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The Motor System of the Cortex and the Brain Stem
The Motor System of the Cortex and the Brain Stem

... direction, discharge was minimal. Therefore, the discharge during the delay period appeared to be related in some way to the target’s position. Importantly, after the go signal was given, the discharge remained the same as it was during the delay period. This second observation suggests that the in ...
Pathways for emotions and memory
Pathways for emotions and memory

... The anterior thalamic nuclei are an integral component of the classic Papez circuit for emotions (for reviews see Papez, 1937; Ploog, 1989; Armstrong, 1990). In addition, the anterior thalamic nuclei play an important role in memory (Mair et al., 1979; Mayes et al., 1988; Kopelman, 1995; Parker and ...
Distributed patterns of reactivation predict vividness of recollection.
Distributed patterns of reactivation predict vividness of recollection.

... reactivation increases linearly as a function of the number of details recalled for consciously retrieved images. These findings suggest that recollection and reactivation are different facets (one subjective, one objective) of the same underlying brain processes, but more evidence is needed. With t ...
New Drugs from Old
New Drugs from Old

... Cardura XL • In the UK, licensed for hypertension & BPH • Claimed advantages are reduced risk of hypotension due to lower peak blood levels • Combined results of two double-blind RCTs (705 patients) suggest immediate release doxazosin is as effective with no significant difference in adverse effect ...
A Novel Mechanism and Treatment Target for Presynaptic
A Novel Mechanism and Treatment Target for Presynaptic

... critically important. Functional imaging provides evidence of fronto-striatal dysfunction in schizophrenia, with altered patterns of activation and impaired cognition (Manoach et al, 2000; Tost et al, 2005). Presynaptic terminals in the striatum have lower than expected levels of glutamate transport ...
CHRONIC TREATMENT OF DIABECON IN THE REGULATION OF ALLOXAN INDUCED
CHRONIC TREATMENT OF DIABECON IN THE REGULATION OF ALLOXAN INDUCED

... in vitro assays also supported free radical inhibition/scavenging potential of test drug at different concentrations, that can be compared with other polyherbal drugs[7, 9]. Generally, in vitro free radical scavenging effects are studied to see antioxidative efficiency of the test formulation[6,7,19 ...
The subfornical organ: A central nervous system site for actions of
The subfornical organ: A central nervous system site for actions of

... The leptin receptor, encoded by the Ob-R gene, was isolated from choroid plexus by expression cloning and is a member of the cytokine family (48). Although five leptin receptor isoforms have been identified (Ob-Ra to Ob-Re), only the long form of the receptor, Ob-Rb, possesses the cytoplasmic domain ...
Medical Management of Early PD - The Movement Disorder Society
Medical Management of Early PD - The Movement Disorder Society

... Relatively weak clinical effect but long-acting as compared to levodopa Mostly D2-receptor agonists Cause severe psychosis, confusion and sedation in elderly (especially above 70 years) May cause impulse control disturbances (gambling, hypersexuality, compulsive shopping, …) (Vilas, Parkinsonism Rel ...
PDF here
PDF here

... E-mail address: [email protected] (J.D. Glass). 0014-4886/$ - see front matter D 2003 Elsevier Inc. All rights reserved. doi:10.1016/j.expneurol.2003.10.004 ...
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K

... The gray matter of the higher brain undergoes spreading depolarization in response to ischemia, which increases metabolic demand and so promotes acute neuronal injury. The molecular mechanism linking ischemic failure of the Na+/K+ pump to the subsequent onset of a large inward current in neurons has ...
Neural Coding and Auditory Perception
Neural Coding and Auditory Perception

... these modulations [10]. To assess the effect of reverberation on the neural coding of amplitude envelope, we recorded from single units in the IC of awake rabbit using 100% sinusoidally amplitude modulated broadband noise stimuli presented in simulated anechoic and reverberant environments. The modu ...
rajiv gandhi university of health sciences, karnataka
rajiv gandhi university of health sciences, karnataka

