that the discrimination signal is highest about one tuning half-width from the preferred direction of a neuron (Fig. 1b). In primate visual cortex, these tuning h ...
6_ARV_Drug_Toxicity
... Side Effects and Toxicities • Side effects are usually self-limited and not life-threatening, and usually resolve over a short period of time and with symptomatic support. Side effects usually occur early after ARV initiation. • Toxicities are more severe, potentially lifethreatening effects of ARV ...
... Side Effects and Toxicities • Side effects are usually self-limited and not life-threatening, and usually resolve over a short period of time and with symptomatic support. Side effects usually occur early after ARV initiation. • Toxicities are more severe, potentially lifethreatening effects of ARV ...
CHRONIC PAIN
... i. A characteristic pattern implanted by the patterns of repeated cyclic processing and synthesis of nerve impulses throughout the neuromatrix Sentient neural hub i. The area of the brain in which the stream of nerve impulses is converted into a continuously changing stream of awareness and ...
... i. A characteristic pattern implanted by the patterns of repeated cyclic processing and synthesis of nerve impulses throughout the neuromatrix Sentient neural hub i. The area of the brain in which the stream of nerve impulses is converted into a continuously changing stream of awareness and ...
Neural correlates of consciousness: A definition of the dorsal and
... mate visual hierarchy. The dorsal stream is often described as the ‘where’ pathway serving spatial information that allows us to navigate the environment or pick up an object. The ventral stream, on the other hand, serves object recognition, the so-called ‘what’ pathway. This concept of brain archit ...
... mate visual hierarchy. The dorsal stream is often described as the ‘where’ pathway serving spatial information that allows us to navigate the environment or pick up an object. The ventral stream, on the other hand, serves object recognition, the so-called ‘what’ pathway. This concept of brain archit ...
Marijuana Information marijuana
... the United States first among 17 European and North American countries for prevalence of marijuana use. And more users start every day. In 2008, an estimated 2.2 million Americans used marijuana for the first time; greater than half were under age 18. The use of marijuana can produce adverse physica ...
... the United States first among 17 European and North American countries for prevalence of marijuana use. And more users start every day. In 2008, an estimated 2.2 million Americans used marijuana for the first time; greater than half were under age 18. The use of marijuana can produce adverse physica ...
A functional magnetic resonance study
... The results from seed thalamus supported some previous studies, in which it showed abnormal structure and function of thalamus.4,5 In this study, thalamus was chose as seed region based on a latest interesting finding, which showed significantly lower regional homogeneity in the left thalamus in MDD ...
... The results from seed thalamus supported some previous studies, in which it showed abnormal structure and function of thalamus.4,5 In this study, thalamus was chose as seed region based on a latest interesting finding, which showed significantly lower regional homogeneity in the left thalamus in MDD ...
19 TROCHLEAR NUCLEUS (C.N. IV)
... The oculomotor nucleus proper is comprised of cells that innervate all extraocular eye muscles except the lateral rectus (LR6) and superior oblique (SO4). Remember that it also innervates the levator palpebrae. The EDINGER-WESTPHAL nucleus, which lies dorsal to the oculomotor nucleus proper, contain ...
... The oculomotor nucleus proper is comprised of cells that innervate all extraocular eye muscles except the lateral rectus (LR6) and superior oblique (SO4). Remember that it also innervates the levator palpebrae. The EDINGER-WESTPHAL nucleus, which lies dorsal to the oculomotor nucleus proper, contain ...
12 - William M. Clark, M.D
... • Death may occur due to paralysis of respiratory muscles or cardiac arrest • Survivors often develop postpolio syndrome many years later, as neurons are lost ...
... • Death may occur due to paralysis of respiratory muscles or cardiac arrest • Survivors often develop postpolio syndrome many years later, as neurons are lost ...
Minireviews Cracking the Egg: Potential of the Developing Chicken
... failures, whereas lack of efficacy is the other major cause of attrition (Kola and Landis, 2004). The fact that several drug candidates progressed well into clinical trials before rare and potentially lethal adverse effects were detected led to an extension of nonclinical trials and the foundation o ...
... failures, whereas lack of efficacy is the other major cause of attrition (Kola and Landis, 2004). The fact that several drug candidates progressed well into clinical trials before rare and potentially lethal adverse effects were detected led to an extension of nonclinical trials and the foundation o ...