ADVERSE REACTIONS - Dentalelle Tutoring
ADVERSE REACTIONS - Dentalelle Tutoring

... for the opioid analgesic by name and says that this is the only drug that works for them.  Claims allergies to NSAIDs .  Cancels dental appointment but still requests the opioid analgesic even though they will be “out of town on business”.  Experiences pain for days after scaling and root planing ...
Anxiolytic action on the behavioural inhibition system implies
Anxiolytic action on the behavioural inhibition system implies

... see the hippocampal formation as being critically involved in particular kinds of cognitive processing (e.g. of relations between stimuli in the Cohen and Eichenbaum case). This emphasis on processing as opposed to storage brings these recent theories very close to the updated version of our theory ...
Metabolizing Enzymes and Transporter Proteins: How
Metabolizing Enzymes and Transporter Proteins: How

... drug interactions is the CYP group. Enzyme inhibition leads to decreased drug metabolism, which in turn, increases the drug levels in the body. Identifying the type of inhibition may help counter it during clinical drug administration. On the other hand, a more complex phenomenon that can lead to dr ...
Use of textile biomaterials for the topic treatment of chronic venous
Use of textile biomaterials for the topic treatment of chronic venous

... treatment in the obtained grafted structures. Many aspects that may impact on the biomaterials efficiency have been investigated: type of textile, fiber composition, finishing technology, the way of grafting the polymer on the textile support and the way of including the drugs.In particular, we were ...
Patterns of neuronal migration in the embryonic cortex
Patterns of neuronal migration in the embryonic cortex

... understanding the patterns of neuronal migration in the developing cerebral cortex. Studies based largely on realtime imaging of migrating neurons in situ in both rodent and primate cortex have contributed significantly to a more complete description of the routes that neurons take to reach their pr ...
Importance of NMDA Receptor Activation During Initial
Importance of NMDA Receptor Activation During Initial

Atonia-Related Regions in the Rodent Pons and Medulla
Atonia-Related Regions in the Rodent Pons and Medulla

... Muscle-tone suppressions induced by pontomedullary stimulation were a function of the intensity (Figs. 3 and 4) and frequency of the stimulation (Fig. 3). Current intensity thresholds that produced muscle-tone suppression varied from 5 to 100 ␮A across the animals. Therefore, current values were nor ...
Presentation
Presentation

... • Suggested signaling pathway: GHSR ...
judasMRT99
judasMRT99

... in proliferation, differentiation, axon outgrowth, synaptogenesis, activity-dependent refinement of synaptic circuits, and programmed cell death. For example, NO mediates the switch from proliferation to cytostasis during the terminal differentiation of neuronal precursor cells (Peunova and Enikolop ...
Weber`s Syndrome Due to Low
Weber`s Syndrome Due to Low

... treatment, there was complete resolution of his symptoms [4]. In contrast, our patient's neurologic de icits have not improved despite initial chemotherapy. Brainstem gliomas account for only 1-2% of all intracranial gliomas in adults [5]. This may partially account for why glial tumors rarely manif ...
Mirror neuron functioning: an explanation for
Mirror neuron functioning: an explanation for

... Research as described above does makes it likely to believe that humans are in the possession of a system resembling to the one found in monkeys. However, a recent article by Turella and colleagues (2007) argues that from the great range of research on the topic of mirror neurons in humans, due to i ...
Anti-inflammatory, Antirheumatoid and Related Agents
Anti-inflammatory, Antirheumatoid and Related Agents

... glucocorticoids play an important role in preventing potential damaging effects of an unopposed inflammatory response and can be exploited therapeutically ...
Practitioner Brochure
Practitioner Brochure

... • Calories were controlled in the second period Studies show that 5 HTP's effectiveness is comparable to SSRIs like Prozac. Also gets results similar to the tricyclic antidepressants like Elavil. • Primary fibromyalgia syndrome is characterized by general musculoskeletal aching, multiple tender poin ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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